ATE226200T1 - Asymmetrische synthese von chiralen sekondären alkoholen - Google Patents

Asymmetrische synthese von chiralen sekondären alkoholen

Info

Publication number
ATE226200T1
ATE226200T1 AT95920478T AT95920478T ATE226200T1 AT E226200 T1 ATE226200 T1 AT E226200T1 AT 95920478 T AT95920478 T AT 95920478T AT 95920478 T AT95920478 T AT 95920478T AT E226200 T1 ATE226200 T1 AT E226200T1
Authority
AT
Austria
Prior art keywords
chiral secondary
asymmetric synthesis
secondary alcohols
chiral
secondary alcohol
Prior art date
Application number
AT95920478T
Other languages
English (en)
Inventor
J Peter Klein
Alistair J Leigh
John Michnick
Anil M Kumar
Gail E Underiner
Original Assignee
Cell Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapeutics Inc filed Critical Cell Therapeutics Inc
Application granted granted Critical
Publication of ATE226200T1 publication Critical patent/ATE226200T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
AT95920478T 1994-05-16 1995-05-16 Asymmetrische synthese von chiralen sekondären alkoholen ATE226200T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24294494A 1994-05-16 1994-05-16
PCT/US1995/006178 WO1995031450A1 (en) 1994-05-16 1995-05-16 Asymmetric synthesis of chiral secondary alcohols

Publications (1)

Publication Number Publication Date
ATE226200T1 true ATE226200T1 (de) 2002-11-15

Family

ID=22916737

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95920478T ATE226200T1 (de) 1994-05-16 1995-05-16 Asymmetrische synthese von chiralen sekondären alkoholen

Country Status (7)

Country Link
US (1) US5629423A (de)
EP (1) EP0759915B1 (de)
JP (1) JPH10507156A (de)
AT (1) ATE226200T1 (de)
CA (1) CA2190511A1 (de)
DE (1) DE69528585D1 (de)
WO (1) WO1995031450A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6693105B1 (en) 1992-11-16 2004-02-17 Cell Therapeutics, Inc. Hydroxyl-containing compounds
US6469017B1 (en) 1998-01-16 2002-10-22 Cell Therapeutics, Inc. Method of inhibiting interleukin-12 signaling
US6878715B1 (en) * 1994-02-18 2005-04-12 Cell Therapeutics, Inc. Therapeutic compounds for inhibiting interleukin-12 signals and method for using same
US6057328A (en) * 1997-12-31 2000-05-02 Cell Therapeutics, Inc. Method for treating hyperoxia
US6075029A (en) * 1998-01-02 2000-06-13 Cell Therapeutics, Inc. Xanthine modulators of metabolism of cellular P-450
JP2000063312A (ja) * 1998-08-17 2000-02-29 Mitsubishi Gas Chem Co Inc 光学活性２級アルコール及びその製造法
US6586429B2 (en) * 2000-11-29 2003-07-01 Cell Therapeutics, Inc. Tricyclic fused xanthine compounds and their uses
US6825180B2 (en) * 2001-05-18 2004-11-30 Cell Therapeutics, Inc. Pyridopyrimidine compounds and their uses
HRP20080297T3 (en) 2004-07-30 2008-07-31 Torrent Pharmaceuticals Ltd Nebivolol and its pharmaceutically acceptable salts, process for preparation and pharmaceutical compositions of nebivolol
EP1841448A2 (de) * 2004-12-30 2007-10-10 Diakine Therapeutics, Inc. Pharmazeutische zusammensetzungen und vefahren zur wiederherstellung der betazellmasse und funktion
KR20100121527A (ko) 2008-02-29 2010-11-17 콘서트 파마슈티컬즈, 인크. 치환된 잔틴 유도체
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US8952016B2 (en) 2009-02-27 2015-02-10 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
KR20150002779A (ko) 2012-04-13 2015-01-07 콘서트 파마슈티컬즈, 인크. 치환된 크산틴 유도체
CN106432109A (zh) * 2016-09-20 2017-02-22 江苏丰山集团股份有限公司 一种精喹禾灵的制备方法
CN113791144A (zh) * 2021-08-13 2021-12-14 四川绵竹剑南春酒厂有限公司 利用高效气相色谱检测白酒中手性乳酸乙酯的方法
CN114276521A (zh) * 2022-03-04 2022-04-05 西陇科学股份有限公司 一种应用于倒装芯片封装的高纯环氧树脂制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4408063A (en) * 1978-06-27 1983-10-04 Merck & Co., Inc. Preparation of epihalohydrin enantiomers
JPS62108854A (ja) * 1985-11-07 1987-05-20 Daicel Chem Ind Ltd ２−スルホニルオキシアルコ−ル類の製法
JP2585631B2 (ja) * 1987-10-06 1997-02-26 ライオン株式会社 光学活性エピハロヒドリンの製造方法
JPH0615534B2 (ja) * 1987-11-10 1994-03-02 ダイソー株式会社 光学活性エピクロルヒドリンの立体化学反転法
WO1989010350A1 (en) * 1988-04-21 1989-11-02 Ici Australia Operations Proprietary Limited Preparation of an epoxide
DE3942872A1 (de) * 1989-12-23 1991-06-27 Hoechst Ag Verfahren zur enantioselektiven darstellung von ((omega)-1)-hydroxyalkylxanthinen
US5097049A (en) * 1990-05-03 1992-03-17 Eli Lilly And Company Process and intermediates for chiral epoxides
US5243096A (en) * 1990-06-14 1993-09-07 Asahi Denka Kogyo K.K. Optically active pentane derivatives and intermediates thereof, and process for manufacturing same
ATE230990T1 (de) * 1992-03-04 2003-02-15 Cell Therapeutics Inc Enantiomere hydroxylierte xanthinverbindungen

Also Published As

Publication number Publication date
DE69528585D1 (de) 2002-11-21
JPH10507156A (ja) 1998-07-14
CA2190511A1 (en) 1995-11-23
US5629423A (en) 1997-05-13
EP0759915B1 (de) 2002-10-16
WO1995031450A1 (en) 1995-11-23
EP0759915A1 (de) 1997-03-05

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Legal Events

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REZ Deleted due to withdrawal
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties