ES2194677T3 - Suspensiones de trovafloxacina de administracion por via oral. - Google Patents

Suspensiones de trovafloxacina de administracion por via oral.

Info

Publication number
ES2194677T3
ES2194677T3 ES00304550T ES00304550T ES2194677T3 ES 2194677 T3 ES2194677 T3 ES 2194677T3 ES 00304550 T ES00304550 T ES 00304550T ES 00304550 T ES00304550 T ES 00304550T ES 2194677 T3 ES2194677 T3 ES 2194677T3
Authority
ES
Spain
Prior art keywords
suspensions
crystals
trovafloxacine
administration via
via oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00304550T
Other languages
English (en)
Inventor
Douglas John Allen
Sojka Sonja Sekulic
Daniel Ray Arenson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Application granted granted Critical
Publication of ES2194677T3 publication Critical patent/ES2194677T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)

Abstract

Un cristal de ión bipolar de trovafloxacina de la **fórmula** con una forma de tablillas de seis caras, que presenta el siguiente patrón de difracción de rayos X de torta húmeda. Nº de 1 2 3 4 5 6 7 8 9 pico 2q(°) 6, 2 8, 6 11, 12, 12, 8 16, 16, 8 18, 19, 5 Cu 8 4 1 6 espacio 14, 3 10, 7, 5 7, 1 6, 9 5, 5 5, 3 4, 8 4, 5 d 0 Nº de 10 11 12 13 14 15 16 17 18 pico 2q(°) 20, 1 22, 23, 26, 28, 3 29, 37, 7 39, Cu 6 7 7 9 0 espacio 4, 4 4, 1 3, 8 3, 3 3, 2 3, 0 2, 4 2, 3 d
ES00304550T 1999-06-04 2000-05-30 Suspensiones de trovafloxacina de administracion por via oral. Expired - Lifetime ES2194677T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13746399P 1999-06-04 1999-06-04

Publications (1)

Publication Number Publication Date
ES2194677T3 true ES2194677T3 (es) 2003-12-01

Family

ID=22477550

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00304550T Expired - Lifetime ES2194677T3 (es) 1999-06-04 2000-05-30 Suspensiones de trovafloxacina de administracion por via oral.

Country Status (10)

Country Link
US (1) US6239141B1 (es)
EP (1) EP1057828B1 (es)
JP (1) JP3465820B2 (es)
AT (1) ATE234835T1 (es)
BR (1) BR0002577A (es)
CA (1) CA2311112A1 (es)
DE (1) DE60001687T2 (es)
DK (1) DK1057828T3 (es)
ES (1) ES2194677T3 (es)
PT (1) PT1057828E (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230030B1 (hu) 1999-10-08 2015-05-28 Debiopharm International Sa Fab I inhibitorok
WO2002072102A1 (en) * 2001-03-05 2002-09-19 Ortho-Mcneil Pharmaceutical, Inc. Taste masked liquid pharmaceutical compositions
EP1560584B1 (en) * 2001-04-06 2009-01-14 Affinium Pharmaceuticals, Inc. Fab i inhibitors
US20030068829A1 (en) * 2001-06-25 2003-04-10 Symyx Technologies, Inc. High throughput crystallographic screening of materials
CA2453182A1 (en) * 2001-07-10 2003-01-23 Meredith L. Greene Crystalline thiazine oxazolidinones
CN100364991C (zh) * 2001-08-15 2008-01-30 法玛西雅厄普约翰美国公司 2,4-二甲基-1h-吡咯-3-甲酰胺衍生物的苹果酸盐的晶体、其制备方法和其组合物
WO2003077842A2 (en) * 2002-03-12 2003-09-25 Bristol-Myers Squibb Company Palatable oral suspension and method
WO2003093322A2 (en) * 2002-04-30 2003-11-13 The Population Council, Inc. Carrageenan based antimicrobial compositions
US8367098B2 (en) * 2002-04-30 2013-02-05 The Population Council, Inc. Unique combinations of antimicrobial compositions
EP1575951B1 (en) * 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en) 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
MXPA06000524A (es) * 2003-07-18 2006-08-11 Santarus Inc Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido.
DK1828167T3 (da) * 2004-06-04 2014-10-20 Debiopharm Int Sa Acrylamidderivater som antibiotiske midler
KR20080075027A (ko) * 2005-12-05 2008-08-13 아피늄 파마슈티컬스, 인크. Ｆａｂｉ 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물
JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
EP2125802A4 (en) 2007-02-16 2014-08-20 Debiopharm Int Sa SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS
AU2013279021C1 (en) 2012-06-19 2017-03-16 Debiopharm International Sa Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
RS61312B1 (sr) 2016-02-26 2021-02-26 Debiopharm Int Sa Lek za lečenje infekcija dijabetskog stopala
TN2021000159A1 (en) 2019-02-14 2023-04-04 Debiopharm Int Sa Afabicin formulation, method for making the same and uses thereof
SG11202113174SA (en) 2019-06-14 2021-12-30 Debiopharm Int Sa Medicament and use thereof for treating bacterial infections involving biofilm

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164402A (en) 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
US5266559A (en) 1989-10-27 1993-11-30 Firmenich S.A. Use of unsaturated macrocyclic lactones as perfuming ingredients
US5391763A (en) 1990-07-11 1995-02-21 Pfizer Inc. 3-aza-bicyclo[3.1.0]hexanes which are intermediates for anti-bacterial azabicyclo quinolone carboxylic acids
TW271400B (es) 1992-07-30 1996-03-01 Pfizer
DK0789697T3 (da) 1995-06-06 1998-10-19 Pfizer Krystalform af vandfrit 7-([1alfa, 5alfa, 6alfa,]-6-amino-3-azabicyclo[3.1.0]hex-3-yl)-6-fluor-1-(2,4-difluorphenyl)-1,4-d
US6080756A (en) * 1995-08-29 2000-06-27 Pfizer Inc. Polymorphs of the prodrug 6-N-(L-ALA-L-ALA)-trovafloxacin
WO1997007800A1 (en) * 1995-08-29 1997-03-06 Pfizer Inc. Zwitterionic forms of trovafloxacin
US6114531A (en) * 1998-07-28 2000-09-05 Pfizer Inc. Process for preparing quinolone and naphthyridone carboxylic acids

Also Published As

Publication number Publication date
JP3465820B2 (ja) 2003-11-10
EP1057828B1 (en) 2003-03-19
DE60001687T2 (de) 2003-12-18
JP2000344770A (ja) 2000-12-12
CA2311112A1 (en) 2000-12-04
EP1057828A2 (en) 2000-12-06
DE60001687D1 (de) 2003-04-24
US6239141B1 (en) 2001-05-29
PT1057828E (pt) 2003-07-31
DK1057828T3 (da) 2003-07-14
EP1057828A3 (en) 2001-05-16
BR0002577A (pt) 2001-01-02
ATE234835T1 (de) 2003-04-15

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