ATE237621T1 - Herstellung von einem kristallinen amoxicillinsalz - Google Patents
Herstellung von einem kristallinen amoxicillinsalzInfo
- Publication number
- ATE237621T1 ATE237621T1 AT96937268T AT96937268T ATE237621T1 AT E237621 T1 ATE237621 T1 AT E237621T1 AT 96937268 T AT96937268 T AT 96937268T AT 96937268 T AT96937268 T AT 96937268T AT E237621 T1 ATE237621 T1 AT E237621T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- pct
- salt
- crystalline amoxicillin
- date
- Prior art date
Links
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical class C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 title abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 229960003022 amoxicillin Drugs 0.000 abstract 2
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9521921.8A GB9521921D0 (en) | 1995-10-26 | 1995-10-26 | Organic compounds |
| GBGB9611088.7A GB9611088D0 (en) | 1996-05-28 | 1996-05-28 | Organic compounds |
| PCT/EP1996/004682 WO1997015579A1 (en) | 1995-10-26 | 1996-10-28 | Production of a crystalline salt of amoxicillin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237621T1 true ATE237621T1 (de) | 2003-05-15 |
Family
ID=26308006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96937268T ATE237621T1 (de) | 1995-10-26 | 1996-10-28 | Herstellung von einem kristallinen amoxicillinsalz |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6103897A (de) |
| EP (1) | EP0871632B1 (de) |
| JP (1) | JP4104166B2 (de) |
| AT (1) | ATE237621T1 (de) |
| AU (1) | AU7494496A (de) |
| DE (1) | DE69627533T2 (de) |
| DK (1) | DK0871632T3 (de) |
| ES (1) | ES2197253T3 (de) |
| PT (1) | PT871632E (de) |
| TW (1) | TW347383B (de) |
| WO (1) | WO1997015579A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU760934B2 (en) * | 1998-06-01 | 2003-05-22 | Smithkline Beecham Corporation | Process for preparing crystalline salts of amoxycillin |
| US6211384B1 (en) | 1999-08-30 | 2001-04-03 | Novartis Pharmaceuticals Corp. | Methods for the acylation of amine compounds |
| AT412213B (de) * | 2000-05-30 | 2004-11-25 | Sandoz Ag | Verfahren zur trocknung von amoxicillin oder amoxicillin-hältigen, oralen, festen pharmazeutischen zusammensetzungen unter verwendung eines gases mit einer definierten gasfeuchte |
| CN101633663B (zh) * | 2009-08-28 | 2011-12-21 | 沈阳顺旺动物药业有限公司 | 一种青霉素类钠、钾盐的合成方法 |
| CN102838620B (zh) * | 2012-09-05 | 2014-07-30 | 河北科技大学 | 一种阿莫西林钠结晶的制备工艺 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1286199A (en) * | 1970-03-16 | 1972-08-23 | Beecham Group Ltd | Penicillins |
| US3932386A (en) * | 1973-06-18 | 1976-01-13 | American Home Products Corporation | Sodium 6-(L-aminocyclohexane carboxamido)penicillanic acid |
| GB1464026A (en) * | 1974-09-25 | 1977-02-09 | Beecham Group Ltd | Preparation of beta-lactam antibiotics |
| GB1463563A (en) * | 1974-10-10 | 1977-02-02 | Beecham Group Ltd | Pharmaceutical compositions |
| DE3474023D1 (en) * | 1983-06-10 | 1988-10-20 | Beecham Group Plc | Crystalline amoxycillin salt |
| DE3431273A1 (de) * | 1984-08-25 | 1986-03-06 | Bayer Ag, 5090 Leverkusen | Kristallines natriumsalz der d-6-((alpha)-(2-oxo-3-furfuryl-iden-amino-imidazolidin-1-yl)-carbonylamino)-thienyl-2-acetamido)-penicillansaeure, verfahren zur herstellung und seine verwendung in arzneimitteln |
| ES8606871A1 (es) * | 1985-10-21 | 1986-06-01 | Antibioticos Sa | Un procedimiento de preparacion de amoxicilina sodica |
| IT1255716B (it) * | 1992-10-05 | 1995-11-10 | Procedimento per la preparazione di antibiotici beta-lattamici sterili |
-
1996
- 1996-10-23 TW TW085112977A patent/TW347383B/zh not_active IP Right Cessation
- 1996-10-28 PT PT96937268T patent/PT871632E/pt unknown
- 1996-10-28 US US09/066,476 patent/US6103897A/en not_active Expired - Lifetime
- 1996-10-28 AT AT96937268T patent/ATE237621T1/de active
- 1996-10-28 EP EP96937268A patent/EP0871632B1/de not_active Expired - Lifetime
- 1996-10-28 DK DK96937268T patent/DK0871632T3/da active
- 1996-10-28 DE DE69627533T patent/DE69627533T2/de not_active Expired - Lifetime
- 1996-10-28 JP JP51630197A patent/JP4104166B2/ja not_active Expired - Lifetime
- 1996-10-28 AU AU74944/96A patent/AU7494496A/en not_active Abandoned
- 1996-10-28 WO PCT/EP1996/004682 patent/WO1997015579A1/en not_active Ceased
- 1996-10-28 ES ES96937268T patent/ES2197253T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4104166B2 (ja) | 2008-06-18 |
| DK0871632T3 (da) | 2003-07-28 |
| JPH11515011A (ja) | 1999-12-21 |
| ES2197253T3 (es) | 2004-01-01 |
| AU7494496A (en) | 1997-05-15 |
| DE69627533D1 (de) | 2003-05-22 |
| US6103897A (en) | 2000-08-15 |
| WO1997015579A1 (en) | 1997-05-01 |
| DE69627533T2 (de) | 2003-12-18 |
| PT871632E (pt) | 2003-08-29 |
| EP0871632B1 (de) | 2003-04-16 |
| EP0871632A1 (de) | 1998-10-21 |
| TW347383B (en) | 1998-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEFA | Change of the company name | ||
| UEP | Publication of translation of european patent specification |
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