ATE239042T1 - Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert ist - Google Patents
Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert istInfo
- Publication number
- ATE239042T1 ATE239042T1 AT97947624T AT97947624T ATE239042T1 AT E239042 T1 ATE239042 T1 AT E239042T1 AT 97947624 T AT97947624 T AT 97947624T AT 97947624 T AT97947624 T AT 97947624T AT E239042 T1 ATE239042 T1 AT E239042T1
- Authority
- AT
- Austria
- Prior art keywords
- water soluble
- arabinogalactan
- arabinogalactans
- lipidated
- derivatized
- Prior art date
Links
- 229920000189 Arabinogalactan Polymers 0.000 title abstract 8
- 235000019312 arabinogalactan Nutrition 0.000 title abstract 8
- SATHPVQTSSUFFW-UHFFFAOYSA-N 4-[6-[(3,5-dihydroxy-4-methoxyoxan-2-yl)oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-2-(hydroxymethyl)-6-methyloxane-3,5-diol Chemical compound OC1C(OC)C(O)COC1OCC1C(O)C(OC)C(O)C(OC2C(C(CO)OC(C)C2O)O)O1 SATHPVQTSSUFFW-UHFFFAOYSA-N 0.000 title abstract 4
- 239000001904 Arabinogalactan Substances 0.000 title abstract 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000021164 cell adhesion Effects 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/754,225 US6303584B1 (en) | 1996-11-20 | 1996-11-20 | Water soluble lipidated arabinogalactan |
| PCT/US1997/021497 WO1998022512A1 (en) | 1996-11-20 | 1997-11-20 | Water soluble lipidated arabinogalactan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239042T1 true ATE239042T1 (de) | 2003-05-15 |
Family
ID=25033934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97947624T ATE239042T1 (de) | 1996-11-20 | 1997-11-20 | Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert ist |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6303584B1 (de) |
| EP (1) | EP0939771B1 (de) |
| AT (1) | ATE239042T1 (de) |
| AU (1) | AU736535B2 (de) |
| CA (1) | CA2272362A1 (de) |
| DE (1) | DE69721557D1 (de) |
| WO (1) | WO1998022512A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6929807B1 (en) * | 1996-08-09 | 2005-08-16 | Mannatech, Inc. | Compositions of plant carbohydrates as dietary supplements |
| CA2330318A1 (en) * | 1998-04-27 | 1999-11-04 | Larex, Inc. | Derivatives of arabinogalactan and compositions including the same |
| US6703056B2 (en) | 2000-09-29 | 2004-03-09 | The Procter + Gamble Co. | Beverage compositions comprising arabinogalactan and defined minerals |
| US6706295B2 (en) | 2000-09-29 | 2004-03-16 | The Procter & Gamble Co. | Compositions comprising arabinogalactan and a defined protein component |
| US6455512B1 (en) * | 2001-03-05 | 2002-09-24 | Tic Gums, Inc. | Water-soluble esterified hydrocolloids |
| US7266151B2 (en) | 2002-09-04 | 2007-09-04 | Intel Corporation | Method and system for performing motion estimation using logarithmic search |
| US20050158329A1 (en) * | 2004-01-21 | 2005-07-21 | Ghosh Swapan K. | Novel phytol derived immunoadjuvants and their use in vaccine formulations |
| WO2007079448A2 (en) * | 2006-01-03 | 2007-07-12 | University Of Georgia Research Foundation, Inc. | Three component carbohydrate vaccine |
| CA2747569A1 (en) | 2007-12-21 | 2009-07-02 | University Of Graz | Use larch wood material for treating inflammation |
| NZ590010A (en) * | 2008-06-25 | 2013-01-25 | Braasch Biotech Llc | Compositions and methods treating growth hormone deficiency and/or an insulin-like growth factor 1 deficiency with somatostatin and an adjuvant |
| US20120039984A1 (en) | 2008-07-03 | 2012-02-16 | University Of Georgia Research Foundation, Inc. | Glycopeptide and uses thereof |
| FR2938192B1 (fr) | 2008-11-07 | 2012-08-24 | Expanscience Lab | Nouvel actif anti-vergetures et compositions le comprenant |
| EP2327411A1 (de) * | 2009-11-27 | 2011-06-01 | Lonza Ltd. | Arabinogalactan als Immunverstärker |
| US8784844B2 (en) | 2009-09-30 | 2014-07-22 | Lonza Ltd. | Arabinogalactan for enhancing the adaptive immune response |
| WO2011139168A1 (en) * | 2010-05-05 | 2011-11-10 | Comvita New Zealand Limited | Immunostimulatory compositions and methods of use thereof |
| US9393259B2 (en) | 2013-03-21 | 2016-07-19 | Lonza Ltd. | Composition comprising arabinogalactan and polyphenols from larch trees |
| US10994013B2 (en) | 2013-04-24 | 2021-05-04 | Temple University—Of the Commonwealth System of Higher Education | Solid dosage form containing arabinogalactan |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58190365A (ja) | 1982-04-30 | 1983-11-07 | Ajinomoto Co Inc | 冷凍フライ様食品の製造法 |
| US5106616A (en) | 1988-01-14 | 1992-04-21 | Carrington Laboratories, Inc. | Administration of acemannan |
| US4735935A (en) | 1985-12-17 | 1988-04-05 | Carrington Laboratories, Inc. | Process for preparation of aloe products products, produced thereby and compositions thereof |
| US5118673A (en) | 1982-05-07 | 1992-06-02 | Carrington Laboratories, Inc. | Uses of aloe products |
| US4966892A (en) | 1982-05-07 | 1990-10-30 | Carrington Laboratories, Inc. | Processes for preparation of aloe products products produced thereby and compositions thereof |
| US4851224A (en) | 1986-06-05 | 1989-07-25 | Carrington Laboratories, Inc. | Process for preparation of aloe products |
| US4917890A (en) | 1985-06-28 | 1990-04-17 | Carrington Laboratories, Inc. | Processes for preparation of aloe products, products produced thereby and compositions thereof |
| US5308838A (en) | 1982-05-07 | 1994-05-03 | Carrington Laboratories, Inc. | Uses of aloe products |
| US5443830A (en) | 1982-05-07 | 1995-08-22 | Carrington Laboratories, Inc. | Drink containing mucilaginous polysaccharides and its preparation |
| SE456911B (sv) | 1983-12-19 | 1988-11-14 | Olle Larm | Vattenloeslig, aminerad beta-1,3-bunden d-glukan och makrofagstimulerande komposition innehaallande densamma |
| JPS60233560A (ja) | 1984-05-02 | 1985-11-20 | Fujirebio Inc | リパ−ゼ活性の測定方法 |
| US4959214A (en) | 1985-06-28 | 1990-09-25 | Carrington Laboratories Inc. | Processes for preparation of aloe products products produced thereby and compositions thereof |
| US4957907A (en) | 1985-06-28 | 1990-09-18 | Carrington Laboratories Inc. | Process for preparation of aloe products |
| US4877611A (en) | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
| US5554386A (en) | 1986-07-03 | 1996-09-10 | Advanced Magnetics, Inc. | Delivery of therapeutic agents to receptors using polysaccharides |
| JPH0678363B2 (ja) | 1987-08-24 | 1994-10-05 | 財団法人杉山産業化学研究所 | 水溶性澱粉脂肪酸エステルの製造方法 |
| US5116969B1 (en) | 1990-04-26 | 1997-04-01 | Larex International Inc | Ultrarefined arabinogalactan product |
| JPH06508835A (ja) | 1991-06-24 | 1994-10-06 | キャリングタン、ラバラトーリズ、インコーパレイティド | 外傷清浄剤 |
| GB2260333A (en) | 1991-10-11 | 1993-04-14 | John Mark Lawther | Wax-like polysaccharide derivatives |
| WO1993008810A1 (en) | 1991-11-05 | 1993-05-13 | Carrington Laboratories, Inc. | Uses of aloe products, e.g. acemannan, in the treatment of diseases requiring intervention of the immune system for cure |
| DE4136325A1 (de) | 1991-11-05 | 1993-05-13 | Hoechst Ag | Cyclodextrinderivate als adsorptionsmittel fuer gallensaeure, mit gallensaeuren beladene cyclodextrinderivate und verfahren zu deren herstellung sowie deren anwendung als arzneimittel |
| EP0646018A1 (de) | 1992-06-17 | 1995-04-05 | Advanced Magnetics Incorporated | Arabinogalactan derivate und ihre anwendungen |
| US5409703A (en) | 1993-06-24 | 1995-04-25 | Carrington Laboratories, Inc. | Dried hydrogel from hydrophilic-hygroscopic polymer |
| WO1995012620A1 (en) | 1993-11-01 | 1995-05-11 | Alpha-Beta Technology, Inc. | Derivatized polysaccharide bile acid sequestrant for reducing cholesterol |
| EP0783508A1 (de) | 1994-09-20 | 1997-07-16 | PHARMACIA & UPJOHN COMPANY | Oligosaccharidstruktur auf einem ligand für e und p selectin |
| US5882520A (en) | 1995-10-26 | 1999-03-16 | The University Of Montana | Use of arabinogalactan in aqueous two phase extractions |
| US5756098A (en) | 1995-12-12 | 1998-05-26 | The University Of Montana | Methods for the extraction of phytochemicals from fibrous plants in the absence of solvent |
-
1996
- 1996-11-20 US US08/754,225 patent/US6303584B1/en not_active Expired - Lifetime
-
1997
- 1997-11-20 AU AU52665/98A patent/AU736535B2/en not_active Ceased
- 1997-11-20 AT AT97947624T patent/ATE239042T1/de not_active IP Right Cessation
- 1997-11-20 EP EP97947624A patent/EP0939771B1/de not_active Expired - Lifetime
- 1997-11-20 DE DE69721557T patent/DE69721557D1/de not_active Expired - Lifetime
- 1997-11-20 CA CA002272362A patent/CA2272362A1/en not_active Abandoned
- 1997-11-20 WO PCT/US1997/021497 patent/WO1998022512A1/en not_active Ceased
-
1998
- 1998-10-16 US US09/174,232 patent/US6258796B1/en not_active Expired - Lifetime
-
2001
- 2001-04-30 US US09/845,915 patent/US20010036933A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU5266598A (en) | 1998-06-10 |
| AU736535B2 (en) | 2001-08-02 |
| US6258796B1 (en) | 2001-07-10 |
| DE69721557D1 (de) | 2003-06-05 |
| EP0939771A1 (de) | 1999-09-08 |
| CA2272362A1 (en) | 1998-05-28 |
| US6303584B1 (en) | 2001-10-16 |
| EP0939771B1 (de) | 2003-05-02 |
| US20010036933A1 (en) | 2001-11-01 |
| WO1998022512A1 (en) | 1998-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |