ATE225345T1 - Auf serotonin-verwandte systeme wirkende piperidin-derivate - Google Patents

Auf serotonin-verwandte systeme wirkende piperidin-derivate

Info

Publication number
ATE225345T1
ATE225345T1 AT99305095T AT99305095T ATE225345T1 AT E225345 T1 ATE225345 T1 AT E225345T1 AT 99305095 T AT99305095 T AT 99305095T AT 99305095 T AT99305095 T AT 99305095T AT E225345 T1 ATE225345 T1 AT E225345T1
Authority
AT
Austria
Prior art keywords
serotonin
related systems
piperidine derivatives
derivatives acting
acting
Prior art date
Application number
AT99305095T
Other languages
English (en)
Inventor
Daniel Timothy Kohlman
Sidney Xi Liang
Yao-Chang Xu
Larry Wayne Hertel
David Taiwai Wong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE225345T1 publication Critical patent/ATE225345T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT99305095T 1998-06-30 1999-06-29 Auf serotonin-verwandte systeme wirkende piperidin-derivate ATE225345T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9124198P 1998-06-30 1998-06-30

Publications (1)

Publication Number Publication Date
ATE225345T1 true ATE225345T1 (de) 2002-10-15

Family

ID=22226762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99305095T ATE225345T1 (de) 1998-06-30 1999-06-29 Auf serotonin-verwandte systeme wirkende piperidin-derivate

Country Status (12)

Country Link
US (1) US6436964B1 (de)
EP (1) EP0982304B1 (de)
JP (1) JP2002519323A (de)
AR (1) AR019178A1 (de)
AT (1) ATE225345T1 (de)
AU (1) AU4726699A (de)
CA (1) CA2336117A1 (de)
CO (1) CO5080791A1 (de)
DE (1) DE69903239T2 (de)
ES (1) ES2181366T3 (de)
PE (1) PE20000763A1 (de)
WO (1) WO2000000198A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4727799A (en) 1998-06-30 2000-01-17 Eli Lilly And Company Azepine derivatives having effects on serotonin related systems
CZ20014548A3 (cs) 1999-06-29 2002-04-17 Eli Lilly And Company Příprava substituovaných piperidin-4-onů
AU5866500A (en) * 1999-06-29 2001-01-31 Eli Lilly And Company Preparation of 7-substituted benzothiophenes
ES2231229T3 (es) * 1999-07-29 2005-05-16 Eli Lilly And Company Benzotiofenos serotoninergicos.
US6881733B1 (en) 1999-07-29 2005-04-19 Eli Lilly And Company Serotonergic benzofurans
DE60006825T2 (de) * 1999-07-29 2004-08-12 Eli Lilly And Co., Indianapolis Serotonerge benzofurane
JP2003510321A (ja) * 1999-09-29 2003-03-18 イーライ・リリー・アンド・カンパニー セロトニン再取込み抑制薬としてのピペリジン誘導体
CA2386092A1 (en) 1999-09-29 2001-04-05 Yao-Chang Xu Piperidine derivatives
ITMI20021329A1 (it) * 2002-06-14 2003-12-15 Recordati Chem Pharm Nuove ossialchilammine sostituite
US20040058962A1 (en) * 2002-06-14 2004-03-25 Amedeo Leonardi Phenylalkylamines and pyridylalkylamines
AU2003268361A1 (en) * 2002-08-30 2004-03-19 Watson Pharmaceuticals, Inc. Drug delivery system for treating urinary incontinence
DK1587788T3 (da) 2002-09-17 2007-09-24 Hoffmann La Roche 2,7-substituerede indoler og anvendelsen deraf som 5-HT6-modulatorer
EP1542973B1 (de) 2002-09-17 2008-07-30 F. Hoffmann-La Roche Ag 2,4-substituierte indole und deren verwendung als 5-ht6 modulatoren
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
ES2528797T3 (es) 2006-08-21 2015-02-12 Genentech, Inc. Compuestos de aza-benzotiofenilo y métodos de uso
DE112015006213A5 (de) 2015-02-24 2017-11-16 MSO Meßtechnik und Ortung GmbH Verfahren zur Messung des Erntegutmassestroms am Feldhäcksler
NL1041393B1 (en) 2015-07-07 2017-01-30 Kessener B V Method and device providing a liquid display.
DE102016002899B4 (de) 2016-03-09 2020-03-12 Johannes Kraus Feuerraum mit verbessertem Ausbrand
DE202016005695U1 (de) 2016-09-12 2016-10-04 Jürgen Raudis Seifenabstandhalter zum Trocknen fester Seifen mit Seifenabtropfbehälter

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006524A1 (de) 1978-06-22 1980-01-09 Ciba-Geigy Ag Neue Tetrahydropyridin- und Piperidinderivate und deren Säureadditionssalze, Verfahren zu deren Herstellung und solche enthaltende pharmazeutische Zusammensetzungen
GB2056435A (en) 1979-06-26 1981-03-18 Ciba Geigy Ag Novel Tetrahydropyridine and Piperidine Substituted Benzofuranes and Related Compounds
FR2670491B1 (fr) * 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
IE914218A1 (en) * 1991-09-11 1993-03-24 Mcneilab Inc Novel 4-arylpiperazines and 4-arylpiperidines
FI950486A0 (fi) * 1992-08-05 1995-02-03 Wyeth John & Brother Ltd Amidijohdannaiset
DK148392D0 (da) 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
GB9300195D0 (en) 1993-01-06 1993-03-03 Wyeth John & Brother Ltd Piperazine derivatives
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
JP3989554B2 (ja) * 1996-03-29 2007-10-10 デユフアー・インターナシヨナル・リサーチ・ベー・ブイ ピペラジンおよびピペリジン化合物
KR100545329B1 (ko) 1997-07-25 2006-01-24 하. 룬트벡 아크티에 셀스카브 인돌 및 2,3-디히드로인돌 유도체, 그들의 제조방법 및 사용
FR2769312B1 (fr) * 1997-10-03 1999-12-03 Adir Nouveaux composes de l'indanol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
JP2002519323A (ja) 2002-07-02
DE69903239T2 (de) 2003-09-11
WO2000000198A1 (en) 2000-01-06
CA2336117A1 (en) 2000-01-06
PE20000763A1 (es) 2000-08-30
WO2000000198A8 (en) 2000-03-23
AU4726699A (en) 2000-01-17
AR019178A1 (es) 2001-12-26
US6436964B1 (en) 2002-08-20
ES2181366T3 (es) 2003-02-16
CO5080791A1 (es) 2001-09-25
DE69903239D1 (de) 2002-11-07
EP0982304B1 (de) 2002-10-02
EP0982304A1 (de) 2000-03-01

Similar Documents

Publication Publication Date Title
DE69903239D1 (de) Auf serotonin-verwandte Systeme wirkende Piperidin-Derivate
IS5807A (is) Þíóbensimídasólafleiður
NO20000160L (no) Borekaksinjeksjonsystem
DE69934788D1 (de) Biozide benzylbiphenylderivative
NO20016334D0 (no) Boresystem
DE59912742D1 (de) Substituierte pyrazolderivate
ATE310742T1 (de) C-4ß-SUBSTITUTIERTE MACROLID-DERIVATE
DE59903417D1 (de) Leitungsführungsanordnung
ATE278695T1 (de) Piperidinderivate
DK0921171T3 (da) Glycoloplösningsboresystem
NO20015172D0 (no) 1-Metyl-erytromycin-derivater
DE69707782D1 (de) 4-Hydroxypiperidinderivate
ATE255098T1 (de) Substituierte chromanderivate
NO20002190L (no) 2-halo-6-O-substituerte ketolidderivater
ATE255099T1 (de) Substituierte chromanderivate
NO20000063D0 (no) Nye IL-5 inhiberende 6-azauracilderivater
NO20014362D0 (no) Erytromycinderivater
PT1140890E (pt) Derivados de cromano
NO992302L (no) Piperidin-derivater
ATE205830T1 (de) 4-hydroxypiperidinderivate
DK0990654T3 (da) Substituerede cyclobutylaminderivater
ATE215947T1 (de) Piperidinylmethyloxazolidinon-derivat
DK1140873T3 (da) IL-5-inhiberende 6-azauracilderivater
NO20001778D0 (no) Substituerte piperidinderivater
DE69919026D1 (de) Quervernetzer basierend auf dibenzalaceton-derivaten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties