ATE233315T1 - Produktionsmethoden für herpes simplex virus 1 oder 2 protease - Google Patents

Produktionsmethoden für herpes simplex virus 1 oder 2 protease

Info

Publication number
ATE233315T1
ATE233315T1 AT95927255T AT95927255T ATE233315T1 AT E233315 T1 ATE233315 T1 AT E233315T1 AT 95927255 T AT95927255 T AT 95927255T AT 95927255 T AT95927255 T AT 95927255T AT E233315 T1 ATE233315 T1 AT E233315T1
Authority
AT
Austria
Prior art keywords
protease
herpes simplex
simplex virus
production methods
resulting
Prior art date
Application number
AT95927255T
Other languages
English (en)
Inventor
Paul L Darke
Dawn L Hall
Lawrence C Kuo
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE233315T1 publication Critical patent/ATE233315T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT95927255T 1994-07-21 1995-07-17 Produktionsmethoden für herpes simplex virus 1 oder 2 protease ATE233315T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/279,754 US5486470A (en) 1994-07-21 1994-07-21 Purified herpes simplex virus protease and methods of purification
PCT/US1995/009052 WO1996003498A1 (en) 1994-07-21 1995-07-17 Purified herpes simplex virus protease and methods of purification

Publications (1)

Publication Number Publication Date
ATE233315T1 true ATE233315T1 (de) 2003-03-15

Family

ID=23070306

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95927255T ATE233315T1 (de) 1994-07-21 1995-07-17 Produktionsmethoden für herpes simplex virus 1 oder 2 protease

Country Status (8)

Country Link
US (1) US5486470A (de)
EP (1) EP0777727B1 (de)
JP (1) JPH10503648A (de)
AT (1) ATE233315T1 (de)
CA (1) CA2193851A1 (de)
DE (1) DE69529754T2 (de)
ES (1) ES2191709T3 (de)
WO (1) WO1996003498A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083711A (en) * 1996-05-15 2000-07-04 Smithkline Beecham Corporation Proteases compositions capable of binding to said site, and methods of use thereof
US5965358A (en) * 1998-08-26 1999-10-12 Genvec, Inc. Method for assessing the relative purity of viral gene transfer vector stocks
US7704958B1 (en) 1999-03-05 2010-04-27 Bio Holding, Inc. Methods and compositions for inhibiting apoptosis using serine protease inhibitors
AU3511500A (en) 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
US6849605B1 (en) 1999-03-05 2005-02-01 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
WO2000051625A1 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses
ITBO20010426A1 (it) * 2001-07-06 2003-01-06 Alfa Wassermann Spa Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico
US20040220242A1 (en) * 2003-05-02 2004-11-04 Leland Shapiro Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
US20130156884A1 (en) * 2011-12-19 2013-06-20 Triarco Industries Protease enzymes for increased protein digestion rate and absorption and methods of using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ242739A (en) * 1991-05-24 1994-12-22 Arch Dev Corp Identification and purification of herpes protease nucleic acid segments and their use in the production of this protease
US5434074A (en) * 1991-07-05 1995-07-18 Gibson; D. Wade Cytomegalovirus proteinase

Also Published As

Publication number Publication date
CA2193851A1 (en) 1996-02-08
WO1996003498A1 (en) 1996-02-08
JPH10503648A (ja) 1998-04-07
EP0777727B1 (de) 2003-02-26
US5486470A (en) 1996-01-23
EP0777727A4 (de) 1999-01-27
DE69529754D1 (de) 2003-04-03
ES2191709T3 (es) 2003-09-16
EP0777727A1 (de) 1997-06-11
DE69529754T2 (de) 2003-10-16

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Legal Events

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