ATE239047T1 - Polymere antitumormittel - Google Patents

Polymere antitumormittel

Info

Publication number
ATE239047T1
ATE239047T1 AT95307637T AT95307637T ATE239047T1 AT E239047 T1 ATE239047 T1 AT E239047T1 AT 95307637 T AT95307637 T AT 95307637T AT 95307637 T AT95307637 T AT 95307637T AT E239047 T1 ATE239047 T1 AT E239047T1
Authority
AT
Austria
Prior art keywords
antitumor agents
polymeric antitumor
polymeric
agents
mammal
Prior art date
Application number
AT95307637T
Other languages
English (en)
Inventor
Hwei-Ru Tsou
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE239047T1 publication Critical patent/ATE239047T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/028—Polyamidoamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/595—Polyamides, e.g. nylon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0273—Polyamines containing heterocyclic moieties in the main chain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyamides (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
AT95307637T 1994-11-01 1995-10-26 Polymere antitumormittel ATE239047T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33266194A 1994-11-01 1994-11-01
US08/521,505 US5609867A (en) 1994-11-01 1995-08-29 Polymeric antitumor agents

Publications (1)

Publication Number Publication Date
ATE239047T1 true ATE239047T1 (de) 2003-05-15

Family

ID=26988319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95307637T ATE239047T1 (de) 1994-11-01 1995-10-26 Polymere antitumormittel

Country Status (11)

Country Link
US (1) US5609867A (de)
EP (1) EP0710689B1 (de)
JP (1) JPH08253420A (de)
AT (1) ATE239047T1 (de)
AU (1) AU690740B2 (de)
CA (1) CA2161603A1 (de)
DE (1) DE69530552T2 (de)
DK (1) DK0710689T3 (de)
ES (1) ES2197183T3 (de)
PT (1) PT710689E (de)
TW (1) TW383318B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0874643B1 (de) * 1996-02-15 2001-11-21 J. Paul Santerre Bioresponsive pharmakologisch aktive polymere und daraus hergestellte gegenstände
AU2014293013A1 (en) 2013-07-26 2016-03-17 Race Oncology Ltd. Combinatorial methods to improve the therapeutic benefit of bisantrene

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714993A (en) 1970-11-23 1973-02-06 Hughes Tool Co Valving tube subassembly for percussion bit
US4197249A (en) 1977-08-15 1980-04-08 American Cyanamid Company 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
US4526788A (en) * 1983-03-18 1985-07-02 American Cyanamid Company Polymeric[[(oxazolidinyl)alkyl]amino]anthraquinones
US4520162A (en) * 1983-09-24 1985-05-28 Director-General Of The Agency Of Industrial Science & Technology Polymeric compounds with sustained anti-tumor activity and a method for the preparation thereof
GB8413464D0 (en) 1984-05-25 1984-07-04 Erba Farmitalia Anthracycline-anionic polymer conjugates
DE3768419D1 (de) * 1986-10-07 1991-04-11 Boehringer Biochemia Srl Pharmazeutische zusammensetzungen mit antineoplastischer wirkung.
US5378456A (en) * 1993-03-25 1995-01-03 American Cyanamid Company Antitumor mitoxantrone polymeric compositions

Also Published As

Publication number Publication date
ES2197183T3 (es) 2004-01-01
EP0710689A3 (de) 1996-11-20
JPH08253420A (ja) 1996-10-01
AU3454795A (en) 1996-05-09
CA2161603A1 (en) 1996-05-02
EP0710689A2 (de) 1996-05-08
US5609867A (en) 1997-03-11
EP0710689B1 (de) 2003-05-02
PT710689E (pt) 2003-08-29
DE69530552T2 (de) 2003-11-20
DE69530552D1 (de) 2003-06-05
AU690740B2 (en) 1998-04-30
DK0710689T3 (da) 2003-08-04
TW383318B (en) 2000-03-01

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