ATE232731T1 - Verwendung der gensequenz eines promotors zur behandlung rheumatischer erkrankungen - Google Patents

Verwendung der gensequenz eines promotors zur behandlung rheumatischer erkrankungen

Info

Publication number
ATE232731T1
ATE232731T1 AT93923675T AT93923675T ATE232731T1 AT E232731 T1 ATE232731 T1 AT E232731T1 AT 93923675 T AT93923675 T AT 93923675T AT 93923675 T AT93923675 T AT 93923675T AT E232731 T1 ATE232731 T1 AT E232731T1
Authority
AT
Austria
Prior art keywords
promoter
gene sequence
rheumatic diseases
treat rheumatic
treat
Prior art date
Application number
AT93923675T
Other languages
English (en)
Inventor
Shunichi Shiozawa
Original Assignee
Shunichi Shiozawa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shunichi Shiozawa filed Critical Shunichi Shiozawa
Application granted granted Critical
Publication of ATE232731T1 publication Critical patent/ATE232731T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/13—Decoys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT93923675T 1993-10-29 1993-10-29 Verwendung der gensequenz eines promotors zur behandlung rheumatischer erkrankungen ATE232731T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1993/001581 WO1995011684A1 (en) 1993-10-29 1993-10-29 Antagonistic inhibitor against mesenchymal cell growth

Publications (1)

Publication Number Publication Date
ATE232731T1 true ATE232731T1 (de) 2003-03-15

Family

ID=14070618

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93923675T ATE232731T1 (de) 1993-10-29 1993-10-29 Verwendung der gensequenz eines promotors zur behandlung rheumatischer erkrankungen

Country Status (10)

Country Link
EP (1) EP0733370B1 (de)
KR (1) KR100306376B1 (de)
AT (1) ATE232731T1 (de)
AU (1) AU683626B2 (de)
CA (1) CA2175368C (de)
DE (1) DE69332702T2 (de)
DK (1) DK0733370T3 (de)
ES (1) ES2188597T3 (de)
PT (1) PT733370E (de)
WO (1) WO1995011684A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011687A1 (en) * 1993-10-29 1995-05-04 Dzau Victor J Therapeutic use of cis-element decoys in vivo
US7615538B2 (en) * 1993-10-29 2009-11-10 Shunichi Shiozawa Method for therapy of rheumatoid arthritis
CA2300328A1 (en) 1999-09-14 2001-03-14 Cardiogene Gentherap. Systeme Ag Modulating transcription of genes in vascular cells
DE29916160U1 (de) 1999-09-14 2000-03-09 Cardiogene Gentherapeutische Systeme AG, 40699 Erkrath Modulation der Transkription von Genen in vaskulären Zellen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006570A1 (en) * 1989-10-25 1991-05-16 The University Of Melbourne HYBRID Fc RECEPTOR MOLECULES
WO1991011535A1 (en) * 1990-01-30 1991-08-08 Childrens Hospital Of Los Angeles Inhibition of transcription by double-stranded oligonucleotides
WO1992007072A1 (en) * 1990-10-10 1992-04-30 La Jolla Cancer Research Foundation Method of inhibiting transcription utilizing nuclear receptors
CA2106386A1 (en) * 1991-04-18 1992-10-19 Barbara C. F. Chu Oligodeoxynucleotides and oligonucleotides useful as decoys for proteins which selectively bind to defined dna sequences
WO1993014768A1 (en) * 1992-01-27 1993-08-05 The Trustees Of The University Of Pennsylvania Methods and compositions for neutralizing intracellular nucleic acid-binding protein biological activity in a cell, including methods and compositions useful to regulate gene function

Also Published As

Publication number Publication date
DK0733370T3 (da) 2003-04-07
CA2175368C (en) 2004-07-20
WO1995011684A1 (en) 1995-05-04
PT733370E (pt) 2003-07-31
AU683626B2 (en) 1997-11-20
KR100306376B1 (ko) 2001-11-30
DE69332702D1 (de) 2003-03-27
DE69332702T2 (de) 2003-10-16
ES2188597T3 (es) 2003-07-01
KR960705576A (ko) 1996-11-08
EP0733370B1 (de) 2003-02-19
EP0733370A4 (de) 1999-12-29
AU5345294A (en) 1995-05-22
CA2175368A1 (en) 1995-05-04
EP0733370A1 (de) 1996-09-25

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