DK0944629T3 - Biaryl-pyridoquinazolinonderivater som anti-cancermidler - Google Patents
Biaryl-pyridoquinazolinonderivater som anti-cancermidlerInfo
- Publication number
- DK0944629T3 DK0944629T3 DK97953115T DK97953115T DK0944629T3 DK 0944629 T3 DK0944629 T3 DK 0944629T3 DK 97953115 T DK97953115 T DK 97953115T DK 97953115 T DK97953115 T DK 97953115T DK 0944629 T3 DK0944629 T3 DK 0944629T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- phenanthrenyl
- group
- pyridoquinazolinone
- biaryl
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- -1 1-phenanthrenyl Chemical group 0.000 abstract 6
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 abstract 1
- 125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 abstract 1
- 229910006069 SO3H Inorganic materials 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75686096A | 1996-11-26 | 1996-11-26 | |
| PCT/US1997/022501 WO1998023616A1 (en) | 1996-11-26 | 1997-11-24 | Biaryl-pyridoquinazolinone derivatives as anti-cancer agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0944629T3 true DK0944629T3 (da) | 2002-12-30 |
Family
ID=25045369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97953115T DK0944629T3 (da) | 1996-11-26 | 1997-11-24 | Biaryl-pyridoquinazolinonderivater som anti-cancermidler |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0944629B1 (da) |
| JP (1) | JP2001507340A (da) |
| AT (1) | ATE223410T1 (da) |
| AU (1) | AU5692298A (da) |
| CA (1) | CA2272916A1 (da) |
| DE (1) | DE69715241T2 (da) |
| DK (1) | DK0944629T3 (da) |
| ES (1) | ES2181053T3 (da) |
| PT (1) | PT944629E (da) |
| WO (1) | WO1998023616A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL129825A0 (en) * | 1996-11-27 | 2000-02-29 | Pfizer | Fused bicyclic pyrimidine derivatives |
| GB2360280B (en) * | 2000-03-06 | 2004-07-28 | Xenova Ltd | Heteroaromatic [a] phenazine carboxamides as topoisomerase inhibitors |
-
1997
- 1997-11-24 CA CA002272916A patent/CA2272916A1/en not_active Abandoned
- 1997-11-24 AT AT97953115T patent/ATE223410T1/de not_active IP Right Cessation
- 1997-11-24 WO PCT/US1997/022501 patent/WO1998023616A1/en not_active Ceased
- 1997-11-24 PT PT97953115T patent/PT944629E/pt unknown
- 1997-11-24 AU AU56922/98A patent/AU5692298A/en not_active Abandoned
- 1997-11-24 DE DE69715241T patent/DE69715241T2/de not_active Expired - Fee Related
- 1997-11-24 DK DK97953115T patent/DK0944629T3/da active
- 1997-11-24 JP JP52492898A patent/JP2001507340A/ja active Pending
- 1997-11-24 EP EP97953115A patent/EP0944629B1/en not_active Expired - Lifetime
- 1997-11-24 ES ES97953115T patent/ES2181053T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0944629B1 (en) | 2002-09-04 |
| EP0944629A1 (en) | 1999-09-29 |
| ATE223410T1 (de) | 2002-09-15 |
| WO1998023616A1 (en) | 1998-06-04 |
| DE69715241D1 (de) | 2002-10-10 |
| JP2001507340A (ja) | 2001-06-05 |
| CA2272916A1 (en) | 1998-06-04 |
| AU5692298A (en) | 1998-06-22 |
| HK1022476A1 (en) | 2000-08-11 |
| PT944629E (pt) | 2002-12-31 |
| DE69715241T2 (de) | 2003-01-02 |
| ES2181053T3 (es) | 2003-02-16 |
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