ATE223418T1 - 4'-substituierte-4',5'-dihydropsoralene und deren therapeutische verwendung - Google Patents

4'-substituierte-4',5'-dihydropsoralene und deren therapeutische verwendung

Info

Publication number: ATE223418T1
Authority: AT; Austria
Prior art keywords: substituted; mammal; aromatic ring; nitrogen form; heterocyclic aromatic
Prior art date: 1998-11-30

Application number

AT99962909T

Other languages

English (en)

Inventor

Ned D Heindel

Marilyn S Whittemore

Christophe Guillon

Robert D Rapp

Jeffrey D Laskin

Thomas E Mcneel

Diane E Heck

Original Assignee

Buckman Labor Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-30

Filing date

1999-11-30

Publication date

2002-09-15

1999-11-30 Application filed by Buckman Labor Inc filed Critical Buckman Labor Inc

2002-09-15 Application granted granted Critical

2002-09-15 Publication of ATE223418T1 publication Critical patent/ATE223418T1/de

Links

230000001225 therapeutic effect Effects 0.000 title 1
241000124008 Mammalia Species 0.000 abstract 3
125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 3
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000000623 heterocyclic group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
150000002431 hydrogen Chemical group 0.000 abstract 2
125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
230000009286 beneficial effect Effects 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
230000001678 irradiating effect Effects 0.000 abstract 1
230000000813 microbial effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000002062 proliferating effect Effects 0.000 abstract 1
208000017520 skin disease Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Steroid Compounds (AREA)
Saccharide Compounds (AREA)

AT99962909T 1998-11-30 1999-11-30 4'-substituierte-4',5'-dihydropsoralene und deren therapeutische verwendung ATE223418T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11033698P	1998-11-30	1998-11-30
PCT/US1999/028174 WO2000032603A1 (en)	1998-11-30	1999-11-30	4'-substituted-4',5'-dihydropsoralens and therapeutical uses thereof

Publications (1)

Publication Number	Publication Date
ATE223418T1 true ATE223418T1 (de)	2002-09-15

Family

ID=22332461

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99962909T ATE223418T1 (de)	1998-11-30	1999-11-30	4'-substituierte-4',5'-dihydropsoralene und deren therapeutische verwendung

Country Status (10)

Country	Link
US (1)	US6177424B1 (de)
EP (1)	EP1144417B1 (de)
AT (1)	ATE223418T1 (de)
AU (1)	AU1925500A (de)
CA (1)	CA2352258A1 (de)
DE (1)	DE69902821T2 (de)
ES (1)	ES2183636T3 (de)
MX (1)	MXPA01005363A (de)
PT (1)	PT1144417E (de)
WO (1)	WO2000032603A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN119950493B (zh) *	2025-03-14	2025-08-15	自然资源部第三海洋研究所	3,4-二氢补骨脂素在制备预防或治疗类风湿关节炎的药物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4130568A (en)	1976-09-14	1978-12-19	Hoffmann-La Roche Inc.	8-Methoxypsoralen derivatives
US4196281A (en)	1976-10-20	1980-04-01	Regents Of The University Of California	Psoralens
US4124598A (en)	1976-10-20	1978-11-07	Hoffmann-La Roche Inc.	Psoralens
US4294822A (en)	1980-07-29	1981-10-13	Thomas C. Elder, Inc.	5-Aminoalkyl-4,4,8-trialkylpsoralens
US4950770A (en)	1987-06-16	1990-08-21	Elder Pharmaceuticals, Inc.	Psoralens aminomethylation
US5216176A (en)	1989-01-23	1993-06-01	Lehigh University	7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor
US5356929A (en)	1989-01-23	1994-10-18	Lehigh University	Reduced and quaternized psoralens as photo-activated therapeutics
US5712085A (en)	1993-06-28	1998-01-27	Cerus Corporation	5'-(4-amino-2-oxa)butye-4,4', 8-trinethylpsoralen in synthetic medium
US5399719A (en) *	1993-06-28	1995-03-21	Steritech, Inc.	Compounds for the photodecontamination of pathogens in blood

1999
- 1999-11-30 ES ES99962909T patent/ES2183636T3/es not_active Expired - Lifetime
- 1999-11-30 WO PCT/US1999/028174 patent/WO2000032603A1/en not_active Ceased
- 1999-11-30 DE DE69902821T patent/DE69902821T2/de not_active Expired - Fee Related
- 1999-11-30 PT PT99962909T patent/PT1144417E/pt unknown
- 1999-11-30 MX MXPA01005363A patent/MXPA01005363A/es unknown
- 1999-11-30 AU AU19255/00A patent/AU1925500A/en not_active Abandoned
- 1999-11-30 AT AT99962909T patent/ATE223418T1/de not_active IP Right Cessation
- 1999-11-30 EP EP99962909A patent/EP1144417B1/de not_active Expired - Lifetime
- 1999-11-30 US US09/450,560 patent/US6177424B1/en not_active Expired - Fee Related
- 1999-11-30 CA CA002352258A patent/CA2352258A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU1925500A (en)	2000-06-19
EP1144417B1 (de)	2002-09-04
US6177424B1 (en)	2001-01-23
PT1144417E (pt)	2002-12-31
CA2352258A1 (en)	2000-06-08
WO2000032603A1 (en)	2000-06-08
MXPA01005363A (es)	2004-04-21
EP1144417A1 (de)	2001-10-17
DE69902821T2 (de)	2003-01-09
ES2183636T3 (es)	2003-03-16
DE69902821D1 (de)	2002-10-10

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Legal Events

Date	Code	Title	Description
2002-12-15	UEP	Publication of translation of european patent specification
2004-02-15	REN	Ceased due to non-payment of the annual fee