ATE240350T1 - Hydroxypropionitril-cyclohexapeptide - Google Patents

Hydroxypropionitril-cyclohexapeptide

Info

Publication number
ATE240350T1
ATE240350T1 AT92308986T AT92308986T ATE240350T1 AT E240350 T1 ATE240350 T1 AT E240350T1 AT 92308986 T AT92308986 T AT 92308986T AT 92308986 T AT92308986 T AT 92308986T AT E240350 T1 ATE240350 T1 AT E240350T1
Authority
AT
Austria
Prior art keywords
hydroxypropionitril
cyclohexapeptides
cyclohexapeptidyl
nucleus
chem
Prior art date
Application number
AT92308986T
Other languages
English (en)
Inventor
James M Balkovec
Robert A Zambias
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE240350T1 publication Critical patent/ATE240350T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT92308986T 1991-10-01 1992-10-01 Hydroxypropionitril-cyclohexapeptide ATE240350T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77101891A 1991-10-01 1991-10-01
US07/936,434 US5348940A (en) 1991-10-01 1992-09-03 Cyclohexapeptidyl hydroxypropionitrile compounds

Publications (1)

Publication Number Publication Date
ATE240350T1 true ATE240350T1 (de) 2003-05-15

Family

ID=27118385

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92308986T ATE240350T1 (de) 1991-10-01 1992-10-01 Hydroxypropionitril-cyclohexapeptide

Country Status (7)

Country Link
US (1) US5348940A (de)
EP (1) EP0535968B1 (de)
JP (1) JPH07100715B2 (de)
AT (1) ATE240350T1 (de)
CA (1) CA2079172C (de)
DE (1) DE69233058T2 (de)
ES (1) ES2195996T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010042916A (ko) * 1998-04-23 2001-05-25 아벤티스 파마 도이칠란트 게엠베하 에키노칸딘계 펩티드를 그의 ｃ4-호모티로신 모노데옥시유사체로 전환시키는 방법
US8048853B2 (en) * 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
WO2010064219A1 (en) 2008-12-04 2010-06-10 Ranbaxy Laboratories Limited Process for the preparation of a novel intermediate for caspofungin

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173629A (en) * 1975-07-08 1979-11-06 Sandoz Ltd. Antibiotic S 31794/F-1
US4320054A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912H nucleus
US4293485A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4287120A (en) * 1979-12-13 1981-09-01 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4968608A (en) * 1987-10-07 1990-11-06 Merck & Co., Inc. Process for antifungal fermentation product
US4931352A (en) * 1987-10-07 1990-06-05 Merck & Co., Inc. Antifungal fermentation product
US5021341A (en) * 1990-03-12 1991-06-04 Merck & Co., Inc. Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol
IL94862A (en) * 1989-06-30 1994-10-07 Merck & Co Inc History of Echinocandin Antifungal Antibiotics, Its Production and Pharmaceutical Preparations Containing It
US5310873A (en) * 1990-03-12 1994-05-10 Merck & Co., Inc. Cyclohexapeptide compound
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
US5021403A (en) * 1990-03-19 1991-06-04 Merck & Co., Inc. Antibiotic agents
US5159059A (en) * 1990-05-29 1992-10-27 Merck & Co., Inc. Process for reduction of certain cyclohexapeptide compounds
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii

Also Published As

Publication number Publication date
US5348940A (en) 1994-09-20
JPH07100715B2 (ja) 1995-11-01
EP0535968A1 (de) 1993-04-07
CA2079172A1 (en) 1993-04-02
JPH06234794A (ja) 1994-08-23
CA2079172C (en) 2001-04-24
DE69233058T2 (de) 2004-03-04
DE69233058D1 (de) 2003-06-18
EP0535968B1 (de) 2003-05-14
ES2195996T3 (es) 2003-12-16

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Legal Events

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