ATE234828T1 - Hydronaphtho(2,3-c)furan-derivate und verfahren zu ihrer herstellung - Google Patents

Hydronaphtho(2,3-c)furan-derivate und verfahren zu ihrer herstellung

Info

Publication number: ATE234828T1
Authority: AT; Austria
Prior art keywords: group; denotes; substituted; denote; hydrogen atom
Prior art date: 1998-12-11

Application number

AT99959746T

Other languages

English (en)

Inventor

Shiro Terashima

Masanori Takadoi

Akihiro Ishiwata

Tadashi Katoh

Original Assignee

Sagami Chem Res

Kyorin Seiyaku Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-11

Filing date

1999-12-10

Publication date

2003-04-15

1999-12-10 Application filed by Sagami Chem Res, Kyorin Seiyaku Kk filed Critical Sagami Chem Res

2003-04-15 Application granted granted Critical

2003-04-15 Publication of ATE234828T1 publication Critical patent/ATE234828T1/de

Links

YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical class C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000004423 acyloxy group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
125000002102 aryl alkyloxo group Chemical group 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
239000000543 intermediate Substances 0.000 abstract 2
125000004430 oxygen atom Chemical group O* 0.000 abstract 2
102000017926 CHRM2 Human genes 0.000 abstract 1
101150012960 Chrm2 gene Proteins 0.000 abstract 1
FMPNFDSPHNUFOS-HQEQRHKESA-N Himbacine Natural products C(/[C@@H]1[C@H]2CCCC[C@@H]2C[C@@H]2C(=O)O[C@H]([C@H]12)C)=C\[C@@H]1CCC[C@H](C)N1C FMPNFDSPHNUFOS-HQEQRHKESA-N 0.000 abstract 1
UQOFGTXDASPNLL-XHNCKOQMSA-N Muscarine Chemical compound C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O UQOFGTXDASPNLL-XHNCKOQMSA-N 0.000 abstract 1
FMPNFDSPHNUFOS-UHFFFAOYSA-N N-Methyl-himandravin Natural products C12C(C)OC(=O)C2CC2CCCCC2C1C=CC1CCCC(C)N1C FMPNFDSPHNUFOS-UHFFFAOYSA-N 0.000 abstract 1
229930013930 alkaloid Natural products 0.000 abstract 1
150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
230000008485 antagonism Effects 0.000 abstract 1
FMPNFDSPHNUFOS-LPJDIUFZSA-N himbacine Chemical compound C(/[C@@H]1[C@H]2CCCC[C@@H]2C[C@@H]2C(=O)O[C@H]([C@H]12)C)=C\[C@H]1CCC[C@H](C)N1C FMPNFDSPHNUFOS-LPJDIUFZSA-N 0.000 abstract 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Furan Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT99959746T 1998-12-11 1999-12-10 Hydronaphtho(2,3-c)furan-derivate und verfahren zu ihrer herstellung ATE234828T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP35299198		1998-12-11
JP11348326A JP2000229961A (ja)	1998-12-11	1999-12-08	ヒドロナフト［２，３−ｃ］フラン誘導体およびその製造方法
PCT/JP1999/006937 WO2000035898A1 (en)	1998-12-11	1999-12-10	HYDRONAPHTHO[2,3-c]FURAN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF

Publications (1)

Publication Number	Publication Date
ATE234828T1 true ATE234828T1 (de)	2003-04-15

Family

ID=26578721

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99959746T ATE234828T1 (de)	1998-12-11	1999-12-10	Hydronaphtho(2,3-c)furan-derivate und verfahren zu ihrer herstellung

Country Status (9)

Country	Link
US (1)	US6392059B1 (de)
EP (1)	EP1138679B1 (de)
JP (1)	JP2000229961A (de)
AT (1)	ATE234828T1 (de)
AU (1)	AU1683500A (de)
CA (1)	CA2354516A1 (de)
DE (1)	DE69906131T2 (de)
DK (1)	DK1138679T3 (de)
WO (1)	WO2000035898A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7488742B2 (en) *	2000-06-15	2009-02-10	Schering Corporation	Thrombin receptor antagonists
ES2291323T3 (es) *	2000-06-15	2008-03-01	Schering Corporation	Antagonistas de receptores de trombina.
BR0213967A (pt)	2001-10-18	2005-08-30	Schering Corp	Análogos de himbacina como antagonistas do receptor de trombina
US20050124658A1 (en) *	2001-12-25	2005-06-09	Segami Chemical Research Center	Decahydronaphtho[2,3-c]furan derivatives
EP3219746A1 (de) *	2016-03-15	2017-09-20	Sika Technology AG	Polymermischungen enthaltend mindestens zwei unterschiedliche kammpolymere

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5716952A (en) *	1992-03-18	1998-02-10	Allergan	Method for reducing intraocular pressure in the mammalian eye by administration of muscarinic antagonists
KR100393492B1 (ko)	1997-11-25	2003-08-02	쉐링 코포레이션	트롬빈 수용체 길항제
US6063847A (en) *	1997-11-25	2000-05-16	Schering Corporation	Thrombin receptor antagonists

1999
- 1999-12-08 JP JP11348326A patent/JP2000229961A/ja active Pending
- 1999-12-10 DK DK99959746T patent/DK1138679T3/da active
- 1999-12-10 DE DE69906131T patent/DE69906131T2/de not_active Expired - Fee Related
- 1999-12-10 AT AT99959746T patent/ATE234828T1/de not_active IP Right Cessation
- 1999-12-10 EP EP99959746A patent/EP1138679B1/de not_active Expired - Lifetime
- 1999-12-10 WO PCT/JP1999/006937 patent/WO2000035898A1/ja not_active Ceased
- 1999-12-10 AU AU16835/00A patent/AU1683500A/en not_active Abandoned
- 1999-12-10 CA CA002354516A patent/CA2354516A1/en not_active Abandoned
- 1999-12-10 US US09/856,462 patent/US6392059B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2000229961A (ja)	2000-08-22
DE69906131T2 (de)	2004-01-29
DK1138679T3 (da)	2003-04-22
WO2000035898A1 (en)	2000-06-22
EP1138679A4 (de)	2002-01-16
EP1138679B1 (de)	2003-03-19
AU1683500A (en)	2000-07-03
EP1138679A1 (de)	2001-10-04
DE69906131D1 (de)	2003-04-24
US6392059B1 (en)	2002-05-21
CA2354516A1 (en)	2000-06-22

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Legal Events

Date	Code	Title	Description
2003-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties