ATE224447T1 - Kainat bindende, menschliche rezeptoren des zentralnervensystems (zns), von der eaa4 (excitatory amino acid) familie - Google Patents

Kainat bindende, menschliche rezeptoren des zentralnervensystems (zns), von der eaa4 (excitatory amino acid) familie

Info

Publication number: ATE224447T1
Authority: AT; Austria
Prior art keywords: receptors; family; excitatory amino; eaa4; cns
Prior art date: 1992-06-24

Application number

AT93304961T

Other languages

English (en)

Inventor

Rajender Kamboj

Candace Elliott

Stephen L Nutt

Original Assignee

Allelix Biopharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-24

Filing date

1993-06-24

Publication date

2002-10-15

1993-06-24 Application filed by Allelix Biopharma filed Critical Allelix Biopharma

2002-10-15 Application granted granted Critical

2002-10-15 Publication of ATE224447T1 publication Critical patent/ATE224447T1/de

Links

230000002461 excitatory amino acid Effects 0.000 title abstract 4
239000003257 excitatory amino acid Substances 0.000 title abstract 4
VLSMHEGGTFMBBZ-OOZYFLPDSA-M Kainate Chemical compound CC(=C)[C@H]1C[NH2+][C@H](C([O-])=O)[C@H]1CC([O-])=O VLSMHEGGTFMBBZ-OOZYFLPDSA-M 0.000 title abstract 2
210000003169 central nervous system Anatomy 0.000 title 2
102000005962 receptors Human genes 0.000 abstract 6
108020003175 receptors Proteins 0.000 abstract 6
239000012528 membrane Substances 0.000 abstract 2
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
230000000638 stimulation Effects 0.000 abstract 1
230000005062 synaptic transmission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Neurology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Cell Biology (AREA)
Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Magnetic Resonance Imaging Apparatus (AREA)
Fluid-Damping Devices (AREA)
Investigating Or Analysing Biological Materials (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT93304961T 1992-06-24 1993-06-24 Kainat bindende, menschliche rezeptoren des zentralnervensystems (zns), von der eaa4 (excitatory amino acid) familie ATE224447T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/903,456 US5574144A (en)	1992-06-24	1992-06-24	Kainate-binding, human CNS receptors of the EAA4 family

Publications (1)

Publication Number	Publication Date
ATE224447T1 true ATE224447T1 (de)	2002-10-15

Family

ID=25417534

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93304961T ATE224447T1 (de)	1992-06-24	1993-06-24	Kainat bindende, menschliche rezeptoren des zentralnervensystems (zns), von der eaa4 (excitatory amino acid) familie

Country Status (10)

Country	Link
US (3)	US5574144A (de)
EP (1)	EP0578409B1 (de)
JP (1)	JPH06189767A (de)
AT (1)	ATE224447T1 (de)
CA (1)	CA2099072A1 (de)
DE (1)	DE69332299T2 (de)
DK (1)	DK0578409T3 (de)
ES (1)	ES2183809T3 (de)
MX (1)	MX9303769A (de)
PT (1)	PT578409E (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69434333T2 (de) *	1993-12-23	2006-03-09	Nps Allelix Corp., Mississauga	Methoden unter verwendung von eaa3 oder eaa4 rezeptoren
GB2316616A (en) *	1996-09-02	1998-03-04	Lilly Industries Ltd	Modulation of GluR5 receptors in the hippocampus to treat psychiatric disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991006648A1 (en) *	1989-10-27	1991-05-16	The Salk Institute For Biological Studies	Glutamate receptor compositions and methods
PT529994E (pt) *	1991-08-26	2000-10-31	Nps Allelix Corp	Receptor de ka-1 humano um receptor de cainato de elevada afinidade da familia eaa1 (aminoacido excitatorio)
DE69230872T2 (de) *	1991-08-27	2000-10-26	Allelix Biopharmaceuticals Inc., Mississauga	Menschlicher KA-2-Rezeptor, Rezeptor aus der EAA2-Familie (Excitatory Amino Acid) mit hoher Affinität für Kainat

1992
- 1992-06-24 US US07/903,456 patent/US5574144A/en not_active Expired - Lifetime
1993
- 1993-06-23 CA CA002099072A patent/CA2099072A1/en not_active Abandoned
- 1993-06-23 MX MX9303769A patent/MX9303769A/es unknown
- 1993-06-24 DE DE69332299T patent/DE69332299T2/de not_active Expired - Fee Related
- 1993-06-24 AT AT93304961T patent/ATE224447T1/de not_active IP Right Cessation
- 1993-06-24 PT PT93304961T patent/PT578409E/pt unknown
- 1993-06-24 DK DK93304961T patent/DK0578409T3/da active
- 1993-06-24 JP JP5177327A patent/JPH06189767A/ja active Pending
- 1993-06-24 EP EP93304961A patent/EP0578409B1/de not_active Expired - Lifetime
- 1993-06-24 ES ES93304961T patent/ES2183809T3/es not_active Expired - Lifetime
1994
- 1994-05-25 US US08/249,241 patent/US6376200B1/en not_active Expired - Fee Related
2002
- 2002-04-22 US US10/126,617 patent/US20020168723A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE69332299T2 (de)	2003-05-08
CA2099072A1 (en)	1993-12-25
PT578409E (pt)	2003-02-28
US5574144A (en)	1996-11-12
JPH06189767A (ja)	1994-07-12
US6376200B1 (en)	2002-04-23
EP0578409A2 (de)	1994-01-12
US20020168723A1 (en)	2002-11-14
ES2183809T3 (es)	2003-04-01
EP0578409A3 (de)	1994-11-23
EP0578409B1 (de)	2002-09-18
DE69332299D1 (de)	2002-10-24
DK0578409T3 (da)	2003-01-27
MX9303769A (es)	1994-05-31

Legal Events

Date	Code	Title	Description
2003-02-15	UEP	Publication of translation of european patent specification	Ref document number: 0578409 Country of ref document: EP
2004-11-15	EEFA	Change of the company name
2010-03-15	EEIH	Change in the person of patent owner
2011-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ZA90944B (en)	1991-10-30	Compounds which are antagonists of excitatory amino acid receptors
MY131442A (en)	2007-08-30	Excitatory amino acid receptor antagonists
ATE283916T1 (de)	2004-12-15	Menschliche metabotropische glutamatrezeptor untertype hmglur7 und verwandte dns-verbindungen
IL122980A0 (en)	1998-08-16	Traf inhibitors
ES2055036T3 (es)	1994-08-16	Antagonistas tetrazolicos de receptores de aminoacidos excitadores.
ATE184051T1 (de)	1999-09-15	Kainat bindende menschliche cns-rezeptoren aus der eaa3-familie
GR3033881T3 (en)	2000-11-30	Human KA-1 receptor, a kainate high affinity receptor of the EAA1 (Excitatory Amino Acid) family.
DE69332299D1 (de)	2002-10-24	Kainat bindende, menschliche Rezeptoren des Zentralnervensystems (ZNS), von der EAA4 (Excitatory Amino Acid) Familie
GR3033880T3 (en)	2000-11-30	Human KA-2 receptor, a kainate high affinity receptor of the EAA2 (Excitatory Amino Acid) family.
ATE156188T1 (de)	1997-08-15	Kainatebindende, menschliche cns-rezeptoren der eaa5-familie
DE69328060D1 (de)	2000-04-20	Angiotensin-II Typ-1 Rezeptor und dessen Herstellung
DK210288A (da)	1988-04-18	Overproduktion af exocelllulaere proteiner
Kamboj et al.	1997	Kainate-binding, human CNS receptors of the EAA2 family