ATE224867T1 - Verfahren zur herstellung von kontrastmitteln - Google Patents

Verfahren zur herstellung von kontrastmitteln

Info

Publication number: ATE224867T1
Authority: AT; Austria
Prior art keywords: contrast agents; producing contrast; lanthanide; producing; metallation
Prior art date: 1997-04-18

Application number

AT98914995T

Other languages

English (en)

Inventor

Ole Magne Homestad

Espen Myrbraten

Original Assignee

Amersham Health As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-18

Filing date

1998-04-07

Publication date

2002-10-15

1998-04-07 Application filed by Amersham Health As filed Critical Amersham Health As

2002-10-15 Application granted granted Critical

2002-10-15 Publication of ATE224867T1 publication Critical patent/ATE224867T1/de

Links

239000002872 contrast media Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 abstract 3
229910052747 lanthanoid Inorganic materials 0.000 abstract 2
150000002602 lanthanoids Chemical class 0.000 abstract 2
RZESKRXOCXWCFX-UHFFFAOYSA-N 2-[bis[2-[carboxymethyl-[2-(methylamino)-2-oxoethyl]amino]ethyl]amino]acetic acid Chemical compound CNC(=O)CN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC(=O)NC RZESKRXOCXWCFX-UHFFFAOYSA-N 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
239000008139 complexing agent Substances 0.000 abstract 1
229910000311 lanthanide oxide Inorganic materials 0.000 abstract 1
238000006263 metalation reaction Methods 0.000 abstract 1
235000006408 oxalic acid Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Manufacturing Of Micro-Capsules (AREA)
Length Measuring Devices By Optical Means (AREA)

AT98914995T 1997-04-18 1998-04-07 Verfahren zur herstellung von kontrastmitteln ATE224867T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9707880.2A GB9707880D0 (en)	1997-04-18	1997-04-18	Contrast agent preparation
US4440997P	1997-04-29	1997-04-29
PCT/GB1998/001019 WO1998047856A1 (en)	1997-04-18	1998-04-07	Contrast agent preparation

Publications (1)

Publication Number	Publication Date
ATE224867T1 true ATE224867T1 (de)	2002-10-15

Family

ID=26311410

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98914995T ATE224867T1 (de)	1997-04-18	1998-04-07	Verfahren zur herstellung von kontrastmitteln

Country Status (18)

Country	Link
US (1)	US6191262B1 (de)
EP (1)	EP0975580B1 (de)
JP (1)	JP4035625B2 (de)
CN (1)	CN100352802C (de)
AT (1)	ATE224867T1 (de)
AU (1)	AU745970B2 (de)
BR (1)	BR9808924A (de)
CA (1)	CA2287245A1 (de)
CZ (1)	CZ296233B6 (de)
DE (1)	DE69808265T2 (de)
ES (1)	ES2187018T3 (de)
GB (1)	GB9707880D0 (de)
HU (1)	HUP0001861A2 (de)
IL (1)	IL132433A0 (de)
NO (1)	NO320618B1 (de)
NZ (1)	NZ500061A (de)
PL (1)	PL336208A1 (de)
WO (1)	WO1998047856A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2794032B1 (fr) *	1999-05-27	2002-06-14	Univ Claude Bernard Lyon	Procede pour separer en milieu aqueux des lanthanides et/ou des actinides par complexation-nanofiltration, et nouveaux complexants mis en oeuvre dans ce procede
CN1321122C (zh) *	2005-02-03	2007-06-13	华东师范大学	一种水热合成钆－二乙三胺五乙酸的方法
EP2338874A1 (de) *	2009-12-16	2011-06-29	Bracco Imaging S.p.A	Verfahren zur Herstellung von chelatierten Verbindungen
CN106008254B (zh) *	2016-05-27	2018-08-21	南京正大天晴制药有限公司	一种卡地酰胺钠的精制工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4647447A (en) *	1981-07-24	1987-03-03	Schering Aktiengesellschaft	Diagnostic media
FR2669028B1 (fr) *	1990-11-13	1992-12-31	Rhone Poulenc Chimie	Procede de fabrication d'oxalates doubles de terres rares et d'ammonium et leurs utilisations pour la fabrication d'oxydes de terres rares.
FR2674256B1 (fr) *	1991-03-21	1994-07-29	Commissariat Energie Atomique	Procede pour separer le fer et/ou le zirconium des actinides et/ou des lanthanides presents dans une solution aqueuse acide au moyen d'un propanediamide.

1997
- 1997-04-18 GB GBGB9707880.2A patent/GB9707880D0/en active Pending
1998
- 1998-04-07 WO PCT/GB1998/001019 patent/WO1998047856A1/en not_active Ceased
- 1998-04-07 EP EP98914995A patent/EP0975580B1/de not_active Expired - Lifetime
- 1998-04-07 CA CA002287245A patent/CA2287245A1/en not_active Abandoned
- 1998-04-07 BR BR9808924-2A patent/BR9808924A/pt unknown
- 1998-04-07 AT AT98914995T patent/ATE224867T1/de not_active IP Right Cessation
- 1998-04-07 IL IL13243398A patent/IL132433A0/xx unknown
- 1998-04-07 AU AU69287/98A patent/AU745970B2/en not_active Ceased
- 1998-04-07 CN CNB988041316A patent/CN100352802C/zh not_active Expired - Lifetime
- 1998-04-07 HU HU0001861A patent/HUP0001861A2/hu unknown
- 1998-04-07 DE DE69808265T patent/DE69808265T2/de not_active Expired - Lifetime
- 1998-04-07 NZ NZ500061A patent/NZ500061A/en unknown
- 1998-04-07 ES ES98914995T patent/ES2187018T3/es not_active Expired - Lifetime
- 1998-04-07 CZ CZ0368899A patent/CZ296233B6/cs unknown
- 1998-04-07 PL PL98336208A patent/PL336208A1/xx unknown
- 1998-04-07 JP JP54526398A patent/JP4035625B2/ja not_active Expired - Lifetime
1999
- 1999-10-15 US US09/419,290 patent/US6191262B1/en not_active Expired - Lifetime
- 1999-10-15 NO NO19995058A patent/NO320618B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CZ368899A3 (cs)	2000-04-12
IL132433A0 (en)	2001-03-19
JP2001521545A (ja)	2001-11-06
GB9707880D0 (en)	1997-06-04
AU745970B2 (en)	2002-04-11
CN1252051A (zh)	2000-05-03
DE69808265T2 (de)	2003-07-31
CN100352802C (zh)	2007-12-05
WO1998047856A1 (en)	1998-10-29
US6191262B1 (en)	2001-02-20
EP0975580B1 (de)	2002-09-25
AU6928798A (en)	1998-11-13
PL336208A1 (en)	2000-06-05
HK1025313A1 (en)	2000-11-10
ES2187018T3 (es)	2003-05-16
BR9808924A (pt)	2000-08-01
NZ500061A (en)	2001-04-27
JP4035625B2 (ja)	2008-01-23
DE69808265D1 (de)	2002-10-31
CZ296233B6 (cs)	2006-02-15
EP0975580A1 (de)	2000-02-02
NO320618B1 (no)	2005-12-27
HUP0001861A2 (hu)	2000-09-28
NO995058L (no)	1999-10-15
NO995058D0 (no)	1999-10-15
CA2287245A1 (en)	1998-10-29

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Legal Events

Date	Code	Title	Description
2003-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties