ES2183889T3 - Analogos de acidos grasos no beta-oxidables, sus usos como medicamentos terapeuticamente activos y su preparacion. - Google Patents

Analogos de acidos grasos no beta-oxidables, sus usos como medicamentos terapeuticamente activos y su preparacion.

Info

Publication number
ES2183889T3
ES2183889T3 ES95941241T ES95941241T ES2183889T3 ES 2183889 T3 ES2183889 T3 ES 2183889T3 ES 95941241 T ES95941241 T ES 95941241T ES 95941241 T ES95941241 T ES 95941241T ES 2183889 T3 ES2183889 T3 ES 2183889T3
Authority
ES
Spain
Prior art keywords
oxidable
analogs
beta
preparation
fatty acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95941241T
Other languages
English (en)
Inventor
Rolf Berge
Jon Songstad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2183889T3 publication Critical patent/ES2183889T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTAN COMPUESTOS CUYA FORMULA GENERAL ES (I): ALQUILO X SATURADO O INSATURADO DE 8 TA UN ATOMO DE AZUFRE O UN ATOMO DE SELENIO Y R ES HIDROGENO O C SUB,1} ERLIPEMICOS (ENFERMEDAD ARTERIOESCLEROTICA), ARTERIOPATIA CORONARIA Y PARA REDUCIR LA CONCENTRACION SANGUINEA DE LIPIDOS EN LOS MAMIFEROS, PARA INHIBIR LA MODIFICACION OXIDATIVA DE LAS LDL Y PARA REDUCIR LA PROLIFERACION DE CELULAS CANCEROSAS. TAMBIEN SE PRESENTAN LOS METODOS DE PREPARACION DE LOS COMPUESTOS.
ES95941241T 1995-07-14 1995-10-25 Analogos de acidos grasos no beta-oxidables, sus usos como medicamentos terapeuticamente activos y su preparacion. Expired - Lifetime ES2183889T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO952796A NO952796D0 (no) 1995-07-14 1995-07-14 Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater

Publications (1)

Publication Number Publication Date
ES2183889T3 true ES2183889T3 (es) 2003-04-01

Family

ID=19898394

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95941241T Expired - Lifetime ES2183889T3 (es) 1995-07-14 1995-10-25 Analogos de acidos grasos no beta-oxidables, sus usos como medicamentos terapeuticamente activos y su preparacion.

Country Status (13)

Country Link
US (1) US6046237A (es)
EP (3) EP1232749A1 (es)
JP (1) JP3553966B2 (es)
KR (1) KR100394986B1 (es)
AT (1) ATE224188T1 (es)
AU (2) AU4272696A (es)
CA (1) CA2226871A1 (es)
DE (1) DE69528291T2 (es)
DK (1) DK0840604T3 (es)
ES (1) ES2183889T3 (es)
NO (1) NO952796D0 (es)
PT (1) PT840604E (es)
WO (1) WO1997003663A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058120A1 (en) * 1998-05-08 1999-11-18 Rolf Berge USE OF NON-β-OXIDIZABLE FATTY ACID ANALOGUES FOR TREATMENT OF SYNDROME-X CONDITIONS
AU784116B2 (en) * 1999-09-17 2006-02-09 Peplin Biolipids Pty Ltd Anti-cancer nitro- and thia-fatty acids
AUPQ291499A0 (en) * 1999-09-17 1999-10-07 Women's And Children's Hospital Adelaide Novel nitro and sulphur containing compounds
NO328803B1 (no) * 2000-03-03 2010-05-18 Thia Medica Nye fettsyreanaloger
NO20003591L (no) * 2000-07-13 2002-01-14 Thia Medica As Fettsyreanaloger for behandling av kreft
NO20006008L (no) * 2000-11-28 2002-05-29 Thia Medica As Fettsyreanaloger for behandling av inflammatoriske og autoimmune sykdommer
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US6495719B2 (en) * 2001-03-27 2002-12-17 Circagen Pharmaceutical Histone deacetylase inhibitors
US8026280B2 (en) 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7312247B2 (en) 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
FR2828487B1 (fr) 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
WO2003099272A1 (en) * 2002-05-22 2003-12-04 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
WO2004000854A1 (en) * 2002-06-20 2003-12-31 Ic Vec Limited Sulfur-containing phospholipid derivatives
WO2004046104A2 (en) * 2002-11-20 2004-06-03 Errant Gene Therapeutics, Llc Treatment of lung cells with histone deacetylase inhibitors
FR2850650B1 (fr) * 2003-01-31 2005-03-25 Genfit S A Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures
FR2850869B1 (fr) * 2003-02-12 2005-03-25 Genfit S A Utilisations d'aminopropanediols acyles et de leurs analogues azotes et sulfures
CA2554735A1 (en) * 2004-01-30 2005-08-11 Peplin Biolipids Pty Ltd Therapeutic and carrier molecules
RU2388490C2 (ru) * 2004-07-19 2010-05-10 Тиа Медика Ас Композиция, содержащая растительный или рыбий жир, и соединения, содержащие неокисляющиеся структурные элементы жирных кислот
NZ553260A (en) * 2004-07-19 2010-12-24 Thia Medica As Composition comprising protein material and non-oxidizable fatty acid entities
CA2587013A1 (en) * 2004-11-08 2006-05-18 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
CA2904898C (en) 2013-03-11 2019-10-15 Jan Remmereit Lipid compositions containing bioactive fatty acids
AU2014229506B2 (en) 2013-03-11 2017-04-13 Nobesita As Natural lipids containing non-oxidizable fatty acids
CN105498622B (zh) * 2015-12-10 2017-10-17 江南大学 一种含硒表面活性剂及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2208533A1 (de) * 1972-02-23 1973-09-27 Kolmar Laboratories Neue alkylthioaether
GB8813012D0 (en) * 1988-06-02 1988-07-06 Norsk Hydro As Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals

Also Published As

Publication number Publication date
DE69528291D1 (de) 2002-10-24
ATE224188T1 (de) 2002-10-15
AU4272696A (en) 1997-02-18
NO952796D0 (no) 1995-07-14
EP1232750A1 (en) 2002-08-21
EP0840604A1 (en) 1998-05-13
JP3553966B2 (ja) 2004-08-11
AU734431B2 (en) 2001-06-14
AU6124300A (en) 2000-11-30
PT840604E (pt) 2003-01-31
EP1232749A1 (en) 2002-08-21
EP0840604B1 (en) 2002-09-18
DK0840604T3 (da) 2002-12-30
WO1997003663A1 (en) 1997-02-06
KR19990028993A (ko) 1999-04-15
CA2226871A1 (en) 1997-02-06
US6046237A (en) 2000-04-04
DE69528291T2 (de) 2003-05-08
KR100394986B1 (ko) 2004-01-24
JPH11514339A (ja) 1999-12-07

Similar Documents

Publication Publication Date Title
ES2183889T3 (es) Analogos de acidos grasos no beta-oxidables, sus usos como medicamentos terapeuticamente activos y su preparacion.
UY23910A1 (es) Procedimiento para la preparacion de 5- derivados sustitutivos del acido micofenolico
ES2036593T3 (es) Composiciones que utilizan medicamentos antiinflamatorios no esteroidales encapsulados en liposomas.
ES2169023T3 (es) Nueva 1alfa-hidroxi vitaminada d4 y nuevos intermedios y analogos.
BR9713412A (pt) Composição cosmética adequada para aplicação tópica à pele ou cabelo e processo de tratamento cosmético
ES2185772T3 (es) Derivados de 1,3-propano-diol como compuestos bioactivos.
ES8103015A1 (es) Procedimiento para preparar derivados de polioles
ES2059749T3 (es) Compuestos analogos a los acidos grasos no oxidables en la posicion beta con efecto para reducir la concentracion de colesterol y trigliceridos en sangre de mamiferos.
SE8102194L (sv) Terapeutiskt aktiv organisk forening och farmaceutisk beredning innehallande denna
NO152446C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 9-substituerte hypoxantinderivater
DE69526353D1 (de) Immunologische aktivität der rhamnolipide
DK0534445T3 (da) Fremgangsmåde til fremstilling af et lægemiddel til oral eller topisk administrering ved behandling af Leishmaniasis
ES2062443T3 (es) Nuevos derivados peptidicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2091249T3 (es) Analogos de iludina utilizables como agentes antitumorales.
FR2354338A1 (fr) Acides n-phosphonomethylene-monoaminoalcane-mono- et polyphosphoniques et acides n-phosphonomethylene-diaminoalcane-polyphosphoniques, et leur preparation
FR2381753A1 (fr) Nouveaux derives de la pyrrolidine, leur procede de preparation et leur application en therapeutique
FR2445834A1 (fr) Derives heterobicycliques de l'acide 7-acylamido-3-cephem-4-carboxylique insature, procedes de preparation de ceux-ci et utilisation en therapeutique
FR2358406A1 (fr) Derives d'acides 5-aroyl-1,2-dihydro-3h-pyrrolo (1,2-a)pyrrole-1-carboxyliques, leur obtention et leur application a titre de medicament
ES2054650T3 (es) Fenilacetonitrilos basicamente substituidos, su obtencion y medicamentos que los contienen.
ES8707535A1 (es) Un procedimiento para preparar nuevos derivados de carbapenem
IL58064A0 (en) Fluorinated polyene compounds their preparation and pharmaceutical compositions containing them
FR2398712A1 (fr) Derives du norbornane et du norbornene et leur utilisation en parfumerie comme substituants de l'essence de bois de santal
NO162469C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive purin-derivater.
FR2378518A1 (fr) Nouveaux medicaments a base de derives de tetrahydrodibenzopyranne
FR2392966A1 (fr) Nouveaux acides uree-bis(naphtalene-sulfoniques et naphtalene-carboxyliques), leurs sels pharmaceutiquement acceptables, et leur utilisation therapeutique