ATE228826T1 - Methode zur herstellung von partikeln mit verzoegerter freisetzung - Google Patents

Methode zur herstellung von partikeln mit verzoegerter freisetzung

Info

Publication number
ATE228826T1
ATE228826T1 AT96935641T AT96935641T ATE228826T1 AT E228826 T1 ATE228826 T1 AT E228826T1 AT 96935641 T AT96935641 T AT 96935641T AT 96935641 T AT96935641 T AT 96935641T AT E228826 T1 ATE228826 T1 AT E228826T1
Authority
AT
Austria
Prior art keywords
core particles
delayed release
release particles
organic solvent
active substance
Prior art date
Application number
AT96935641T
Other languages
English (en)
Inventor
Nils-Ove Gustafsson
Timo Laakso
Peter Fyhr
Monica Joensson
Original Assignee
Bioglan Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioglan Ab filed Critical Bioglan Ab
Application granted granted Critical
Publication of ATE228826T1 publication Critical patent/ATE228826T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96935641T 1995-10-19 1996-09-03 Methode zur herstellung von partikeln mit verzoegerter freisetzung ATE228826T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9503672A SE505146C2 (sv) 1995-10-19 1995-10-19 Partiklar för fördröjd frisättning
PCT/SE1996/001091 WO1997014408A1 (en) 1995-10-19 1996-09-03 Sustained release particles

Publications (1)

Publication Number Publication Date
ATE228826T1 true ATE228826T1 (de) 2002-12-15

Family

ID=20399887

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01117830T ATE326953T1 (de) 1995-10-19 1996-09-03 Umhüllung kleiner partikel
AT96935641T ATE228826T1 (de) 1995-10-19 1996-09-03 Methode zur herstellung von partikeln mit verzoegerter freisetzung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01117830T ATE326953T1 (de) 1995-10-19 1996-09-03 Umhüllung kleiner partikel

Country Status (16)

Country Link
US (1) US6120787A (de)
EP (3) EP1142569B1 (de)
JP (1) JP2000501380A (de)
KR (1) KR100482262B1 (de)
AT (2) ATE326953T1 (de)
AU (1) AU699080B2 (de)
CZ (1) CZ293059B6 (de)
DE (3) DE869774T1 (de)
DK (1) DK0869774T3 (de)
ES (2) ES2125209T3 (de)
HU (1) HUP9901205A3 (de)
IL (1) IL124052A (de)
NO (1) NO320392B1 (de)
PT (1) PT869774E (de)
SE (1) SE505146C2 (de)
WO (1) WO1997014408A1 (de)

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Also Published As

Publication number Publication date
HUP9901205A3 (en) 2001-04-28
ATE326953T1 (de) 2006-06-15
NO981558D0 (no) 1998-04-06
EP1142569B1 (de) 2006-05-24
ES2125209T1 (es) 1999-03-01
DE69636177T2 (de) 2007-03-29
DE69625240D1 (de) 2003-01-16
AU7347896A (en) 1997-05-07
JP2000501380A (ja) 2000-02-08
DE69625240T2 (de) 2003-09-11
AU699080B2 (en) 1998-11-19
DE869774T1 (de) 1999-06-02
SE9503672D0 (sv) 1995-10-19
HUP9901205A2 (hu) 1999-08-30
US6120787A (en) 2000-09-19
HK1011182A1 (en) 1999-07-09
DK0869774T3 (da) 2003-03-24
EP0869774A1 (de) 1998-10-14
SE505146C2 (sv) 1997-06-30
CZ293059B6 (cs) 2004-01-14
WO1997014408A1 (en) 1997-04-24
EP1142569A3 (de) 2003-05-21
KR19990064267A (ko) 1999-07-26
DE69636177D1 (de) 2006-06-29
ES2267637T3 (es) 2007-03-16
PT869774E (pt) 2003-04-30
ES2125209T3 (es) 2003-07-01
KR100482262B1 (ko) 2006-04-14
SE9503672L (sv) 1997-04-20
CZ117398A3 (cs) 1998-09-16
EP1716849A1 (de) 2006-11-02
EP0869774B1 (de) 2002-12-04
NO981558L (no) 1998-04-06
NO320392B1 (no) 2005-11-28
IL124052A (en) 2000-11-21
EP1142569A2 (de) 2001-10-10

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