ATE237330T1 - Verabreichung von nikotin im dickdarm zur behandlung von entzündlicher eingeweidenerkrankung - Google Patents
Verabreichung von nikotin im dickdarm zur behandlung von entzündlicher eingeweidenerkrankungInfo
- Publication number
- ATE237330T1 ATE237330T1 AT97904516T AT97904516T ATE237330T1 AT E237330 T1 ATE237330 T1 AT E237330T1 AT 97904516 T AT97904516 T AT 97904516T AT 97904516 T AT97904516 T AT 97904516T AT E237330 T1 ATE237330 T1 AT E237330T1
- Authority
- AT
- Austria
- Prior art keywords
- nicotine
- colon
- administration
- inflammatory
- treatment
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 4
- 229960002715 nicotine Drugs 0.000 title abstract 4
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title abstract 4
- 210000001072 colon Anatomy 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/605,319 US5846983A (en) | 1996-02-09 | 1996-02-09 | Colonic delivery of nicotine to treat inflammatory bowel disease |
| PCT/GB1997/000369 WO1997028801A1 (en) | 1996-02-09 | 1997-02-07 | Colonic delivery of nicotine to treat inflammatory bowel disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237330T1 true ATE237330T1 (de) | 2003-05-15 |
Family
ID=24423169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97904516T ATE237330T1 (de) | 1996-02-09 | 1997-02-07 | Verabreichung von nikotin im dickdarm zur behandlung von entzündlicher eingeweidenerkrankung |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5846983A (de) |
| EP (1) | EP0893998B2 (de) |
| JP (1) | JP4283340B2 (de) |
| KR (1) | KR100458636B1 (de) |
| CN (1) | CN1127340C (de) |
| AT (1) | ATE237330T1 (de) |
| AU (1) | AU718971C (de) |
| CA (1) | CA2246235C (de) |
| CZ (1) | CZ293616B6 (de) |
| DE (1) | DE69720985T3 (de) |
| DK (1) | DK0893998T4 (de) |
| ES (1) | ES2196303T5 (de) |
| HU (1) | HUP9900950A3 (de) |
| MX (1) | MX9806354A (de) |
| MY (1) | MY122023A (de) |
| PL (1) | PL187914B1 (de) |
| PT (1) | PT893998E (de) |
| SK (1) | SK284539B6 (de) |
| WO (1) | WO1997028801A1 (de) |
| ZA (1) | ZA971020B (de) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5889028A (en) * | 1996-02-09 | 1999-03-30 | Mayo Foundation For Medical Education And Research | Colonic delivery of nicotine to treat inflammatory bowel disease |
| GB9614902D0 (en) | 1996-07-16 | 1996-09-04 | Rhodes John | Sustained release composition |
| US6268386B1 (en) * | 1998-06-25 | 2001-07-31 | Marshall Anlauf Thompson | Nicotine beverage |
| US6677319B1 (en) * | 1998-08-06 | 2004-01-13 | Wolfgang Stremmel | Phosphatidylcholine as medication with protective effect large intestinal mucosa |
| WO2000047195A1 (en) * | 1999-02-12 | 2000-08-17 | Washington University | Stimulating neutrophil function to treat inflammatory bowel disease |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| WO2001032180A2 (en) * | 1999-11-01 | 2001-05-10 | Rodeva Limited | Composition for treatment of constipation and irritable bowel syndrome |
| US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
| IT1318625B1 (it) | 2000-07-14 | 2003-08-27 | Roberto Valducci | Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente. |
| US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| CA2418135C (en) * | 2000-08-03 | 2011-09-20 | Antares Pharma Ipl Ag | Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels |
| US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
| CA2341952A1 (en) | 2001-03-23 | 2002-09-23 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory pulmonary diseases |
| US20050130990A1 (en) * | 2001-03-23 | 2005-06-16 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
| US20030108592A1 (en) * | 2001-12-10 | 2003-06-12 | Thompson Marshall Anlauf | Method of producing a nicotine composition |
| US20060204598A1 (en) * | 2001-12-10 | 2006-09-14 | Thompson Marshall A | Nicotine-alternative compositions and methods of producing such compositions |
| US20050131031A1 (en) * | 2001-12-10 | 2005-06-16 | Thompson Marshall A. | Method of producing a nicotine composition |
| US20100160376A1 (en) * | 2001-12-10 | 2010-06-24 | Marshall Anlauf Thompson | Nicotine-alternative compositions and methods of producing such compositions |
| US7091357B2 (en) | 2001-12-26 | 2006-08-15 | University Of Kentucky Research Foundation | Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies |
| US8557804B2 (en) | 2002-03-25 | 2013-10-15 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
| US8039459B2 (en) * | 2004-07-15 | 2011-10-18 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
| IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
| US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| AU2003279493B2 (en) | 2002-10-25 | 2009-08-20 | Foamix Pharmaceuticals Ltd. | Cosmetic and pharmaceutical foam |
| US8119109B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Foamable compositions, kits and methods for hyperhidrosis |
| US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
| US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US8119150B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
| US8084432B2 (en) * | 2003-02-13 | 2011-12-27 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of pouchitis |
| US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
| US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| EP1670433B1 (de) | 2003-10-10 | 2011-11-23 | Antares Pharma IPL AG | Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut |
| ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| AU2005284908B2 (en) | 2004-09-13 | 2011-12-08 | Morningside Venture Investments Limited | Biosynchronous transdermal drug delivery |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
| WO2006080919A1 (en) * | 2005-01-27 | 2006-08-03 | Marshall Anlauf Thompson | Method of producing a nicotine composition |
| WO2007124250A2 (en) | 2006-04-21 | 2007-11-01 | Antares Pharma Ipl Ag | Methods of treating hot flashes with formulations for transdermal or transmucosal application |
| US8067399B2 (en) | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
| US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| WO2008103818A1 (en) * | 2007-02-21 | 2008-08-28 | University Of Louisville Research Foundation | Therapeutic cotinine compositions |
| GB2468424B (en) * | 2007-04-02 | 2011-11-09 | Parkinson S Inst | Methods and compositions for reduction of side effects of therapeutic treatments |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
| WO2009090495A2 (en) | 2007-12-07 | 2009-07-23 | Foamix Ltd. | Oil and liquid silicone foamable carriers and formulations |
| EP2242476A2 (de) | 2008-01-14 | 2010-10-27 | Foamix Ltd. | Aufschäumbare pharmazeutische poloxamer-zusammensetzungen mit wirkstoffen und/oder therapeutischen zellen und verwendungen |
| EP2100599A1 (de) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung |
| EP2100598A1 (de) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung |
| WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| MX359879B (es) | 2009-10-02 | 2018-10-12 | Foamix Pharmaceuticals Ltd | Composiciones tópicas de tetraciclina. |
| EP2510928A1 (de) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten |
| EP2729148A4 (de) | 2011-07-06 | 2015-04-22 | Parkinson S Inst | Zusammensetzungen und verfahren zur behandlung von symptomen bei patienten mit morbus parkinson |
| BR112014030835B1 (pt) * | 2012-06-15 | 2022-01-11 | Conaris Research Institute Ag | Composição contendo ácido nicotínico e/ou nicotinamida e/ou triptofano, e uso da mesma |
| AU2014363430A1 (en) | 2013-12-13 | 2016-06-16 | Conaris Research Institute Ag | A pharmaceutical composition containing combinations of nicotinamide and 5-aminosalicylic acid for beneficially influencing the intestinal microbiota and/or treating gastrointestinal inflammation |
| WO2015086843A2 (en) | 2013-12-13 | 2015-06-18 | Conaris Research Institute Ag | A pharmaceutical composition containing nicotinic acid and/or nicotinamide for beneficially influencing blood lipid levels by modifying the intestinal microbiota |
| GB201400442D0 (en) * | 2014-01-10 | 2014-02-26 | Sigmoid Pharma Ltd | Compositions for use in the treatment of ulcerative colitis |
| JP2018511355A (ja) | 2015-01-28 | 2018-04-26 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 薬剤送達方法及びシステム |
| JP2018511127A (ja) | 2015-03-12 | 2018-04-19 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 渇望入力及び支援システム |
| CA2978573A1 (en) | 2016-09-08 | 2018-03-08 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| EP3565617A1 (de) | 2017-01-06 | 2019-11-13 | Chrono Therapeutics Inc. | Vorrichtungen und verfahren zur transdermalen wirkstofffreisetzung |
| AU2019279884B2 (en) | 2018-05-29 | 2025-01-30 | Morningside Venture Investments Limited | Drug delivery methods and systems |
| CA3119992A1 (en) | 2018-11-16 | 2020-05-22 | Morningside Venture Investments Limited | Thermally regulated transdermal drug delivery system |
| MX2022001865A (es) | 2019-08-12 | 2022-03-11 | Massachusetts Inst Technology | Articulos y metodos para la administracion de agentes terapeuticos. |
| CN115089641B (zh) * | 2022-05-25 | 2023-07-25 | 西安交通大学医学院第一附属医院 | 一种难治型溃疡性结肠炎灌肠剂及其制备方法 |
| WO2025236078A1 (en) * | 2024-05-09 | 2025-11-20 | Tjp Labs Inc. | Stabilized nicotine particles |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3639418A1 (de) * | 1986-11-18 | 1988-06-09 | Forschungsgesellschaft Rauchen | Nikotinhaltiges mittel |
| US4855142A (en) * | 1987-02-27 | 1989-08-08 | Ciba-Geigy Corporation | Pharmaceutical plaster |
| IE62662B1 (en) * | 1989-01-06 | 1995-02-22 | Elan Corp Plc | Use of nicotine in the treatment of conditions susceptible to said treatment |
| CA2087596A1 (en) * | 1990-07-20 | 1992-01-21 | John Rhodes | Products and processes for the treatment of the alimentary canal |
| GEP19971086B (en) * | 1991-02-22 | 1997-12-02 | Tillotts Pharma Ag | Peroral Pharmaceutically Dispensed Form for Selective Introducing of the Medicine into the Intestine |
| GB9310412D0 (en) * | 1993-05-20 | 1993-07-07 | Danbiosyst Uk | Nasal nicotine system |
| KR0121127B1 (ko) * | 1994-05-09 | 1997-11-13 | 강박광 | 이온성 고분자 네트웍을 갖는 피부약물전달체계 |
| US5604231A (en) * | 1995-01-06 | 1997-02-18 | Smith; Carr J. | Pharmaceutical compositions for prevention and treatment of ulcerative colitis |
| US5532254A (en) † | 1995-06-07 | 1996-07-02 | Eli Lilly And Company | Modulation of calcium channels using benzothiophenes |
| GB9614902D0 (en) * | 1996-07-16 | 1996-09-04 | Rhodes John | Sustained release composition |
-
1996
- 1996-02-09 US US08/605,319 patent/US5846983A/en not_active Expired - Fee Related
-
1997
- 1997-02-06 MY MYPI97000462A patent/MY122023A/en unknown
- 1997-02-07 WO PCT/GB1997/000369 patent/WO1997028801A1/en not_active Ceased
- 1997-02-07 ES ES97904516T patent/ES2196303T5/es not_active Expired - Lifetime
- 1997-02-07 DE DE69720985T patent/DE69720985T3/de not_active Expired - Fee Related
- 1997-02-07 AT AT97904516T patent/ATE237330T1/de not_active IP Right Cessation
- 1997-02-07 EP EP97904516A patent/EP0893998B2/de not_active Expired - Lifetime
- 1997-02-07 SK SK1068-98A patent/SK284539B6/sk unknown
- 1997-02-07 PT PT97904516T patent/PT893998E/pt unknown
- 1997-02-07 HU HU9900950A patent/HUP9900950A3/hu unknown
- 1997-02-07 PL PL32843097A patent/PL187914B1/pl not_active IP Right Cessation
- 1997-02-07 CZ CZ19982451A patent/CZ293616B6/cs not_active IP Right Cessation
- 1997-02-07 CN CN97192177A patent/CN1127340C/zh not_active Expired - Fee Related
- 1997-02-07 DK DK97904516T patent/DK0893998T4/da active
- 1997-02-07 JP JP52830797A patent/JP4283340B2/ja not_active Expired - Fee Related
- 1997-02-07 KR KR10-1998-0706162A patent/KR100458636B1/ko not_active Expired - Fee Related
- 1997-02-07 CA CA002246235A patent/CA2246235C/en not_active Expired - Fee Related
- 1997-02-07 AU AU17294/97A patent/AU718971C/en not_active Ceased
- 1997-02-07 ZA ZA9701020A patent/ZA971020B/xx unknown
-
1998
- 1998-08-06 MX MX9806354A patent/MX9806354A/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE237330T1 (de) | Verabreichung von nikotin im dickdarm zur behandlung von entzündlicher eingeweidenerkrankung | |
| ATE375341T1 (de) | Thiadiazolylpiperazinderivate geeignet für die behandlung bzw. prävention von schmerzen | |
| NO20031019D0 (no) | Vedvarende frigivelsesformuleringer av oksymorfon | |
| DE69613840D1 (de) | Orale dosierungsform und verfahren zur behandlung von schmerzzuständen in dermundhöhle | |
| IS1907B (is) | Notkun klóbindiefnisins klíókínól við að framleiða lyfjablöndu til að meðhöndla Alzheimers-sjúkdóm | |
| ATE355374T1 (de) | Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen | |
| CY1105120T1 (el) | Η αντιμετωπιση αναπνευστικων νοσων | |
| BR0114799A (pt) | Compostos de ácido cianofenoxi carboxìlico e composições para liberar agentes ativos | |
| SE0002754D0 (sv) | New pharmaceutical combination formulation and method of treatment with the combination | |
| DK0998287T3 (da) | Anvendelse af levobupivacain | |
| SE9900961D0 (sv) | Novel compounds | |
| NZ507203A (en) | Use of dexmedetomidine for ICU sedation | |
| DE69424777D1 (de) | 3,4-diarylchromane zur behandlung von dermatitis | |
| ATE205704T1 (de) | 5-asa enthaltendes orales arzneimittel mit modifizierter freisetzung sowie verfahren zur behandlung von darmerkrankungen | |
| ATE366107T1 (de) | Verwendung von sulfodehydroabietinsäure zur behandlung entzündlicher darmerkrankungen | |
| DK0856312T3 (da) | Anvendelse af trospiumchlorid til fremstilling af et lægemiddel til behandling af blæresygdomme | |
| DK1294379T3 (da) | En hidtil ukendt anvendelse af deferipron | |
| DE60026491D1 (de) | Melagatran zur behandlung von entzündungen | |
| FR2794977B1 (fr) | Utilisation de compositions contenant des formes solubles d'hla-g dans le traitement de pathologies inflammatoires de la peau, et leur procede d'obtention | |
| CA2077693A1 (en) | Use of ketorolac for treatment of periodontal disease | |
| DE60130253D1 (de) | Zusammensetzungen zur verhinderung der adhäsion | |
| ATE190845T1 (de) | Rektale flunisolid-zubereitung zur behandlung entzündlicher darmerkrankungen | |
| MY133957A (en) | "compounds useful for the treatment or prevention of a disease mediated by the alpha-2b-adrenoceptor" | |
| DE60003921D1 (de) | Diphenyl-1,2,3-thiadiazol-3-oxide, zusammensetzungen und verfahren zur anwendung | |
| UA49889C2 (uk) | Антибактеріальний препарат "бороцин" |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0893998 Country of ref document: EP |
|
| UEP | Publication of translation of european patent specification |
Ref document number: 0893998 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |