ATE222914T1 - Diester-derivate von acyclovir - Google Patents

Diester-derivate von acyclovir

Info

Publication number
ATE222914T1
ATE222914T1 AT98921224T AT98921224T ATE222914T1 AT E222914 T1 ATE222914 T1 AT E222914T1 AT 98921224 T AT98921224 T AT 98921224T AT 98921224 T AT98921224 T AT 98921224T AT E222914 T1 ATE222914 T1 AT E222914T1
Authority
AT
Austria
Prior art keywords
acyclovir
hydroxy
animal
individual
disclosed
Prior art date
Application number
AT98921224T
Other languages
English (en)
Inventor
Arnold Glazier
Milka Yanachkova
Ivan Yanachkov
Original Assignee
Drug Innovation & Design Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drug Innovation & Design Inc filed Critical Drug Innovation & Design Inc
Application granted granted Critical
Publication of ATE222914T1 publication Critical patent/ATE222914T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT98921224T 1997-05-15 1998-05-15 Diester-derivate von acyclovir ATE222914T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85715097A 1997-05-15 1997-05-15
US5022098A 1998-03-27 1998-03-27
PCT/US1998/009944 WO1998051692A1 (en) 1997-05-15 1998-05-15 Acyclovir diester derivatives

Publications (1)

Publication Number Publication Date
ATE222914T1 true ATE222914T1 (de) 2002-09-15

Family

ID=26728027

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98921224T ATE222914T1 (de) 1997-05-15 1998-05-15 Diester-derivate von acyclovir

Country Status (8)

Country Link
US (2) US6031096A (de)
EP (1) EP0981532B1 (de)
JP (1) JP2001527561A (de)
AT (1) ATE222914T1 (de)
AU (1) AU731225C (de)
CA (1) CA2289969A1 (de)
DE (1) DE69807464T2 (de)
WO (1) WO1998051692A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
WO1998051692A1 (en) * 1997-05-15 1998-11-19 Drug Innovation & Design, Inc. Acyclovir diester derivatives
BRPI0003386B8 (pt) * 2000-08-08 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda pró-droga homo ou heterodiméricas úteis no tratamento de doenças ou disfunções mediadas por fosfodiesterases; composições farmacêuticas contendo a pró-droga ou seus sais farmacêuticos aceitáveis; processo de obtenção destas pró-drogas
US8010843B2 (en) * 2005-12-14 2011-08-30 American Megatrends, Inc. System and method for debugging a target computer using SMBus
JP5519645B2 (ja) 2008-05-20 2014-06-11 ニューロジェシックス， インコーポレイテッド カーボネートプロドラッグおよびそれを使用する方法
JP5757864B2 (ja) 2008-05-20 2015-08-05 ニューロジェシックス， インコーポレイテッド 水溶性アセトアミノフェン類似体

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4146715A (en) * 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
US4816447A (en) * 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
IT1170232B (it) * 1983-10-31 1987-06-03 Anna Gioia Stendardi Composizioni terapeutiche ad attivita' antivirale
US4806642A (en) * 1984-10-05 1989-02-21 Warner-Lambert Company Purine derivatives
US4845084A (en) * 1984-01-26 1989-07-04 Merck & Co., Inc. Phosphate derivatives of substituted butyl guanines, antiviral compositions containing them, and methods of treating viral infections with them
EP0353955A3 (de) * 1988-08-02 1991-08-14 Beecham Group Plc Chemische Verbindungen
DK24089D0 (da) * 1989-01-20 1989-01-20 Hans Bundgaard Novel prodrug derivatives of biologically active agents containing hydroxyl groups or nh-acidic groups
US5627165A (en) * 1990-06-13 1997-05-06 Drug Innovation & Design, Inc. Phosphorous prodrugs and therapeutic delivery systems using same
ES2083580T3 (es) * 1990-06-13 1996-04-16 Arnold Glazier Profarmacos de fosforo.
US5879700A (en) * 1991-10-15 1999-03-09 Hostetler; Karl Y. Nucleoside analogue phosphates for topical use
US5580571A (en) * 1991-10-15 1996-12-03 Hostetler; Karl Y. Nucleoside analogues
US5627185A (en) * 1994-11-23 1997-05-06 Gosselin; Gilles Acyclovir derivatives as antiviral agents
US5789589A (en) * 1996-04-22 1998-08-04 Drug Innovation & Design, Inc. Guanine analog phosphates
WO1998051692A1 (en) * 1997-05-15 1998-11-19 Drug Innovation & Design, Inc. Acyclovir diester derivatives

Also Published As

Publication number Publication date
EP0981532B1 (de) 2002-08-28
AU7388598A (en) 1998-12-08
US6214811B1 (en) 2001-04-10
WO1998051692A1 (en) 1998-11-19
AU731225B2 (en) 2001-03-29
CA2289969A1 (en) 1998-11-19
DE69807464T2 (de) 2003-05-15
DE69807464D1 (de) 2002-10-02
US6031096A (en) 2000-02-29
AU731225C (en) 2001-10-18
EP0981532A1 (de) 2000-03-01
JP2001527561A (ja) 2001-12-25

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Legal Events

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