DK0733370T3 - Anvendelse af en genpromotorsekvens til behandling af rheumatiske sygdomme - Google Patents

Anvendelse af en genpromotorsekvens til behandling af rheumatiske sygdomme

Info

Publication number
DK0733370T3
DK0733370T3 DK93923675T DK93923675T DK0733370T3 DK 0733370 T3 DK0733370 T3 DK 0733370T3 DK 93923675 T DK93923675 T DK 93923675T DK 93923675 T DK93923675 T DK 93923675T DK 0733370 T3 DK0733370 T3 DK 0733370T3
Authority
DK
Denmark
Prior art keywords
treatment
promoter sequence
gene promoter
rheumatic diseases
tgagtca
Prior art date
Application number
DK93923675T
Other languages
Danish (da)
English (en)
Inventor
Shunichi Shiozawa
Original Assignee
Shunichi Shiozawa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shunichi Shiozawa filed Critical Shunichi Shiozawa
Application granted granted Critical
Publication of DK0733370T3 publication Critical patent/DK0733370T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/13Decoys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK93923675T 1993-10-29 1993-10-29 Anvendelse af en genpromotorsekvens til behandling af rheumatiske sygdomme DK0733370T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1993/001581 WO1995011684A1 (en) 1993-10-29 1993-10-29 Antagonistic inhibitor against mesenchymal cell growth

Publications (1)

Publication Number Publication Date
DK0733370T3 true DK0733370T3 (da) 2003-04-07

Family

ID=14070618

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93923675T DK0733370T3 (da) 1993-10-29 1993-10-29 Anvendelse af en genpromotorsekvens til behandling af rheumatiske sygdomme

Country Status (10)

Country Link
EP (1) EP0733370B1 (de)
KR (1) KR100306376B1 (de)
AT (1) ATE232731T1 (de)
AU (1) AU683626B2 (de)
CA (1) CA2175368C (de)
DE (1) DE69332702T2 (de)
DK (1) DK0733370T3 (de)
ES (1) ES2188597T3 (de)
PT (1) PT733370E (de)
WO (1) WO1995011684A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0732929B1 (de) * 1993-10-29 2008-05-14 The Brigham And Women's Hospital, Inc. Therapeutische verwendung von cis-element-fallen in vivo
US7615538B2 (en) * 1993-10-29 2009-11-10 Shunichi Shiozawa Method for therapy of rheumatoid arthritis
DE29916160U1 (de) 1999-09-14 2000-03-09 Cardiogene Gentherapeutische Systeme AG, 40699 Erkrath Modulation der Transkription von Genen in vaskulären Zellen
CA2300328A1 (en) 1999-09-14 2001-03-14 Cardiogene Gentherap. Systeme Ag Modulating transcription of genes in vascular cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006570A1 (en) * 1989-10-25 1991-05-16 The University Of Melbourne HYBRID Fc RECEPTOR MOLECULES
WO1991011535A1 (en) * 1990-01-30 1991-08-08 Childrens Hospital Of Los Angeles Inhibition of transcription by double-stranded oligonucleotides
EP0552302A4 (en) * 1990-10-10 1993-11-10 La Jolla Cancer Research Foundation Method of inhibiting transcription utilizing nuclear receptors
EP0580754A1 (de) * 1991-04-18 1994-02-02 The Salk Institute For Biological Studies Oligodeoxynukleotide und oligonukleotide, verwendbar als köder für proteine, die ausgewählt zu definierten dns-sequenzen binden
AU3584993A (en) * 1992-01-27 1993-09-01 Trustees Of The University Of Pennsylvania, The Methods and compositions for neutralizing intracellular nucleic acid-binding protein biological activity in a cell, including methods and compositions useful to regulate gene function

Also Published As

Publication number Publication date
AU5345294A (en) 1995-05-22
CA2175368A1 (en) 1995-05-04
AU683626B2 (en) 1997-11-20
ATE232731T1 (de) 2003-03-15
DE69332702D1 (de) 2003-03-27
DE69332702T2 (de) 2003-10-16
PT733370E (pt) 2003-07-31
KR100306376B1 (ko) 2001-11-30
EP0733370A1 (de) 1996-09-25
ES2188597T3 (es) 2003-07-01
WO1995011684A1 (en) 1995-05-04
KR960705576A (ko) 1996-11-08
CA2175368C (en) 2004-07-20
EP0733370B1 (de) 2003-02-19
EP0733370A4 (de) 1999-12-29

Similar Documents

Publication Publication Date Title
DK1584682T3 (da) Regulering af bcl-2 gene ekspression
DE69434663D1 (de) Nukleotid-sequenzen zur kontrolle der exprimierung von dns-sequenzen in einem zellulärem wirt
DK0544894T3 (da) Anvendelse af exo-prøve-nukleotider i genkloning
DK0983370T3 (da) Inhibering af genekspression
DK1061805T3 (da) Regulering af den endogene genekspression i celler ved anvendelse af zinkfingerproteiner
DK0691980T3 (da) 7-deazapurinmodifiderende oligonukleotider
DK1411118T3 (da) Celleproliferationsinhibitorer indeholdende anti-glypican-3-antistof
DK0713529T3 (da) Vækst-/differentieringsfaktor af TGF-beta-familien
FI893962A7 (fi) HIV-proteaasi-inhibiittoreita, jotka ovat hyödyllisiä AIDS:in hoidossa
DK0658198T3 (da) Multicistroniske ekspressionsenheder samt deres anvendelse
FI935778A7 (fi) HIV-proteaasin inhibiittoreita, jotka ovat hyödyllisiä AIDSin hoitoa varten
ES2175244T3 (es) Empleo de acido poliasparaginico y de sus sales.
DE68908835D1 (de) Bioreaktor.
ATE255632T1 (de) Immortalisierung bzw. desimmortalisierung von zellen
MX9204375A (es) Gen activador para la biosintesis de macrolidos.
NO910982L (no) Uratoksydase-aktivt protein, rekombinant gen som koder for det, ekspresjonsvektor, mikroorganismer og transformerteceller.
ES2089687T3 (es) 4-fenil-piridonas y 4-fenil-2-alcoxipiridinas sustituidas como inhibidores de la hmg-coa-reductasa.
BR9006855A (pt) Proteina de atividade urato oxidase,gene recombinante que a codifica,vetor de expressao,microorganismos e celulas transformadas
FI935779L (fi) HIV-proteaasin inhibiittoreita, jotka ovat hyödyllisiä AIDSin hoitoa varten
ATE310082T1 (de) Pflanzenpromoter und dessen verwendung zur genexpression
DK0734380T3 (da) 4-Benzoylisoxazoler samt deres anvendelse som herbicider
ES2188597T3 (es) Uso de una secuencia genica promotora para el tratamiento de enfermedades reumaticas.
FI940912A0 (fi) Synteettiset t-RNA:t
DE69033756D1 (de) Gene, die für MACIF Proteine kodieren, Expressionsvektoren mit diesem Genen, und Transformantenzellen mit diesem Proteinen
DK0678096T3 (da) Syntese af dimerblokke og deres anvendelse til aggregering af oligonukleotider