ATE223410T1 - Biaryl-pyridochinazolinonderivate als antikrebsmittel - Google Patents

Biaryl-pyridochinazolinonderivate als antikrebsmittel

Info

Publication number: ATE223410T1
Authority: AT; Austria
Prior art keywords: alkyl; phenanthrenyl; group; pyridoquinazolinone; biaryl
Prior art date: 1996-11-26

Application number

AT97953115T

Other languages

English (en)

Inventor

Michael Peter Trova

Nan Zhang

Douglas Bruce Kitchen

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-26

Filing date

1997-11-24

Publication date

2002-09-15

1997-11-24 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

2002-09-15 Application granted granted Critical

2002-09-15 Publication of ATE223410T1 publication Critical patent/ATE223410T1/de

Links

239000002246 antineoplastic agent Substances 0.000 title abstract 2
-1 1-phenanthrenyl Chemical group 0.000 abstract 6
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 abstract 1
125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 abstract 1
229910006069 SO3H Inorganic materials 0.000 abstract 1
229940034982 antineoplastic agent Drugs 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT97953115T 1996-11-26 1997-11-24 Biaryl-pyridochinazolinonderivate als antikrebsmittel ATE223410T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US75686096A	1996-11-26	1996-11-26
PCT/US1997/022501 WO1998023616A1 (en)	1996-11-26	1997-11-24	Biaryl-pyridoquinazolinone derivatives as anti-cancer agents

Publications (1)

Publication Number	Publication Date
ATE223410T1 true ATE223410T1 (de)	2002-09-15

Family

ID=25045369

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97953115T ATE223410T1 (de)	1996-11-26	1997-11-24	Biaryl-pyridochinazolinonderivate als antikrebsmittel

Country Status (10)

Country	Link
EP (1)	EP0944629B1 (de)
JP (1)	JP2001507340A (de)
AT (1)	ATE223410T1 (de)
AU (1)	AU5692298A (de)
CA (1)	CA2272916A1 (de)
DE (1)	DE69715241T2 (de)
DK (1)	DK0944629T3 (de)
ES (1)	ES2181053T3 (de)
PT (1)	PT944629E (de)
WO (1)	WO1998023616A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6413971B1 (en) *	1996-11-27	2002-07-02	Pfizer Inc	Fused bicyclic pyrimidine derivatives
GB2360280B (en) *	2000-03-06	2004-07-28	Xenova Ltd	Heteroaromatic [a] phenazine carboxamides as topoisomerase inhibitors

1997
- 1997-11-24 EP EP97953115A patent/EP0944629B1/de not_active Expired - Lifetime
- 1997-11-24 AU AU56922/98A patent/AU5692298A/en not_active Abandoned
- 1997-11-24 WO PCT/US1997/022501 patent/WO1998023616A1/en not_active Ceased
- 1997-11-24 AT AT97953115T patent/ATE223410T1/de not_active IP Right Cessation
- 1997-11-24 PT PT97953115T patent/PT944629E/pt unknown
- 1997-11-24 DE DE69715241T patent/DE69715241T2/de not_active Expired - Fee Related
- 1997-11-24 DK DK97953115T patent/DK0944629T3/da active
- 1997-11-24 JP JP52492898A patent/JP2001507340A/ja active Pending
- 1997-11-24 CA CA002272916A patent/CA2272916A1/en not_active Abandoned
- 1997-11-24 ES ES97953115T patent/ES2181053T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO1998023616A1 (en)	1998-06-04
EP0944629B1 (de)	2002-09-04
DE69715241D1 (de)	2002-10-10
JP2001507340A (ja)	2001-06-05
HK1022476A1 (en)	2000-08-11
CA2272916A1 (en)	1998-06-04
DE69715241T2 (de)	2003-01-02
AU5692298A (en)	1998-06-22
ES2181053T3 (es)	2003-02-16
PT944629E (pt)	2002-12-31
EP0944629A1 (de)	1999-09-29
DK0944629T3 (da)	2002-12-30

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Legal Events

Date	Code	Title	Description
2003-01-15	UEP	Publication of translation of european patent specification
2004-08-15	REN	Ceased due to non-payment of the annual fee