ATE238985T1 - Hydroxamsäure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungen - Google Patents
Hydroxamsäure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungenInfo
- Publication number
- ATE238985T1 ATE238985T1 AT99402016T AT99402016T ATE238985T1 AT E238985 T1 ATE238985 T1 AT E238985T1 AT 99402016 T AT99402016 T AT 99402016T AT 99402016 T AT99402016 T AT 99402016T AT E238985 T1 ATE238985 T1 AT E238985T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- cycloalkyl
- aryl
- optionally substituted
- heterocyclic
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 4
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 10
- 125000003118 aryl group Chemical group 0.000 abstract 8
- 125000000623 heterocyclic group Chemical group 0.000 abstract 7
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 6
- 125000002252 acyl group Chemical group 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 125000005097 aminocarbonylalkyl group Chemical group 0.000 abstract 1
- 125000000732 arylene group Chemical group 0.000 abstract 1
- 125000005841 biaryl group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000005549 heteroarylene group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000005358 mercaptoalkyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003396 thiol group Chemical class [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9810237A FR2782080B1 (fr) | 1998-08-10 | 1998-08-10 | Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE238985T1 true ATE238985T1 (de) | 2003-05-15 |
Family
ID=9529555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99402016T ATE238985T1 (de) | 1998-08-10 | 1999-08-09 | Hydroxamsäure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungen |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6063816A (de) |
| EP (1) | EP0979816B1 (de) |
| JP (1) | JP2000086618A (de) |
| CN (1) | CN1166632C (de) |
| AT (1) | ATE238985T1 (de) |
| AU (1) | AU750691B2 (de) |
| BR (1) | BR9903568A (de) |
| CA (1) | CA2280395C (de) |
| DE (1) | DE69907337T2 (de) |
| DK (1) | DK0979816T3 (de) |
| ES (1) | ES2198863T3 (de) |
| FR (1) | FR2782080B1 (de) |
| HU (1) | HUP9902700A3 (de) |
| NO (1) | NO313516B1 (de) |
| NZ (1) | NZ337142A (de) |
| PL (1) | PL334831A1 (de) |
| PT (1) | PT979816E (de) |
| ZA (1) | ZA995091B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1265864A1 (de) | 2000-03-21 | 2002-12-18 | The Procter & Gamble Company | Heterozyklische seitenkette enhaltende, n-substituierte metalloproteaseinhibitoren |
| JP2003528082A (ja) | 2000-03-21 | 2003-09-24 | ザ プロクター アンド ギャンブル カンパニー | ニフッ化酪酸メタロプロテアーゼ阻害物質 |
| FR2819252A1 (fr) * | 2001-01-11 | 2002-07-12 | Servier Lab | Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2819253B1 (fr) * | 2001-01-11 | 2004-12-03 | Servier Lab | Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CN108672095A (zh) * | 2018-05-04 | 2018-10-19 | 广东省资源综合利用研究所 | γ-羟基烷基羟肟酸及其制备方法与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5552419A (en) * | 1993-01-06 | 1996-09-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| US5646167A (en) * | 1993-01-06 | 1997-07-08 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamix acids |
| US5506242A (en) * | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
| US5817822A (en) * | 1994-06-24 | 1998-10-06 | Novartis Corporation | Certain alpha-azacycloalkyl substituted arylsulfonamido acetohydroxamic acids |
-
1998
- 1998-08-10 FR FR9810237A patent/FR2782080B1/fr not_active Expired - Fee Related
-
1999
- 1999-08-09 JP JP11225599A patent/JP2000086618A/ja active Pending
- 1999-08-09 US US09/370,712 patent/US6063816A/en not_active Expired - Fee Related
- 1999-08-09 PT PT99402016T patent/PT979816E/pt unknown
- 1999-08-09 AT AT99402016T patent/ATE238985T1/de not_active IP Right Cessation
- 1999-08-09 DK DK99402016T patent/DK0979816T3/da active
- 1999-08-09 EP EP99402016A patent/EP0979816B1/de not_active Expired - Lifetime
- 1999-08-09 HU HU9902700A patent/HUP9902700A3/hu unknown
- 1999-08-09 ES ES99402016T patent/ES2198863T3/es not_active Expired - Lifetime
- 1999-08-09 NO NO19993829A patent/NO313516B1/no unknown
- 1999-08-09 DE DE69907337T patent/DE69907337T2/de not_active Expired - Fee Related
- 1999-08-09 BR BR9903568-5A patent/BR9903568A/pt not_active IP Right Cessation
- 1999-08-09 CA CA002280395A patent/CA2280395C/fr not_active Expired - Fee Related
- 1999-08-09 NZ NZ337142A patent/NZ337142A/xx unknown
- 1999-08-09 PL PL99334831A patent/PL334831A1/xx not_active Application Discontinuation
- 1999-08-10 AU AU43466/99A patent/AU750691B2/en not_active Ceased
- 1999-08-10 CN CNB991175190A patent/CN1166632C/zh not_active Expired - Fee Related
- 1999-08-10 ZA ZA9905091A patent/ZA995091B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO993829D0 (no) | 1999-08-09 |
| DK0979816T3 (da) | 2003-08-25 |
| EP0979816A1 (de) | 2000-02-16 |
| CN1166632C (zh) | 2004-09-15 |
| BR9903568A (pt) | 2000-09-19 |
| ZA995091B (en) | 2000-02-10 |
| HUP9902700A2 (hu) | 2000-05-28 |
| PT979816E (pt) | 2003-08-29 |
| NO313516B1 (no) | 2002-10-14 |
| US6063816A (en) | 2000-05-16 |
| FR2782080B1 (fr) | 2001-01-05 |
| HU9902700D0 (en) | 1999-10-28 |
| CN1245798A (zh) | 2000-03-01 |
| CA2280395A1 (fr) | 2000-02-10 |
| AU750691B2 (en) | 2002-07-25 |
| AU4346699A (en) | 2000-03-02 |
| EP0979816B1 (de) | 2003-05-02 |
| ES2198863T3 (es) | 2004-02-01 |
| PL334831A1 (en) | 2000-02-14 |
| HUP9902700A3 (en) | 2002-03-28 |
| DE69907337T2 (de) | 2004-02-26 |
| DE69907337D1 (de) | 2003-06-05 |
| NO993829L (no) | 2000-02-11 |
| JP2000086618A (ja) | 2000-03-28 |
| FR2782080A1 (fr) | 2000-02-11 |
| CA2280395C (fr) | 2003-07-08 |
| NZ337142A (en) | 2000-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0979816 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |