ATE231733T1 - Gasbetätigtes element zum austragen von genmaterial - Google Patents

Gasbetätigtes element zum austragen von genmaterial

Info

Publication number
ATE231733T1
ATE231733T1 AT95909280T AT95909280T ATE231733T1 AT E231733 T1 ATE231733 T1 AT E231733T1 AT 95909280 T AT95909280 T AT 95909280T AT 95909280 T AT95909280 T AT 95909280T AT E231733 T1 ATE231733 T1 AT E231733T1
Authority
AT
Austria
Prior art keywords
particles
genetic material
discharging
gas
actuated element
Prior art date
Application number
AT95909280T
Other languages
English (en)
Inventor
Dennis E Mccabe
Original Assignee
Powderject Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Powderject Vaccines Inc filed Critical Powderject Vaccines Inc
Application granted granted Critical
Publication of ATE231733T1 publication Critical patent/ATE231733T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A61M2005/005—Magazines with multiple ampoules directly inserted into an injection or infusion device, e.g. revolver-like magazines containing ampoules with or without needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Other Surface Treatments For Metallic Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Air Bags (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
AT95909280T 1994-01-21 1995-01-20 Gasbetätigtes element zum austragen von genmaterial ATE231733T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18481294A 1994-01-21 1994-01-21
PCT/US1995/000780 WO1995019799A1 (en) 1994-01-21 1995-01-20 Gas driven gene delivery instrument

Publications (1)

Publication Number Publication Date
ATE231733T1 true ATE231733T1 (de) 2003-02-15

Family

ID=22678443

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02023522T ATE300609T1 (de) 1994-01-21 1995-01-20 Gasbetätigtes element zum austragen von genmaterial
AT95909280T ATE231733T1 (de) 1994-01-21 1995-01-20 Gasbetätigtes element zum austragen von genmaterial

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT02023522T ATE300609T1 (de) 1994-01-21 1995-01-20 Gasbetätigtes element zum austragen von genmaterial

Country Status (15)

Country Link
US (2) US5584807A (de)
EP (3) EP1550713A3 (de)
JP (1) JP3221683B2 (de)
CN (1) CN1112943C (de)
AT (2) ATE300609T1 (de)
AU (1) AU674815B2 (de)
BR (1) BR9505691A (de)
CA (2) CA2158733C (de)
DE (2) DE69529495T2 (de)
DK (2) DK0690732T3 (de)
ES (2) ES2192573T3 (de)
NZ (1) NZ279995A (de)
PT (1) PT690732E (de)
RU (1) RU2134295C1 (de)
WO (1) WO1995019799A1 (de)

Families Citing this family (203)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW360548B (en) * 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
DK0690732T3 (da) * 1994-01-21 2003-05-19 Powderject Vaccines Inc Gasdrevet genindførselsinstrument
US5899880A (en) * 1994-04-08 1999-05-04 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
GB9416663D0 (en) 1994-08-17 1994-10-12 Oxford Bioscience Limited Particle delivery
EP0788386B1 (de) * 1994-10-24 1999-01-13 PowderJect Research Limited Nadellose spritze
GB9426379D0 (en) 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
GB9502879D0 (en) * 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
US7223739B1 (en) * 1995-06-07 2007-05-29 Powderject Vaccines, Inc. Adjuvanted genetic vaccines
US6013050A (en) * 1995-10-20 2000-01-11 Powderject Research Limited Particle delivery
US5922685A (en) * 1996-06-05 1999-07-13 Powderject Vaccines, Inc. IL-12 gene therapy of tumors
CA2257357C (en) 1996-06-07 2010-04-13 Neorx Corporation Humanized antibodies with modified glycosylation
CA2257141C (en) * 1996-06-14 2006-11-28 Powderject Vaccines, Inc. Sample delivery module for particle acceleration apparatus
US6893664B1 (en) 1996-06-17 2005-05-17 Powderject Research Limited Particle delivery techniques
DE69738399T2 (de) * 1996-09-25 2008-12-04 Powderject Vaccines, Inc., Madison Gasbetriebenes gerät für teilchenabgabe
US5733600A (en) * 1996-11-13 1998-03-31 Powderject Vaccines, Inc. Method and apparatus for preparing sample cartridges for a particle acceleration device
DE19648625A1 (de) * 1996-11-13 1998-05-14 Soft Gene Gmbh Mikroprojektil für das Einbringen von Substanzen in Zellen durch ballistischen Transfer
DE19648656B4 (de) * 1996-11-14 2005-08-11 Hiper Ceramics Gmbh Vorrichtung zum Beschleunigen von Partikeln auf Zellen zum ballistischen Transfer
US6200959B1 (en) * 1996-12-04 2001-03-13 Powerject Vaccines Inc. Genetic induction of anti-viral immune response and genetic vaccine for filovirus
US6433154B1 (en) 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
US5947928A (en) * 1997-06-19 1999-09-07 Mile Creek Capital, Llc Drug delivery system
US7378506B2 (en) * 1997-07-21 2008-05-27 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US6639050B1 (en) 1997-07-21 2003-10-28 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US6548642B1 (en) * 1997-07-21 2003-04-15 Ohio University Synthetic genes for plant gums
US6570062B1 (en) 1997-07-21 2003-05-27 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US6355415B1 (en) 1997-09-29 2002-03-12 Ohio University Compositions and methods for the use of ribozymes to determine gene function
US5994624A (en) * 1997-10-20 1999-11-30 Cotton Incorporated In planta method for the production of transgenic plants
ATE316796T1 (de) * 1997-11-20 2006-02-15 Us Army Medical Res And Materi Dna impfstoffe gegen zecken-flavivieren
US6475994B2 (en) * 1998-01-07 2002-11-05 Donald A. Tomalia Method and articles for transfection of genetic material
US20020147143A1 (en) 1998-03-18 2002-10-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6706948B1 (en) 1998-03-19 2004-03-16 The United States Of America As Represented By The Secretary Of Agriculture Sugarcane UBI9 gene promoter and methods of use thereof
US6686513B1 (en) 1998-03-19 2004-02-03 The United States Of America As Represented By The Secretary Of Agriculture Sugarcane ubi9 gene promoter sequence and methods of use thereof
EP1079791A4 (de) 1998-05-12 2003-09-03 Susan C Bock Menschliches antithrombin iii und damit verbundene methoden
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
EP1086214B1 (de) * 1998-06-10 2009-11-25 Georgia Tech Research Corporation Mikronadel-einrichtungen und verfahren zur deren herstellung
US20030235557A1 (en) 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
NZ511798A (en) * 1998-10-19 2004-01-30 Powderject Vaccines Inc Minimal promoters comprising a promoter not linked to its native enhancer and such minimal promoters linked to an antigen
US6881723B1 (en) 1998-11-05 2005-04-19 Powderject Vaccines, Inc. Nucleic acid constructs
US6232113B1 (en) 1998-12-08 2001-05-15 Tien-Li Lee Particle bombardment device
AU3593200A (en) 1999-02-09 2000-08-29 Powderject Vaccines, Inc. (mycobacterium tuberculosis), immunization
JP2002542264A (ja) * 1999-04-21 2002-12-10 パウダージェクト ヴァクシンズ，インコーポレイテッド 核酸による免疫化
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6398808B1 (en) * 1999-06-15 2002-06-04 Scimed Life Systems, Inc. Localized delivery of genetic information from biostable materials
ATE285806T1 (de) 1999-10-11 2005-01-15 Felton International Inc Universelle antiinfektionsschutzvorrichtung für nadellose injektoren
US7074210B2 (en) * 1999-10-11 2006-07-11 Felton International, Inc. Universal protector cap with auto-disable features for needle-free injectors
US7135282B1 (en) 1999-10-14 2006-11-14 The Dow Chemical Company Viral particles with exogenous internal epitopes
JP2004522403A (ja) * 1999-11-03 2004-07-29 パウダージェクト ヴァクシンズ，インコーポレイテッド 抗原発現を駆動する哺乳動物ｃｄ８０／ｃｄ８６遺伝子プロモーターを有する核酸ワクチン組成物
SI1227840T1 (sl) * 1999-11-03 2008-02-29 Powderject Vaccines Inc Genetske vakcine z adjuvansom
US7196066B1 (en) 1999-11-03 2007-03-27 Powderject Vaccines, Inc. DNA-vaccines based on constructs derived from the genomes of human and animal pathogens
CN100333794C (zh) * 1999-11-03 2007-08-29 宝德杰克特疫苗有限公司 佐剂化的基因疫苗
US20040234539A1 (en) * 1999-11-03 2004-11-25 Powderject Research Limited Nucleic acid vaccine compositions having a mammalian cd80/cd86 gene promoter driving antigen expression
US20040109874A1 (en) * 1999-11-10 2004-06-10 Powderject Vaccines, Inc. Induction of mucosal immunity by vaccination via the skin route
US6770054B1 (en) 1999-11-23 2004-08-03 Felton International, Inc. Injector assembly with driving means and locking means
US7887506B1 (en) 1999-11-23 2011-02-15 Pulse Needlefree Systems, Inc. Safety mechanism to prevent accidental patient injection and methods of same
US7029457B2 (en) * 1999-11-23 2006-04-18 Felton International, Inc. Jet injector with hand piece
CN1079430C (zh) * 1999-12-11 2002-02-20 周芳 一种高压气体基因枪
FR2802820B1 (fr) 1999-12-27 2002-10-18 Poudres & Explosifs Ste Nale Seringue sans aiguille fonctionnant par effet tube a choc, avec maintien prealable du principe actif sur le cote
IL151097A0 (en) 2000-02-23 2003-04-10 Smithkline Beecham Biolog Tumour-specific animal proteins
GB0006263D0 (en) * 2000-03-15 2000-05-03 Powderject Res Ltd Apparatus and method for adjusting the characteristics of a needleless syringe
GB0008494D0 (en) 2000-04-07 2000-05-24 Secr Defence Microprojectile delivery system
US6716190B1 (en) * 2000-04-19 2004-04-06 Scimed Life Systems, Inc. Device and methods for the delivery and injection of therapeutic and diagnostic agents to a target site within a body
AU2001261625B2 (en) 2000-05-16 2006-04-06 Regents Of The University Of Minnesota High mass throughput particle generation using multiple nozzle spraying
AR029540A1 (es) 2000-06-28 2003-07-02 Corixa Corp COMPOSICIONES Y METODOS PARA EL DIAGNoSTICO Y LA TERAPIA DE CA NCER DE PULMoN
US6878861B2 (en) * 2000-07-21 2005-04-12 Washington State University Research Foundation Acyl coenzyme A thioesterases
GB0025710D0 (en) * 2000-10-20 2000-12-06 Medical Res Council Biolistic device
CA2324045A1 (fr) 2000-10-20 2002-04-20 Universite De Sherbrooke Seringue sans aiguille pour l'injection sous-cutanee de poudres medicamenteuses
US7060442B2 (en) * 2000-10-30 2006-06-13 Regents Of The University Of Michigan Modulators on Nod2 signaling
JP2004535358A (ja) * 2000-11-02 2004-11-25 パウダージェクト ワクチンズ，インコーポレーテッド 核酸免疫
EP1330516B1 (de) * 2000-11-03 2007-01-17 The Regents Of The University Of Michigan Oberflächentransfektion und expressionsverfahren
US6897067B2 (en) * 2000-11-03 2005-05-24 Regents Of The University Of Michigan Surface transfection and expression procedure
US6902933B2 (en) * 2000-11-03 2005-06-07 Regents Of The University Of Michigan Surface transfection and expression procedure
US7226764B1 (en) 2000-11-08 2007-06-05 The Board Of Trustees Operating Michigan State University Compositions and methods for the synthesis and subsequent modification of uridine-5′-diphosphosulfoquinovose (UDP-SQ)
US6638246B1 (en) * 2000-11-28 2003-10-28 Scimed Life Systems, Inc. Medical device for delivery of a biologically active material to a lumen
US7255865B2 (en) * 2000-12-05 2007-08-14 Allergan, Inc. Methods of administering botulinum toxin
EP1345646A2 (de) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Mikronadel-vorrichtungen und deren herstellung
GB0100756D0 (en) 2001-01-11 2001-02-21 Powderject Res Ltd Needleless syringe
CA2340998C (en) 2001-03-21 2012-01-03 Saskatchewan Wheat Pool Selective modification of plant fatty acids
US7241935B2 (en) * 2001-04-13 2007-07-10 The Board Of Trustees Operating Michigan State University Compositions and methods for the production of betaine lipids
US7169597B2 (en) * 2001-04-13 2007-01-30 Michigan State University Compositions and methods for the production of betaine lipids
JP2005504513A (ja) 2001-05-09 2005-02-17 コリクサ コーポレイション 前立腺癌の治療及び診断のための組成物及び方法
US7247338B2 (en) 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
US20030033637A1 (en) * 2001-06-05 2003-02-13 Croptech Corporation Gene expression and production of TGF-beta proteins including bioactive mullerian inhibiting substance from plants
US8061006B2 (en) 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
WO2003020936A1 (en) * 2001-08-31 2003-03-13 The Dow Chemical Company Nucleic acid compositions conferring altered metabolic characteristics
US8361037B2 (en) * 2001-09-19 2013-01-29 Valeritas, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
MXPA04002631A (es) * 2001-09-20 2004-07-08 Glaxo Group Ltd Vacunas de adn optimizadas por codon gag-vih.
US8920375B2 (en) * 2001-09-21 2014-12-30 Valeritas, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
AU2002343457A1 (en) * 2001-09-28 2003-04-07 Biovalve Technologies, Inc. Switchable microneedle arrays and systems and methods relating to same
EP1469903A2 (de) * 2001-09-28 2004-10-27 BioValve Technologies, Inc. Mikronadel mit membran
US20040048822A1 (en) * 2001-11-01 2004-03-11 Juan Harrison Nucleic acid immunization
JP2003164289A (ja) * 2001-11-30 2003-06-10 Seikagaku Kogyo Co Ltd 骨組織導入用遺伝子
DK2224012T3 (da) 2001-12-17 2013-05-13 Corixa Corp Sammensætninger og fremgangsmåder til terapi og diagnose af inflammatoriske tarmsygdomme
ATE357219T1 (de) * 2002-01-25 2007-04-15 Glaxo Group Ltd Darreichungsformen für dns
US7255986B2 (en) * 2002-01-31 2007-08-14 The Board Of Trustees Operating Michigan State University Compositions for the diagnosis and treatment of epizootic catarrhal enteritis in ferrets
US20030163111A1 (en) * 2002-02-26 2003-08-28 Daellenbach Keith K. End effector for needle-free injection system
CN1665934B (zh) 2002-03-19 2010-05-26 国际植物研究所 GNTIII(UDP-N乙酰葡萄糖胺:β-D-甘露糖苷β(1,4)-N-乙酰葡萄糖胺基-转移酶III)在植物中的表达
CN101613705A (zh) 2002-03-19 2009-12-30 国际植物研究所 在植物中优化聚糖生成
CA2380671A1 (fr) * 2002-04-05 2003-10-05 Stephane Dufresne Seringue sans aiguille pour l'injection sous-cutanee de gouttelettes medicamenteuses
US7078037B2 (en) * 2002-04-19 2006-07-18 The Arizona Board Of Regents On Behalf Of The University Of Arizona Peptides and DNA encoding the peptides useful for immunizations against Coccidioides spp. infections
USD488862S1 (en) 2002-06-04 2004-04-20 Felton International, Inc. Handpiece for jet injector
WO2004001003A2 (en) * 2002-06-20 2003-12-31 Board Of Trustees Operating Michigan State University Plastid division and related genes and proteins, and methods of use
US7329798B2 (en) * 2002-06-28 2008-02-12 University Of Guelph Harvest-inducible regulatory elements and methods of using same
CA2490781A1 (en) 2002-06-28 2004-01-08 University Of Guelph Harvest-inducible genes from alfalfa (medicago sativa) and methods of use thereof
JP2006500062A (ja) * 2002-09-27 2006-01-05 パウダージェクト リサーチ リミテッド 遺伝子発現のための核酸構築物
JP4791730B2 (ja) * 2002-09-27 2011-10-12 パウダージェクト リサーチ リミテッド 核酸コーティング粒子
US6920521B2 (en) * 2002-10-10 2005-07-19 International Business Machines Corporation Method and system of managing virtualized physical memory in a data processing system
US6863731B2 (en) * 2002-10-18 2005-03-08 Controls Corporation Of America System for deposition of inert barrier coating to increase corrosion resistance
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
CN101863930A (zh) 2003-01-06 2010-10-20 科里克萨有限公司 一些氨烷基氨基葡糖苷磷酸酯化合物和它们的用途
FR2850564B1 (fr) * 2003-02-05 2006-06-02 Arcadophta Dispositif et procede de preparation extemporanee d'une quantite individuelle de fluide sterile
US7262027B2 (en) * 2003-03-14 2007-08-28 Medical College Of Ohio Polypeptide and DNA immunization against Coccidioides spp. infections
EP2207036B1 (de) * 2003-03-24 2012-12-12 Gen-Probe Transplant Diagnostics, Inc. Methoden zur Messung der Negativkontrolle in Mehrfachanalyt-Assays
US20060252120A1 (en) * 2003-05-09 2006-11-09 Kieliszewski Marcia J Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US7655833B2 (en) * 2003-05-29 2010-02-02 Brookhaven Science Associates, Llc ADS genes for reducing saturated fatty acid levels in seed oils
GB0321615D0 (en) 2003-09-15 2003-10-15 Glaxo Group Ltd Improvements in vaccination
PT1685251E (pt) * 2003-10-10 2014-04-15 Powderject Vaccines Inc Construções de ácido nucleico
USD519633S1 (en) 2003-11-12 2006-04-25 Powderject Research Limited Syringe
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
MXPA06008126A (es) * 2004-01-14 2008-02-14 Univ Ohio Metodos para la produccion de peptidos/proteinas en plantas y peptidos/proteinas producidos de este modo.
US7432057B2 (en) * 2004-01-30 2008-10-07 Michigan State University Genetic test for PSE-susceptible turkeys
AU2004201456B2 (en) * 2004-04-08 2005-11-17 Ronald Allan Greenberg Apparatus and method for transdermal delivery of fluids including oxygen
US8623812B2 (en) * 2004-04-19 2014-01-07 Ohio University Cross-linkable glycoproteins and methods of making the same
US7217428B2 (en) * 2004-05-28 2007-05-15 Technology Innovations Llc Drug delivery apparatus utilizing cantilever
WO2006013072A2 (en) 2004-08-02 2006-02-09 Basf Plant Science Gmbh Method for isolation of transcription termination sequences
NZ553776A (en) 2004-09-22 2010-05-28 Glaxosmithkline Biolog Sa Immunogenic composition comprising staphylococcal PNAG and Type 5 and/or 8 Capsular polysaccharide or oligosaccharide.
GB0507997D0 (en) * 2005-02-01 2005-05-25 Powderject Vaccines Inc Nucleic acid constructs
WO2006086782A2 (en) * 2005-02-11 2006-08-17 The Regents Of The University Of California Pneumatic capillary gun for ballistic delivery of microscopic particles into tissue
EP2166100B1 (de) 2005-03-08 2012-07-18 BASF Plant Science GmbH Expressionsverstärkende Intronsequenzen
CA2608717A1 (en) * 2005-05-18 2006-11-23 The Board Of Trustees Operating Michigan State University Resistance to soybean aphid in early maturing soybean germplasm
US20080242834A1 (en) * 2005-07-08 2008-10-02 Ohio University Methods of Predicting Hyp-Glycosylation Sites For Proteins Expressed and Secreted in Plant Cells, and Related Methods and Products
US8591457B2 (en) * 2005-08-10 2013-11-26 Alza Corporation Method for making a needle-free jet injection drug delivery device
US8562620B2 (en) * 2008-04-21 2013-10-22 Dfine, Inc. Bone treatment systems
EP2441846A3 (de) 2006-01-09 2012-07-25 The Regents Of the University of California Immunstimulierende Kombinationen aus TNFRSF, TLR, NLR, RHR, purinergischem Rezeptor, und Zytokin-Rezeptor-Antagonisten für Impfstoffe und die Tumorimmuntherapie
US20080313769A9 (en) 2006-01-12 2008-12-18 Athenix Corporation EPSP synthase domains conferring glyphosate resistance
US20070164133A1 (en) * 2006-01-18 2007-07-19 Hao-Jan Lin Low pressure gas accelerated gene gun
WO2007089883A2 (en) 2006-01-31 2007-08-09 Nanocopoeia, Inc. Nanoparticle coating of surfaces
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
US7951428B2 (en) 2006-01-31 2011-05-31 Regents Of The University Of Minnesota Electrospray coating of objects
US20070190635A1 (en) * 2006-02-10 2007-08-16 Hai-Lung Huang Percussion mechanism for a gene gun
EP1996009A4 (de) 2006-03-02 2009-09-30 Athenix Corp Verfahren und zusammensetzungen für erhöhte enzymaktivität bei transgenen pflanzen
EP2101724B1 (de) 2006-05-11 2020-12-02 Regenics AS Verabreichung von zellextrakten zur verjüngung
US7977535B2 (en) 2006-07-12 2011-07-12 Board Of Trustees Of Michigan State University DNA encoding ring zinc-finger protein and the use of the DNA in vectors and bacteria and in plants
US8680235B2 (en) * 2006-09-22 2014-03-25 Stowers Institute For Medical Research Branchiostoma derived fluorescent proteins
US20090061492A1 (en) * 2006-11-15 2009-03-05 The Board Of Trustees For Michigan State University System Method for producing biodiesel
US9040816B2 (en) 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
EP2121720A4 (de) 2007-02-12 2010-05-12 Us Army Dna-impfstoffe auf basis von puumala-virus m-segmenten mit voller länge
GB0708758D0 (en) 2007-05-04 2007-06-13 Powderject Res Ltd Particle cassettes and process thereof
DE102007026752A1 (de) * 2007-06-09 2008-12-11 Ivonne Silvester Vorrichtung zur Aufbewahrung und Applikation von Wirkstoffen
JP2011500036A (ja) 2007-10-15 2011-01-06 ザ ユニバーシティー オブ クイーンズランド 構築物系およびその使用
EP2612867A1 (de) 2007-11-01 2013-07-10 Perseid Therapeutics LLC Immunsuppressive Polypeptide und Nucleinsäuren
WO2009137438A2 (en) 2008-05-06 2009-11-12 Wilson-Cook Medical Inc. Apparatus and methods for delivering therapeutic agents
US9133475B2 (en) 2008-11-26 2015-09-15 Board Of Trustees Of Michigan State University Aphid resistant soybean plants
US8362318B2 (en) 2008-12-18 2013-01-29 Board Of Trustees Of Michigan State University Enzyme directed oil biosynthesis in microalgae
AU2009330505A1 (en) 2008-12-23 2011-06-30 Cook Medical Technologies Llc Apparatus and methods for containing and delivering therapeutic agents
CN101768213B (zh) 2008-12-30 2012-05-30 中国科学院遗传与发育生物学研究所 一种与植物分蘖数目相关的蛋白及其编码基因与应用
CN101817879A (zh) 2009-02-26 2010-09-01 中国科学院遗传与发育生物学研究所 金属硫蛋白及其编码基因与应用
US8118777B2 (en) * 2009-05-29 2012-02-21 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
US9101744B2 (en) 2009-05-29 2015-08-11 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
TWI400103B (zh) * 2009-12-03 2013-07-01 Leader Machine Co Ltd Drug delivery device
US20110159577A1 (en) * 2009-12-30 2011-06-30 E. I. Du Pont De Nemours And Company Divider for use with biolistic bombardment device
WO2011082253A2 (en) 2009-12-30 2011-07-07 Board Of Trustees Of Michigan State University A method to produce acetyldiacylglycerols (ac-tags) by expression ofan acetyltransferase gene isolated from euonymus alatus (burning bush)
US9795658B2 (en) 2010-04-20 2017-10-24 Admedus Vaccines Pty Ltd Expression system for modulating an immune response
EP2566583B1 (de) 2010-05-06 2018-07-11 Regenics AS Verfahren zur Vorbereitung eines Fischeizellextrakts
US9227021B2 (en) * 2010-06-29 2016-01-05 Genesis Biosystems, Inc. Microneedle roller (MNR) infusion system
DK2621282T3 (da) 2010-09-28 2020-05-04 Univ California Gaba-agonister i behandlingen af forstyrrelser forbundet med metabolisk syndrom og gaba-kombinationer i behandling eller profylakse af type i diabetes
WO2012071281A2 (en) * 2010-11-23 2012-05-31 The Regents Of The University Of California Low-pressure biolistic barrels
GB201021881D0 (en) * 2010-12-23 2011-02-02 Profibrix Bv Powder delivery device
US9315826B2 (en) 2011-01-31 2016-04-19 The United States of America as rep. by the Sec'y of the Army, for U.S. Army Medical Research Institute of Infectious Diseases Nucleic acids containing a synthetic codon-optimized Sin Nombre virus full-length M gene
US10849975B2 (en) 2011-02-03 2020-12-01 Thomas Jefferson University Multivalent vaccines for rabies virus and filoviruses
US8486002B2 (en) * 2011-04-19 2013-07-16 Palo Alto Research Center Incorporated Drug delivery devices and methods with collimated gas stream and release-activatable tape
US8388569B2 (en) * 2011-04-19 2013-03-05 Xerox Corporation Delivery devices and methods with collimated gas stream and particle source
US8430839B2 (en) * 2011-04-19 2013-04-30 Palo Alto Research Center Incorporated Drug delivery devices and methods with collimated gas stream and drug reservoir
JP5851588B2 (ja) * 2011-04-27 2016-02-03 ビオムプＢｉｏｍ’Ｕｐ 生物医学止血用粉末ディスペンサ
DE102011100450B8 (de) * 2011-04-27 2013-10-17 Jörg Gerlach Apparat zum Sprühen von Zellen, Herstellung des Apparates, Methode zum Sprühen mit dem Apparat und eine Zellsuspension gesprüht mit dem Apparat
CA2837651A1 (en) 2011-06-21 2012-12-27 Oncofactor Corporation Compositions and methods for the therapy and diagnosis of cancer
CN102250757B (zh) * 2011-07-20 2013-01-09 宁波新芝生物科技股份有限公司 一种基因枪
EP3530283A1 (de) 2012-06-05 2019-08-28 The Australian National University Impfung mit interleukin-4-antagonisten
EP3459522B1 (de) 2012-12-10 2021-02-17 Regenics AS Verwendung von zellextrakten zur wundbehandlung
CA2836403A1 (en) 2013-01-04 2014-07-04 Board Of Trustees Of Michigan State University New sources of aphid resistance in soybean plants
US9783817B2 (en) 2013-03-04 2017-10-10 Arkansas State University Methods of expressing and detecting activity of expansin in plant cells
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
US9867931B2 (en) 2013-10-02 2018-01-16 Cook Medical Technologies Llc Therapeutic agents for delivery using a catheter and pressure source
US10392629B2 (en) 2014-01-17 2019-08-27 Board Of Trustees Of Michigan State University Increased caloric and nutritional content of plant biomass
US9714429B2 (en) 2014-01-28 2017-07-25 Arkansas State University Regulatory sequence of cupin family gene
AR100874A1 (es) 2014-06-16 2016-11-09 Consejo Nac De Investig Científicas Y Técnicas (Conicet) Genes quiméricos y proteínas de resistencia oxidativa, y plantas transgénicas que incluyen los mismos
US10449297B2 (en) * 2015-02-09 2019-10-22 Palo Alto Research Center Incorporated Alignment of elongated particles in a particle delivery device
US10039885B2 (en) 2015-02-09 2018-08-07 Palo Alto Research Center Incorporated System and method for enhancing particle delivery to biological tissue
WO2016154010A1 (en) 2015-03-20 2016-09-29 Makidon Paul Immunogenic compositions for use in vaccination against bordetella
JP2017000667A (ja) * 2015-06-16 2017-01-05 国立大学法人三重大学 無針注射器及びそれを用いた注射対象領域へのｄｎａ導入方法
WO2017096432A1 (en) 2015-12-09 2017-06-15 Admedus Vaccines Pty Ltd Immunomodulating composition for treatment
US11041170B2 (en) 2016-04-04 2021-06-22 Thomas Jefferson University Multivalent vaccines for rabies virus and coronaviruses
CN105820942B (zh) * 2016-05-24 2017-12-19 中国农业科学院棉花研究所 一种基因枪用活塞样品架
EP3468722B1 (de) 2016-06-14 2022-02-09 RenovaCare Sciences Corp. Modulare vorrichtung für zellsprühen
WO2018018082A1 (en) 2016-07-26 2018-02-01 The Australian National University Immunostimulatory compositions and uses therefor
FR3085959B1 (fr) * 2018-09-18 2020-11-20 Centre Nat Rech Scient Dispositif de distribution de microbulles pour une sonoporation cellulaire
US20210379118A1 (en) 2018-10-19 2021-12-09 Regenics As Use of egg cellular extract for wound healing
US20220396811A1 (en) * 2019-11-26 2022-12-15 Georgia Tech Research Corporation Systems and Devices for Delivering Cargo Material and Methods of Delivering Cargo Materials
WO2021195089A1 (en) 2020-03-23 2021-09-30 Sorrento Therapeutics, Inc. Fc-coronavirus antigen fusion proteins, and nucleic acids, vectors, compositions and methods of use thereof
CN115697176A (zh) 2020-06-05 2023-02-03 库克医学技术有限责任公司 用于递送治疗剂的医疗窥镜
EP4274648A4 (de) * 2021-01-10 2024-08-21 Orlance, Inc. Medizinische abgabevorrichtung
CN118139663A (zh) * 2021-06-24 2024-06-04 阿维塔斯有限公司 喷雾喷嘴
WO2023287654A1 (en) 2021-07-14 2023-01-19 Cook Medical Technologies, LLC Systems and methods for preventing clogging of a delivery system
US12496429B2 (en) 2022-10-18 2025-12-16 Cook Medical Technologies Llc Systems and methods for delivering pressurized fluid to a target site alone or in conjunction with therapeutic agents

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2632444A (en) * 1951-06-14 1953-03-24 Kas John Leo Pellet injector
US2850013A (en) * 1956-03-20 1958-09-02 Cordis Nat Animal pellet injector gun
US3518990A (en) * 1968-05-02 1970-07-07 Oscar H Banker Gun type inoculator
US3744493A (en) * 1972-01-10 1973-07-10 Syntex Corp Implanter having an improved cartridge ejector
GB8311345D0 (en) * 1983-04-26 1983-06-02 Dobson Park Ind Oral administration of capsules to animals
US4945050A (en) * 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
IL84459A (en) * 1986-12-05 1993-07-08 Agracetus Apparatus and method for the injection of carrier particles carrying genetic material into living cells
US5015580A (en) * 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
US5120657A (en) * 1986-12-05 1992-06-09 Agracetus, Inc. Apparatus for genetic transformation
US4941880A (en) * 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
CA1310870C (en) * 1987-11-16 1992-12-01 Medhi-Tek International Limited Apparatus for hypodermic injection of liquids
US5179022A (en) * 1988-02-29 1993-01-12 E. I. Du Pont De Nemours & Co. Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner
DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
CN1052695A (zh) * 1989-12-22 1991-07-03 中国科学院生物物理研究所 一种转移基因的方法及其转移基因的粒子枪
US5066587A (en) * 1990-01-26 1991-11-19 The Upjohn Company Gas driven microprojectile accelerator and method of use
US5204253A (en) * 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5149655A (en) * 1990-06-21 1992-09-22 Agracetus, Inc. Apparatus for genetic transformation
WO1992004439A1 (en) * 1990-08-30 1992-03-19 Brian John Bellhouse Ballistic apparatus
US5147295A (en) * 1991-01-23 1992-09-15 Ideal Instruments, Inc. Retractable implanter
TW360548B (en) * 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
DK0690732T3 (da) * 1994-01-21 2003-05-19 Powderject Vaccines Inc Gasdrevet genindførselsinstrument

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EP1550713A2 (de) 2005-07-06
BR9505691A (pt) 1996-01-16
EP1550713A3 (de) 2007-09-12
DE69534348D1 (de) 2005-09-01
DE69529495T2 (de) 2003-06-12
US5865796A (en) 1999-02-02
AU1729595A (en) 1995-08-08
RU2134295C1 (ru) 1999-08-10
HK1013804A1 (en) 1999-09-10
EP0690732B1 (de) 2003-01-29
ES2192573T3 (es) 2003-10-16
EP1293559B1 (de) 2005-07-27
WO1995019799A1 (en) 1995-07-27
DK1293559T3 (da) 2005-11-28
US5584807A (en) 1996-12-17
JPH08509131A (ja) 1996-10-01
PT690732E (pt) 2003-06-30
CA2501743A1 (en) 1995-07-27
ES2247248T3 (es) 2006-03-01
EP0690732A1 (de) 1996-01-10
EP0690732A4 (de) 1996-06-12
CA2501743C (en) 2008-11-18
DE69534348T2 (de) 2006-05-24
ATE300609T1 (de) 2005-08-15
DK0690732T3 (da) 2003-05-19
DE69529495D1 (de) 2003-03-06
EP1293559A1 (de) 2003-03-19
JP3221683B2 (ja) 2001-10-22
CA2158733C (en) 2007-01-16
CN1124460A (zh) 1996-06-12
CA2158733A1 (en) 1995-07-27
AU674815B2 (en) 1997-01-09
CN1112943C (zh) 2003-07-02

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