DK0896544T3 - Kombination af en somatostatinanalog og en rapamycin - Google Patents

Kombination af en somatostatinanalog og en rapamycin

Info

Publication number: DK0896544T3
Authority: DK; Denmark
Prior art keywords: combination; rapamycin; somatostatin analogue; somatostatin; analogue
Prior art date: 1996-06-11

Application number

DK97928175T

Other languages

English (en)

Inventor

Gisbert Weckbecker

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-11

Filing date

1997-06-11

Publication date

2003-05-05

1996-06-11 Priority claimed from GBGB9612171.0A external-priority patent/GB9612171D0/en

1996-09-16 Priority claimed from GBGB9619310.7A external-priority patent/GB9619310D0/en

1997-06-11 Application filed by Novartis Ag filed Critical Novartis Ag

2003-05-05 Application granted granted Critical

2003-05-05 Publication of DK0896544T3 publication Critical patent/DK0896544T3/da

Links

ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 title abstract 2
QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title abstract 2
229960002930 sirolimus Drugs 0.000 title abstract 2
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 2
229940075620 somatostatin analogue Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK97928175T 1996-06-11 1997-06-11 Kombination af en somatostatinanalog og en rapamycin DK0896544T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9612171.0A GB9612171D0 (en)	1996-06-11	1996-06-11	Organic compounds
GBGB9619310.7A GB9619310D0 (en)	1996-09-16	1996-09-16	Organic compounds
PCT/EP1997/003036 WO1997047317A1 (en)	1996-06-11	1997-06-11	Combination of a somatostatin analogue and a rapamycin

Publications (1)

Publication Number	Publication Date
DK0896544T3 true DK0896544T3 (da)	2003-05-05

Family

ID=26309485

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97928175T DK0896544T3 (da)	1996-06-11	1997-06-11	Kombination af en somatostatinanalog og en rapamycin

Country Status (10)

Country	Link
US (1)	US6362164B1 (da)
EP (1)	EP0896544B1 (da)
JP (1)	JP3784418B2 (da)
AT (1)	ATE233098T1 (da)
AU (1)	AU3257297A (da)
CA (1)	CA2249439C (da)
DE (1)	DE69719320T2 (da)
DK (1)	DK0896544T3 (da)
ES (1)	ES2193379T3 (da)
WO (1)	WO1997047317A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100558131B1 (ko)	1999-03-29	2006-03-10	더 프록터 앤드 갬블 캄파니	멜라노코르틴 수용체 리간드를 함유하는 약제학적 조성물및 멜라노코르틴 수용체 리간드를 함유하는 약제의제조방법
ES2167189B1 (es) *	1999-12-17	2003-04-01	Lipotec Sa	Formulacion farmaceutica estable para la administracion intravenosa o intramuscular, de principios activos peptidicos
ATE475418T1 (de) *	2000-01-14	2010-08-15	Univ Pennsylvania	O-methylierte rapamycinderivate zur milderung oder vermeidung lymphoproliferativer erkrankungen
DK3351246T3 (da) *	2001-02-19	2019-06-03	Novartis Pharma Ag	Rapamycinderivat til behandling af en solid tumor, som er associeret med dereguleret angionese
AU2005201004A1 (en) *	2001-02-19	2005-03-24	Novartis Ag	Cancer treatment
AU2011226833B9 (en) *	2001-02-19	2014-07-03	Novartis Ag	Cancer treatment
AU2016206379B2 (en) *	2001-02-19	2017-09-14	Novartis Ag	Cancer Treatment
FI20031454A0 (fi)	2003-10-06	2003-10-06	Juvantia Pharma Ltd Oy	Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja
EP1522311A1 (fr) *	2003-10-10	2005-04-13	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée
MXPA06012404A (es) *	2004-04-27	2007-01-17	Wyeth Corp	Marcado de rapamicina usando metilasas especificas de rapamicina.
EP1768662A2 (en)	2004-06-24	2007-04-04	Novartis Vaccines and Diagnostics, Inc.	Small molecule immunopotentiators and assays for their detection
PT1787658E (pt)	2005-11-10	2012-06-22	Chemi Spa	Formulações de libertação sustentada de análogos de somatostatina inibidores da hormona do crescimento
ES2481671T3 (es) *	2005-11-21	2014-07-31	Novartis Ag	Inhibidores de mTOR en el tratamiento de tumores endocrinos
JP2009254391A (ja) *	2006-07-18	2009-11-05	Tetsuhiko Katsumata	ゴルフのボールマーカー用ホルダー及びアクセサリー
WO2012013190A2 (en)	2010-07-29	2012-02-02	Linak A/S	Lifting column preferably for height-adjustable tables
RU2644635C2 (ru) *	2011-07-07	2018-02-13	Рисёрч Кансер Инститьют Оф Америка	Системы, способы и составы для лечения рака
US8933078B2 (en)	2011-07-14	2015-01-13	Research Cancer Institute Of America	Method of treating cancer with combinations of histone deacetylase inhibitors (HDAC1) substances
US11890292B2 (en)	2017-02-27	2024-02-06	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
US11369585B2 (en)	2017-03-17	2022-06-28	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
WO2019099750A1 (en)	2017-11-17	2019-05-23	Research Cancer Institute Of America	Compositions, methods, systems and/or kits for preventing and/or treating neoplasms
JP7099717B2 (ja)	2019-09-30	2022-07-12	株式会社理研バイオ	ソマトスタチン受容体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2239178B (en)	1987-07-10	1991-11-27	Sandoz Ltd	Somatostatin analogues for the treatment of breast cancer
GB9125660D0 (en) *	1991-12-03	1992-01-29	Smithkline Beecham Plc	Novel compound

1997
- 1997-06-11 ES ES97928175T patent/ES2193379T3/es not_active Expired - Lifetime
- 1997-06-11 WO PCT/EP1997/003036 patent/WO1997047317A1/en not_active Ceased
- 1997-06-11 DK DK97928175T patent/DK0896544T3/da active
- 1997-06-11 AT AT97928175T patent/ATE233098T1/de active
- 1997-06-11 US US09/194,957 patent/US6362164B1/en not_active Expired - Lifetime
- 1997-06-11 DE DE69719320T patent/DE69719320T2/de not_active Expired - Lifetime
- 1997-06-11 CA CA002249439A patent/CA2249439C/en not_active Expired - Lifetime
- 1997-06-11 EP EP97928175A patent/EP0896544B1/en not_active Expired - Lifetime
- 1997-06-11 JP JP50120398A patent/JP3784418B2/ja not_active Expired - Lifetime
- 1997-06-11 AU AU32572/97A patent/AU3257297A/en not_active Abandoned

Also Published As

Publication number	Publication date
EP0896544A1 (en)	1999-02-17
JP3784418B2 (ja)	2006-06-14
ES2193379T3 (es)	2003-11-01
DE69719320D1 (de)	2003-04-03
ATE233098T1 (de)	2003-03-15
JP2000514415A (ja)	2000-10-31
DE69719320T2 (de)	2003-12-11
EP0896544B1 (en)	2003-02-26
CA2249439C (en)	2009-09-08
WO1997047317A1 (en)	1997-12-18
AU3257297A (en)	1998-01-07
US6362164B1 (en)	2002-03-26
CA2249439A1 (en)	1997-12-18

Publication	Publication Date	Title
DK0896544T3 (da)	2003-05-05	Kombination af en somatostatinanalog og en rapamycin
BR9708601A (pt)	1999-08-03	Tratamento de uma hemoglobinopatia
DE69306024D1 (de)	1997-01-02	Klärschlammaufbereitung
ATE206413T1 (de)	2001-10-15	Substituierte oxazolidine als calpain und/oder cathepsin b-hemmer
ES2191830T3 (es)	2003-09-16	Inhibidores de trombina.
DE59608538D1 (de)	2002-02-07	Bohr- und/oder Meisselgerät
NO305398B1 (no)	1999-05-25	Tiosubstituerte nitrogenholdige heterocykliske fosfonatforbindelser, og anvendelser derav
FI953483A0 (fi)	1995-07-18	Jätekaasuöljyn käsittely
FI945355L (fi)	1995-05-17	Läpivienti
KR950704653A (ko)	1995-11-20	독성 폐기물의 처리(treatment of toxic wastes)
DK206391A (da)	1993-06-30	Slambehandling
ATE228760T1 (de)	2002-12-15	Thrombininhibitoren
DE59711737D1 (de)	2004-08-05	Gewölbtes Metall-Keramik-Substrat
FI1215U1 (fi)	1994-02-21	Anlaeggning i samband med styrningen av en vira
FI943344A7 (fi)	1995-01-15	Urinaali
DE59812757D1 (de)	2005-06-02	Substituierte tetrahydro-naphtaline und analoge verbindungen
NO961619D0 (no)	1996-04-23	Spylekammer
FR2711511B1 (fr)	1996-01-26	Prothèses métatarso-phalangiennes temporaires.
KR950003749U (ko)	1995-02-17	폐수 처리기
FI94161B (fi)	1995-04-13	Luukkurakenne
KR950003750U (ko)	1995-02-17	폐수 처리기
KR950012058U (ko)	1995-05-16	다단식 소각장치
KR940026912U (ko)	1994-12-09	하수관
KR940019393U (ko)	1994-08-19	하수관
KR940022789U (ko)	1994-10-20	악취가스 역류방지 배수구