ATE223901T1 - Verfahren zur herstellung von 5,7 dichlor-4- hydroxychinolin - Google Patents
Verfahren zur herstellung von 5,7 dichlor-4- hydroxychinolinInfo
- Publication number
- ATE223901T1 ATE223901T1 AT95909989T AT95909989T ATE223901T1 AT E223901 T1 ATE223901 T1 AT E223901T1 AT 95909989 T AT95909989 T AT 95909989T AT 95909989 T AT95909989 T AT 95909989T AT E223901 T1 ATE223901 T1 AT E223901T1
- Authority
- AT
- Austria
- Prior art keywords
- hydroxyquinoline
- dichloro
- sulfuric
- producing
- dcqa
- Prior art date
Links
- GESHSYASHHORJB-UHFFFAOYSA-N 5,7-dichloro-1h-quinolin-4-one Chemical compound N1C=CC(=O)C=2C1=CC(Cl)=CC=2Cl GESHSYASHHORJB-UHFFFAOYSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 10
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 8
- 238000000034 method Methods 0.000 abstract 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 4
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 4
- ZGUZVDPXYSBFGE-UHFFFAOYSA-N ethyl 5,7-dichloro-4-oxo-1h-quinoline-3-carboxylate Chemical compound ClC1=CC(Cl)=C2C(=O)C(C(=O)OCC)=CNC2=C1 ZGUZVDPXYSBFGE-UHFFFAOYSA-N 0.000 abstract 3
- 230000000911 decarboxylating effect Effects 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- DEBOCPZCSPMQBS-UHFFFAOYSA-N 5,7-dichloro-4-oxo-1h-quinoline-3-carboxylic acid Chemical compound ClC1=CC(Cl)=C2C(=O)C(C(=O)O)=CNC2=C1 DEBOCPZCSPMQBS-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/30—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same unsaturated acyclic carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5441194 | 1994-03-01 | ||
| JP5441094 | 1994-03-01 | ||
| PCT/JP1995/000293 WO1995023787A1 (en) | 1994-03-01 | 1995-02-27 | Process for producing 5,7-dichloro-4-hydroxyquinoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE223901T1 true ATE223901T1 (de) | 2002-09-15 |
Family
ID=26395172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95909989T ATE223901T1 (de) | 1994-03-01 | 1995-02-27 | Verfahren zur herstellung von 5,7 dichlor-4- hydroxychinolin |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5731440A (de) |
| EP (1) | EP0748799B1 (de) |
| JP (1) | JP3676415B2 (de) |
| AT (1) | ATE223901T1 (de) |
| DE (1) | DE69528160T2 (de) |
| WO (1) | WO1995023787A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2783826B1 (fr) * | 1998-09-29 | 2002-07-19 | Rhodia Chimie Sa | Procede de preparation de 4-hydroxyquinoleines et/ou formes tautomeres |
| FR2786483B1 (fr) | 1998-12-01 | 2001-02-16 | Rhodia Chimie Sa | Procede de preparation de 4-hydroxyquinoleines et/ou formes tautomeres |
| EP1315702B1 (de) * | 2000-09-08 | 2004-11-10 | Dow AgroSciences LLC | Verfahren zur herstellung von halo-4-phenoxy-chinolinen |
| US20060020029A1 (en) * | 2004-07-02 | 2006-01-26 | Shimasaki Craig D | Pharmaceutical compositions from ethnobotanicals |
| KR20150115533A (ko) | 2014-04-04 | 2015-10-14 | 씨제이제일제당 (주) | 1,5-디아미노펜탄의 정제방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3981717A (en) * | 1969-09-24 | 1976-09-21 | American Cyanamid Company | Herbicidal methods |
| US4035368A (en) * | 1975-04-02 | 1977-07-12 | Riker Laboratories, Inc. | Substituted 3-(1H-tetrazol-5-yl)-quinoline compounds |
| HU170951B (hu) * | 1975-06-06 | 1977-10-28 | Chinoin Gyogyszer Es Vegyeszet | Novyj sposob poluchenija hinolin-3-karbonovykh kislot |
| US4252945A (en) * | 1979-07-11 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Process for preparing pyrazolo[1,5-c]-quinazoline derivatives and novel intermediates |
| JPS5630964A (en) * | 1979-08-22 | 1981-03-28 | Kyorin Pharmaceut Co Ltd | Novel substituted quinolinecarboxylic acid and its preparation |
| DE3028520A1 (de) * | 1980-07-28 | 1982-02-25 | Dynamit Nobel Ag, 5210 Troisdorf | Verfahren zur herstellung von chinolinen, naphtyridinen und anderen stickstoff-bi-heterocyclen |
| US4390541A (en) * | 1980-12-19 | 1983-06-28 | Lilly Industries Limited | Quinolone derivatives and their use in a method of controlling an immediate hypersensitivity disease |
| FR2498186A1 (fr) * | 1981-01-16 | 1982-07-23 | Rhone Poulenc Sante | Preparation de la chloro-5, -6, -7 ou -8 hydroxy-4 quinoleine |
| FR2537140B1 (fr) * | 1982-12-07 | 1986-07-18 | Roussel Uclaf | Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant |
| JPS63239269A (ja) * | 1986-11-21 | 1988-10-05 | Tokyo Tanabe Co Ltd | １，４−ジヒドロ−４−オキソキノリン化合物及びその製造法 |
| IL89029A (en) * | 1988-01-29 | 1993-01-31 | Lilly Co Eli | Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them |
| JPH02288864A (ja) * | 1988-05-24 | 1990-11-28 | Kirin Brewery Co Ltd | ４（１ｈ）キノロン誘導体 |
| US5081121A (en) * | 1988-05-24 | 1992-01-14 | Tatsushi Osawa | 4(1h)-quinolone derivatives |
-
1995
- 1995-02-27 WO PCT/JP1995/000293 patent/WO1995023787A1/ja not_active Ceased
- 1995-02-27 EP EP95909989A patent/EP0748799B1/de not_active Expired - Lifetime
- 1995-02-27 DE DE69528160T patent/DE69528160T2/de not_active Expired - Lifetime
- 1995-02-27 AT AT95909989T patent/ATE223901T1/de not_active IP Right Cessation
- 1995-02-27 US US08/700,363 patent/US5731440A/en not_active Expired - Lifetime
- 1995-02-27 JP JP06155095A patent/JP3676415B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69528160T2 (de) | 2003-02-06 |
| DE69528160D1 (de) | 2002-10-17 |
| WO1995023787A1 (en) | 1995-09-08 |
| EP0748799A1 (de) | 1996-12-18 |
| EP0748799A4 (de) | 1998-09-02 |
| JPH07291934A (ja) | 1995-11-07 |
| US5731440A (en) | 1998-03-24 |
| JP3676415B2 (ja) | 2005-07-27 |
| EP0748799B1 (de) | 2002-09-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE372383T1 (de) | Verfahren zur herstellung von l-aminosäuren | |
| DE69942140D1 (de) | Verfahren zur Herstellung von L-Aminosäuren | |
| DE60042375D1 (de) | Verfahren zur Herstellung von 3,3-Dimethylbutanal | |
| DE3876074D1 (de) | Verfahren zur herstellung von n-phosphonmethylglyzin. | |
| ATE223389T1 (de) | Verfahren zur herstellung von tetraazamakroringen | |
| ATE126829T1 (de) | Verfahren zur herstellung von salzen des l- ornithins. | |
| ATE196458T1 (de) | Verfahren zur herstellung von xylitol | |
| ATE264392T1 (de) | Verfahren zur herstellung von d-pantoinsäure und d-pantothensäure oder deren salze | |
| ATE341640T1 (de) | Verfahren zur herstellung von nicht-proteinogenen l-aminosäuren | |
| ATE164730T1 (de) | Verfahren zur herstellung eines pflanzlichen eiweisshydrolysats mit einer gasförmigen salzsäure und so hergestelltes produkt | |
| ATE312809T1 (de) | Verfahren zur herstellung von gabapentin | |
| DE69528160D1 (de) | Verfahren zur herstellung von 5,7 dichlor-4-hydroxychinolin | |
| DE69931493D1 (de) | Verfahren zur herstellung von hydroxymethylthiobuttersäure | |
| ATE191457T1 (de) | Verfahren zur herstellung von einem bicyclohexanderivat | |
| DE69822285D1 (de) | Verfahren zur Herstellung von vernetzter Hyaluronsäure | |
| DE69400696D1 (de) | Verfahren zur herstellung von eisenchlorid | |
| AT400035B (de) | Enzymatisches verfahren zur herstellung aliphatischer s-cyanhydrine | |
| ATE399152T1 (de) | Verfahren zur herstellung von optisch aktiven azetidin-2-carbonsäuren | |
| ATE140366T1 (de) | Verfahren zur herstellung von eines pflanzliches eiweisshydrolysat | |
| DE69404454D1 (de) | Verfahren zur herstellung von aminomethanphosphonsäure | |
| ATE233732T1 (de) | Verfahren zur herstellung von azetidin-2- carbonsäure und zwischenprodukten davon | |
| DE59807664D1 (de) | Verfahren zur herstellung von 3-cyano-2,4-dihalogen-5-fluor-benzoesäuren | |
| ATE258181T1 (de) | Verfahren zur herstellung von dinatrium pamidronat | |
| DE69718450D1 (de) | Einfaches verfahren zur herstellung von hochwertigem captropril | |
| DE69720432D1 (de) | Verfahren zur herstellung von 2-hydroxynaphtalin-3,6-dicarbonsaure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |