ATE223043T1 - Verfahren und reagenszusammensetzung zur durchführung von differenzierenden leukocytzählungen in frischen und gealteren vollblutproben, auf der grundlage der bereitsvorhandenen peroxidaseaktivität der leukocyten - Google Patents
Verfahren und reagenszusammensetzung zur durchführung von differenzierenden leukocytzählungen in frischen und gealteren vollblutproben, auf der grundlage der bereitsvorhandenen peroxidaseaktivität der leukocytenInfo
- Publication number
- ATE223043T1 ATE223043T1 AT96106957T AT96106957T ATE223043T1 AT E223043 T1 ATE223043 T1 AT E223043T1 AT 96106957 T AT96106957 T AT 96106957T AT 96106957 T AT96106957 T AT 96106957T AT E223043 T1 ATE223043 T1 AT E223043T1
- Authority
- AT
- Austria
- Prior art keywords
- reagent composition
- blood samples
- fresh
- analysis
- whole blood
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/106664—Blood serum or blood plasma standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Ecology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/442,491 US5639630A (en) | 1995-05-16 | 1995-05-16 | Method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE223043T1 true ATE223043T1 (de) | 2002-09-15 |
Family
ID=23756987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96106957T ATE223043T1 (de) | 1995-05-16 | 1996-05-03 | Verfahren und reagenszusammensetzung zur durchführung von differenzierenden leukocytzählungen in frischen und gealteren vollblutproben, auf der grundlage der bereitsvorhandenen peroxidaseaktivität der leukocyten |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5639630A (de) |
| EP (1) | EP0743519B1 (de) |
| JP (1) | JP4361142B2 (de) |
| KR (1) | KR960042055A (de) |
| AT (1) | ATE223043T1 (de) |
| AU (1) | AU699086C (de) |
| CA (1) | CA2173519A1 (de) |
| DE (1) | DE69623174T2 (de) |
| ES (1) | ES2181821T3 (de) |
| IL (1) | IL117862A (de) |
| PT (1) | PT743519E (de) |
| TW (1) | TW448295B (de) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5888752A (en) * | 1995-05-16 | 1999-03-30 | Bayer Corporation | Universal rinse reagent and method for use in hematological analyses of whole blood samples |
| US5843608A (en) * | 1995-06-08 | 1998-12-01 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
| US5817518A (en) * | 1995-12-18 | 1998-10-06 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
| US5830701A (en) * | 1997-03-28 | 1998-11-03 | Tao Medical Electronics Co., Ltd. | Method of detecting hematopoietic progenitor cells |
| JP3830613B2 (ja) | 1997-04-18 | 2006-10-04 | シスメックス株式会社 | 血液中の白血球及びヘモグロビン濃度測定試薬 |
| US5858794A (en) * | 1997-05-13 | 1999-01-12 | Bayer Corporation | Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers |
| US7494816B2 (en) | 1997-12-22 | 2009-02-24 | Roche Diagnostic Operations, Inc. | System and method for determining a temperature during analyte measurement |
| US8071384B2 (en) * | 1997-12-22 | 2011-12-06 | Roche Diagnostics Operations, Inc. | Control and calibration solutions and methods for their use |
| DE69917779T2 (de) * | 1998-06-30 | 2005-06-16 | Lamina, Inc. | Zytologische und histologische fixier-zusammensetzung und verfahren zur verwendung |
| FR2782166B1 (fr) * | 1998-08-04 | 2000-10-06 | Abx Sa | Reactif pour la mesure de l'hemoglobine et la determination des leucocytes dans un echantillon de sang |
| AU756780B2 (en) | 1999-03-29 | 2003-01-23 | Asahi Kasei Kabushiki Kaisha | Method for determining a while blood cell count of a whole blood sample |
| US6225124B1 (en) * | 1999-06-02 | 2001-05-01 | Sysmex Corporation | Diluting reagent and method compelling time-independent consistency in MCV assay |
| US6632676B1 (en) * | 1999-09-24 | 2003-10-14 | Clinical Diagnostic Solutions | Multi-purpose reagent system and method for enumeration of red blood cells, white blood cells and thrombocytes and differential determination of white blood cells |
| JP2004502434A (ja) | 2000-07-04 | 2004-01-29 | バイオイメージ エイ/エス | 細胞成分間の相互作用に関する量的情報の抽出方法 |
| CA2447586A1 (en) * | 2002-11-01 | 2004-05-01 | Streck Laboratories, Inc. | Improved hematology reagent and methods |
| US7723099B2 (en) * | 2003-09-10 | 2010-05-25 | Abbott Point Of Care Inc. | Immunoassay device with immuno-reference electrode |
| US7803523B2 (en) * | 2004-08-27 | 2010-09-28 | University Health Network | Whole blood preparation for cytometric analysis of cell signaling pathways |
| ES2445148T3 (es) * | 2004-09-01 | 2014-02-28 | Maine Standards Company Llc | Patrones de lípidos estables novedosos |
| US7625757B2 (en) | 2006-01-27 | 2009-12-01 | Sysmex Corporation | Reagent for immature leukocyte analysis and reagent kit |
| CN101078720B (zh) * | 2006-05-22 | 2010-12-01 | 深圳迈瑞生物医疗电子股份有限公司 | 一种改进的用于对白细胞进行分类的试剂及方法 |
| CN101078721B (zh) * | 2006-05-23 | 2010-12-22 | 深圳迈瑞生物医疗电子股份有限公司 | 对白细胞进行分类的试剂及方法 |
| EP2030013B1 (de) * | 2006-06-06 | 2009-12-16 | Roche Diagnostics GmbH | Gebrauchsfertiges sammelgefäss für vollblut |
| US20080026366A1 (en) * | 2006-06-07 | 2008-01-31 | Newcomer Supply, Inc. | Biological fixative and method of using the biological fixative |
| US7449337B2 (en) * | 2007-01-24 | 2008-11-11 | Idexx Laboratories, Inc. | Lytic reagent and method for leukocytes differential in whole blood |
| CN101311725B (zh) * | 2007-05-25 | 2014-03-26 | 深圳迈瑞生物医疗电子股份有限公司 | 一种五分类白细胞质控物及其制备方法 |
| CN101349644B (zh) * | 2007-07-20 | 2012-06-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种白细胞分类试剂和其使用方法 |
| US9814422B2 (en) | 2007-08-06 | 2017-11-14 | The Regents Of The University Of California | Compositions for solubilizing cells and/or tissue |
| US8642664B2 (en) | 2007-08-06 | 2014-02-04 | Samir Mitragotri | Composition for solubilizing tissue and cells comprising N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate and polyoxyethylene (10) cetyl ether |
| WO2009048681A2 (en) | 2007-08-06 | 2009-04-16 | The Regents Of The University Of California | Methods of tissue-based diagnosis |
| US8102161B2 (en) * | 2007-09-25 | 2012-01-24 | Tdk Corporation | Stable output in a switching power supply by smoothing the output of the secondary coil |
| CN101475754A (zh) * | 2008-01-04 | 2009-07-08 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类荧光染料,组合物及在生物样品染色中的用途 |
| CN101602762B (zh) * | 2008-06-10 | 2013-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类化合物、其制备方法及应用 |
| CN101726579B (zh) * | 2008-10-17 | 2014-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 血液检测试剂和方法 |
| US8367358B2 (en) * | 2008-12-17 | 2013-02-05 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Reagent, kit and method for differentiating and counting leukocytes |
| EP2396654B1 (de) | 2009-02-13 | 2016-02-10 | The Regents of The University of California | Zusammensetzung und Verfahren für die gewebebasierte Diagnose |
| CN101988082B (zh) * | 2009-07-31 | 2015-04-08 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法 |
| US9091677B2 (en) | 2010-08-09 | 2015-07-28 | Beckman Coulter, Inc. | Isotonic buffered composition and method that enables counting of cells |
| CN104245952B (zh) * | 2012-03-30 | 2017-08-29 | 积水医疗株式会社 | 血液样品中的物质的测定法 |
| KR102099487B1 (ko) * | 2012-05-16 | 2020-04-09 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 세포 및/또는 조직을 가용화시키기 위한 조성물 |
| EP2972321B1 (de) * | 2013-03-12 | 2021-02-17 | Abbott Laboratories | System zur untersuchung weisser blutkörperchen |
| BE1021926B1 (nl) * | 2014-04-01 | 2016-01-27 | FertiPro N.V. | Werkijze voor semenanalyse |
| WO2019111355A1 (ja) | 2017-12-06 | 2019-06-13 | オリンパス株式会社 | 学習モデル作成方法、画像処理方法、学習モデル作成装置、画像処理装置、学習モデル作成プログラム、及び画像処理プログラム |
| JP7143678B2 (ja) * | 2018-08-24 | 2022-09-29 | 東ソー株式会社 | 標的細胞を検出する方法 |
| WO2020042027A1 (zh) * | 2018-08-29 | 2020-03-05 | 深圳迈瑞生物医疗电子股份有限公司 | 血液样本检测的方法、血液样本检测仪和存储介质 |
| WO2020252692A1 (zh) * | 2019-06-19 | 2020-12-24 | 深圳迈瑞生物医疗电子股份有限公司 | 一种细胞分析仪、基于阻抗法对白细胞进行分类的方法及计算机可读存储介质 |
| CN111239120A (zh) * | 2020-02-26 | 2020-06-05 | 绍兴市人民医院 | 一种血液钙离子检测试纸 |
| US12498371B2 (en) | 2021-12-23 | 2025-12-16 | Hi Technologies Ltda | Formulation for total and differential counting of leukocytes in liquid medium and method of making and using same |
| WO2025202842A1 (en) * | 2024-03-26 | 2025-10-02 | Asima Health Inc. | Cancer-staging method using impedance spectroscopy |
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| US3741875A (en) * | 1970-10-30 | 1973-06-26 | Mount Sinai Res Foundation Inc | Process and apparatus for obtaining a differential white blood cell count |
| US4099917A (en) * | 1977-07-21 | 1978-07-11 | Technicon Instruments Corporation | Process for preparing a cell suspension from blood for discrimination of white blood cells and platelets from other blood particles |
| US4506018A (en) * | 1982-12-30 | 1985-03-19 | Becton, Dickinson And Company | Blood diluent |
| CA1255197A (en) * | 1984-09-24 | 1989-06-06 | Joseph L. Orlik | Leukocyte differentiation composition and method |
| US4801549A (en) * | 1985-09-06 | 1989-01-31 | Technicon Instruments Corporation | Method for the determination of a differential white blood cell count |
| AU602129B2 (en) * | 1985-09-06 | 1990-10-04 | Technicon Instruments Corportion | Method for the determination of a differential white blood cell count |
| US4978624A (en) * | 1985-09-06 | 1990-12-18 | Technicon Instruments Corporation | Reagent for the determination of a differential white blood cell count |
| US5426029A (en) * | 1986-03-31 | 1995-06-20 | T Cell Diagnostics, Inc. | Therapeutic and diagnostic methods using leukocyte surface antigens |
| US5262302A (en) * | 1987-03-13 | 1993-11-16 | Coulter Corporation | Method for screening white blood cells |
| US5389549A (en) * | 1987-05-29 | 1995-02-14 | Toa Medical Electronics Co., Ltd. | Method for classifying leukocytes and a reagent used therefor |
| EP0316453B1 (de) * | 1987-05-29 | 1996-03-27 | Toa Medical Electronics Co., Ltd. | Verfahren zum klassifizieren von leukozyten und reagenzien |
| JP2619900B2 (ja) * | 1988-01-27 | 1997-06-11 | 東亜医用電子株式会社 | 血液中の白血球およびヘモグロビンの測定用試薬および方法 |
| CA2016699C (en) * | 1989-05-15 | 2003-11-18 | Paul N. Marshall | Lytic agents and uses thereof |
| US5116734A (en) * | 1989-09-01 | 1992-05-26 | Digene Diagnostics, Inc. | Highly sensitive method for detecting peroxidase |
| IT8921788A0 (it) * | 1989-09-21 | 1989-09-21 | Diesse Diagnostica | Reattivo utile per la rilevazione e la determinazione quantitativa dei leucociti in fluidi biologici. |
| FR2654744B1 (fr) * | 1989-11-20 | 1992-03-13 | Abx Sa | Reactif et methode d'utilisation de celui-ci pour la determination automatique en cytometrie de flux d'au moins une sous-population leucocytaire a partir du sang total. |
| US5227304A (en) * | 1991-01-16 | 1993-07-13 | Sequoia Turner Corporation | Method for counting whole blood diluent and detergent reagent system |
| JP3048260B2 (ja) * | 1991-07-29 | 2000-06-05 | シスメックス株式会社 | 白血球分類計数用試料調製方法 |
| US5525461A (en) * | 1991-11-01 | 1996-06-11 | T Cell Diagnostics, Inc. | Therapeutic and diagnostic methods using total leukocyte surface antigens |
| JP3467310B2 (ja) * | 1994-04-21 | 2003-11-17 | シスメックス株式会社 | 白血球分析用試薬及び白血球の分類方法 |
-
1995
- 1995-05-16 US US08/442,491 patent/US5639630A/en not_active Expired - Lifetime
-
1996
- 1996-04-04 CA CA002173519A patent/CA2173519A1/en not_active Abandoned
- 1996-04-09 IL IL11786296A patent/IL117862A/xx not_active IP Right Cessation
- 1996-04-17 TW TW085104571A patent/TW448295B/zh not_active IP Right Cessation
- 1996-05-03 PT PT96106957T patent/PT743519E/pt unknown
- 1996-05-03 AT AT96106957T patent/ATE223043T1/de not_active IP Right Cessation
- 1996-05-03 DE DE69623174T patent/DE69623174T2/de not_active Expired - Lifetime
- 1996-05-03 EP EP96106957A patent/EP0743519B1/de not_active Expired - Lifetime
- 1996-05-03 ES ES96106957T patent/ES2181821T3/es not_active Expired - Lifetime
- 1996-05-13 AU AU52262/96A patent/AU699086C/en not_active Ceased
- 1996-05-16 KR KR1019960016922A patent/KR960042055A/ko not_active Ceased
- 1996-05-16 JP JP14482696A patent/JP4361142B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU5226296A (en) | 1996-11-28 |
| ES2181821T3 (es) | 2003-03-01 |
| JP4361142B2 (ja) | 2009-11-11 |
| AU699086B2 (en) | 1998-11-19 |
| DE69623174D1 (de) | 2002-10-02 |
| PT743519E (pt) | 2002-12-31 |
| DE69623174T2 (de) | 2002-12-19 |
| EP0743519B1 (de) | 2002-08-28 |
| KR960042055A (ko) | 1996-12-19 |
| TW448295B (en) | 2001-08-01 |
| EP0743519A3 (de) | 1998-07-29 |
| IL117862A0 (en) | 1996-08-04 |
| CA2173519A1 (en) | 1996-11-17 |
| AU699086C (en) | 2001-06-21 |
| JPH08308593A (ja) | 1996-11-26 |
| US5639630A (en) | 1997-06-17 |
| IL117862A (en) | 1999-12-22 |
| EP0743519A2 (de) | 1996-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |