ATE235259T1 - Verfahren zur herstellung von kontrastmitteln - Google Patents

Verfahren zur herstellung von kontrastmitteln

Info

Publication number
ATE235259T1
ATE235259T1 AT98939753T AT98939753T ATE235259T1 AT E235259 T1 ATE235259 T1 AT E235259T1 AT 98939753 T AT98939753 T AT 98939753T AT 98939753 T AT98939753 T AT 98939753T AT E235259 T1 ATE235259 T1 AT E235259T1
Authority
AT
Austria
Prior art keywords
gas
containing vesicles
aqueous dispersion
dispersion
contrast agents
Prior art date
Application number
AT98939753T
Other languages
English (en)
Inventor
Ingrid Henriksen
Vera Kasparkova
Arnfinn Andersen
Anne Kjersti Fahlvik
Liv Ingrid Odegardstuen
Original Assignee
Amersham Health As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Health As filed Critical Amersham Health As
Application granted granted Critical
Publication of ATE235259T1 publication Critical patent/ATE235259T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98939753T 1997-08-19 1998-08-19 Verfahren zur herstellung von kontrastmitteln ATE235259T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9717542.6A GB9717542D0 (en) 1997-08-19 1997-08-19 Process
PCT/GB1998/002490 WO1999008715A1 (en) 1997-08-19 1998-08-19 Process for preparing contrast agents

Publications (1)

Publication Number Publication Date
ATE235259T1 true ATE235259T1 (de) 2003-04-15

Family

ID=10817701

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98939753T ATE235259T1 (de) 1997-08-19 1998-08-19 Verfahren zur herstellung von kontrastmitteln

Country Status (10)

Country Link
US (1) US6509004B1 (de)
EP (1) EP1007102B1 (de)
JP (1) JP5047415B2 (de)
AT (1) ATE235259T1 (de)
AU (1) AU8816098A (de)
DE (1) DE69812645T2 (de)
GB (1) GB9717542D0 (de)
NO (1) NO20000621L (de)
WO (1) WO1999008715A1 (de)
ZA (1) ZA987480B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810051D0 (en) * 1998-05-11 1998-07-08 Nycomed Imaging As Contrast media
GB0811856D0 (en) * 2008-06-27 2008-07-30 Ucl Business Plc Magnetic microbubbles, methods of preparing them and their uses
GB201405735D0 (en) * 2014-03-31 2014-05-14 Ge Healthcare As Ultrasound precursor preparation method
GB201411423D0 (en) * 2014-06-26 2014-08-13 Ge Healthcare As Lipid sterilisation method
EP4154915A1 (de) 2014-12-31 2023-03-29 Lantheus Medical Imaging, Inc. Lipidverkapselte gasmikrosphärenzusammensetzungen und zugehörige verfahren
KR20180133527A (ko) 2016-05-04 2018-12-14 랜티우스 메디컬 이메징, 인크. 초음파 조영제의 제조 방법 및 장치
US9789210B1 (en) * 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
WO1994001140A1 (de) * 1992-07-03 1994-01-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Echokontrastmittelzubereitung
US5798091A (en) * 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
GB9423419D0 (en) * 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
DE19510690A1 (de) * 1995-03-14 1996-09-19 Schering Ag Polymere Nano- und/oder Mikropartikel, Verfahren zu deren Herstellung, sowie Verwendung in medizinischen Diagnostik und Therapie
US5997898A (en) * 1995-06-06 1999-12-07 Imarx Pharmaceutical Corp. Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
GB9511488D0 (en) * 1995-06-07 1995-08-02 Nycomed Imaging As Improvements in or relating to contrast agents
US5601085A (en) * 1995-10-02 1997-02-11 Nycomed Imaging As Ultrasound imaging
NZ331372A (en) * 1996-02-19 2000-01-28 Nycomed Imaging As freeze-dried vesicle containing a thermally stabilized ultrasound contrast agent
ES2197986T3 (es) * 1996-02-19 2004-01-16 Amersham Health As Mejoras introducidas en o relacionadas con agentes de contraste.
DE19611769A1 (de) * 1996-03-14 1997-09-18 Schering Ag Mikropartikel, Verfahren zu deren Herstellung, sowie deren Verwendung in der Ultraschall Diagnostik
US6120751A (en) * 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same

Also Published As

Publication number Publication date
JP5047415B2 (ja) 2012-10-10
JP2001515054A (ja) 2001-09-18
DE69812645D1 (de) 2003-04-30
US6509004B1 (en) 2003-01-21
GB9717542D0 (en) 1997-10-22
EP1007102B1 (de) 2003-03-26
AU8816098A (en) 1999-03-08
EP1007102A1 (de) 2000-06-14
NO20000621D0 (no) 2000-02-08
ZA987480B (en) 2000-02-21
DE69812645T2 (de) 2004-03-04
NO20000621L (no) 2000-03-10
WO1999008715A1 (en) 1999-02-25

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