ATE232100T1 - Gegen magensaft geschützte omeprazol- mikrogranülen, herstellungsverfahren und pharmazeutische zubereitungen - Google Patents

Gegen magensaft geschützte omeprazol- mikrogranülen, herstellungsverfahren und pharmazeutische zubereitungen

Info

Publication number
ATE232100T1
ATE232100T1 AT98942718T AT98942718T ATE232100T1 AT E232100 T1 ATE232100 T1 AT E232100T1 AT 98942718 T AT98942718 T AT 98942718T AT 98942718 T AT98942718 T AT 98942718T AT E232100 T1 ATE232100 T1 AT E232100T1
Authority
AT
Austria
Prior art keywords
production process
pharmaceutical preparations
protected against
stomach juice
omeprazole
Prior art date
Application number
AT98942718T
Other languages
English (en)
Inventor
Patrice Debregeas
Gerard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9522415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE232100(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Application granted granted Critical
Publication of ATE232100T1 publication Critical patent/ATE232100T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT98942718T 1998-01-30 1998-08-10 Gegen magensaft geschützte omeprazol- mikrogranülen, herstellungsverfahren und pharmazeutische zubereitungen ATE232100T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9801098A FR2774288B1 (fr) 1998-01-30 1998-01-30 Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques
PCT/FR1998/001783 WO1999038511A1 (fr) 1998-01-30 1998-08-10 Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques

Publications (1)

Publication Number Publication Date
ATE232100T1 true ATE232100T1 (de) 2003-02-15

Family

ID=9522415

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98942718T ATE232100T1 (de) 1998-01-30 1998-08-10 Gegen magensaft geschützte omeprazol- mikrogranülen, herstellungsverfahren und pharmazeutische zubereitungen

Country Status (31)

Country Link
US (1) US6551621B1 (de)
EP (1) EP1051174B2 (de)
JP (1) JP4286452B2 (de)
KR (1) KR100510366B1 (de)
CN (1) CN1114405C (de)
AT (1) ATE232100T1 (de)
AU (1) AU755882B2 (de)
BG (1) BG65087B1 (de)
BR (1) BR9814924B1 (de)
CA (1) CA2319015C (de)
CZ (1) CZ299192B6 (de)
DE (1) DE69811278T3 (de)
DK (1) DK1051174T4 (de)
EA (1) EA002879B1 (de)
EE (1) EE05620B1 (de)
ES (1) ES2189232T5 (de)
FR (1) FR2774288B1 (de)
GE (1) GEP20032941B (de)
HU (1) HU229956B1 (de)
IL (1) IL137536A0 (de)
IS (1) IS2866B (de)
NO (1) NO330144B1 (de)
NZ (1) NZ505998A (de)
PL (1) PL200043B1 (de)
PT (1) PT1051174E (de)
RS (1) RS50245B (de)
SI (1) SI1051174T2 (de)
SK (1) SK285666B6 (de)
TR (1) TR200002214T2 (de)
UA (1) UA61988C2 (de)
WO (1) WO1999038511A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
FR2793688B1 (fr) * 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
EP1603537A4 (de) * 2003-02-20 2009-11-04 Santarus Inc Neuartige formulierung, antazidkomplex-immediatfreisetzung für eine schnelle und anhaltende unterdrückung von magensäure
ES2234393B2 (es) * 2003-04-29 2006-09-01 Laboratorios Belmac, S.A. "formulaciones de pelets de compuestos bencimidazolicos antiulcerosos y labiles al acido".
JP2006528181A (ja) * 2003-07-18 2006-12-14 サンタラス インコーポレイティッド 酸分泌を阻害するために有用な薬学的製剤ならびにそれらを作製および使用する方法
JP2006528182A (ja) * 2003-07-18 2006-12-14 サンタラス インコーポレイティッド 薬学的製剤および酸に起因する消化器疾患の治療法
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
JP5171038B2 (ja) * 2003-10-10 2013-03-27 エティファルム イチョウ・エキスを含む放出持続性の微小顆粒およびそのような顆粒の製造方法
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
JP2007522217A (ja) * 2004-02-10 2007-08-09 サンタラス インコーポレイティッド プロトンポンプ阻害剤、緩衝剤および非ステロイド系抗炎症薬の組み合わせ
US20050239845A1 (en) * 2004-04-16 2005-10-27 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP1768668A2 (de) 2004-06-16 2007-04-04 Tap Pharmaceutical Products, Inc. Multi-ppi-dosierform
US20070154542A1 (en) * 2005-12-30 2007-07-05 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
HUE040311T2 (hu) 2006-04-04 2019-02-28 Kg Acquisition Llc Vérlemezke aggregációt gátló szert és sav inhibitort tartalmazó orális dózisformák
WO2007138606A2 (en) * 2006-06-01 2007-12-06 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
AU2007311493B2 (en) * 2006-10-17 2013-01-31 Ranbaxy Laboratories Limited Multiple unit tablet compositions of benzimidazole compounds
BR112014016085A8 (pt) 2011-12-28 2017-07-04 Pozen Inc composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
SMT202300083T1 (it) 2015-07-17 2023-05-12 Be Pharbel Mfg Microparticelle multistrato rilascianti composti farmaceuticamente attivi in una forma di dosaggio liquida
EP3117824A1 (de) 2015-07-17 2017-01-18 BE Pharbel Manufacturing Mehrschichtige mikropartikel zur freigabe einer pharmazeutisch aktiven verbindung in einer flüssigen verabreichungsform
US12472149B2 (en) 2015-07-17 2025-11-18 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
US10736855B2 (en) 2016-02-25 2020-08-11 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
FR3078630B1 (fr) 2018-03-08 2021-05-14 Karim Ioualalen Mode de formulation sous forme de solide divise hydrophobe

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
JPH0768125B2 (ja) * 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
EP0785984B1 (de) * 1994-09-30 2002-07-10 Medical Security Corporation Verfahren zum reinigen und rutschfesten behandlung von oberflächenbelägen
ES2094694B1 (es) † 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
CH687810A5 (de) 1995-05-24 1997-02-28 Mepha Ag Pelletformulierung mit Omeprazol.
CN1093855C (zh) * 1995-09-21 2002-11-06 帕斯医药股份有限公司 新的含有对酸不稳定的奥美拉唑的组合物及其制备方法
ZA979937B (en) * 1996-11-06 1999-05-18 Sharmatek Inc Delayed delivery system for acid-sensitive drugs
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
SE9704870D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II

Also Published As

Publication number Publication date
NO20004654L (no) 2000-09-18
EP1051174A1 (de) 2000-11-15
JP2002501895A (ja) 2002-01-22
CZ20002709A3 (cs) 2000-12-13
AU9074898A (en) 1999-08-16
IL137536A0 (en) 2001-07-24
DK1051174T4 (da) 2012-10-01
HUP0100347A3 (en) 2002-12-28
PT1051174E (pt) 2003-06-30
NO330144B1 (no) 2011-02-21
PL200043B1 (pl) 2008-11-28
BR9814924B1 (pt) 2010-07-13
GEP20032941B (en) 2003-04-25
EE200000466A (et) 2002-04-15
KR20010040502A (ko) 2001-05-15
DE69811278T3 (de) 2012-11-29
CN1114405C (zh) 2003-07-16
EA002879B1 (ru) 2002-10-31
WO1999038511A1 (fr) 1999-08-05
SI1051174T2 (sl) 2013-01-31
TR200002214T2 (tr) 2000-12-21
NO20004654D0 (no) 2000-09-18
ES2189232T3 (es) 2003-07-01
US6551621B1 (en) 2003-04-22
IS5577A (is) 2000-07-25
CA2319015A1 (fr) 1999-08-05
DE69811278D1 (de) 2003-03-13
HK1032354A1 (en) 2001-07-20
BG104634A (bg) 2001-02-28
EE05620B1 (et) 2013-02-15
SI1051174T1 (sl) 2003-06-30
EP1051174B1 (de) 2003-02-05
EA200000797A1 (ru) 2001-02-26
YU48400A (sh) 2003-02-28
BG65087B1 (bg) 2007-02-28
DK1051174T3 (da) 2003-05-26
NZ505998A (en) 2003-11-28
FR2774288A1 (fr) 1999-08-06
IS2866B (is) 2014-01-15
ES2189232T5 (es) 2012-11-07
HU229956B1 (hu) 2015-03-02
UA61988C2 (uk) 2003-12-15
EP1051174B2 (de) 2012-07-04
RS50245B (sr) 2009-07-15
AU755882B2 (en) 2003-01-02
HUP0100347A2 (hu) 2001-10-28
DE69811278T2 (de) 2003-11-27
FR2774288B1 (fr) 2001-09-07
SK11412000A3 (sk) 2001-04-09
CZ299192B6 (cs) 2008-05-14
KR100510366B1 (ko) 2005-08-24
PL342044A1 (en) 2001-05-21
CA2319015C (fr) 2008-08-05
SK285666B6 (sk) 2007-05-03
JP4286452B2 (ja) 2009-07-01
BR9814924A (pt) 2000-10-17
CN1284877A (zh) 2001-02-21

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