ES2183809T3 - Receptores del snc (sistema nervioso central) humanos, que se unen a cainato, de la familia de eaa4 (aminoacidos excitadores). - Google Patents

Receptores del snc (sistema nervioso central) humanos, que se unen a cainato, de la familia de eaa4 (aminoacidos excitadores).

Info

Publication number: ES2183809T3
Authority: ES; Spain
Prior art keywords: receptors; family; amino acids; cainato; eaa4
Prior art date: 1992-06-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES93304961T

Other languages

English (en)

Spanish (es)

Inventor

Rajender Kamboj

Candace Elliott

Stephen L Nutt

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

NPS Allelix Corp Canada

Original Assignee

NPS Allelix Corp Canada

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-24

Filing date

1993-06-24

Publication date

2003-04-01

1993-06-24 Application filed by NPS Allelix Corp Canada filed Critical NPS Allelix Corp Canada

2003-04-01 Application granted granted Critical

2003-04-01 Publication of ES2183809T3 publication Critical patent/ES2183809T3/es

2013-06-24 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

102000005962 receptors Human genes 0.000 title abstract 7
108020003175 receptors Proteins 0.000 title abstract 7
102100022758 Glutamate receptor ionotropic, kainate 2 Human genes 0.000 title 1
101000903346 Homo sapiens Glutamate receptor ionotropic, kainate 2 Proteins 0.000 title 1
150000001413 amino acids Chemical class 0.000 title 1
210000003169 central nervous system Anatomy 0.000 title 1
239000003257 excitatory amino acid Substances 0.000 abstract 2
230000002461 excitatory amino acid Effects 0.000 abstract 2
239000012528 membrane Substances 0.000 abstract 2
VLSMHEGGTFMBBZ-OOZYFLPDSA-M Kainate Chemical compound CC(=C)[C@H]1C[NH2+][C@H](C([O-])=O)[C@H]1CC([O-])=O VLSMHEGGTFMBBZ-OOZYFLPDSA-M 0.000 abstract 1
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
230000000638 stimulation Effects 0.000 abstract 1
230000005062 synaptic transmission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Neurology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Cell Biology (AREA)
Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Investigating Or Analysing Biological Materials (AREA)
Magnetic Resonance Imaging Apparatus (AREA)
Fluid-Damping Devices (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

ES93304961T 1992-06-24 1993-06-24 Receptores del snc (sistema nervioso central) humanos, que se unen a cainato, de la familia de eaa4 (aminoacidos excitadores). Expired - Lifetime ES2183809T3 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/903,456 US5574144A (en)	1992-06-24	1992-06-24	Kainate-binding, human CNS receptors of the EAA4 family

Publications (1)

Publication Number	Publication Date
ES2183809T3 true ES2183809T3 (es)	2003-04-01

Family

ID=25417534

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES93304961T Expired - Lifetime ES2183809T3 (es)	1992-06-24	1993-06-24	Receptores del snc (sistema nervioso central) humanos, que se unen a cainato, de la familia de eaa4 (aminoacidos excitadores).

Country Status (10)

Country	Link
US (3)	US5574144A (de)
EP (1)	EP0578409B1 (de)
JP (1)	JPH06189767A (de)
AT (1)	ATE224447T1 (de)
CA (1)	CA2099072A1 (de)
DE (1)	DE69332299T2 (de)
DK (1)	DK0578409T3 (de)
ES (1)	ES2183809T3 (de)
MX (1)	MX9303769A (de)
PT (1)	PT578409E (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2179208C (en) *	1993-12-23	2003-05-27	Rajender Kamboj	Human cns receptor polynucleotides
GB2316616A (en) *	1996-09-02	1998-03-04	Lilly Industries Ltd	Modulation of GluR5 receptors in the hippocampus to treat psychiatric disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE265528T1 (de) *	1989-10-27	2004-05-15	Salk Inst For Biological Studi	Rezeptorverbindungen von glutamin und herstellung
ATE191747T1 (de) *	1991-08-26	2000-04-15	Allelix Biopharma	Menschlicher ka-1 rezeptor, rezeptor aus der eaa1-familie (excitatory amino acid) mit hoher affinität für kainat
ES2148166T3 (es) *	1991-08-27	2000-10-16	Nps Allelix Corp	Receptor de ka-2 humano, un receptor de alta afinidad de cainato de la familia eaa2 (aminoacidos excitaddores).

1992
- 1992-06-24 US US07/903,456 patent/US5574144A/en not_active Expired - Lifetime
1993
- 1993-06-23 CA CA002099072A patent/CA2099072A1/en not_active Abandoned
- 1993-06-23 MX MX9303769A patent/MX9303769A/es unknown
- 1993-06-24 DK DK93304961T patent/DK0578409T3/da active
- 1993-06-24 ES ES93304961T patent/ES2183809T3/es not_active Expired - Lifetime
- 1993-06-24 JP JP5177327A patent/JPH06189767A/ja active Pending
- 1993-06-24 EP EP93304961A patent/EP0578409B1/de not_active Expired - Lifetime
- 1993-06-24 DE DE69332299T patent/DE69332299T2/de not_active Expired - Fee Related
- 1993-06-24 AT AT93304961T patent/ATE224447T1/de not_active IP Right Cessation
- 1993-06-24 PT PT93304961T patent/PT578409E/pt unknown
1994
- 1994-05-25 US US08/249,241 patent/US6376200B1/en not_active Expired - Fee Related
2002
- 2002-04-22 US US10/126,617 patent/US20020168723A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DK0578409T3 (da)	2003-01-27
ATE224447T1 (de)	2002-10-15
DE69332299D1 (de)	2002-10-24
US20020168723A1 (en)	2002-11-14
MX9303769A (es)	1994-05-31
EP0578409B1 (de)	2002-09-18
US6376200B1 (en)	2002-04-23
DE69332299T2 (de)	2003-05-08
US5574144A (en)	1996-11-12
JPH06189767A (ja)	1994-07-12
CA2099072A1 (en)	1993-12-25
EP0578409A2 (de)	1994-01-12
EP0578409A3 (de)	1994-11-23
PT578409E (pt)	2003-02-28

Publication	Publication Date	Title
ZA90944B (en)	1991-10-30	Compounds which are antagonists of excitatory amino acid receptors
ATE522610T1 (de)	2011-09-15	Menschliche, metabotrope glutamatrezeptor- subtypen (hmr6) und verwandte dns-verbindungen
EE9900492A (et)	2000-06-15	II tüüpi TGF-ß retseptori/immunoglobuliini konstantse piirkonna hübriidvalgud
ES2055036T3 (es)	1994-08-16	Antagonistas tetrazolicos de receptores de aminoacidos excitadores.
DK0617123T3 (da)	1999-12-13	Kainatbindende, humane CNS-receptorer af EAA3-familien
MX9307840A (es)	1994-07-29	Polinucleotido aislado, celula para producir un receptor de aminoacido excitador y proceso para obtener una fuente substancialmente homogenea de un receptor de aminoacido excitador.
DK0529994T3 (da)	2001-04-30	Human KA-1-receptor, en kaniat højaffinitetsreceptor af EAA1-familien (excitatoriske aminosyrer)
PT578409E (pt)	2003-02-28	Receptores humanos do cns (sistema nervoso central) da familia eaa4 (aminoacidos excitadores) que ligam cainato
DK0529995T3 (da)	2000-07-03	Human KA-receptor, receptor af EAA2-familien (Excitatorisk aminosyre) med høj affinitet for kainat
ES2105122T3 (es)	1997-10-16	Receptores de fijacion de kainato de la familia aae5 del snc humano.
EP0316748A3 (en)	1990-08-29	Process for the selective cleavage of fusion proteins
DE69011702D1 (de)	1994-09-29	Derivate von Aminocarboxylsäure.