ATE231485T1 - Verfahren zur herstellung von arylmalonaten - Google Patents
Verfahren zur herstellung von arylmalonatenInfo
- Publication number
- ATE231485T1 ATE231485T1 AT98911685T AT98911685T ATE231485T1 AT E231485 T1 ATE231485 T1 AT E231485T1 AT 98911685 T AT98911685 T AT 98911685T AT 98911685 T AT98911685 T AT 98911685T AT E231485 T1 ATE231485 T1 AT E231485T1
- Authority
- AT
- Austria
- Prior art keywords
- arylmalonates
- producing
- formula
- preparation
- dialkyl
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- -1 alkyl chloroformate Chemical compound 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000004973 liquid crystal related substance Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/820,277 US5750766A (en) | 1997-03-18 | 1997-03-18 | Process for the preparation of arylmalonates |
| US08/820,268 US5756815A (en) | 1997-03-18 | 1997-03-18 | Process for the preparation arylamalonates |
| PCT/US1998/005125 WO1998041496A1 (en) | 1997-03-18 | 1998-03-16 | Process for the preparation of arylmalonates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE231485T1 true ATE231485T1 (de) | 2003-02-15 |
Family
ID=27124436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98911685T ATE231485T1 (de) | 1997-03-18 | 1998-03-16 | Verfahren zur herstellung von arylmalonaten |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0984919B1 (de) |
| AT (1) | ATE231485T1 (de) |
| AU (1) | AU6558498A (de) |
| DE (1) | DE69810924T2 (de) |
| DK (1) | DK0984919T3 (de) |
| ES (1) | ES2191288T3 (de) |
| WO (1) | WO1998041496A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7419982B2 (en) | 2003-09-24 | 2008-09-02 | Wyeth Holdings Corporation | Crystalline forms of 5-chloro-6-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-N-[(1S)-2,2,2-trifluoro-1-methylethyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine salts |
| KR20060098368A (ko) | 2003-09-24 | 2006-09-18 | 와이어쓰 홀딩스 코포레이션 | 항암제로서의 6-[(치환된)페닐]트리아졸로피리미딘 |
| CN100486580C (zh) | 2003-09-24 | 2009-05-13 | 惠氏控股公司 | 作为抗癌剂的6-芳基-7-卤基-咪唑并[1,2-a]嘧啶 |
| MY179926A (en) | 2003-12-08 | 2020-11-19 | Wyeth Corp | Process for the preparation of tubulin inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2367632A (en) * | 1942-07-30 | 1945-01-16 | Mallinckrodt Chemical Works | Carbalkoxylation of organic compounds |
| DE2509017C2 (de) * | 1975-03-01 | 1983-03-03 | Dynamit Nobel Ag, 5210 Troisdorf | Verfahren zur Herstellung von Phenylmalonsäuredialkylestern |
| JPS5337637A (en) * | 1976-09-14 | 1978-04-06 | Nippon Soda Co Ltd | Preparation of phenylmalonic acid diester derivatives |
-
1998
- 1998-03-16 WO PCT/US1998/005125 patent/WO1998041496A1/en not_active Ceased
- 1998-03-16 DK DK98911685T patent/DK0984919T3/da active
- 1998-03-16 DE DE69810924T patent/DE69810924T2/de not_active Expired - Fee Related
- 1998-03-16 AT AT98911685T patent/ATE231485T1/de not_active IP Right Cessation
- 1998-03-16 EP EP98911685A patent/EP0984919B1/de not_active Expired - Lifetime
- 1998-03-16 AU AU65584/98A patent/AU6558498A/en not_active Abandoned
- 1998-03-16 ES ES98911685T patent/ES2191288T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69810924T2 (de) | 2003-09-04 |
| ES2191288T3 (es) | 2003-09-01 |
| EP0984919B1 (de) | 2003-01-22 |
| EP0984919A4 (de) | 2000-07-12 |
| DK0984919T3 (da) | 2003-05-12 |
| DE69810924D1 (de) | 2003-02-27 |
| AU6558498A (en) | 1998-10-12 |
| EP0984919A1 (de) | 2000-03-15 |
| WO1998041496A1 (en) | 1998-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0984919 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |