ATE237637T1 - Somatostatin derivate und deren radiomarkierte produkte - Google Patents

Somatostatin derivate und deren radiomarkierte produkte

Info

Publication number: ATE237637T1
Authority: AT; Austria
Prior art keywords: peptides; somatostatin; radiolabeled; radiodiagnostic; methods
Prior art date: 1993-07-21

Application number

AT94925686T

Other languages

English (en)

Inventor

William Mcbride

Richard T Dean

Original Assignee

Diatide Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-21

Filing date

1994-07-21

Publication date

2003-05-15

1994-07-21 Application filed by Diatide Inc filed Critical Diatide Inc

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE237637T1 publication Critical patent/ATE237637T1/de

Links

NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 4
108090000765 processed proteins & peptides Proteins 0.000 abstract 8
102000004196 processed proteins & peptides Human genes 0.000 abstract 5
238000000034 method Methods 0.000 abstract 3
WUAPFZMCVAUBPE-NJFSPNSNSA-N 188Re Chemical compound [188Re] WUAPFZMCVAUBPE-NJFSPNSNSA-N 0.000 abstract 2
239000003153 chemical reaction reagent Substances 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 2
238000000163 radioactive labelling Methods 0.000 abstract 2
230000003439 radiotherapeutic effect Effects 0.000 abstract 2
WUAPFZMCVAUBPE-IGMARMGPSA-N rhenium-186 Chemical compound [186Re] WUAPFZMCVAUBPE-IGMARMGPSA-N 0.000 abstract 2
102000005157 Somatostatin Human genes 0.000 abstract 1
108010056088 Somatostatin Proteins 0.000 abstract 1
GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 abstract 1
231100000433 cytotoxic Toxicity 0.000 abstract 1
230000001472 cytotoxic effect Effects 0.000 abstract 1
239000012216 imaging agent Substances 0.000 abstract 1
229960000553 somatostatin Drugs 0.000 abstract 1
229940056501 technetium 99m Drugs 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Optics & Photonics (AREA)
Public Health (AREA)
Physics & Mathematics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT94925686T 1993-07-21 1994-07-21 Somatostatin derivate und deren radiomarkierte produkte ATE237637T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/095,760 US5620675A (en)	1992-06-23	1993-07-21	Radioactive peptides
PCT/US1994/008335 WO1995003330A1 (en)	1993-07-21	1994-07-21	Somatostatin derivatives and their radiolabelled products

Publications (1)

Publication Number	Publication Date
ATE237637T1 true ATE237637T1 (de)	2003-05-15

Family

ID=22253472

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94925686T ATE237637T1 (de)	1993-07-21	1994-07-21	Somatostatin derivate und deren radiomarkierte produkte

Country Status (11)

Country	Link
US (2)	US5620675A (de)
EP (1)	EP0804481B1 (de)
JP (1)	JP3601827B2 (de)
AT (1)	ATE237637T1 (de)
AU (1)	AU684823B2 (de)
CA (1)	CA2167678C (de)
DE (1)	DE69432530T2 (de)
DK (1)	DK0804481T3 (de)
ES (1)	ES2197169T3 (de)
WO (1)	WO1995003330A1 (de)
ZA (1)	ZA945367B (de)

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1993
- 1993-07-21 US US08/095,760 patent/US5620675A/en not_active Expired - Fee Related
1994
- 1994-07-21 CA CA002167678A patent/CA2167678C/en not_active Expired - Fee Related
- 1994-07-21 US US08/586,670 patent/US6241965B1/en not_active Expired - Fee Related
- 1994-07-21 AU AU75506/94A patent/AU684823B2/en not_active Ceased
- 1994-07-21 DE DE69432530T patent/DE69432530T2/de not_active Expired - Fee Related
- 1994-07-21 ZA ZA945367A patent/ZA945367B/xx unknown
- 1994-07-21 AT AT94925686T patent/ATE237637T1/de not_active IP Right Cessation
- 1994-07-21 DK DK94925686T patent/DK0804481T3/da active
- 1994-07-21 WO PCT/US1994/008335 patent/WO1995003330A1/en not_active Ceased
- 1994-07-21 ES ES94925686T patent/ES2197169T3/es not_active Expired - Lifetime
- 1994-07-21 JP JP50535995A patent/JP3601827B2/ja not_active Expired - Fee Related
- 1994-07-21 EP EP94925686A patent/EP0804481B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2167678C (en)	2002-07-02
AU7550694A (en)	1995-02-20
ES2197169T3 (es)	2004-01-01
DK0804481T3 (da)	2003-07-28
AU684823B2 (en)	1998-01-08
CA2167678A1 (en)	1995-02-02
EP0804481B1 (de)	2003-04-16
JPH09501419A (ja)	1997-02-10
ZA945367B (en)	1995-04-05
WO1995003330A1 (en)	1995-02-02
EP0804481A1 (de)	1997-11-05
US5620675A (en)	1997-04-15
US6241965B1 (en)	2001-06-05
JP3601827B2 (ja)	2004-12-15
DE69432530T2 (de)	2004-04-08
DE69432530D1 (de)	2003-05-22

Legal Events

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2003-12-15

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Publication	Publication Date	Title
DE69432530D1 (de)	2003-05-22	Somatostatin derivate und deren radiomarkierte produkte
AU3415197A (en)	1997-11-06	Technetium-99m labelled peptides for imaging
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