ATE238985T1 - Hydroxamsäure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungen - Google Patents

Hydroxamsäure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungen

Info

Publication number: ATE238985T1
Authority: AT; Austria
Prior art keywords: alkyl; cycloalkyl; aryl; optionally substituted; heterocyclic
Prior art date: 1998-08-10

Application number

AT99402016T

Other languages

English (en)

Inventor

Stephen Hanessian

Ghanem Atassi

Gordon Tucker

Daniel-Henri Caignard

Pierre Renard

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-10

Filing date

1999-08-09

Publication date

2003-05-15

1999-08-09 Application filed by Servier Lab filed Critical Servier Lab

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE238985T1 publication Critical patent/ATE238985T1/de

Links

239000002253 acid Substances 0.000 title abstract 4
NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title abstract 3
239000008194 pharmaceutical composition Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 10
125000003118 aryl group Chemical group 0.000 abstract 8
125000000623 heterocyclic group Chemical group 0.000 abstract 7
125000000753 cycloalkyl group Chemical group 0.000 abstract 6
125000002252 acyl group Chemical group 0.000 abstract 3
125000002947 alkylene group Chemical group 0.000 abstract 3
125000003710 aryl alkyl group Chemical group 0.000 abstract 3
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000004457 alkyl amino carbonyl group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000004103 aminoalkyl group Chemical group 0.000 abstract 1
125000005097 aminocarbonylalkyl group Chemical group 0.000 abstract 1
125000000732 arylene group Chemical group 0.000 abstract 1
125000005841 biaryl group Chemical group 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000005549 heteroarylene group Chemical group 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
125000005358 mercaptoalkyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000003396 thiol group Chemical class [H]S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Pyrane Compounds (AREA)

AT99402016T 1998-08-10 1999-08-09 Hydroxamsäure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungen ATE238985T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9810237A FR2782080B1 (fr)	1998-08-10	1998-08-10	Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
ATE238985T1 true ATE238985T1 (de)	2003-05-15

Family

ID=9529555

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99402016T ATE238985T1 (de)	1998-08-10	1999-08-09	Hydroxamsäure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungen

Country Status (18)

Country	Link
US (1)	US6063816A (de)
EP (1)	EP0979816B1 (de)
JP (1)	JP2000086618A (de)
CN (1)	CN1166632C (de)
AT (1)	ATE238985T1 (de)
AU (1)	AU750691B2 (de)
BR (1)	BR9903568A (de)
CA (1)	CA2280395C (de)
DE (1)	DE69907337T2 (de)
DK (1)	DK0979816T3 (de)
ES (1)	ES2198863T3 (de)
FR (1)	FR2782080B1 (de)
HU (1)	HUP9902700A3 (de)
NO (1)	NO313516B1 (de)
NZ (1)	NZ337142A (de)
PL (1)	PL334831A1 (de)
PT (1)	PT979816E (de)
ZA (1)	ZA995091B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2245876C2 (ru)	2000-03-21	2005-02-10	Дзе Проктер Энд Гэмбл Компани	Производные сульфонамидов и фармацевтическая композиция на их основе
CA2401728A1 (en)	2000-03-21	2001-09-27	The Procter & Gamble Company	Difluorobutyric acid metalloprotease inhibitors
FR2819252A1 (fr) *	2001-01-11	2002-07-12	Servier Lab	Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2819253B1 (fr) *	2001-01-11	2004-12-03	Servier Lab	Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN108672095A (zh) *	2018-05-04	2018-10-19	广东省资源综合利用研究所	γ-羟基烷基羟肟酸及其制备方法与应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5552419A (en) *	1993-01-06	1996-09-03	Ciba-Geigy Corporation	Arylsulfonamido-substituted hydroxamic acids
US5506242A (en) *	1993-01-06	1996-04-09	Ciba-Geigy Corporation	Arylsufonamido-substituted hydroxamic acids
US5455258A (en) *	1993-01-06	1995-10-03	Ciba-Geigy Corporation	Arylsulfonamido-substituted hydroxamic acids
US5646167A (en) *	1993-01-06	1997-07-08	Ciba-Geigy Corporation	Arylsulfonamido-substituted hydroxamix acids
US5817822A (en) *	1994-06-24	1998-10-06	Novartis Corporation	Certain alpha-azacycloalkyl substituted arylsulfonamido acetohydroxamic acids

1998
- 1998-08-10 FR FR9810237A patent/FR2782080B1/fr not_active Expired - Fee Related
1999
- 1999-08-09 ES ES99402016T patent/ES2198863T3/es not_active Expired - Lifetime
- 1999-08-09 DK DK99402016T patent/DK0979816T3/da active
- 1999-08-09 BR BR9903568-5A patent/BR9903568A/pt not_active IP Right Cessation
- 1999-08-09 DE DE69907337T patent/DE69907337T2/de not_active Expired - Fee Related
- 1999-08-09 EP EP99402016A patent/EP0979816B1/de not_active Expired - Lifetime
- 1999-08-09 JP JP11225599A patent/JP2000086618A/ja active Pending
- 1999-08-09 NO NO19993829A patent/NO313516B1/no unknown
- 1999-08-09 CA CA002280395A patent/CA2280395C/fr not_active Expired - Fee Related
- 1999-08-09 PL PL99334831A patent/PL334831A1/xx not_active Application Discontinuation
- 1999-08-09 NZ NZ337142A patent/NZ337142A/xx unknown
- 1999-08-09 PT PT99402016T patent/PT979816E/pt unknown
- 1999-08-09 HU HU9902700A patent/HUP9902700A3/hu unknown
- 1999-08-09 US US09/370,712 patent/US6063816A/en not_active Expired - Fee Related
- 1999-08-09 AT AT99402016T patent/ATE238985T1/de not_active IP Right Cessation
- 1999-08-10 AU AU43466/99A patent/AU750691B2/en not_active Ceased
- 1999-08-10 ZA ZA9905091A patent/ZA995091B/xx unknown
- 1999-08-10 CN CNB991175190A patent/CN1166632C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2280395A1 (fr)	2000-02-10
HUP9902700A2 (hu)	2000-05-28
DE69907337D1 (de)	2003-06-05
ZA995091B (en)	2000-02-10
NO993829D0 (no)	1999-08-09
US6063816A (en)	2000-05-16
BR9903568A (pt)	2000-09-19
JP2000086618A (ja)	2000-03-28
PL334831A1 (en)	2000-02-14
HU9902700D0 (en)	1999-10-28
DE69907337T2 (de)	2004-02-26
PT979816E (pt)	2003-08-29
FR2782080B1 (fr)	2001-01-05
NO993829L (no)	2000-02-11
AU4346699A (en)	2000-03-02
FR2782080A1 (fr)	2000-02-11
CN1166632C (zh)	2004-09-15
CN1245798A (zh)	2000-03-01
AU750691B2 (en)	2002-07-25
NZ337142A (en)	2000-10-27
EP0979816B1 (de)	2003-05-02
ES2198863T3 (es)	2004-02-01
DK0979816T3 (da)	2003-08-25
NO313516B1 (no)	2002-10-14
EP0979816A1 (de)	2000-02-16
HUP9902700A3 (en)	2002-03-28
CA2280395C (fr)	2003-07-08

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2003-11-15

UEP

Publication of translation of european patent specification

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Country of ref document: EP

2006-05-15

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Ceased due to non-payment of the annual fee