ATE224188T1 - Nicht-beta oxidierbare fettsäureanaloge,deren verwendung als therapeutisch wirksame medikamente sowie deren herstellung - Google Patents

Nicht-beta oxidierbare fettsäureanaloge,deren verwendung als therapeutisch wirksame medikamente sowie deren herstellung

Info

Publication number
ATE224188T1
ATE224188T1 AT95941241T AT95941241T ATE224188T1 AT E224188 T1 ATE224188 T1 AT E224188T1 AT 95941241 T AT95941241 T AT 95941241T AT 95941241 T AT95941241 T AT 95941241T AT E224188 T1 ATE224188 T1 AT E224188T1
Authority
AT
Austria
Prior art keywords
sub
beta
production
fatty acid
oxidizable fatty
Prior art date
Application number
AT95941241T
Other languages
English (en)
Inventor
Rolf Berge
Jon Songstad
Original Assignee
Rolf Berge
Jon Songstad
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rolf Berge, Jon Songstad filed Critical Rolf Berge
Application granted granted Critical
Publication of ATE224188T1 publication Critical patent/ATE224188T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95941241T 1995-07-14 1995-10-25 Nicht-beta oxidierbare fettsäureanaloge,deren verwendung als therapeutisch wirksame medikamente sowie deren herstellung ATE224188T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO952796A NO952796D0 (no) 1995-07-14 1995-07-14 Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater
PCT/NO1995/000195 WO1997003663A1 (en) 1995-07-14 1995-10-25 NON-β-OXIDIZABLE FATTY ACID ANALOGUES, THEIR USES AS THERAPEUTIC ACTIVE MEDICAMENTS, AND PREPARATION THEREOF

Publications (1)

Publication Number Publication Date
ATE224188T1 true ATE224188T1 (de) 2002-10-15

Family

ID=19898394

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95941241T ATE224188T1 (de) 1995-07-14 1995-10-25 Nicht-beta oxidierbare fettsäureanaloge,deren verwendung als therapeutisch wirksame medikamente sowie deren herstellung

Country Status (13)

Country Link
US (1) US6046237A (de)
EP (3) EP1232750A1 (de)
JP (1) JP3553966B2 (de)
KR (1) KR100394986B1 (de)
AT (1) ATE224188T1 (de)
AU (2) AU4272696A (de)
CA (1) CA2226871A1 (de)
DE (1) DE69528291T2 (de)
DK (1) DK0840604T3 (de)
ES (1) ES2183889T3 (de)
NO (1) NO952796D0 (de)
PT (1) PT840604E (de)
WO (1) WO1997003663A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058120A1 (en) * 1998-05-08 1999-11-18 Rolf Berge USE OF NON-β-OXIDIZABLE FATTY ACID ANALOGUES FOR TREATMENT OF SYNDROME-X CONDITIONS
AU784116B2 (en) * 1999-09-17 2006-02-09 Peplin Biolipids Pty Ltd Anti-cancer nitro- and thia-fatty acids
AUPQ291499A0 (en) * 1999-09-17 1999-10-07 Women's And Children's Hospital Adelaide Novel nitro and sulphur containing compounds
NO328803B1 (no) 2000-03-03 2010-05-18 Thia Medica Nye fettsyreanaloger
NO20003591L (no) * 2000-07-13 2002-01-14 Thia Medica As Fettsyreanaloger for behandling av kreft
NO20006008L (no) * 2000-11-28 2002-05-29 Thia Medica As Fettsyreanaloger for behandling av inflammatoriske og autoimmune sykdommer
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7314953B2 (en) * 2001-03-27 2008-01-01 Errant Gene Therapeutics, Llc Treatment of lung cells with histone deacetylase inhibitors
US8026280B2 (en) 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US6495719B2 (en) 2001-03-27 2002-12-17 Circagen Pharmaceutical Histone deacetylase inhibitors
US7312247B2 (en) 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
FR2828487B1 (fr) 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
EP1511477A4 (de) * 2002-05-22 2008-04-09 Errant Gene Therapeutics Llc Histondeacetylase-hemmer auf basis von alpha-ketoepoxid-verbindungen
NZ537762A (en) 2002-06-20 2007-02-23 Thia Medica As Sulfur-containing phospholipid derivatives
FR2850650B1 (fr) * 2003-01-31 2005-03-25 Genfit S A Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures
FR2850869B1 (fr) * 2003-02-12 2005-03-25 Genfit S A Utilisations d'aminopropanediols acyles et de leurs analogues azotes et sulfures
US20090215895A1 (en) * 2004-01-30 2009-08-27 Peplin Biolipids Pty Ltd Therapeutic and carrier molecules
RU2388490C2 (ru) * 2004-07-19 2010-05-10 Тиа Медика Ас Композиция, содержащая растительный или рыбий жир, и соединения, содержащие неокисляющиеся структурные элементы жирных кислот
JP2008506774A (ja) * 2004-07-19 2008-03-06 ティア メディカ アクスイェ セルスカプ タンパク質材料と非酸化性脂肪酸体を含む組成物
US20060160902A1 (en) * 2004-11-08 2006-07-20 Wiech Norbert L Histone deacetylase inhibitors
CA2904898C (en) 2013-03-11 2019-10-15 Jan Remmereit Lipid compositions containing bioactive fatty acids
AU2014229506B2 (en) 2013-03-11 2017-04-13 Nobesita As Natural lipids containing non-oxidizable fatty acids
CN105498622B (zh) * 2015-12-10 2017-10-17 江南大学 一种含硒表面活性剂及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2208533A1 (de) * 1972-02-23 1973-09-27 Kolmar Laboratories Neue alkylthioaether
GB8813012D0 (en) * 1988-06-02 1988-07-06 Norsk Hydro As Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals

Also Published As

Publication number Publication date
JPH11514339A (ja) 1999-12-07
DE69528291D1 (de) 2002-10-24
JP3553966B2 (ja) 2004-08-11
NO952796D0 (no) 1995-07-14
AU4272696A (en) 1997-02-18
DK0840604T3 (da) 2002-12-30
DE69528291T2 (de) 2003-05-08
EP0840604B1 (de) 2002-09-18
PT840604E (pt) 2003-01-31
US6046237A (en) 2000-04-04
KR19990028993A (ko) 1999-04-15
ES2183889T3 (es) 2003-04-01
EP1232750A1 (de) 2002-08-21
KR100394986B1 (ko) 2004-01-24
WO1997003663A1 (en) 1997-02-06
EP0840604A1 (de) 1998-05-13
CA2226871A1 (en) 1997-02-06
AU6124300A (en) 2000-11-30
AU734431B2 (en) 2001-06-14
EP1232749A1 (de) 2002-08-21

Similar Documents

Publication Publication Date Title
ATE224188T1 (de) Nicht-beta oxidierbare fettsäureanaloge,deren verwendung als therapeutisch wirksame medikamente sowie deren herstellung
EP0345038A3 (de) Nicht-beta-oxidierbare Fettsäure-Analoge, die die Blutkonzentration von Cholesterin und Triglyceriden bei Säugetieren senken
ES2131207T3 (es) Derivados de amidas del acido valproico y 2-valproenoico y su uso como anticonvulsivos.
ATE1814T1 (de) 9-hydroxyalkylpurine, verfahren zu ihrer herstellung und 9-hydroxyalkylpurine als aktive mittel enthaltende therapeutische zusammensetzung.
AU3559193A (en) New 3',5'-di-tert-butyl-4'-hydroxy flavones, process for the preparation thereof and pharmaceutical compositions containing them
EP0712843A4 (de) Vitamin d3 derivat und verfahren zu dessen herstellung
MX9606665A (es) Derivados de acido 3-amino-2-mercaptobenzoico y procesos para su preparacion.
DE3874440D1 (de) Zusammensetzung zur herstellung von antithrombotischen medizinischen erzeugnissen.
ES2004141A6 (es) Un procedimiento de preparacion de nuevas 1,4-dihidropiridinas
ES8306745A1 (es) Un procedimiento para la preparacion de nuevos derivados de 2-piperazino pirimioina.
AU5704586A (en) Hexenoic acids
KR920012008A (ko) 페닐알킬아미노알킬 화합물과 이들의 제법 및 이 화합물들을 포함하는 약물
ATE144507T1 (de) Dithian substituierte retinoide, ihre verwendung, verfahren zu ihrer herstellung, diese enthaltende kosmetische und pharmazeutische zusammensetzungen und ihre therapeutische verwendung
SE9701912D0 (sv) Pharmaceutical composition and use thereof
ATE37393T1 (de) Mikroorganismusstamm chromobacterium violaceum, aus diesem hergestellte pharmazeutisch aktive verbindungen, ein verfahren zu deren herstellung und deren verwendung als medikamente.
KR950702566A (ko) 사슬형 아미딘기를 포함하는 디포스폰산 유도체, 그것의 제조방법 및 그것을 포함하는 의약 조성물(novel acyclic amidine-group-containing diphosphonic acid derivatives, process for producing them and medicaments containing these compounds)
ATE27459T1 (de) 17-alpha-pregn-4-ene-3-oxo-21-carbonsauereester, verfahren zu deren herstellung und verwendung in arzneimitteln.
KR940005279A (ko) 아미딘을 함유하는 약제학적 조성물 및 아미딘
DE69818060D1 (de) Polyhydroxyalkylpyrazine derivate, deren herstellung,diese enthaltende arzneimitteln
DE3689807D1 (de) Imidazolderivate, deren Herstellung und therapeutische Verwendung.
GR3036868T3 (en) Amino alcohol derivatives, methods of producing said derivatives and medicaments containing them
DE3683073D1 (de) 3-oxo-2-azabicyclohexan-derivate, verfahren zu ihrer herstellung und verwendung dieser derivate als zwischenverbindungen fuer antibakterielle wirkstoffe.
ATE186907T1 (de) Optisch aktives 1-phenylpyrrolidonderivat und dessen herstellung
JPS5533460A (en) Cis-3-hexene derivative
IT1250625B (it) Derivati dell'eseridina utili per il trattamento delle malattie associaate a disordini colinergici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0840604

Country of ref document: EP

REN Ceased due to non-payment of the annual fee