EE04261B1 - Aminoadamantaaniühendite kasutamine immunoregulaatoritena - Google Patents

Aminoadamantaaniühendite kasutamine immunoregulaatoritena

Info

Publication number: EE04261B1
Authority: EE; Estonia
Prior art keywords: aminoadamantane; immunoregulators; compounds; aminoadamantane compounds; neutrophils
Prior art date: 1995-08-25

Application number

EE9800057A

Other languages

English (en)

Estonian (et)

Other versions

EE9800057A (et

Inventor

F. Elstner Erich

Original Assignee

Merz + Co. Gmbh & Co.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-25

Filing date

1996-08-21

Publication date

2004-04-15

1996-08-21 Application filed by Merz + Co. Gmbh & Co. filed Critical Merz + Co. Gmbh & Co.

1998-08-17 Publication of EE9800057A publication Critical patent/EE9800057A/xx

2004-04-15 Publication of EE04261B1 publication Critical patent/EE04261B1/xx

Links

DKNWSYNQZKUICI-UHFFFAOYSA-N amantadine Chemical class C1C(C2)CC3CC2CC1(N)C3 DKNWSYNQZKUICI-UHFFFAOYSA-N 0.000 title abstract 2
239000003814 drug Substances 0.000 abstract 2
210000000440 neutrophil Anatomy 0.000 abstract 2
208000030507 AIDS Diseases 0.000 abstract 1
-1 aminoadamantane compound Chemical class 0.000 abstract 1
208000003669 immune deficiency disease Diseases 0.000 abstract 1
210000002381 plasma Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Natural Medicines & Medicinal Plants (AREA)
Mycology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Medical Informatics (AREA)
Botany (AREA)
Biotechnology (AREA)
Alternative & Traditional Medicine (AREA)
Tropical Medicine & Parasitology (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oncology (AREA)
Virology (AREA)
Diabetes (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Investigating Or Analysing Biological Materials (AREA)

EE9800057A 1995-08-25 1996-08-21 Aminoadamantaaniühendite kasutamine immunoregulaatoritena EE04261B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19531342A DE19531342B4 (de)	1995-08-25	1995-08-25	Verwendung von Aminoadamantan-Verbindungen als Immunregulatoren
PCT/EP1996/003678 WO1997007791A1 (en)	1995-08-25	1996-08-21	Use of aminoadamantane compounds as immunoregulators

Publications (2)

Publication Number	Publication Date
EE9800057A EE9800057A (et)	1998-08-17
EE04261B1 true EE04261B1 (et)	2004-04-15

Family

ID=7770407

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9800057A EE04261B1 (et)	1995-08-25	1996-08-21	Aminoadamantaaniühendite kasutamine immunoregulaatoritena

Country Status (21)

Country	Link
US (2)	US6172116B1 (de)
EP (2)	EP0845984B1 (de)
JP (1)	JPH11512093A (de)
KR (1)	KR100392986B1 (de)
CN (1)	CN1282452C (de)
AT (1)	ATE234083T1 (de)
AU (1)	AU718219B2 (de)
CA (1)	CA2230159C (de)
CZ (1)	CZ299356B6 (de)
DE (3)	DE19531342B4 (de)
DK (1)	DK0845984T3 (de)
EE (1)	EE04261B1 (de)
ES (1)	ES2193259T3 (de)
GE (1)	GEP19991779B (de)
IL (1)	IL123394A (de)
MX (1)	MX217078B (de)
NO (1)	NO319153B1 (de)
RU (1)	RU2219916C2 (de)
UA (1)	UA57711C2 (de)
WO (1)	WO1997007791A1 (de)
ZA (1)	ZA967137B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2369997C (en) *	1999-04-28	2009-11-17	Queen's University At Kingston	Compositions and methods for treating amyloidosis
RU2196575C2 (ru) *	1999-07-30	2003-01-20	Научно-исследовательский институт фармакологии РАМН	Вещество, обладающее психостимулирующим и антиастеническим действием
US6444702B1 (en)	2000-02-22	2002-09-03	Neuromolecular, Inc.	Aminoadamantane derivatives as therapeutic agents
RU2226391C2 (ru) *	2002-05-28	2004-04-10	Плотников Владимир Михайлович	Средство для повышения активности нейтрофилов
RU2246482C2 (ru) *	2002-12-25	2005-02-20	ООО "Циклан"	Способ получения гидрохлорида 1-амино-3,5-диметиладамантана
US20070010573A1 (en) *	2003-06-23	2007-01-11	Xianqi Kong	Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) *	2003-06-23	2008-08-19	Neurochem (International) Limited	Methods and compositions for treating amyloid-related diseases
UA79908C2 (en) *	2004-06-24	2007-07-25	Olainfarm Joint Stock Company	Application of polymeric salts 3,5-dimethyl-1-adamantilammonium as immunostimulative and interferonogenous agent
EP1836161B1 (de)	2004-12-22	2016-07-20	BHI Limited Partnership	Verfahren und zusammensetzungen zur behandlung von amyloidassoziierten krankheiten
SI2089417T1 (sl)	2006-10-12	2015-04-30	Bhi Limited Partnership	Metode, spojine, sestavki in vektorji za dostavo 3-amino-1-propansulfonske kisline
TWI511958B (zh) *	2010-08-09	2015-12-11	Shionogi & Co	胺基金剛烷胺基甲酸酯衍生物之製造方法
CN109922796B (zh)	2016-06-23	2023-04-07	考里安有限责任公司	具有亲水和疏水域的粘合剂基质和治疗剂
EP3490544A1 (de)	2016-07-27	2019-06-05	Corium International, Inc.	Transdermale abgabesysteme für memantin
KR102424270B1 (ko)	2016-07-27	2022-07-25	코리움, 인크.	경구 전달과 생물학적으로 동등한 약물동역학을 가진 경피 전달 시스템
JP7071330B2 (ja)	2016-07-27	2022-05-18	コリウム，インコーポレイテッド	炭酸水素ナトリウムのｉｎｓｉｔｕ変換で促進されたアミン薬物の経皮送達
WO2019126531A1 (en)	2017-12-20	2019-06-27	Corium, Inc.	Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3450761A (en) *	1967-03-30	1969-06-17	Sun Oil Co	1-aminoethyldimethyladamantane
DE4014672A1 (de) *	1990-05-08	1991-11-14	Werner E G Prof Dr Mueller	Verwendung von adamantan-derivaten zur zytoprotektion von nicht-infizierten und virus-infizierten lymphozyten als auch anderen zelltypen

1995
- 1995-08-25 DE DE19531342A patent/DE19531342B4/de not_active Expired - Fee Related
1996
- 1996-08-21 MX MX9801496A patent/MX217078B/es not_active IP Right Cessation
- 1996-08-21 DE DE69626650T patent/DE69626650T2/de not_active Expired - Fee Related
- 1996-08-21 DE DE2003199029 patent/DE10399029I1/de active Pending
- 1996-08-21 EE EE9800057A patent/EE04261B1/xx not_active IP Right Cessation
- 1996-08-21 CN CNB961973471A patent/CN1282452C/zh not_active Expired - Fee Related
- 1996-08-21 KR KR19980701329A patent/KR100392986B1/ko not_active Expired - Fee Related
- 1996-08-21 UA UA98031521A patent/UA57711C2/uk unknown
- 1996-08-21 EP EP96930065A patent/EP0845984B1/de not_active Expired - Lifetime
- 1996-08-21 US US09/029,335 patent/US6172116B1/en not_active Expired - Fee Related
- 1996-08-21 RU RU98105150/14A patent/RU2219916C2/ru not_active IP Right Cessation
- 1996-08-21 WO PCT/EP1996/003678 patent/WO1997007791A1/en not_active Ceased
- 1996-08-21 EP EP02026914A patent/EP1293201A3/de not_active Withdrawn
- 1996-08-21 GE GEAP19964199A patent/GEP19991779B/en unknown
- 1996-08-21 ES ES96930065T patent/ES2193259T3/es not_active Expired - Lifetime
- 1996-08-21 CA CA002230159A patent/CA2230159C/en not_active Expired - Fee Related
- 1996-08-21 AT AT96930065T patent/ATE234083T1/de not_active IP Right Cessation
- 1996-08-21 IL IL12339496A patent/IL123394A/en not_active IP Right Cessation
- 1996-08-21 CZ CZ0052498A patent/CZ299356B6/cs not_active IP Right Cessation
- 1996-08-21 AU AU69263/96A patent/AU718219B2/en not_active Ceased
- 1996-08-21 DK DK96930065T patent/DK0845984T3/da active
- 1996-08-21 JP JP9509816A patent/JPH11512093A/ja active Pending
- 1996-08-22 ZA ZA967137A patent/ZA967137B/xx unknown
1998
- 1998-02-25 NO NO19980793A patent/NO319153B1/no unknown
2000
- 2000-09-22 US US09/667,805 patent/US6255348B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0845984A1 (de)	1998-06-10
NO980793L (no)	1998-02-25
US6255348B1 (en)	2001-07-03
MX9801496A (es)	1998-05-31
JPH11512093A (ja)	1999-10-19
GEP19991779B (en)	1999-10-05
IL123394A (en)	2004-07-25
MX217078B (es)	2003-10-22
CA2230159C (en)	2008-02-26
UA57711C2 (uk)	2003-07-15
DK0845984T3 (da)	2003-06-23
EP0845984B1 (de)	2003-03-12
DE19531342B4 (de)	2007-11-29
EE9800057A (et)	1998-08-17
CN1198669A (zh)	1998-11-11
KR100392986B1 (ko)	2003-11-17
ES2193259T3 (es)	2003-11-01
US6172116B1 (en)	2001-01-09
DE19531342A1 (de)	1997-02-27
CA2230159A1 (en)	1997-03-06
CZ52498A3 (cs)	1999-04-14
AU718219B2 (en)	2000-04-13
CN1282452C (zh)	2006-11-01
DE10399029I1 (de)	2004-01-08
IL123394A0 (en)	1998-09-24
ZA967137B (en)	1997-03-12
RU2219916C2 (ru)	2003-12-27
EP1293201A2 (de)	2003-03-19
KR19990044096A (ko)	1999-06-25
EP1293201A3 (de)	2003-05-21
NO319153B1 (no)	2005-06-27
DE69626650T2 (de)	2003-12-18
DE69626650D1 (de)	2003-04-17
AU6926396A (en)	1997-03-19
CZ299356B6 (cs)	2008-07-02
NO980793D0 (no)	1998-02-25
ATE234083T1 (de)	2003-03-15
WO1997007791A1 (en)	1997-03-06

Legal Events

Date	Code	Title	Description
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2009-04-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20080821

Publication	Publication Date	Title
EE9800057A (et)	1998-08-17	Aminoadamantaaniühendite kasutamine immunoregulaatoritena
RU94038043A (ru)	1996-11-20	Применение замещенных производных аденина для лечения множественного склероза
AU1373499A (en)	1999-06-07	Use of 9-deoxy-2', 9-alpha-methano-3- oxa-4,5,6- trinor-3, 7-(1',3'-interphenylene) -13,14-dihydro- prostaglandin f1 to treat peripheral vascular disease
FI945625A0 (fi)	1994-11-29	Indolokarbatsoli-imidit ja niiden käyttö
HU913283D0 (en)	1992-01-28	Process for the production of hydroximethyl-(methylene-cyclopentyl)-purines and pirimidines, their medically usable salts, and of medical preparations containing them
HU910681D0 (en)	1991-09-30	Medical solution
DE60234577D1 (de)	2010-01-14	Pharmazeutische mischung zur behandlung von krebs, die dioxolan nukleosidanalogen enthält
ATE181329T1 (de)	1999-07-15	Substituierte dibenzooxazepin-verbindungen, pharmazeutische zusammensetzungen und verfahren zur verwendung
CA2218561A1 (en)	1996-07-11	Compounds and methods of use to treat infectious diseases
EP0342587A3 (de)	1991-05-22	Thienotriazolodiazepine und ihre pharmazeutische Verwendung
IT1245717B (it)	1994-10-14	Composto farmaceutico a base di un antocianidina per il trattamento di malattie oftalmiche
EP0577446A3 (de)	1995-04-05	Verfahren zur Herstellung von optisch-aktiven Halogen-enthaltenden Alkoholen.
NZ335057A (en)	2000-09-29	Pentaerythritol derivatives, their production and use and intermediates for their synthesis
DE68901172D1 (de)	1992-05-14	(-)-2-pyrazolinverbindung, deren optischen aufspaltung und therapeutisches agens zur behandlung von zerebralen gefaesskrankheiten, diese verbindung als aktives ingredient enthaltend.
ATE145911T1 (de)	1996-12-15	Inositol-phosphat-analog als kalzium- antagonistische substanz
IT1223395B (it)	1990-09-19	Composti ad attivita' cardiovascolare
OA09197A (fr)	1992-06-30	"Peptides SDK, leur procédé de préparation ainsi que des compositions thérapeutiques en contenant".
EP0566485A3 (de)	1995-03-15	Verfahren zur Herstellung eines optisch aktiven Halogen enthaltenden Alkohols.
EP0721985A4 (de)	1998-08-26	Die substanz it-62-b und sie enthaltende medizinische zubereitungen
RU94034011A (ru)	1997-04-20	Способ лечения психического расстройства
ES2037825T3 (es)	1993-07-01	Uso farmaceutico de tioeteres aromaticos.
DK653687A (da)	1988-06-13	Middel til behandling af nyresygdomme
TH50173A (th)	2002-03-18	การใช้ 1-ไฮดรอกซี-2-ไพริโดนสำหรับการบำบัดการติดเชื้อที่ผิวหนัง
ID21321A (id)	1999-05-27	Senyawa-senyawa betha-laktam untuk pengobatan penyakit infeksi disebabkan mikroorganisme penghasil betha-laktamase
UA31266A (uk)	2000-12-15	Лікувальний засіб "дінальгін"