ATE234083T1 - Verwendung von aminoadamantan-verbindungen als immunregulatoren - Google Patents

Verwendung von aminoadamantan-verbindungen als immunregulatoren

Info

Publication number
ATE234083T1
ATE234083T1 AT96930065T AT96930065T ATE234083T1 AT E234083 T1 ATE234083 T1 AT E234083T1 AT 96930065 T AT96930065 T AT 96930065T AT 96930065 T AT96930065 T AT 96930065T AT E234083 T1 ATE234083 T1 AT E234083T1
Authority
AT
Austria
Prior art keywords
compounds
aminoadamantan
immune regulators
aminoadamantane
neutrophils
Prior art date
Application number
AT96930065T
Other languages
English (en)
Inventor
Erich F Elstner
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Application granted granted Critical
Publication of ATE234083T1 publication Critical patent/ATE234083T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/064—Saccharomycetales, e.g. baker's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT96930065T 1995-08-25 1996-08-21 Verwendung von aminoadamantan-verbindungen als immunregulatoren ATE234083T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19531342A DE19531342B4 (de) 1995-08-25 1995-08-25 Verwendung von Aminoadamantan-Verbindungen als Immunregulatoren
PCT/EP1996/003678 WO1997007791A1 (en) 1995-08-25 1996-08-21 Use of aminoadamantane compounds as immunoregulators

Publications (1)

Publication Number Publication Date
ATE234083T1 true ATE234083T1 (de) 2003-03-15

Family

ID=7770407

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96930065T ATE234083T1 (de) 1995-08-25 1996-08-21 Verwendung von aminoadamantan-verbindungen als immunregulatoren

Country Status (21)

Country Link
US (2) US6172116B1 (de)
EP (2) EP0845984B1 (de)
JP (1) JPH11512093A (de)
KR (1) KR100392986B1 (de)
CN (1) CN1282452C (de)
AT (1) ATE234083T1 (de)
AU (1) AU718219B2 (de)
CA (1) CA2230159C (de)
CZ (1) CZ299356B6 (de)
DE (3) DE19531342B4 (de)
DK (1) DK0845984T3 (de)
EE (1) EE04261B1 (de)
ES (1) ES2193259T3 (de)
GE (1) GEP19991779B (de)
IL (1) IL123394A (de)
MX (1) MX217078B (de)
NO (1) NO319153B1 (de)
RU (1) RU2219916C2 (de)
UA (1) UA57711C2 (de)
WO (1) WO1997007791A1 (de)
ZA (1) ZA967137B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2369997C (en) * 1999-04-28 2009-11-17 Queen's University At Kingston Compositions and methods for treating amyloidosis
RU2196575C2 (ru) * 1999-07-30 2003-01-20 Научно-исследовательский институт фармакологии РАМН Вещество, обладающее психостимулирующим и антиастеническим действием
US6444702B1 (en) 2000-02-22 2002-09-03 Neuromolecular, Inc. Aminoadamantane derivatives as therapeutic agents
RU2226391C2 (ru) * 2002-05-28 2004-04-10 Плотников Владимир Михайлович Средство для повышения активности нейтрофилов
RU2246482C2 (ru) * 2002-12-25 2005-02-20 ООО "Циклан" Способ получения гидрохлорида 1-амино-3,5-диметиладамантана
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) * 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
UA79908C2 (en) * 2004-06-24 2007-07-25 Olainfarm Joint Stock Company Application of polymeric salts 3,5-dimethyl-1-adamantilammonium as immunostimulative and interferonogenous agent
EP1836161B1 (de) 2004-12-22 2016-07-20 BHI Limited Partnership Verfahren und zusammensetzungen zur behandlung von amyloidassoziierten krankheiten
SI2089417T1 (sl) 2006-10-12 2015-04-30 Bhi Limited Partnership Metode, spojine, sestavki in vektorji za dostavo 3-amino-1-propansulfonske kisline
TWI511958B (zh) * 2010-08-09 2015-12-11 Shionogi & Co 胺基金剛烷胺基甲酸酯衍生物之製造方法
CN109922796B (zh) 2016-06-23 2023-04-07 考里安有限责任公司 具有亲水和疏水域的粘合剂基质和治疗剂
EP3490544A1 (de) 2016-07-27 2019-06-05 Corium International, Inc. Transdermale abgabesysteme für memantin
KR102424270B1 (ko) 2016-07-27 2022-07-25 코리움, 인크. 경구 전달과 생물학적으로 동등한 약물동역학을 가진 경피 전달 시스템
JP7071330B2 (ja) 2016-07-27 2022-05-18 コリウム， インコーポレイテッド 炭酸水素ナトリウムのｉｎ ｓｉｔｕ変換で促進されたアミン薬物の経皮送達
WO2019126531A1 (en) 2017-12-20 2019-06-27 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450761A (en) * 1967-03-30 1969-06-17 Sun Oil Co 1-aminoethyldimethyladamantane
DE4014672A1 (de) * 1990-05-08 1991-11-14 Werner E G Prof Dr Mueller Verwendung von adamantan-derivaten zur zytoprotektion von nicht-infizierten und virus-infizierten lymphozyten als auch anderen zelltypen

Also Published As

Publication number Publication date
EP0845984A1 (de) 1998-06-10
NO980793L (no) 1998-02-25
US6255348B1 (en) 2001-07-03
MX9801496A (es) 1998-05-31
JPH11512093A (ja) 1999-10-19
GEP19991779B (en) 1999-10-05
IL123394A (en) 2004-07-25
MX217078B (es) 2003-10-22
CA2230159C (en) 2008-02-26
UA57711C2 (uk) 2003-07-15
DK0845984T3 (da) 2003-06-23
EE04261B1 (et) 2004-04-15
EP0845984B1 (de) 2003-03-12
DE19531342B4 (de) 2007-11-29
EE9800057A (et) 1998-08-17
CN1198669A (zh) 1998-11-11
KR100392986B1 (ko) 2003-11-17
ES2193259T3 (es) 2003-11-01
US6172116B1 (en) 2001-01-09
DE19531342A1 (de) 1997-02-27
CA2230159A1 (en) 1997-03-06
CZ52498A3 (cs) 1999-04-14
AU718219B2 (en) 2000-04-13
CN1282452C (zh) 2006-11-01
DE10399029I1 (de) 2004-01-08
IL123394A0 (en) 1998-09-24
ZA967137B (en) 1997-03-12
RU2219916C2 (ru) 2003-12-27
EP1293201A2 (de) 2003-03-19
KR19990044096A (ko) 1999-06-25
EP1293201A3 (de) 2003-05-21
NO319153B1 (no) 2005-06-27
DE69626650T2 (de) 2003-12-18
DE69626650D1 (de) 2003-04-17
AU6926396A (en) 1997-03-19
CZ299356B6 (cs) 2008-07-02
NO980793D0 (no) 1998-02-25
WO1997007791A1 (en) 1997-03-06

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