ATE236922T1 - Natürliche antitumor- oder antivirale substanzen und ihre anwendung - Google Patents

Natürliche antitumor- oder antivirale substanzen und ihre anwendung

Info

Publication number
ATE236922T1
ATE236922T1 AT98923089T AT98923089T ATE236922T1 AT E236922 T1 ATE236922 T1 AT E236922T1 AT 98923089 T AT98923089 T AT 98923089T AT 98923089 T AT98923089 T AT 98923089T AT E236922 T1 ATE236922 T1 AT E236922T1
Authority
AT
Austria
Prior art keywords
formula
pharmaceutically acceptable
acceptable salt
represented
present
Prior art date
Application number
AT98923089T
Other languages
English (en)
Inventor
Tsuneatsu Mori
Maowu Guo
Etsuko Mori
Original Assignee
Itochu Techno Chem Inc
Tsuneatsu Mori
Mori Takahide
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Itochu Techno Chem Inc, Tsuneatsu Mori, Mori Takahide filed Critical Itochu Techno Chem Inc
Application granted granted Critical
Publication of ATE236922T1 publication Critical patent/ATE236922T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98923089T 1997-06-03 1998-06-02 Natürliche antitumor- oder antivirale substanzen und ihre anwendung ATE236922T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15932197 1997-06-03
PCT/JP1998/002438 WO1998055493A1 (fr) 1997-06-03 1998-06-02 Substances naturelles antitumorales ou antivirales et leur utilisation

Publications (1)

Publication Number Publication Date
ATE236922T1 true ATE236922T1 (de) 2003-04-15

Family

ID=15691258

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98923089T ATE236922T1 (de) 1997-06-03 1998-06-02 Natürliche antitumor- oder antivirale substanzen und ihre anwendung

Country Status (12)

Country Link
US (1) US6498149B1 (de)
EP (1) EP0997473B1 (de)
JP (1) JP3193061B2 (de)
KR (1) KR100404630B1 (de)
CN (2) CN1292073C (de)
AT (1) ATE236922T1 (de)
AU (1) AU754370B2 (de)
CA (1) CA2294158C (de)
DE (1) DE69813231T2 (de)
ES (1) ES2194320T3 (de)
RU (1) RU2205010C2 (de)
WO (1) WO1998055493A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1098355C (zh) * 2000-09-12 2003-01-08 华东理工大学 一种乙酰短杆菌及以该菌种为酶源制备5－氟尿苷的方法
SI1355916T1 (sl) * 2001-01-22 2007-04-30 Merck & Co Inc Nukleozidni derivati kot inhibitorji RNA-odvisne RNA virusne polimeraze
RU2300384C2 (ru) * 2005-01-31 2007-06-10 Юрий Евгеньевич Бурда Вещество, обладающее противовоспалительной, иммуномодулирующей и ранозаживляющей активностью
ATE482690T1 (de) * 2005-12-14 2010-10-15 Hoffmann La Roche Hcv-prodrug-formulierung
CA2654371A1 (en) 2006-06-27 2008-01-03 Biovitrum Ab (Publ) Therapeutic compounds
ES2361886T3 (es) 2006-06-27 2011-06-24 Cbt Development Limited Profármacos adenosina acetil 2',3'-metilideno novedosos para uso como profármacos para agonistas del receptor adenosina.
BRPI0817234A2 (pt) * 2007-09-26 2014-09-30 Sinai School Medicine Análogos de azacitidina e seus usos
FI20096394A0 (fi) 2009-12-23 2009-12-23 Valtion Teknillinen Tunkeutumisen havaitseminen viestintäverkoissa

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071680A (en) * 1976-12-20 1978-01-31 Hoffmann-La Roche Inc. 5'-Deoxy-5-fluoropyrimidine nucleosides
JPS54140710A (en) * 1978-03-10 1979-11-01 Mitsui Toatsu Chem Inc Anti-tumor substance and its preparation
JPS54129131A (en) * 1978-03-27 1979-10-06 Taiho Pharmaceutical Co Ltd Antiimalignant tumor agent composition
JPS5564518A (en) * 1978-11-07 1980-05-15 Taiho Yakuhin Kogyo Kk Carcinostatic composition
EP0202056B1 (de) * 1985-05-07 1989-08-30 Teijin Limited Antitumormittel
JPS61291595A (ja) * 1985-06-19 1986-12-22 Ajinomoto Co Inc ２′−ｏ−メチル化ｒｎａの製造法
JPS6214794A (ja) * 1985-07-09 1987-01-23 Ajinomoto Co Inc 発酵法によるグアノシン及び／またはイノシンの製造法
JPS6223725A (ja) 1985-07-24 1987-01-31 Sekisui Plastics Co Ltd 熱可塑性樹脂発泡体の製造装置
JPS6223723A (ja) 1985-07-24 1987-01-31 Canon Inc 射出圧縮成形方法
US5470838A (en) * 1987-10-28 1995-11-28 Pro-Neuron, Inc. Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine
JPH01125325A (ja) * 1987-11-11 1989-05-17 Agency Of Ind Science & Technol 抗腫瘍剤
JP2926409B2 (ja) * 1989-05-22 1999-07-28 株式会社林原生物化学研究所 癌転移抑制因子の製造方法
US5200514A (en) 1990-01-19 1993-04-06 University Of Georgia Research Foundation, Inc. Synthesis of 2'-deoxypyrimidine nucleosides
JPH0695946B2 (ja) * 1991-01-23 1994-11-30 日本製紙株式会社 ウリジンの製造法
US5580973A (en) * 1994-01-07 1996-12-03 Lee-Ruff; Edward Process for preparing optically active nucleosides from chiral cyclobutanones

Also Published As

Publication number Publication date
HK1029121A1 (en) 2001-03-23
AU754370B2 (en) 2002-11-14
CA2294158A1 (en) 1998-12-10
RU2205010C2 (ru) 2003-05-27
KR20010029544A (ko) 2001-04-06
CN1616671A (zh) 2005-05-18
US6498149B1 (en) 2002-12-24
HK1077847A1 (en) 2006-02-24
AU7549098A (en) 1998-12-21
ES2194320T3 (es) 2003-11-16
EP0997473A4 (de) 2001-01-03
KR100404630B1 (ko) 2003-11-07
JP3193061B2 (ja) 2001-07-30
CN1261372A (zh) 2000-07-26
DE69813231D1 (de) 2003-05-15
DE69813231T2 (de) 2003-12-04
EP0997473B1 (de) 2003-04-09
CN1195769C (zh) 2005-04-06
CN1292073C (zh) 2006-12-27
WO1998055493A1 (fr) 1998-12-10
CA2294158C (en) 2004-11-23
EP0997473A1 (de) 2000-05-03

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