ES2194993T3 - Metodo que utiliza la extraccion de oxigeno para prolongar la vida util de eritrocitos refrigerados. - Google Patents

Metodo que utiliza la extraccion de oxigeno para prolongar la vida util de eritrocitos refrigerados.

Info

Publication number
ES2194993T3
ES2194993T3 ES96918133T ES96918133T ES2194993T3 ES 2194993 T3 ES2194993 T3 ES 2194993T3 ES 96918133 T ES96918133 T ES 96918133T ES 96918133 T ES96918133 T ES 96918133T ES 2194993 T3 ES2194993 T3 ES 2194993T3
Authority
ES
Spain
Prior art keywords
oxygen
erythrocytes
refrigerated
extraction
extend
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96918133T
Other languages
English (en)
Inventor
Mark W Bitensky
Tatsuro Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California, San Diego
Original Assignee
University of California Berkeley
University of California, San Diego
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California Berkeley, University of California, San Diego filed Critical University of California Berkeley
Application granted granted Critical
Publication of ES2194993T3 publication Critical patent/ES2194993T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO BARATO DE ALMACENAJE A 4 C QUE CONSERVA LA CALIDAD DE LOS GLOBULOS ROJOS Y PROLONGA LA SUPERVIVENCIA IN VIVO DESPUES DE UNA TRANSFUSION. SE CONSIGUE LA CONSERVACION DE LOS NIVELES DE ADENOSINA TRIFOSFATO Y LA REDUCCION DE LA HEMOLISIS Y DE LA PRODUCCION DE VESICULAS DE MEMBRANA DE GLOBULOS ROJOS ALMACENADOS A 4 DE TIEMPO, MEDIANTE LA ELIMINACION DEL OXIGENO DE ELLOS EN EL MOMENTO DEL ALMACENAJE. EN ALGUNAS MUESTRAS SE AUMENTAN LOS NIVELES DE ADENOSINA TRIFOSFATO DE LOS GLOBULOS ROJOS ALMACENADOS MEDIANTE LA ADICION DE FOSFATO DE AMONIO.
ES96918133T 1995-06-05 1996-06-05 Metodo que utiliza la extraccion de oxigeno para prolongar la vida util de eritrocitos refrigerados. Expired - Lifetime ES2194993T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/473,675 US5624794A (en) 1995-06-05 1995-06-05 Method for extending the useful shelf-life of refrigerated red blood cells by flushing with inert gas

Publications (1)

Publication Number Publication Date
ES2194993T3 true ES2194993T3 (es) 2003-12-01

Family

ID=23880537

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96918133T Expired - Lifetime ES2194993T3 (es) 1995-06-05 1996-06-05 Metodo que utiliza la extraccion de oxigeno para prolongar la vida util de eritrocitos refrigerados.

Country Status (13)

Country Link
US (1) US5624794A (es)
EP (1) EP0830058B1 (es)
JP (1) JP4303786B2 (es)
KR (1) KR100395033B1 (es)
CN (1) CN1153512C (es)
AT (1) ATE232359T1 (es)
AU (1) AU710467B2 (es)
BR (1) BR9608404A (es)
CA (1) CA2223130C (es)
DE (1) DE69626204T2 (es)
ES (1) ES2194993T3 (es)
RU (1) RU2181542C2 (es)
WO (1) WO1996039026A1 (es)

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US20030215784A1 (en) * 1998-07-21 2003-11-20 Dumont Larry Joe Method and apparatus for inactivation of biological contaminants using photosensitizers
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US7220747B2 (en) 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
US7985588B2 (en) * 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US7648699B2 (en) * 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US6548241B1 (en) 2000-11-28 2003-04-15 Gambro, Inc. Storage solution containing photosensitizer for inactivation of biological contaminants
WO2003043571A2 (en) * 2001-11-16 2003-05-30 Hollinger Digital, Inc. Method for extending the useful shelf-life of refrigerated red blood cells by nutrient supplementation
US20030124504A1 (en) * 2001-11-16 2003-07-03 Bitensky Mark W. Additive solution for blood preservation
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
US9314014B2 (en) * 2004-02-18 2016-04-19 University Of Maryland, Baltimore Compositions and methods for the storage of red blood cells
CN1325518C (zh) * 2005-09-09 2007-07-11 李勇 人细胞膜抗原的保存方法及磁性粒子包被人细胞膜抗原
AU2007300585A1 (en) * 2006-09-21 2008-04-03 Kyphon Sarl Diammonium phosphate and other ammonium salts and their use in preventing clotting
CN101868255A (zh) * 2007-08-01 2010-10-20 科安比司特生物技术有限责任公司 全血的病原体灭活
WO2009026073A1 (en) * 2007-08-22 2009-02-26 Caridianbct Biotechnologies, Llc Prevention of transfusion related acute lung injury using riboflavin and light
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
CN102905522A (zh) * 2009-10-12 2013-01-30 新健康科学股份有限公司 用于从红细胞中除去氧的氧消耗装置和方法
BR112012008683B8 (pt) * 2009-10-12 2022-11-08 Hemanext Inc dispositivo de armazenagem de sangue para armazenar sangue depletado de oxigênio e dióxido de carbono, dispositivo de depleção de oxigênio e dióxido de carbono, método para remover oxigênio e dióxido de carbono de hemácias, sistema de armazenagem de sangue, dispositivo de armazenagem de sangue, método para remover oxigênio de hemácias e método para aumentar os níveis de adenosina trifosfato (atp) nas hemácias
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
US11864553B2 (en) 2009-10-23 2024-01-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
WO2012027582A1 (en) 2010-08-25 2012-03-01 New Health Sciences Method for enhancing red blood cell quality and survival during storage
EP4218412A1 (en) 2010-11-05 2023-08-02 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
CA2826969C (en) 2010-11-29 2019-02-19 New York Blood Center, Inc. Method of blood pooling and storage
KR20140033015A (ko) 2011-03-16 2014-03-17 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 적혈구 조제물 및 혈소판 조제물의 유효 저장성을 연장하는 방법 및 물질
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
CN103492041B (zh) * 2011-03-28 2017-02-08 新健康科学股份有限公司 用于在红细胞血液处理过程中使用惰性载气和歧管组件去除氧和二氧化碳的方法和系统
JP2014518283A (ja) * 2011-07-05 2014-07-28 ニュー・ヘルス・サイエンシーズ・インコーポレイテッド 赤血球の長期保存システムおよび使用方法
AU2012294269B2 (en) 2011-08-10 2016-11-24 Hemanext Inc. Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
CA2860037C (en) 2011-09-26 2019-09-24 Advanced Preservations Technologies, Llc Method for living tissue preservation
CA2874505C (en) 2012-05-22 2023-08-15 New Health Sciences, Inc. Capillary network devices and methods of use
KR102101684B1 (ko) * 2012-11-30 2020-04-17 리치 테크놀로지스 홀딩 컴퍼니 엘엘씨 적혈구 보존 방법
CA2902061C (en) 2013-02-28 2023-08-08 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
CN105246492B (zh) * 2014-03-13 2017-09-29 水株式会社 含氢生物体应用液的制造方法、及用于该制造方法的外包装体
KR20250033333A (ko) 2015-03-10 2025-03-07 헤마넥스트 인코포레이티드 산소 감소 1회용 키트, 장치 및 이의 사용 방법
BR122022005103B1 (pt) 2015-04-23 2023-03-14 Hemanext Inc Dispositivo de armazenamento de sangue para armazenar sangue depletado de oxigênio e método para armazenar sangue depletado de oxigênio
PT3297641T (pt) * 2015-05-18 2025-10-09 Hemanext Inc Métodos de armazenamento de sangue total e respetivas composições
CN109195632A (zh) 2016-05-27 2019-01-11 新健康科学股份有限公司 厌氧血液储存和病原体失活方法
CN109414542B (zh) 2016-06-23 2022-09-09 希玛奈克斯特股份有限公司 管理需要输血的患者群体中的不良事件的方法
EP3708174B1 (en) 2017-05-19 2022-10-12 Hemanext Inc. Methods and treatment of trauma
CN107873696B (zh) * 2017-11-14 2020-12-11 上海市血液中心 一种熊科动物红细胞保存液及其应用
CA3118792A1 (en) 2018-11-16 2020-05-22 Hemanext Inc. Methods for managing adverse events in patients with inflammation
CN110447634A (zh) * 2019-06-27 2019-11-15 浙江省疾病预防控制中心 一种猴红细胞保存液及应用
CN110199987A (zh) * 2019-07-22 2019-09-06 深圳市未来细胞生命科技有限公司 一种间充质干细胞保存液及其保存方法和应用
CN114288484B (zh) * 2021-12-10 2023-01-03 中国人民解放军军事科学院军事医学研究院 低氧过滤血袋系统、血袋系统以及血液处理方法
EP4590312A1 (en) 2022-09-20 2025-07-30 Hemanext Inc. Oxygen reduced blood for use in the treatment of traumatic brain injury accompanied by hemorrhagic shock

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US4267269A (en) * 1980-02-05 1981-05-12 Baxter Travenol Laboratories, Inc. Red cell storage solution
DK185283A (da) * 1982-04-27 1983-10-28 Wellcome Found Tricycliske forbindelser, deres fremstilling og anvendelse, samt mellemprodukter herfor
DE3225408A1 (de) * 1982-07-07 1984-01-12 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Waessrige loesung zum suspendieren und lagern von zellen, insbesondere erythrozyten
US4585735A (en) * 1984-07-19 1986-04-29 American National Red Cross Prolonged storage of red blood cells
FR2581289A1 (fr) * 1985-05-06 1986-11-07 Rgl Transfusion Sanguine Centr Solution synthetique pour la conservation prolongee de concentres erythrocytaires
DE3722984A1 (de) * 1987-07-11 1989-01-19 Biotest Pharma Gmbh Waessrige loesung zum suspendieren und lagern von zellen, insbesondere erythrozyten
SU1718766A1 (ru) * 1990-01-30 1992-03-15 Ленинградский научно-исследовательский институт гематологии и переливания крови Способ консервировани эритроцитов крови
US5476764A (en) * 1994-09-16 1995-12-19 The Regents Of The University Of California Method using CO for extending the useful shelf-life of refrigerated red blood cells

Also Published As

Publication number Publication date
EP0830058A1 (en) 1998-03-25
AU6047096A (en) 1996-12-24
ATE232359T1 (de) 2003-02-15
RU2181542C2 (ru) 2002-04-27
CA2223130A1 (en) 1996-12-12
DE69626204T2 (de) 2003-12-11
AU710467B2 (en) 1999-09-23
BR9608404A (pt) 1999-11-30
US5624794A (en) 1997-04-29
EP0830058A4 (en) 1999-04-14
EP0830058B1 (en) 2003-02-12
WO1996039026A1 (en) 1996-12-12
JP4303786B2 (ja) 2009-07-29
DE69626204D1 (de) 2003-03-20
CA2223130C (en) 2005-02-08
KR100395033B1 (ko) 2003-12-31
CN1153512C (zh) 2004-06-16
KR19990022393A (ko) 1999-03-25
CN1195965A (zh) 1998-10-14
JPH11506777A (ja) 1999-06-15

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