ATE232359T1 - Die beseitigung von sauerstoff beinhaltendes verfahren zur verlängerung der nutzbaren bevorratungszeit von gekühlten roten blutkörperchen - Google Patents

Die beseitigung von sauerstoff beinhaltendes verfahren zur verlängerung der nutzbaren bevorratungszeit von gekühlten roten blutkörperchen

Info

Publication number: ATE232359T1
Authority: AT; Austria
Prior art keywords: blood cells; red blood; extensing; method including; storage time
Prior art date: 1995-06-05

Application number

AT96918133T

Other languages

English (en)

Inventor

Mark W Bitensky

Tatsuro Yoshida

Original Assignee

Univ California

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-05

Filing date

1996-06-05

Publication date

2003-02-15

1996-06-05 Application filed by Univ California filed Critical Univ California

2003-02-15 Application granted granted Critical

2003-02-15 Publication of ATE232359T1 publication Critical patent/ATE232359T1/de

Links

210000003743 erythrocyte Anatomy 0.000 title abstract 4
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 3
239000001301 oxygen Substances 0.000 title abstract 3
229910052760 oxygen Inorganic materials 0.000 title abstract 3
230000008030 elimination Effects 0.000 title 1
238000003379 elimination reaction Methods 0.000 title 1
ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 abstract 2
ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 abstract 2
239000004254 Ammonium phosphate Substances 0.000 abstract 1
206010018910 Haemolysis Diseases 0.000 abstract 1
229910000148 ammonium phosphate Inorganic materials 0.000 abstract 1
235000019289 ammonium phosphates Nutrition 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 abstract 1
238000011010 flushing procedure Methods 0.000 abstract 1
230000008588 hemolysis Effects 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
239000011261 inert gas Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000012528 membrane Substances 0.000 abstract 1
238000004321 preservation Methods 0.000 abstract 1
230000004083 survival effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Dentistry (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT96918133T 1995-06-05 1996-06-05 Die beseitigung von sauerstoff beinhaltendes verfahren zur verlängerung der nutzbaren bevorratungszeit von gekühlten roten blutkörperchen ATE232359T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/473,675 US5624794A (en)	1995-06-05	1995-06-05	Method for extending the useful shelf-life of refrigerated red blood cells by flushing with inert gas
PCT/US1996/009005 WO1996039026A1 (en)	1995-06-05	1996-06-05	Method using oxygen removal for extending the useful shelf-life of refrigerated red blood cells

Publications (1)

Publication Number	Publication Date
ATE232359T1 true ATE232359T1 (de)	2003-02-15

Family

ID=23880537

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96918133T ATE232359T1 (de)	1995-06-05	1996-06-05	Die beseitigung von sauerstoff beinhaltendes verfahren zur verlängerung der nutzbaren bevorratungszeit von gekühlten roten blutkörperchen

Country Status (13)

Country	Link
US (1)	US5624794A (de)
EP (1)	EP0830058B1 (de)
JP (1)	JP4303786B2 (de)
KR (1)	KR100395033B1 (de)
CN (1)	CN1153512C (de)
AT (1)	ATE232359T1 (de)
AU (1)	AU710467B2 (de)
BR (1)	BR9608404A (de)
CA (1)	CA2223130C (de)
DE (1)	DE69626204T2 (de)
ES (1)	ES2194993T3 (de)
RU (1)	RU2181542C2 (de)
WO (1)	WO1996039026A1 (de)

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US7648699B2 (en) *	2000-06-02	2010-01-19	Caridianbct Biotechnologies, Llc	Preventing transfusion related complications in a recipient of a blood transfusion
TW590780B (en) *	2000-06-02	2004-06-11	Gambro Inc	Additive solutions containing riboflavin
US6548241B1 (en)	2000-11-28	2003-04-15	Gambro, Inc.	Storage solution containing photosensitizer for inactivation of biological contaminants
WO2003043571A2 (en) *	2001-11-16	2003-05-30	Hollinger Digital, Inc.	Method for extending the useful shelf-life of refrigerated red blood cells by nutrient supplementation
US20030124504A1 (en) *	2001-11-16	2003-07-03	Bitensky Mark W.	Additive solution for blood preservation
US8828226B2 (en)	2003-03-01	2014-09-09	The Trustees Of Boston University	System for assessing the efficacy of stored red blood cells using microvascular networks
US9314014B2 (en) *	2004-02-18	2016-04-19	University Of Maryland, Baltimore	Compositions and methods for the storage of red blood cells
CN1325518C (zh) *	2005-09-09	2007-07-11	李勇	人细胞膜抗原的保存方法及磁性粒子包被人细胞膜抗原
AU2007300585A1 (en) *	2006-09-21	2008-04-03	Kyphon Sarl	Diammonium phosphate and other ammonium salts and their use in preventing clotting
CN101868255A (zh) *	2007-08-01	2010-10-20	科安比司特生物技术有限责任公司	全血的病原体灭活
WO2009026073A1 (en) *	2007-08-22	2009-02-26	Caridianbct Biotechnologies, Llc	Prevention of transfusion related acute lung injury using riboflavin and light
US8968992B2 (en) *	2008-03-21	2015-03-03	Fenwal, Inc.	Red blood cell storage medium for extended storage
US8871434B2 (en) *	2008-03-21	2014-10-28	Fenwal, Inc.	Red blood cell storage medium for extended storage
US11284616B2 (en)	2010-05-05	2022-03-29	Hemanext Inc.	Irradiation of red blood cells and anaerobic storage
CN102905522A (zh) *	2009-10-12	2013-01-30	新健康科学股份有限公司	用于从红细胞中除去氧的氧消耗装置和方法
BR112012008683B8 (pt) *	2009-10-12	2022-11-08	Hemanext Inc	dispositivo de armazenagem de sangue para armazenar sangue depletado de oxigênio e dióxido de carbono, dispositivo de depleção de oxigênio e dióxido de carbono, método para remover oxigênio e dióxido de carbono de hemácias, sistema de armazenagem de sangue, dispositivo de armazenagem de sangue, método para remover oxigênio de hemácias e método para aumentar os níveis de adenosina trifosfato (atp) nas hemácias
US12089589B2 (en)	2009-10-12	2024-09-17	Hemanext Inc.	Irradiation of red blood cells and anaerobic storage
US9199016B2 (en)	2009-10-12	2015-12-01	New Health Sciences, Inc.	System for extended storage of red blood cells and methods of use
US11864553B2 (en)	2009-10-23	2024-01-09	Fenwal, Inc.	Methods and systems for providing red blood cell products with reduced plasma
WO2012027582A1 (en)	2010-08-25	2012-03-01	New Health Sciences	Method for enhancing red blood cell quality and survival during storage
EP4218412A1 (de)	2010-11-05	2023-08-02	Hemanext Inc.	Bestrahlung von roten blutkörperchen und anaerobe lagerung
CA2826969C (en)	2010-11-29	2019-02-19	New York Blood Center, Inc.	Method of blood pooling and storage
KR20140033015A (ko)	2011-03-16	2014-03-17	메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치	적혈구 조제물 및 혈소판 조제물의 유효 저장성을 연장하는 방법 및 물질
US9067004B2 (en)	2011-03-28	2015-06-30	New Health Sciences, Inc.	Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
CN103492041B (zh) *	2011-03-28	2017-02-08	新健康科学股份有限公司	用于在红细胞血液处理过程中使用惰性载气和歧管组件去除氧和二氧化碳的方法和系统
JP2014518283A (ja) *	2011-07-05	2014-07-28	ニュー・ヘルス・サイエンシーズ・インコーポレイテッド	赤血球の長期保存システムおよび使用方法
AU2012294269B2 (en)	2011-08-10	2016-11-24	Hemanext Inc.	Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
CA2860037C (en)	2011-09-26	2019-09-24	Advanced Preservations Technologies, Llc	Method for living tissue preservation
CA2874505C (en)	2012-05-22	2023-08-15	New Health Sciences, Inc.	Capillary network devices and methods of use
KR102101684B1 (ko) *	2012-11-30	2020-04-17	리치 테크놀로지스 홀딩 컴퍼니 엘엘씨	적혈구 보존 방법
CA2902061C (en)	2013-02-28	2023-08-08	New Health Sciences, Inc.	Gas depletion and gas addition devices for blood treatment
CN105246492B (zh) *	2014-03-13	2017-09-29	水株式会社	含氢生物体应用液的制造方法、及用于该制造方法的外包装体
KR20250033333A (ko)	2015-03-10	2025-03-07	헤마넥스트 인코포레이티드	산소 감소 1회용 키트, 장치 및 이의 사용 방법
BR122022005103B1 (pt)	2015-04-23	2023-03-14	Hemanext Inc	Dispositivo de armazenamento de sangue para armazenar sangue depletado de oxigênio e método para armazenar sangue depletado de oxigênio
PT3297641T (pt) *	2015-05-18	2025-10-09	Hemanext Inc	Métodos de armazenamento de sangue total e respetivas composições
CN109195632A (zh)	2016-05-27	2019-01-11	新健康科学股份有限公司	厌氧血液储存和病原体失活方法
CN109414542B (zh)	2016-06-23	2022-09-09	希玛奈克斯特股份有限公司	管理需要输血的患者群体中的不良事件的方法
EP3708174B1 (de)	2017-05-19	2022-10-12	Hemanext Inc.	Verfahren und behandlung von trauma
CN107873696B (zh) *	2017-11-14	2020-12-11	上海市血液中心	一种熊科动物红细胞保存液及其应用
CA3118792A1 (en)	2018-11-16	2020-05-22	Hemanext Inc.	Methods for managing adverse events in patients with inflammation
CN110447634A (zh) *	2019-06-27	2019-11-15	浙江省疾病预防控制中心	一种猴红细胞保存液及应用
CN110199987A (zh) *	2019-07-22	2019-09-06	深圳市未来细胞生命科技有限公司	一种间充质干细胞保存液及其保存方法和应用
CN114288484B (zh) *	2021-12-10	2023-01-03	中国人民解放军军事科学院军事医学研究院	低氧过滤血袋系统、血袋系统以及血液处理方法
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1995
- 1995-06-05 US US08/473,675 patent/US5624794A/en not_active Expired - Fee Related
1996
- 1996-06-05 JP JP50143097A patent/JP4303786B2/ja not_active Expired - Lifetime
- 1996-06-05 AU AU60470/96A patent/AU710467B2/en not_active Ceased
- 1996-06-05 AT AT96918133T patent/ATE232359T1/de not_active IP Right Cessation
- 1996-06-05 EP EP96918133A patent/EP0830058B1/de not_active Expired - Lifetime
- 1996-06-05 CA CA002223130A patent/CA2223130C/en not_active Expired - Lifetime
- 1996-06-05 BR BR9608404-9A patent/BR9608404A/pt not_active Application Discontinuation
- 1996-06-05 WO PCT/US1996/009005 patent/WO1996039026A1/en not_active Ceased
- 1996-06-05 CN CNB961960531A patent/CN1153512C/zh not_active Expired - Fee Related
- 1996-06-05 RU RU98100105/14A patent/RU2181542C2/ru active
- 1996-06-05 ES ES96918133T patent/ES2194993T3/es not_active Expired - Lifetime
- 1996-06-05 KR KR1019970708873A patent/KR100395033B1/ko not_active Expired - Fee Related
- 1996-06-05 DE DE69626204T patent/DE69626204T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0830058A1 (de)	1998-03-25
AU6047096A (en)	1996-12-24
RU2181542C2 (ru)	2002-04-27
ES2194993T3 (es)	2003-12-01
CA2223130A1 (en)	1996-12-12
DE69626204T2 (de)	2003-12-11
AU710467B2 (en)	1999-09-23
BR9608404A (pt)	1999-11-30
US5624794A (en)	1997-04-29
EP0830058A4 (de)	1999-04-14
EP0830058B1 (de)	2003-02-12
WO1996039026A1 (en)	1996-12-12
JP4303786B2 (ja)	2009-07-29
DE69626204D1 (de)	2003-03-20
CA2223130C (en)	2005-02-08
KR100395033B1 (ko)	2003-12-31
CN1153512C (zh)	2004-06-16
KR19990022393A (ko)	1999-03-25
CN1195965A (zh)	1998-10-14
JPH11506777A (ja)	1999-06-15

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2003-09-15

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Publication	Publication Date	Title
DE69626204D1 (de)	2003-03-20	Die beseitigung von sauerstoff beinhaltendes verfahren zur verlängerung der nutzbaren bevorratungszeit von gekühlten roten blutkörperchen
DE69633876D1 (de)	2004-12-23	Systeme und Methoden zur Trennung von Erythrocyten
EP0187816B1 (de)	1991-09-04	Verlängertes lagern roter blutzellen
Han et al.	1974	The Influence pH, Temperature, and Calcium on Platelet Aggregation: Maintenance of Environmental pH and Platelet Function for in Vitro Studies in Plasma Stored at 37° C
DE69901877D1 (de)	2002-07-25	Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation
RU98100105A (ru)	2000-01-27	Способ применения удаления кислорода для продления полезной сохранности охлажденных эритроцитов
DE3886006D1 (de)	1994-01-13	Synthetisches, plasmafreies, übertragbares Konservierungsmittel für rote Blutkörperchen.
DE3874019D1 (de)	1992-10-01	Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben.
ATE284448T1 (de)	2004-12-15	Verfahren zur kryoprotektion von zellen
DE69912457D1 (de)	2003-12-04	Verlängerte lagerung roter blutzellen
WO1995002326A1 (en)	1995-01-26	Solutions for tissue preservation and bloodless surgery and methods using same
AU8487998A (en)	1999-02-08	Novel apparatus and method for isolated pelvic perfusion
FR2523956B1 (de)	1985-05-24
NZ222051A (en)	1990-07-26	Solution containing adenosine or hypoxanthine and optionally ribose for heart protection during surgery
DE60213852D1 (de)	2006-09-21	Herstellung von zellsuspensionen
DE50307388D1 (de)	2007-07-12	Verfahren zur beschickung von probenkammern mit suspensionsproben
MX9709537A (es)	1998-03-31	Metodo que utiliza eliminacion de oxigeno para extender la vida util en anaquel de celulas sanguineas rojas refrigeradas.
Pillai et al.	1986	31P NMR spectroscopy of isolated perfused lungs
TR199900783T2 (xx)	1999-07-21	S-Alkilizotioronyum t�revlerini i�eren farmas�tik terkipler.
DE60034227D1 (de)	2007-05-16	Stabilisiertes denaturiertes lipoprotein und verfahren zu dessen herstellung
SU822799A1 (ru)	1981-04-23	Способ консервировани клеточ-НыХ СуСпЕНзий
SCHEIWE	1982	Investigations on the method of long term preservation of living blood cells by freezing[Ph. D. Thesis- Tech. Hochschule, Aachen]
Forester et al.	1989	31P NMR studies of the metabolic status of pig hearts preserved for transplantation
ATE230018T1 (de)	2003-01-15	Verfahren zur erzeugung, zum transport und zur eliminierung von biochemischen stoffen mittels aktiver biologischer zellen
Mil'chakov et al.	1995	Free-radical damage to the liver during its transplantation under conditions of oxidative stress