ATE231870T1 - Verfahren zur herstellung von 3-alkenylcephem- derivaten - Google Patents

Verfahren zur herstellung von 3-alkenylcephem- derivaten

Info

Publication number
ATE231870T1
ATE231870T1 AT98923112T AT98923112T ATE231870T1 AT E231870 T1 ATE231870 T1 AT E231870T1 AT 98923112 T AT98923112 T AT 98923112T AT 98923112 T AT98923112 T AT 98923112T AT E231870 T1 ATE231870 T1 AT E231870T1
Authority
AT
Austria
Prior art keywords
alkenylcephem
formula
derivatives
producing
chem
Prior art date
Application number
AT98923112T
Other languages
English (en)
Inventor
Yutaka Kameyama
Original Assignee
Otsuka Kagaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Kagaku Kk filed Critical Otsuka Kagaku Kk
Application granted granted Critical
Publication of ATE231870T1 publication Critical patent/ATE231870T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98923112T 1997-06-04 1998-06-04 Verfahren zur herstellung von 3-alkenylcephem- derivaten ATE231870T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16340397A JP4157177B2 (ja) 1997-06-04 1997-06-04 ３−アルケニルセフェム化合物の製造法
PCT/JP1998/002463 WO1998055485A1 (en) 1997-06-04 1998-06-04 Process for producing 3-alkenylcephem compounds

Publications (1)

Publication Number Publication Date
ATE231870T1 true ATE231870T1 (de) 2003-02-15

Family

ID=15773240

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98923112T ATE231870T1 (de) 1997-06-04 1998-06-04 Verfahren zur herstellung von 3-alkenylcephem- derivaten

Country Status (9)

Country Link
US (1) US6417351B1 (de)
EP (1) EP0990656B1 (de)
JP (1) JP4157177B2 (de)
KR (1) KR100338787B1 (de)
CN (1) CN1098267C (de)
AT (1) ATE231870T1 (de)
AU (1) AU7549998A (de)
DE (1) DE69811074D1 (de)
WO (1) WO1998055485A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050087791A (ko) * 2002-11-01 2005-08-31 오키드 케미칼즈 앤드 파마수티컬즈 리미티드 클로로메틸 세펨 유도체 제조를 위한 개선된 제조방법
WO2007013043A2 (en) * 2005-07-29 2007-02-01 Ranbaxy Laboratories Limited Processes for the preparation of 7-amino-3-vinyl cephalosporanic acid
CA2702257C (en) 2007-10-09 2016-07-12 Sopharmia, Inc. Broad spectrum beta-lactamase inhibitors
WO2010082108A1 (en) * 2009-01-16 2010-07-22 Nectar Lifesciences Ltd. Improved process for preparation of key intermediate of cephalosporins
CN102898440A (zh) * 2012-10-11 2013-01-30 南通康鑫药业有限公司 一种7-苯乙酰氨基-3-乙烯基头孢烷酸对甲氧苄酯的制备工艺
US9975905B2 (en) 2013-03-12 2018-05-22 Gladius Pharmaceuticals Corporation Derivatized 3-styryl-cephalosporins
EP2873736A1 (de) 2013-11-18 2015-05-20 Sandoz AG Chemoenzymatische Synthese des Cephalosporinzwischenprodukts 7-amino-3-alkenylcephem-4-Carbonsäure
CN103923104B (zh) * 2014-04-25 2016-04-13 湖北凌晟药业有限公司 7-苯乙酰氨基-3-乙烯基-4-头孢烯酸对甲氧基苄酯的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110534A (en) * 1970-01-23 1978-08-29 Glaxo Laboratories Limited Process for the preparation of 3-vinyl and substituted vinyl cephalosporins
US3755341A (en) * 1971-07-08 1973-08-28 Smith Kline French Lab Process of preparing pyridyl carbinols and ketones
ZA806977B (en) * 1979-11-19 1981-10-28 Fujisawa Pharmaceutical Co 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4409214A (en) 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4705851A (en) 1984-09-28 1987-11-10 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of 3-phosphoniummethyl-3-cephem compounds
JPS61269330A (ja) 1985-05-23 1986-11-28 Matsushita Electronics Corp 半導体装置の製造方法
JPS6320435A (ja) 1986-07-15 1988-01-28 Toopura:Kk ねじ部品
DE3933934A1 (de) 1989-10-03 1991-04-11 Bayer Ag Verfahren zur herstellung von 7-amino-3-((z)-1-propen-1-yl)-3-cephem-4-carbonsaeure
US5087177A (en) 1989-10-31 1992-02-11 Borg-Warner Automotive, Inc. Dual capacity fluid pump
GB9203327D0 (en) 1992-02-17 1992-04-01 Erba Carlo Spa Process for the synthesis of exomethylenecephams
US5502214A (en) * 1993-07-19 1996-03-26 Dana Farber Cancer Institute 1,2-benzoquinones and methods for making and using same
KR100257130B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법
US5874616A (en) * 1995-03-06 1999-02-23 Minnesota Mining And Manufacturing Company Preparation of bis (fluoroalkylenesulfonyl) imides and (fluoroalkysulfony) (fluorosulfonyl) imides
ATE221890T1 (de) * 1997-06-24 2002-08-15 Meiji Seika Kaisha Verfahren zur selektiven herstellung von z- isomeren von 3-(2-substituiertes vinyl)cephalosporinen

Also Published As

Publication number Publication date
WO1998055485A1 (en) 1998-12-10
JP4157177B2 (ja) 2008-09-24
US6417351B1 (en) 2002-07-09
KR100338787B1 (ko) 2002-05-31
EP0990656A4 (de) 2001-09-05
HK1027574A1 (en) 2001-01-19
DE69811074D1 (de) 2003-03-06
CN1098267C (zh) 2003-01-08
JPH10338694A (ja) 1998-12-22
AU7549998A (en) 1998-12-21
EP0990656A1 (de) 2000-04-05
KR20010013235A (ko) 2001-02-26
CN1257508A (zh) 2000-06-21
EP0990656B1 (de) 2003-01-29

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