ATE234111T1 - Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung - Google Patents
Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutungInfo
- Publication number
- ATE234111T1 ATE234111T1 AT97929697T AT97929697T ATE234111T1 AT E234111 T1 ATE234111 T1 AT E234111T1 AT 97929697 T AT97929697 T AT 97929697T AT 97929697 T AT97929697 T AT 97929697T AT E234111 T1 ATE234111 T1 AT E234111T1
- Authority
- AT
- Austria
- Prior art keywords
- trauma
- protein products
- people
- bpi protein
- therapeutic uses
- Prior art date
Links
- 208000014674 injury Diseases 0.000 title abstract 2
- 230000008733 trauma Effects 0.000 title abstract 2
- 230000000740 bleeding effect Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 208000032843 Hemorrhage Diseases 0.000 abstract 1
- 102000052586 bactericidal permeability increasing protein Human genes 0.000 abstract 1
- 108010032816 bactericidal permeability increasing protein Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1751—Bactericidal/permeability-increasing protein [BPI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Marine Sciences & Fisheries (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65229296A | 1996-05-23 | 1996-05-23 | |
| PCT/US1997/008941 WO1997044056A1 (en) | 1996-05-23 | 1997-05-23 | Therapeutic uses of bpi protein products in humans with hemorrhage due to trauma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234111T1 true ATE234111T1 (de) | 2003-03-15 |
Family
ID=24616300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97929697T ATE234111T1 (de) | 1996-05-23 | 1997-05-23 | Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5945399A (de) |
| EP (1) | EP0907372B1 (de) |
| JP (1) | JP2000511190A (de) |
| CN (1) | CN1155403C (de) |
| AT (1) | ATE234111T1 (de) |
| AU (1) | AU736096B2 (de) |
| CA (1) | CA2255539C (de) |
| DE (1) | DE69719754D1 (de) |
| NZ (1) | NZ332954A (de) |
| WO (1) | WO1997044056A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
| US6214789B1 (en) * | 1993-03-12 | 2001-04-10 | Xoma Corporation | Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products |
| US5652332A (en) * | 1993-03-12 | 1997-07-29 | Xoma | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| WO1997004008A1 (en) * | 1995-07-20 | 1997-02-06 | Xoma Corporation | Anti-fungal peptides |
| US5888973A (en) | 1996-08-09 | 1999-03-30 | Xoma Corporation | Anti-chlamydial uses of BPI protein products |
| US6482796B2 (en) | 1996-11-01 | 2002-11-19 | Xoma Corporation | Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients |
| US6093573A (en) * | 1997-06-20 | 2000-07-25 | Xoma | Three-dimensional structure of bactericidal/permeability-increasing protein (BPI) |
| US6528255B1 (en) * | 1997-12-30 | 2003-03-04 | Genencor International, Inc. | Proteases from gram positive organisms |
| US6013631A (en) * | 1998-06-19 | 2000-01-11 | Xoma Corporation | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
| CN1324244A (zh) | 1998-10-22 | 2001-11-28 | 伊莱利利公司 | 治疗脓毒症的方法 |
| CN1335757A (zh) * | 1998-11-12 | 2002-02-13 | 聚合体生物科学公司 | 可用于快速凝血和止血的止血聚合物 |
| US6162237A (en) * | 1999-04-19 | 2000-12-19 | Chan; Winston Kam Yew | Temporary intravascular stent for use in retrohepatic IVC or hepatic vein injury |
| US20020173464A1 (en) * | 2000-12-01 | 2002-11-21 | King George L. | Modulation of pericyte proliferation |
| EP1469865A4 (de) * | 2001-12-31 | 2010-04-14 | Crosslink D Inc | Hämostatische zusammensetzungen und verfahren zur kontrolle von blutungen |
| EP1741440A1 (de) | 2005-07-08 | 2007-01-10 | Mellitus S.L. | Verwendung von BPI-proteine zur Behandlung von stoffwechselbedingten Erkrankungen und Herzkreislaufstörungen |
| CA2623531C (en) * | 2005-10-07 | 2013-12-10 | Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa | Matrix metalloproteinase 11 vaccine |
| CN2887006Y (zh) * | 2005-11-30 | 2007-04-04 | 富士康(昆山)电脑接插件有限公司 | 电子装置的屏蔽构造 |
| US20070248653A1 (en) * | 2006-04-20 | 2007-10-25 | Cochrum Kent C | Hemostatic compositions and methods for controlling bleeding |
| GB201319621D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Antimicrobial agents and their use in therapy |
| GB201319620D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Immunosuppressive agents and their use in therapy |
| CN106020478B (zh) * | 2016-05-20 | 2019-09-13 | 青岛海信电器股份有限公司 | 一种智能终端操控方法、装置和智能终端 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5245013A (en) * | 1985-04-30 | 1993-09-14 | Richard Ulevitch | Acute phase protein modulating endotoxic activity of lipopolysaccharides, assay methods and polypeptides |
| EP0652230B1 (de) * | 1987-08-11 | 2005-12-14 | New York University | Biologisch-aktive Bakterizide/permeabilitätserhöhende Proteinbruchstücke |
| US5576292A (en) * | 1987-08-11 | 1996-11-19 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
| US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
| US5234912A (en) * | 1989-02-14 | 1993-08-10 | Incyte Pharmaceuticals, Inc. | Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof |
| US5308834A (en) * | 1989-02-14 | 1994-05-03 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and prevention thereof using a BPI protein |
| US5089274A (en) * | 1989-02-14 | 1992-02-18 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders |
| US5334584A (en) * | 1989-02-14 | 1994-08-02 | Incyte Pharamaceuticals, Inc. | Recombinant, non-glycosylated bpi protein and uses thereof |
| US5171739A (en) * | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
| DK0485430T3 (da) * | 1989-08-01 | 1999-06-14 | Scripps Research Inst | Fremgangsmåder og sammensætninger til bedring af symptomer på sepsis |
| EP0563222B1 (de) * | 1990-12-03 | 1998-02-25 | New York University | Biologisch aktive bakterizide/permeabilitätserhöhende proteinbruchstücke |
| WO1993006228A1 (en) * | 1991-09-26 | 1993-04-01 | Incyte Pharmaceuticals, Inc. | A new form of liposaccharide binding protein (lbp) |
| AU669723B2 (en) * | 1992-05-19 | 1996-06-20 | Xoma Corporation | Improved methods for the preparation of endotoxin-binding proteins |
| US5643570A (en) * | 1992-05-19 | 1997-07-01 | Xoma Corporation | BPI-immunoglobulin fusion proteins |
| JP3946246B2 (ja) * | 1993-02-02 | 2007-07-18 | ゾーマ・コーポレイション | 殺菌性/浸透性増大タンパク質(Bactericidal/Permeability Increasing protein:BPI)及び界面活性剤を含有する医薬組成物 |
| US5420019A (en) * | 1993-02-02 | 1995-05-30 | Xoma Corporation | Stable bactericidal/permeability-increasing protein muteins |
| ES2123134T3 (es) * | 1993-03-12 | 1999-01-01 | Xoma Corp | Peptidos biologicamente activos de dominios funcionales de la proteina bactericida aumentadora de la permeabilidad y usos de los mismos. |
| CA2157925C (en) * | 1993-03-12 | 2000-06-06 | Xoma Corporation | Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products |
| US5348942A (en) * | 1993-03-12 | 1994-09-20 | Xoma Corporation | Therapeutic uses of bactericidal/permeability increasing protein products |
| JPH08509703A (ja) * | 1993-03-12 | 1996-10-15 | ゾーマ コーポレイション | 殺菌/透過性増加タンパク質産物の治療用途 |
| US5733872A (en) * | 1993-03-12 | 1998-03-31 | Xoma Corporation | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| AU6522794A (en) * | 1993-03-22 | 1994-10-11 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein and lipopolysaccharide binding protein levels and ratios thereof in diagnosis |
| EP0760849A1 (de) * | 1993-04-30 | 1997-03-12 | Incyte Pharmaceuticals, Inc. | Rekombinante, aud bpi und lbp basierende proteine, die für sie kodierenden nukleinsäuren, verfahren zu ihrer herstellung und ihre verwendung |
| WO1995000641A1 (en) * | 1993-06-17 | 1995-01-05 | Xoma Corporation | Lipopolysaccharide binding protein derivatives |
| WO1995001428A1 (en) * | 1993-07-02 | 1995-01-12 | Incyte Pharmaceuticals, Inc. | Glycosylated and non-glycosylated bactericidal/permeability increasing proteins, and methods for producing same |
| WO1995002414A1 (en) * | 1993-07-14 | 1995-01-26 | Xoma Corporation | Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products |
| US5466580A (en) * | 1993-09-22 | 1995-11-14 | Xoma Corporation | Method for quantifying BPI in body fluids |
| CN1133634A (zh) * | 1993-09-22 | 1996-10-16 | 爱克斯欧玛公司 | 定量体液中的bpi的方法 |
| PT759774E (pt) * | 1993-09-22 | 2002-11-29 | Xoma Technology Ltd | Metodo para o tratamento de infeccoes bacterianas gram-negativas por administracao de um produto de proteina bactericida indutora da permeabilidade (bip) e de um antibiotico |
| CA2173611C (en) * | 1993-10-05 | 2005-07-26 | Paul A. M. Van Leeuwen | Method of treating depressed reticuloendothelial system function |
| ATE219684T1 (de) * | 1994-01-14 | 2002-07-15 | Xoma Technology Ltd | Anti gram positive bakterielle verfahren und mittel |
| MX9602570A (es) * | 1994-01-14 | 1997-04-30 | Xoma Corp | Metodos y materiales anti-fungosos. |
| US5484705A (en) * | 1994-01-24 | 1996-01-16 | Xoma Corporation | Method for quantifying lipopolysaccharide binding protein |
| US5643875A (en) * | 1994-01-24 | 1997-07-01 | Friedmann; Nadav | Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products |
| US5447913A (en) * | 1994-03-11 | 1995-09-05 | Xoma Corporation | Therapeutic uses of bactericidal/permeability-increasing protein dimer products |
| US5578568A (en) * | 1994-04-22 | 1996-11-26 | Xoma Corporation | Method of treating conditions associated with intestinal ischemia/reperfusion |
| US5532216A (en) * | 1994-06-24 | 1996-07-02 | Incyte Pharmaceuticals, Inc. | Neutralization of non-lipopolysaccharide compounds by bactericidal/permeability-increasing protein |
| US5646114A (en) * | 1994-07-11 | 1997-07-08 | Xoma Corporation | Anti-protozoan methods |
| ATE256147T1 (de) * | 1994-09-15 | 2003-12-15 | Xoma Technology Ltd | Peptide gegen pilzen |
| US5912228A (en) * | 1995-01-13 | 1999-06-15 | Xoma Corporation | Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products |
| US5494896A (en) * | 1995-03-31 | 1996-02-27 | Xoma Corporation | Method of treating conditions associated with burn injuries |
-
1997
- 1997-05-23 NZ NZ332954A patent/NZ332954A/xx unknown
- 1997-05-23 WO PCT/US1997/008941 patent/WO1997044056A1/en not_active Ceased
- 1997-05-23 CA CA002255539A patent/CA2255539C/en not_active Expired - Fee Related
- 1997-05-23 CN CNB971957282A patent/CN1155403C/zh not_active Expired - Fee Related
- 1997-05-23 AU AU33693/97A patent/AU736096B2/en not_active Ceased
- 1997-05-23 DE DE69719754T patent/DE69719754D1/de not_active Expired - Lifetime
- 1997-05-23 EP EP97929697A patent/EP0907372B1/de not_active Expired - Lifetime
- 1997-05-23 JP JP09542841A patent/JP2000511190A/ja active Pending
- 1997-05-23 AT AT97929697T patent/ATE234111T1/de not_active IP Right Cessation
- 1997-05-23 US US08/862,785 patent/US5945399A/en not_active Expired - Fee Related
- 1997-09-10 US US08/927,438 patent/US5756464A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU736096B2 (en) | 2001-07-26 |
| AU3369397A (en) | 1997-12-09 |
| NZ332954A (en) | 2000-07-28 |
| EP0907372B1 (de) | 2003-03-12 |
| CA2255539C (en) | 2005-09-27 |
| CN1155403C (zh) | 2004-06-30 |
| US5756464A (en) | 1998-05-26 |
| CA2255539A1 (en) | 1997-11-27 |
| WO1997044056A1 (en) | 1997-11-27 |
| US5945399A (en) | 1999-08-31 |
| DE69719754D1 (de) | 2003-04-17 |
| JP2000511190A (ja) | 2000-08-29 |
| CN1222859A (zh) | 1999-07-14 |
| EP0907372A1 (de) | 1999-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |