ATE236628T1 - Fenofibrathaltige neue galenische arzneizusammensetzungen und ihre verwendung - Google Patents
Fenofibrathaltige neue galenische arzneizusammensetzungen und ihre verwendungInfo
- Publication number
- ATE236628T1 ATE236628T1 AT96401614T AT96401614T ATE236628T1 AT E236628 T1 ATE236628 T1 AT E236628T1 AT 96401614 T AT96401614 T AT 96401614T AT 96401614 T AT96401614 T AT 96401614T AT E236628 T1 ATE236628 T1 AT E236628T1
- Authority
- AT
- Austria
- Prior art keywords
- fenofibrates
- compositions containing
- medicinal compositions
- new galenic
- galenic
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 239000001828 Gelatine Substances 0.000 abstract 1
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 abstract 1
- 229940075557 diethylene glycol monoethyl ether Drugs 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- YMTINGFKWWXKFG-UHFFFAOYSA-N fenofibrate Chemical compound C1=CC(OC(C)(C)C(=O)OC(C)C)=CC=C1C(=O)C1=CC=C(Cl)C=C1 YMTINGFKWWXKFG-UHFFFAOYSA-N 0.000 abstract 1
- 229960002297 fenofibrate Drugs 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000007901 soft capsule Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9509142A FR2737121B1 (fr) | 1995-07-27 | 1995-07-27 | Nouvelles formulations galeniques du fenofibrate et leurs applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE236628T1 true ATE236628T1 (de) | 2003-04-15 |
Family
ID=9481448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96401614T ATE236628T1 (de) | 1995-07-27 | 1996-07-19 | Fenofibrathaltige neue galenische arzneizusammensetzungen und ihre verwendung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5827536A (de) |
| EP (1) | EP0757911B1 (de) |
| JP (1) | JPH09328427A (de) |
| KR (1) | KR970005285A (de) |
| AT (1) | ATE236628T1 (de) |
| CA (1) | CA2181422A1 (de) |
| DE (2) | DE757911T1 (de) |
| ES (1) | ES2110377T1 (de) |
| FR (1) | FR2737121B1 (de) |
| GR (1) | GR980300014T1 (de) |
| HU (1) | HUP9602056A3 (de) |
| ZA (1) | ZA966067B (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7255877B2 (en) | 1996-08-22 | 2007-08-14 | Jagotec Ag | Fenofibrate microparticles |
| RO120603B1 (ro) | 1996-08-22 | 2006-05-30 | Research Triangle Pharmaceuticals Ltd. | Compoziţie conţinând microparticule de substanţe insolubile în apă şi procedeu de preparare |
| US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
| US6152991A (en) | 1997-04-17 | 2000-11-28 | Praxair Technology, Inc. | Multilayer adsorbent beds for PSA gas separation |
| AU1809499A (en) * | 1997-12-10 | 1999-06-28 | Awadhesh K. Mishra | Self-emulsifying fenofibrate formulations |
| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| WO1999061001A1 (en) | 1998-05-29 | 1999-12-02 | Rtp Pharma Inc. | Thermoprotected microparticle compositions and process for terminal steam sterilization thereof |
| US7097849B2 (en) | 1998-08-19 | 2006-08-29 | Jagotec Ag | Injectable aqueous dispersions of propofol |
| US6264960B1 (en) | 1998-11-10 | 2001-07-24 | Sander J. Robins | Treatment of vascular events using lipid-modifying compositions |
| WO2000030616A1 (en) | 1998-11-20 | 2000-06-02 | Rtp Pharma Inc. | Dispersible phospholipid stabilized microparticles |
| US6838091B2 (en) * | 1998-12-18 | 2005-01-04 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
| US7014864B1 (en) | 1998-12-18 | 2006-03-21 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
| US6814977B1 (en) | 1998-12-18 | 2004-11-09 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
| DE19858789A1 (de) | 1998-12-18 | 2000-06-21 | Bayer Ag | Kombination von Cerivastatin und Fibraten |
| US6719999B2 (en) * | 1999-03-31 | 2004-04-13 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
| CA2270306C (en) * | 1999-04-27 | 2000-09-26 | Bernard Charles Sherman | Pharmaceutical compositions comprising co-micronized fenofibrate |
| US6372251B2 (en) | 1999-06-11 | 2002-04-16 | Abbott Laboratories | Formulations comprising lipid-regulating agents |
| US6982281B1 (en) | 2000-11-17 | 2006-01-03 | Lipocine Inc | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
| FR2803203B1 (fr) * | 1999-12-31 | 2002-05-10 | Fournier Ind & Sante | Nouvelles formulations galeniques du fenofibrate |
| CA2407027C (en) | 2000-04-20 | 2011-02-15 | Rtp Pharma Inc. | Improved water-insoluble drug particle process |
| US6531158B1 (en) | 2000-08-09 | 2003-03-11 | Impax Laboratories, Inc. | Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
| NZ525306A (en) * | 2000-09-20 | 2004-11-26 | Skyepharma Canada Inc | Spray drying process and compositions of fenofibrate |
| US8586094B2 (en) | 2000-09-20 | 2013-11-19 | Jagotec Ag | Coated tablets |
| FR2819720B1 (fr) * | 2001-01-22 | 2004-03-12 | Fournier Lab Sa | Nouveaux comprimes de fenofibrate |
| US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| PT1355644E (pt) | 2001-01-26 | 2006-11-30 | Schering Corp | Utilização de compostos azetidinona substituídos para o tratamento de sitosterolemia |
| ES2274013T3 (es) | 2001-01-26 | 2007-05-16 | Schering Corporation | Combinaciones de activador(es) del receptor activado por el proliferador de los peroxisomas (ppar) e inhibidor(es)m de la absorcion de estelores y tratamientos para trastornos vasculares. |
| CN1273112C (zh) * | 2001-02-22 | 2006-09-06 | 斯凯伊药品加拿大公司 | 具有减少进食-禁食作用的贝特-它汀组合 |
| JPWO2002069957A1 (ja) * | 2001-03-01 | 2004-07-02 | グレラン製薬株式会社 | フェノフィブラート含有組成物 |
| ITMI20011338A1 (it) * | 2001-06-26 | 2002-12-26 | Farmatron Ltd | Composizioni farmaceutiche orali a rilascio immediato del principio attivo |
| JP2005504091A (ja) | 2001-09-21 | 2005-02-10 | シェーリング コーポレイション | ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置 |
| US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| DE60222803T2 (de) * | 2001-12-21 | 2008-07-17 | Supernus Pharmaceuticals, Inc. | Orale kapselformulierung mit verbesserter physikalischer stabilität |
| US20030212138A1 (en) * | 2002-01-14 | 2003-11-13 | Pharmacia Corporation | Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor |
| US20030220374A1 (en) * | 2002-01-14 | 2003-11-27 | Pharmacia Corporation | Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors |
| US20040005339A1 (en) * | 2002-06-28 | 2004-01-08 | Shojaei Amir H. | Formulations of fenofibrate and/or fenofibrate derivatives with improved oral bioavailability |
| US7560449B2 (en) | 2002-11-06 | 2009-07-14 | Schering Corporation | Methods and therapeutic combinations for the treatment of demyelination |
| BRPI0407181A (pt) * | 2003-02-03 | 2006-02-07 | Novartis Ag | Formulação farmacêutica |
| WO2004081003A1 (en) | 2003-03-07 | 2004-09-23 | Schering Corporation | Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholeterolemia |
| ES2311806T3 (es) | 2003-03-07 | 2009-02-16 | Schering Corporation | Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| EP1606287B1 (de) * | 2003-03-07 | 2013-10-02 | Merck Sharp & Dohme Corp. | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
| US8026281B2 (en) | 2004-10-14 | 2011-09-27 | Lupin Atlantis Holdings, S.A. | Treating metabolic syndrome with fenofibrate |
| KR101356335B1 (ko) * | 2004-12-06 | 2014-02-06 | 릴라이언트 파마슈티컬스 인코퍼레이티드 | 지질 치료를 위한 오메가-3 지방산 및 이상지질혈증 제제 |
| CA2589656A1 (en) * | 2004-12-06 | 2006-06-15 | Reliant Pharmaceuticals, Inc. | Stable compositions of fenofibrate with fatty acid esters |
| BRPI0607569A2 (pt) * | 2005-03-08 | 2009-09-15 | Reliant Pharmaceuticals Inc | composição farmacêutica compreendendo estatina e ácidos graxos Èmega-3, na forma de dosagem unitária |
| CA2600407A1 (en) * | 2005-03-30 | 2006-10-12 | Teva Pharmaceutical Industries Ltd. | Fibrate compositions containing a surfactant mixture of peg-600 and poloxamer 407 |
| EP1707197A1 (de) | 2005-03-30 | 2006-10-04 | Teva Pharmaceutical Industries Ltd. | Zusammensetzungen, welche Fenofibrat und eine Tensidmischung beinhaltet |
| US20070148233A1 (en) * | 2005-12-28 | 2007-06-28 | Lerner E I | Pharmaceutical formulations of fenofibrate having improved bioavailability |
| CA2601372A1 (en) * | 2005-03-30 | 2006-10-12 | Teva Pharmaceutical Industries Ltd. | Improved formulations of fenofibrate containing menthol or peg/poloxamer |
| US20070015833A1 (en) * | 2005-07-18 | 2007-01-18 | Moshe Flashner-Barak | Formulations of fenofibrate containing menthol |
| DE602005014258D1 (de) | 2005-12-28 | 2009-06-10 | Teva Pharma | Pharmazeutische Formulierungen mit Fenofibrat mit verbesserter Bioverfügbarkeit |
| RU2011103066A (ru) * | 2008-07-03 | 2012-08-10 | Панацеа Биотек Лимитед (In) | Состав фенофибрата с улучшенной биодоступностью при пероральном введении |
| US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
| US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| CN113384569A (zh) | 2013-09-18 | 2021-09-14 | 乔治城大学 | 用非诺贝特及其类似物治疗神经退行性疾病 |
| US20170246187A1 (en) | 2014-08-28 | 2017-08-31 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
| WO2016033556A1 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS |
| US20160361322A1 (en) | 2015-06-15 | 2016-12-15 | Lipocine Inc. | Composition and method for oral delivery of androgen prodrugs |
| US20180147215A1 (en) | 2016-11-28 | 2018-05-31 | Lipocine Inc. | Oral testosterone undecanoate therapy |
| JP2021531348A (ja) | 2018-07-20 | 2021-11-18 | リポシン,インク. | 肝臓病 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2494112B1 (de) * | 1980-11-19 | 1986-01-10 | Laruelle Claude | |
| FR2602423B1 (fr) * | 1986-08-08 | 1989-05-05 | Ethypharm Sa | Procede de preparation d'un medicament a base de fenofibrate, medicament obtenu par ce procede |
| FR2617047B1 (fr) * | 1987-06-23 | 1991-05-10 | Sanofi Sa | Composition de gelatine resistant au tannage, capsules a base de cette composition et leur application pharmaceutique, notamment au fenofibrate |
| FR2627696B1 (fr) * | 1988-02-26 | 1991-09-13 | Fournier Innovation Synergie | Nouvelle forme galenique du fenofibrate |
-
1995
- 1995-07-27 FR FR9509142A patent/FR2737121B1/fr not_active Expired - Fee Related
-
1996
- 1996-07-17 ZA ZA966067A patent/ZA966067B/xx unknown
- 1996-07-17 CA CA002181422A patent/CA2181422A1/fr not_active Abandoned
- 1996-07-19 ES ES96401614T patent/ES2110377T1/es active Pending
- 1996-07-19 EP EP96401614A patent/EP0757911B1/de not_active Revoked
- 1996-07-19 AT AT96401614T patent/ATE236628T1/de not_active IP Right Cessation
- 1996-07-19 DE DE0757911T patent/DE757911T1/de active Pending
- 1996-07-19 DE DE69627253T patent/DE69627253T2/de not_active Expired - Fee Related
- 1996-07-25 US US08/672,852 patent/US5827536A/en not_active Expired - Fee Related
- 1996-07-25 JP JP8196323A patent/JPH09328427A/ja active Pending
- 1996-07-26 KR KR1019960030637A patent/KR970005285A/ko not_active Ceased
- 1996-07-26 HU HU9602056A patent/HUP9602056A3/hu unknown
-
1998
- 1998-03-31 GR GR980300014T patent/GR980300014T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69627253T2 (de) | 2004-01-29 |
| ES2110377T1 (es) | 1998-02-16 |
| GR980300014T1 (en) | 1998-03-31 |
| DE757911T1 (de) | 1998-03-26 |
| FR2737121B1 (fr) | 1997-10-03 |
| FR2737121A1 (fr) | 1997-01-31 |
| ZA966067B (en) | 1997-04-07 |
| CA2181422A1 (fr) | 1997-01-28 |
| JPH09328427A (ja) | 1997-12-22 |
| US5827536A (en) | 1998-10-27 |
| EP0757911A1 (de) | 1997-02-12 |
| EP0757911B1 (de) | 2003-04-09 |
| HU9602056D0 (en) | 1996-09-30 |
| HUP9602056A3 (en) | 2000-09-28 |
| KR970005285A (ko) | 1997-02-19 |
| HUP9602056A2 (en) | 1997-06-30 |
| DE69627253D1 (de) | 2003-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |