ATE234835T1 - Trovafloxacin enhaltende suspensionen zur oralen anwendung - Google Patents
Trovafloxacin enhaltende suspensionen zur oralen anwendungInfo
- Publication number
- ATE234835T1 ATE234835T1 AT00304550T AT00304550T ATE234835T1 AT E234835 T1 ATE234835 T1 AT E234835T1 AT 00304550 T AT00304550 T AT 00304550T AT 00304550 T AT00304550 T AT 00304550T AT E234835 T1 ATE234835 T1 AT E234835T1
- Authority
- AT
- Austria
- Prior art keywords
- trovafloxacin
- crystals
- oral use
- suspensions containing
- novel
- Prior art date
Links
- 239000000725 suspension Substances 0.000 title abstract 3
- WVPSKSLAZQPAKQ-CDMJZVDBSA-N trovafloxacin Chemical compound C([C@H]1[C@@H]([C@H]1C1)N)N1C(C(=CC=1C(=O)C(C(O)=O)=C2)F)=NC=1N2C1=CC=C(F)C=C1F WVPSKSLAZQPAKQ-CDMJZVDBSA-N 0.000 title abstract 2
- 229960000497 trovafloxacin Drugs 0.000 title abstract 2
- 239000013078 crystal Substances 0.000 abstract 4
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13746399P | 1999-06-04 | 1999-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234835T1 true ATE234835T1 (de) | 2003-04-15 |
Family
ID=22477550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00304550T ATE234835T1 (de) | 1999-06-04 | 2000-05-30 | Trovafloxacin enhaltende suspensionen zur oralen anwendung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6239141B1 (de) |
| EP (1) | EP1057828B1 (de) |
| JP (1) | JP3465820B2 (de) |
| AT (1) | ATE234835T1 (de) |
| BR (1) | BR0002577A (de) |
| CA (1) | CA2311112A1 (de) |
| DE (1) | DE60001687T2 (de) |
| DK (1) | DK1057828T3 (de) |
| ES (1) | ES2194677T3 (de) |
| PT (1) | PT1057828E (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU230030B1 (hu) | 1999-10-08 | 2015-05-28 | Debiopharm International Sa | Fab I inhibitorok |
| WO2002072102A1 (en) * | 2001-03-05 | 2002-09-19 | Ortho-Mcneil Pharmaceutical, Inc. | Taste masked liquid pharmaceutical compositions |
| EP1560584B1 (de) * | 2001-04-06 | 2009-01-14 | Affinium Pharmaceuticals, Inc. | Fab-i-inhibitoren |
| US20030068829A1 (en) * | 2001-06-25 | 2003-04-10 | Symyx Technologies, Inc. | High throughput crystallographic screening of materials |
| CA2453182A1 (en) * | 2001-07-10 | 2003-01-23 | Meredith L. Greene | Crystalline thiazine oxazolidinones |
| CN100364991C (zh) * | 2001-08-15 | 2008-01-30 | 法玛西雅厄普约翰美国公司 | 2,4-二甲基-1h-吡咯-3-甲酰胺衍生物的苹果酸盐的晶体、其制备方法和其组合物 |
| WO2003077842A2 (en) * | 2002-03-12 | 2003-09-25 | Bristol-Myers Squibb Company | Palatable oral suspension and method |
| WO2003093322A2 (en) * | 2002-04-30 | 2003-11-13 | The Population Council, Inc. | Carrageenan based antimicrobial compositions |
| US8367098B2 (en) * | 2002-04-30 | 2013-02-05 | The Population Council, Inc. | Unique combinations of antimicrobial compositions |
| EP1575951B1 (de) * | 2002-12-06 | 2014-06-25 | Debiopharm International SA | Heterozyclische verbindungen, verfahren zu deren herstellung und ihre verwendung als heilmittel |
| WO2004082586A2 (en) | 2003-03-17 | 2004-09-30 | Affinium Pharmaceuticals, Inc. | Phamaceutical compositions comprising inhibitors of fab i and further antibiotics |
| MXPA06000524A (es) * | 2003-07-18 | 2006-08-11 | Santarus Inc | Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido. |
| DK1828167T3 (da) * | 2004-06-04 | 2014-10-20 | Debiopharm Int Sa | Acrylamidderivater som antibiotiske midler |
| KR20080075027A (ko) * | 2005-12-05 | 2008-08-13 | 아피늄 파마슈티컬스, 인크. | Ｆａｂｉ 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물 |
| JP5468899B2 (ja) | 2006-07-20 | 2014-04-09 | アフィニウム ファーマシューティカルズ， インク． | Ｆａｂｉインヒビターとしてのアクリルアミド誘導体 |
| EP2125802A4 (de) | 2007-02-16 | 2014-08-20 | Debiopharm Int Sa | Salze, prodrugs und polymorphe von fab-i-inhibitoren |
| AU2013279021C1 (en) | 2012-06-19 | 2017-03-16 | Debiopharm International Sa | Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide |
| RS61312B1 (sr) | 2016-02-26 | 2021-02-26 | Debiopharm Int Sa | Lek za lečenje infekcija dijabetskog stopala |
| TN2021000159A1 (en) | 2019-02-14 | 2023-04-04 | Debiopharm Int Sa | Afabicin formulation, method for making the same and uses thereof |
| SG11202113174SA (en) | 2019-06-14 | 2021-12-30 | Debiopharm Int Sa | Medicament and use thereof for treating bacterial infections involving biofilm |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5164402A (en) | 1989-08-16 | 1992-11-17 | Pfizer Inc | Azabicyclo quinolone and naphthyridinone carboxylic acids |
| US5266559A (en) | 1989-10-27 | 1993-11-30 | Firmenich S.A. | Use of unsaturated macrocyclic lactones as perfuming ingredients |
| US5391763A (en) | 1990-07-11 | 1995-02-21 | Pfizer Inc. | 3-aza-bicyclo[3.1.0]hexanes which are intermediates for anti-bacterial azabicyclo quinolone carboxylic acids |
| TW271400B (de) | 1992-07-30 | 1996-03-01 | Pfizer | |
| DK0789697T3 (da) | 1995-06-06 | 1998-10-19 | Pfizer | Krystalform af vandfrit 7-([1alfa, 5alfa, 6alfa,]-6-amino-3-azabicyclo[3.1.0]hex-3-yl)-6-fluor-1-(2,4-difluorphenyl)-1,4-d |
| US6080756A (en) * | 1995-08-29 | 2000-06-27 | Pfizer Inc. | Polymorphs of the prodrug 6-N-(L-ALA-L-ALA)-trovafloxacin |
| WO1997007800A1 (en) * | 1995-08-29 | 1997-03-06 | Pfizer Inc. | Zwitterionic forms of trovafloxacin |
| US6114531A (en) * | 1998-07-28 | 2000-09-05 | Pfizer Inc. | Process for preparing quinolone and naphthyridone carboxylic acids |
-
2000
- 2000-05-05 US US09/565,420 patent/US6239141B1/en not_active Expired - Fee Related
- 2000-05-16 JP JP2000142971A patent/JP3465820B2/ja not_active Expired - Fee Related
- 2000-05-30 DK DK00304550T patent/DK1057828T3/da active
- 2000-05-30 PT PT00304550T patent/PT1057828E/pt unknown
- 2000-05-30 DE DE60001687T patent/DE60001687T2/de not_active Expired - Fee Related
- 2000-05-30 AT AT00304550T patent/ATE234835T1/de not_active IP Right Cessation
- 2000-05-30 ES ES00304550T patent/ES2194677T3/es not_active Expired - Lifetime
- 2000-05-30 EP EP00304550A patent/EP1057828B1/de not_active Expired - Lifetime
- 2000-06-02 CA CA002311112A patent/CA2311112A1/en not_active Abandoned
- 2000-06-05 BR BR0002577-1A patent/BR0002577A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP3465820B2 (ja) | 2003-11-10 |
| EP1057828B1 (de) | 2003-03-19 |
| DE60001687T2 (de) | 2003-12-18 |
| JP2000344770A (ja) | 2000-12-12 |
| CA2311112A1 (en) | 2000-12-04 |
| EP1057828A2 (de) | 2000-12-06 |
| ES2194677T3 (es) | 2003-12-01 |
| DE60001687D1 (de) | 2003-04-24 |
| US6239141B1 (en) | 2001-05-29 |
| PT1057828E (pt) | 2003-07-31 |
| DK1057828T3 (da) | 2003-07-14 |
| EP1057828A3 (de) | 2001-05-16 |
| BR0002577A (pt) | 2001-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1057828 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |