ATE234935T1 - Reduktion von ketongruppen - Google Patents

Reduktion von ketongruppen

Info

Publication number: ATE234935T1
Authority: AT; Austria
Prior art keywords: pct; compound; formula; produced; reduction
Prior art date: 1995-06-23

Application number

AT96920921T

Other languages

English (en)

Inventor

Christopher David Reeve

Original Assignee

Avecia Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-23

Filing date

1996-06-17

Publication date

2003-04-15

1996-06-17 Application filed by Avecia Ltd filed Critical Avecia Ltd

2003-04-15 Application granted granted Critical

2003-04-15 Publication of ATE234935T1 publication Critical patent/ATE234935T1/de

Links

150000002576 ketones Chemical group 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
241000235648 Pichia Species 0.000 abstract 2
241000223679 Beauveria Species 0.000 abstract 1
241000222120 Candida <Saccharomycetales> Species 0.000 abstract 1
235000014683 Hansenula anomala Nutrition 0.000 abstract 1
241000235649 Kluyveromyces Species 0.000 abstract 1
241000221961 Neurospora crassa Species 0.000 abstract 1
241000489470 Ogataea trehalophila Species 0.000 abstract 1
241000235006 Torulaspora Species 0.000 abstract 1
241000235063 Wickerhamomyces anomalus Species 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Separation Using Semi-Permeable Membranes (AREA)

AT96920921T 1995-06-23 1996-06-17 Reduktion von ketongruppen ATE234935T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9512837.7A GB9512837D0 (en)	1995-06-23	1995-06-23	reduction of ketone groups
PCT/GB1996/001422 WO1997000968A1 (en)	1995-06-23	1996-06-17	Reduction of ketone groups

Publications (1)

Publication Number	Publication Date
ATE234935T1 true ATE234935T1 (de)	2003-04-15

Family

ID=10776577

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96920921T ATE234935T1 (de)	1995-06-23	1996-06-17	Reduktion von ketongruppen

Country Status (12)

Country	Link
US (1)	US6001615A (de)
EP (1)	EP0833938B1 (de)
JP (1)	JP3580825B2 (de)
AT (1)	ATE234935T1 (de)
AU (1)	AU6230696A (de)
CA (1)	CA2221800C (de)
CZ (1)	CZ291886B6 (de)
DE (1)	DE69626820T2 (de)
DK (1)	DK0833938T3 (de)
ES (1)	ES2194995T3 (de)
GB (1)	GB9512837D0 (de)
WO (1)	WO1997000968A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1077212B1 (de) *	1998-04-30	2003-08-20	Kaneka Corporation	Verfahren zur herstellung von derivaten der 6-cyanomethyl-1,3-dioxan-4-essigsäure
PT1619191E (pt) *	1998-08-05	2010-12-21	Kaneka Corp	Processo de produção de derivados opticamente activos do ácido 2-[6-(hidroximetil)-1,3-dioxan-4-il]acético
DE19857302C2 (de) *	1998-12-14	2000-10-26	Forschungszentrum Juelich Gmbh	Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren, deren Salze und Ester
WO2001004336A1 (de)	1999-07-09	2001-01-18	Forschungszentrum Jülich GmbH	Verfahren zur reduktion von keto-carbonsäuren und deren estern
DE19937825B4 (de) *	1999-07-09	2005-08-11	Forschungszentrum Jülich GmbH	Verfahren zur Reduktion von Hydroxyketo-Carbonsäuren und deren Estern
JP4510351B2 (ja) *	1999-12-03	2010-07-21	株式会社カネカ	新規カルボニル還元酵素、その遺伝子、およびその利用法
GB0011120D0 (en) *	2000-05-09	2000-06-28	Avecia Ltd	Process
EP1365029A4 (de)	2001-02-02	2009-07-29	Mitsubishi Chem Corp	"verfahren zur darstellung von (3r,5s)-(e)-7- 2-cyclopropyl-4-(4-fluorphenyl)-chinolin-3-yl -3,5-dihydroxyhept-6-ensäureestern"
KR100451413B1 (ko) *	2001-12-28	2004-10-06	한국과학기술연구원	클루이베로마이시스 마르시아누스의 카르보닐 환원효소를이용한 카르보닐 화합물의 환원반응
US7132267B2 (en) *	2002-08-09	2006-11-07	Codexis, Inc.	Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters
WO2004015132A2 (en) *	2002-08-09	2004-02-19	Codexis, Inc.	Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
CA2535255A1 (en) *	2003-08-11	2005-02-24	Codexis, Inc.	Improved halohydrin dehalogenases and related polynucleotides
JP2007502124A (ja) *	2003-08-11	2007-02-08	コデクシス，インコーポレイテッド	改良ケトレダクターゼポリペプチドおよび関連ポリヌクレオチド
JP2007502114A (ja) *	2003-08-11	2007-02-08	コデクシス，インコーポレイテッド	改良されたグルコースデヒドロゲナーゼポリペプチドおよび関連ポリヌクレオチド
US7588928B2 (en) *	2003-08-11	2009-09-15	Codexis, Inc.	Halohydrin dehalogenases and related polynucleotides
US7541171B2 (en) *	2003-08-11	2009-06-02	Codexis, Inc.	Halohydrin dehalogenases and related polynucleotides
AT503017B1 (de) *	2005-12-19	2007-07-15	Iep Gmbh	Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen
DE102006010994A1 (de) *	2006-03-09	2007-09-13	Wacker Chemie Ag	Verfahren zur enzymatischen Herstellung von chiralen Alkoholen
WO2008042876A2 (en)	2006-10-02	2008-04-10	Codexis, Inc.	Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor
WO2008059366A2 (en) *	2006-11-17	2008-05-22	Pfizer Products Inc.	Process for the preparation of cis-1, 3-diols from the corresponding beta-hydroxy ketones employing microbial ketone reductases
EP2198018B1 (de)	2007-09-13	2013-11-20	Codexis, Inc.	Ketoreduktase-polypeptide zur reduktion von acetophenonen
WO2010080635A2 (en) *	2008-12-18	2010-07-15	Codexis, Inc.	Recombinant halohydrin dehalogenase polypeptides
MX2012009362A (es)	2010-02-12	2013-05-28	Gevo Inc	Microorganismos de levadura con acumulación reducida de subproductos para una producción mejorada de combustibles, químicos y aminoácidos.
CN102676596A (zh) *	2011-03-16	2012-09-19	苏州国镝医药科技有限公司	生物酶手性合成立普妥中间体ats-7

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3724197A1 (de) *	1987-07-22	1989-02-02	Merck Patent Gmbh	Verfahren zur reduktion von ketonen
US5003080A (en) *	1988-02-22	1991-03-26	Warner-Lambert Company	Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
US5155251A (en) *	1991-10-11	1992-10-13	Warner-Lambert Company	Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate
US5324662A (en) *	1992-05-15	1994-06-28	E. R. Squibb & Sons, Inc.	Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters

1995
- 1995-06-23 GB GBGB9512837.7A patent/GB9512837D0/en active Pending
1996
- 1996-06-17 DE DE69626820T patent/DE69626820T2/de not_active Expired - Fee Related
- 1996-06-17 AU AU62306/96A patent/AU6230696A/en not_active Abandoned
- 1996-06-17 CZ CZ19974129A patent/CZ291886B6/cs not_active IP Right Cessation
- 1996-06-17 ES ES96920921T patent/ES2194995T3/es not_active Expired - Lifetime
- 1996-06-17 AT AT96920921T patent/ATE234935T1/de not_active IP Right Cessation
- 1996-06-17 WO PCT/GB1996/001422 patent/WO1997000968A1/en not_active Ceased
- 1996-06-17 DK DK96920921T patent/DK0833938T3/da active
- 1996-06-17 US US08/981,731 patent/US6001615A/en not_active Expired - Fee Related
- 1996-06-17 CA CA002221800A patent/CA2221800C/en not_active Expired - Fee Related
- 1996-06-17 EP EP96920921A patent/EP0833938B1/de not_active Expired - Lifetime
- 1996-06-17 JP JP53201396A patent/JP3580825B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0833938A1 (de)	1998-04-08
AU6230696A (en)	1997-01-22
US6001615A (en)	1999-12-14
WO1997000968A1 (en)	1997-01-09
GB9512837D0 (en)	1995-08-23
CZ412997A3 (cs)	1998-03-18
CA2221800A1 (en)	1997-01-09
CZ291886B6 (cs)	2003-06-18
ES2194995T3 (es)	2003-12-01
JP3580825B2 (ja)	2004-10-27
CA2221800C (en)	2008-10-28
EP0833938B1 (de)	2003-03-19
JPH11507204A (ja)	1999-06-29
DE69626820D1 (de)	2003-04-24
DK0833938T3 (da)	2003-07-14
DE69626820T2 (de)	2004-02-12

Similar Documents

Publication	Publication Date	Title
ATE234935T1 (de)	2003-04-15	Reduktion von ketongruppen
ATE361364T1 (de)	2007-05-15	Antikörper gegen die ed-b domäne von fibronektin, ihre herstellung und verwendungen
DE69830574D1 (de)	2005-07-21	Verbesserte verfahren zur herstellung von vernetzt verbrückten macropolycyclen
ATE260103T1 (de)	2004-03-15	Ortho-anthranilamide derivate als antikoagulantien
ATE194601T1 (de)	2000-07-15	Verfahren zur herstellung von pyrimidinverbindungen
DK0923568T3 (da)	2003-04-07	Hidtil ukendte benzofuran-4-carboxamider
FI872365A0 (fi)	1987-05-27	Trans-6-(2-(3- eller 4-karboxamido -substituerad pyrrol-1-yl)alkyl)-4-hydroxipyran-2-oner saosom kolesterolsyntesinhibitorer.
ATE354468T1 (de)	2007-03-15	Verfahren zur herstellung von verpackungsmaterial
ATE322473T1 (de)	2006-04-15	Verfahren zur herstellung von verbindungen geeignet als zwischenprodukte
ATE203670T1 (de)	2001-08-15	Verwendung von östrogenantagonisten und - agonisten zur hemmung pathologischer zustände
TR199800773T2 (xx)	1998-08-21	Trombin inhibit�rleri.
ES2172083T3 (es)	2002-09-16	Composicion limpiadora antibacteriana ultrasuave para uso frecuente.
EA200201071A1 (ru)	2003-04-24	Циклопентилзамещенные производные глутарамида в качестве ингибиторов нейтральной эндопептидазы
ATE255582T1 (de)	2003-12-15	Verfahren zur synthese von 4-und/oder 5-(di) substituierten 2-aminoimidazolen aus 2- aminoimidazolen und aldehyden
ES2102038T3 (es)	1997-07-16	Polimerizacion de lignina a ph alcalino.
TR200003056T2 (tr)	2001-02-21	Heterosiklik olarak ikame edilmiş amidler, üretimi ve kullanımı
DE59605649D1 (de)	2000-08-31	Polymerisationsfähige derivate von polyamiden
ATE225771T1 (de)	2002-10-15	Prostaglandin-pharmazeutische-zusammensetzungen
DE59711834D1 (de)	2004-09-09	Racemattrennung von ketamin
ATE231128T1 (de)	2003-02-15	Verbindungen mit kondensierten ringen, verfahren zu ihrer herstellung und ihre anwendung
ATE158579T1 (de)	1997-10-15	Verfahren zur herstellung von (3r,5s)6-hydroxy- 3,5-0-isopropyliden-3,5-dihydroxy-hexansäure- tert.-butylester
ATE218060T1 (de)	2002-06-15	Zusammenstellungen die beta-amyloid protein bedingte zytotoxizität verhindern
DE69706382D1 (de)	2001-10-04	Verfahren zur herstellung von 2,2'-bipyrrolyl-pyrromethen-derivaten (prodigiosine)
ATE210662T1 (de)	2001-12-15	Verfahren zur herstellung von epoxiden
DE69604050D1 (de)	1999-10-07	Verfahren zur herstellung von 2-(substituierten benzoyl)-1,3 cyclohexanedionen

Legal Events

Date	Code	Title	Description
2003-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties