ATE236990T1 - Verfahren zur herstellung von optisch aktiven alpha-aminonitrilen - Google Patents
Verfahren zur herstellung von optisch aktiven alpha-aminonitrilenInfo
- Publication number
- ATE236990T1 ATE236990T1 AT99962574T AT99962574T ATE236990T1 AT E236990 T1 ATE236990 T1 AT E236990T1 AT 99962574 T AT99962574 T AT 99962574T AT 99962574 T AT99962574 T AT 99962574T AT E236990 T1 ATE236990 T1 AT E236990T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- aminonitrile
- enantiomers
- acylase
- chosen
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 4
- 108010026809 Peptide deformylase Proteins 0.000 abstract 3
- 239000002184 metal Substances 0.000 abstract 2
- 229910052751 metal Inorganic materials 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229910052759 nickel Inorganic materials 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- 238000006170 formylation reaction Methods 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 230000000737 periodic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98204370A EP1013773A1 (de) | 1998-12-22 | 1998-12-22 | Verfahren zur Herstellung von optisch aktiven Alpha-Aminonitrilen |
| PCT/NL1999/000782 WO2000037668A1 (en) | 1998-12-22 | 1999-12-17 | Process for the preparation of optically active alpha-aminonitriles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE236990T1 true ATE236990T1 (de) | 2003-04-15 |
Family
ID=8234515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99962574T ATE236990T1 (de) | 1998-12-22 | 1999-12-17 | Verfahren zur herstellung von optisch aktiven alpha-aminonitrilen |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1013773A1 (de) |
| JP (1) | JP2002533091A (de) |
| AT (1) | ATE236990T1 (de) |
| AU (1) | AU1898000A (de) |
| DE (1) | DE69906802T2 (de) |
| DK (1) | DK1141369T3 (de) |
| ES (1) | ES2196900T3 (de) |
| PT (1) | PT1141369E (de) |
| WO (1) | WO2000037668A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1352894A1 (de) | 2002-04-09 | 2003-10-15 | DSM IP Assets B.V. | Verfahren zur Herstellung von Enantiomer-angereicherten Verbindungen |
| US7067291B2 (en) | 2002-12-20 | 2006-06-27 | Pfizer Inc. | Biocatalytic preparation of enantiomerically enriched aminopentanenitrile |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929570A1 (de) * | 1989-09-06 | 1991-03-07 | Degussa | Mikrobiologisch hergestellte n-acyl-l-prolin-acylase, verfahren zu ihrer gewinnung und ihre verwendung |
-
1998
- 1998-12-22 EP EP98204370A patent/EP1013773A1/de not_active Withdrawn
-
1999
- 1999-12-17 ES ES99962574T patent/ES2196900T3/es not_active Expired - Lifetime
- 1999-12-17 AU AU18980/00A patent/AU1898000A/en not_active Abandoned
- 1999-12-17 PT PT99962574T patent/PT1141369E/pt unknown
- 1999-12-17 DK DK99962574T patent/DK1141369T3/da active
- 1999-12-17 AT AT99962574T patent/ATE236990T1/de not_active IP Right Cessation
- 1999-12-17 JP JP2000589721A patent/JP2002533091A/ja active Pending
- 1999-12-17 DE DE69906802T patent/DE69906802T2/de not_active Expired - Fee Related
- 1999-12-17 WO PCT/NL1999/000782 patent/WO2000037668A1/en not_active Ceased
- 1999-12-17 EP EP99962574A patent/EP1141369B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1141369E (pt) | 2003-08-29 |
| AU1898000A (en) | 2000-07-12 |
| DE69906802T2 (de) | 2003-12-24 |
| EP1141369A1 (de) | 2001-10-10 |
| DK1141369T3 (da) | 2003-08-04 |
| JP2002533091A (ja) | 2002-10-08 |
| EP1141369B1 (de) | 2003-04-09 |
| EP1013773A1 (de) | 2000-06-28 |
| WO2000037668A1 (en) | 2000-06-29 |
| ES2196900T3 (es) | 2003-12-16 |
| DE69906802D1 (de) | 2003-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1141369 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |