ATE233098T1 - Kombination eines somatostatin analogs und eines rapamycins - Google Patents

Kombination eines somatostatin analogs und eines rapamycins

Info

Publication number: ATE233098T1
Authority: AT; Austria
Prior art keywords: combination; rapamycin; somatostatin analog; somatostatin; analog
Prior art date: 1996-06-11

Application number

AT97928175T

Other languages

English (en)

Inventor

Gisbert Weckbecker

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-11

Filing date

1997-06-11

Publication date

2003-03-15

1996-06-11 Priority claimed from GBGB9612171.0A external-priority patent/GB9612171D0/en

1996-09-16 Priority claimed from GBGB9619310.7A external-priority patent/GB9619310D0/en

1997-06-11 Application filed by Novartis Ag filed Critical Novartis Ag

2003-03-15 Application granted granted Critical

2003-03-15 Publication of ATE233098T1 publication Critical patent/ATE233098T1/de

Links

ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 title abstract 2
QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title abstract 2
229960002930 sirolimus Drugs 0.000 title abstract 2
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT97928175T 1996-06-11 1997-06-11 Kombination eines somatostatin analogs und eines rapamycins ATE233098T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9612171.0A GB9612171D0 (en)	1996-06-11	1996-06-11	Organic compounds
GBGB9619310.7A GB9619310D0 (en)	1996-09-16	1996-09-16	Organic compounds
PCT/EP1997/003036 WO1997047317A1 (en)	1996-06-11	1997-06-11	Combination of a somatostatin analogue and a rapamycin

Publications (1)

Publication Number	Publication Date
ATE233098T1 true ATE233098T1 (de)	2003-03-15

Family

ID=26309485

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97928175T ATE233098T1 (de)	1996-06-11	1997-06-11	Kombination eines somatostatin analogs und eines rapamycins

Country Status (10)

Country	Link
US (1)	US6362164B1 (de)
EP (1)	EP0896544B1 (de)
JP (1)	JP3784418B2 (de)
AT (1)	ATE233098T1 (de)
AU (1)	AU3257297A (de)
CA (1)	CA2249439C (de)
DE (1)	DE69719320T2 (de)
DK (1)	DK0896544T3 (de)
ES (1)	ES2193379T3 (de)
WO (1)	WO1997047317A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2368431C (en)	1999-03-29	2006-01-24	The Procter & Gamble Company	Melanocortin receptor ligands
ES2167189B1 (es) *	1999-12-17	2003-04-01	Lipotec Sa	Formulacion farmaceutica estable para la administracion intravenosa o intramuscular, de principios activos peptidicos
EP1250135B1 (de)	2000-01-14	2010-07-28	The Trustees of The University of Pennsylvania	O-methylierte rapamycinderivate zur milderung oder vermeidung lymphoproliferativer erkrankungen
AU2016206379B2 (en) *	2001-02-19	2017-09-14	Novartis Ag	Cancer Treatment
MX368013B (es)	2001-02-19	2019-09-13	Novartis Ag	Tratamiento de cáncer.
AU2005201004A1 (en) *	2001-02-19	2005-03-24	Novartis Ag	Cancer treatment
AU2011226833B9 (en) *	2001-02-19	2014-07-03	Novartis Ag	Cancer treatment
FI20031454A0 (fi)	2003-10-06	2003-10-06	Juvantia Pharma Ltd Oy	Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja
EP1522311A1 (de) *	2003-10-10	2005-04-13	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Verwendung von Somatostatin oder seine Derivate zur Herstellung eines Medikamentes zur Regulierung der Ovarialfollikelnreserve bei der nicht menopausierte Frau
CN1946852A (zh) *	2004-04-27	2007-04-11	惠氏公司	利用雷帕霉素特异性甲基化酶标记雷帕霉素
WO2006115509A2 (en)	2004-06-24	2006-11-02	Novartis Vaccines And Diagnostics Inc.	Small molecule immunopotentiators and assays for their detection
ES2383303T3 (es)	2005-11-10	2012-06-20	Chemi S.P.A.	Formulaciones de inhibidores de la liberación prolongada de la hormona del crecimiento análogos de la somatostatina
NO20220050A1 (no)	2005-11-21	2008-08-12	Novartis Ag	Neuroendokrin tumorbehandling
JP2009254391A (ja) *	2006-07-18	2009-11-05	Tetsuhiko Katsumata	ゴルフのボールマーカー用ホルダー及びアクセサリー
CN103037735B (zh)	2010-07-29	2016-06-01	利纳克有限公司	优选用于高度可调节桌的升降柱
PL2729008T3 (pl) *	2011-07-07	2017-10-31	Res Cancer Institute Of America	Systemy, sposoby i formulacje do leczenia raka
US8933078B2 (en)	2011-07-14	2015-01-13	Research Cancer Institute Of America	Method of treating cancer with combinations of histone deacetylase inhibitors (HDAC1) substances
US11890292B2 (en)	2017-02-27	2024-02-06	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
WO2018170457A1 (en)	2017-03-17	2018-09-20	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
US12213958B2 (en)	2017-11-17	2025-02-04	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
JP7099717B2 (ja)	2019-09-30	2022-07-12	株式会社理研バイオ	ソマトスタチン受容体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2239178B (en)	1987-07-10	1991-11-27	Sandoz Ltd	Somatostatin analogues for the treatment of breast cancer
GB9125660D0 (en) *	1991-12-03	1992-01-29	Smithkline Beecham Plc	Novel compound

1997
- 1997-06-11 AT AT97928175T patent/ATE233098T1/de active
- 1997-06-11 ES ES97928175T patent/ES2193379T3/es not_active Expired - Lifetime
- 1997-06-11 WO PCT/EP1997/003036 patent/WO1997047317A1/en not_active Ceased
- 1997-06-11 CA CA002249439A patent/CA2249439C/en not_active Expired - Lifetime
- 1997-06-11 DK DK97928175T patent/DK0896544T3/da active
- 1997-06-11 JP JP50120398A patent/JP3784418B2/ja not_active Expired - Lifetime
- 1997-06-11 US US09/194,957 patent/US6362164B1/en not_active Expired - Lifetime
- 1997-06-11 AU AU32572/97A patent/AU3257297A/en not_active Abandoned
- 1997-06-11 DE DE69719320T patent/DE69719320T2/de not_active Expired - Lifetime
- 1997-06-11 EP EP97928175A patent/EP0896544B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US6362164B1 (en)	2002-03-26
DE69719320D1 (de)	2003-04-03
EP0896544B1 (de)	2003-02-26
ES2193379T3 (es)	2003-11-01
EP0896544A1 (de)	1999-02-17
JP3784418B2 (ja)	2006-06-14
DE69719320T2 (de)	2003-12-11
WO1997047317A1 (en)	1997-12-18
JP2000514415A (ja)	2000-10-31
DK0896544T3 (da)	2003-05-05
CA2249439C (en)	2009-09-08
CA2249439A1 (en)	1997-12-18
AU3257297A (en)	1998-01-07

Legal Events

Date

Code

Title

Description

2003-09-15

UEP

Publication of translation of european patent specification

Ref document number: 0896544

Country of ref document: EP

Publication	Publication Date	Title
DE69719320D1 (de)	2003-04-03	Kombination eines somatostatin analogs und eines rapamycins
DE69410478D1 (de)	1998-06-25	Wasserdichter und wasserdampfdurchlässige abdeckung für körperschutz
TR199701567T1 (xx)	1998-04-21	Rapamisin t�revleri.
PT914103E (pt)	2006-09-29	Tratamento de uma hemoglobinopatia
DE69303214D1 (de)	1996-07-25	Zusammensetzungen und Methoden zur Gaslochbehandlung
ES2421455T3 (es)	2013-09-02	Uso de derivados de rapamicina en vasculopatías
EP0661098A3 (de)	1996-09-11	Abgasreinigung.
FI943396L (fi)	1994-07-15	Synteettisiä peptidejä bakteeriendotoksiinien myrkyttömäksi tekemistä ja septisen shokin hoitoa varten
HUP9903166A3 (en)	2003-09-29	Medicinal compositions for the prophylaxis or treatment of arteriosclerosis
FI942660L (fi)	1994-12-09	Actinoplanes sp:stä olevia lipopeptidejä, joilla on farmakologista vaikutusta, menetelmä niiden valmistamiseksi ja niiden käyttö
IL117656A0 (en)	1996-07-23	Pharmaceutical compositions for the treatment of travellers diarrhea
FI953483A7 (fi)	1995-09-15	Jätekaasuöljyn käsittely
GB2380939B (en)	2003-09-10	Treatment or prevention of auto-immune diseases
NO940318L (no)	1994-03-02	Anordning for behandling av eksosgass
EP0828520A4 (de)	2002-09-25	Verfahren zum screening von verbindungen, die zur prävention von infektionen oder der pathogenität
IL117655A0 (en)	1996-07-23	Pharmaceutical compositions for the treatment of travellers diarrhea
DE69535697D1 (de)	2008-03-20	Dihydrobenzofurane und verwandte verbindungen als entzündungshemmende mittel
BR9703240A (pt)	1999-05-11	Estabilização de peróxidos orgânicos com compostos b-dicarbonila ou &-dicetona cíclica
AU1979397A (en)	1997-09-16	Peptidomimetics for the treatment of hiv infection
GB9222590D0 (en)	1992-12-09	The treatment of solid organic wastes
KR950033598U (ko)	1995-12-16	스로틀 보디의 카본퇴적 방지장치
KR940022660U (ko)	1994-10-20	유기물 발효기용 탈취장치
LTIP1423A (en)	1995-05-25	Device for treatment of gullet stricture
ECSP961769A (es)	1997-10-03	Derivados de rapamicina
BR9202934A (pt)	1994-02-01	Registro de gas deslizante