ATE240923T1 - Herstellung von arylethern sowie damit verbundene reagentien und verfahren - Google Patents
Herstellung von arylethern sowie damit verbundene reagentien und verfahrenInfo
- Publication number
- ATE240923T1 ATE240923T1 AT97910139T AT97910139T ATE240923T1 AT E240923 T1 ATE240923 T1 AT E240923T1 AT 97910139 T AT97910139 T AT 97910139T AT 97910139 T AT97910139 T AT 97910139T AT E240923 T1 ATE240923 T1 AT E240923T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- methods
- aryl ethers
- associated reagents
- reagents
- Prior art date
Links
- 150000008378 aryl ethers Chemical class 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- -1 vinyl ether compound Chemical class 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001336 alkenes Chemical class 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 229910052759 nickel Inorganic materials 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/24—Anthracenes; Hydrogenated anthracenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Steroid Compounds (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/728,449 US5847166A (en) | 1996-10-10 | 1996-10-10 | Synthesis of aryl ethers |
| PCT/US1997/018719 WO1998015515A1 (en) | 1996-10-10 | 1997-10-10 | Synthesis of aryl ethers, methods and reagents related thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE240923T1 true ATE240923T1 (de) | 2003-06-15 |
Family
ID=24926897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97910139T ATE240923T1 (de) | 1996-10-10 | 1997-10-10 | Herstellung von arylethern sowie damit verbundene reagentien und verfahren |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US5847166A (de) |
| EP (3) | EP1254884A3 (de) |
| JP (1) | JP2001501954A (de) |
| AT (1) | ATE240923T1 (de) |
| AU (1) | AU4759297A (de) |
| CA (1) | CA2267153C (de) |
| DE (1) | DE69722271T2 (de) |
| DK (1) | DK1027316T3 (de) |
| ES (1) | ES2200162T3 (de) |
| PT (1) | PT1027316E (de) |
| WO (1) | WO1998015515A1 (de) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5847166A (en) * | 1996-10-10 | 1998-12-08 | Massachusetts Institute Of Technology | Synthesis of aryl ethers |
| DE19725872A1 (de) * | 1997-06-18 | 1998-12-24 | Basf Ag | Verfahren zur Herstellung von Butenylethern |
| US6323366B1 (en) | 1997-07-29 | 2001-11-27 | Massachusetts Institute Of Technology | Arylamine synthesis |
| US6057456A (en) * | 1997-10-16 | 2000-05-02 | Yale University | Transition metal-catalyzed process for preparing alpha-arylated carbonyl-containing compounds |
| US5977361A (en) * | 1997-10-16 | 1999-11-02 | Yale University | Transition metal-catalyzed process for preparing N-aryl compounds |
| US6414173B1 (en) | 1998-07-02 | 2002-07-02 | University Of Maryland | Hypervalent silane and siloxane derivatives and the use thereof |
| US7223879B2 (en) | 1998-07-10 | 2007-05-29 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| JP5035813B2 (ja) * | 1998-07-10 | 2012-09-26 | マサチューセッツ インスティテュート オブ テクノロジー | 金属用のリガンドおよびそれらに基づいて改善された金属触媒法 |
| EP1354887B1 (de) * | 1998-07-10 | 2007-04-25 | Massachussetts Institute of Technology | Ligande für Metalle und verbesserte Metall-katalysierte Verfahren, die darauf basieren |
| US6395916B1 (en) | 1998-07-10 | 2002-05-28 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| US6307087B1 (en) | 1998-07-10 | 2001-10-23 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| US6100398A (en) * | 1998-10-14 | 2000-08-08 | Yale University | Transition metal-catalyzed process for preparing N-aryl amine compounds |
| CA2391966A1 (en) | 1999-11-24 | 2001-05-31 | Massachusetts Institute Of Technology | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries |
| US6562989B2 (en) | 2000-08-07 | 2003-05-13 | Yale University | Catalyst for aromatic C—O, C—N, and C—C bond formation |
| DE10222330A1 (de) * | 2002-05-17 | 2003-11-27 | Degussa | Verfahren zur katalysatorfreien Herstellung von Alkoxybenzonitrilen |
| US6489512B1 (en) | 2002-06-21 | 2002-12-03 | Rhodia Chirex Inc. | Method for making aryl hydrazines and substituted indoles |
| EA009902B1 (ru) | 2004-02-13 | 2008-04-28 | УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си | Модуляторы рецепторов андрогенов |
| JP2007532621A (ja) * | 2004-04-13 | 2007-11-15 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | アンドロゲンモジュレータ |
| US7138555B2 (en) | 2004-04-20 | 2006-11-21 | Xerox Corporation | Process for preparing iodoaromatic compounds and using the same |
| BRPI0509980A (pt) * | 2004-04-22 | 2007-10-16 | Warner Lambert Co | moduladores de androgênio |
| MXPA06015169A (es) * | 2004-07-08 | 2007-08-21 | Warner Lambert Co | Moduladores de androgenos. |
| US20080064745A1 (en) * | 2004-08-18 | 2008-03-13 | Warner-Lambert Company Llc | Androgen Modulators |
| TW200724139A (en) * | 2005-05-05 | 2007-07-01 | Warner Lambert Co | Androgen modulators |
| US20090170886A1 (en) * | 2005-08-08 | 2009-07-02 | Pfizer Inc | Androgen modulators |
| MX394214B (es) * | 2007-03-12 | 2025-03-24 | Intra Cellular Therapies Inc | Sintesis de gamma-carbolinas fusionadas con heterociclo substituido. |
| CN101952298B (zh) | 2007-12-12 | 2015-06-17 | 麻省理工学院 | 用于过渡金属催化的交联偶合反应的配体及其使用方法 |
| JP2011526301A (ja) * | 2008-06-27 | 2011-10-06 | フューチャーフューエル ケミカル カンパニー | アルキルアリールエーテル製造の系および方法 |
| JP2010202589A (ja) * | 2009-03-04 | 2010-09-16 | Kuraray Co Ltd | ２，３−ジヒドロ−チエノ［３，４−ｂ］フラン誘導体の製造方法、及びそれに用いられる新規化合物 |
| WO2011100438A2 (en) | 2010-02-10 | 2011-08-18 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Molecular thermoelectric device |
| CA2936749C (en) | 2010-06-11 | 2019-07-09 | Rhodes Technologies | Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof |
| US8841487B2 (en) | 2010-07-16 | 2014-09-23 | Abbvie Inc. | Phosphine ligands for catalytic reactions |
| US8975443B2 (en) | 2010-07-16 | 2015-03-10 | Abbvie Inc. | Phosphine ligands for catalytic reactions |
| NZ705225A (en) | 2010-07-16 | 2016-11-25 | Abbvie Bahamas Ltd | Process for preparing antiviral compounds |
| US9255074B2 (en) | 2010-07-16 | 2016-02-09 | Abbvie Inc. | Process for preparing antiviral compounds |
| US9428506B2 (en) | 2012-04-14 | 2016-08-30 | Intra-Cellular Therapies, Inc. | Substituted pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines for the treatment of nervous system disorders |
| CA2903281C (en) | 2013-03-08 | 2022-11-29 | The University Of British Columbia | Substituted organofluoroborates as imaging agents |
| KR102967223B1 (ko) | 2013-12-03 | 2026-05-19 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 신규한 방법 |
| KR20220054908A (ko) | 2014-04-04 | 2022-05-03 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 유기 화합물 |
| US9745300B2 (en) | 2014-04-04 | 2017-08-29 | Intra-Cellular Therapies, Inc. | Organic compounds |
| JP6476396B2 (ja) * | 2015-03-10 | 2019-03-06 | 国立大学法人名古屋大学 | 環化触媒、クロマン類の製法及びピロリジン類の製法 |
| RU2743513C2 (ru) | 2016-01-26 | 2021-02-19 | Интра-Селлулар Терапиз, Инк. | Органические соединения |
| IL281050B2 (en) | 2016-03-25 | 2023-04-01 | Intra Cellular Therapies Inc | A controlled or delayed release pharmaceutical preparation containing a deuterated compound |
| WO2017172784A1 (en) | 2016-03-28 | 2017-10-05 | Intra-Cellular Therapies, Inc. | Novel salts and crystals |
| US10682354B2 (en) | 2016-03-28 | 2020-06-16 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| WO2017172811A1 (en) | 2016-03-28 | 2017-10-05 | Intra-Cellular Therapies, Inc. | Novel co-crystals |
| JP7013454B2 (ja) | 2016-10-12 | 2022-02-15 | イントラ－セルラー・セラピーズ・インコーポレイテッド | アモルファス固体分散体 |
| EP3562484B1 (de) | 2016-12-29 | 2021-08-25 | Intra-Cellular Therapies, Inc. | Pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalinderivate zur behandlung von erkrankungen des zns |
| WO2018126140A1 (en) | 2016-12-29 | 2018-07-05 | Intra-Cellular Therapies, Inc. | Organic compounds |
| EP3600325A4 (de) | 2017-03-24 | 2021-01-06 | Intra-Cellular Therapies, Inc. | Neuartige zusammensetzungen und verfahren |
| WO2019023062A1 (en) | 2017-07-26 | 2019-01-31 | Intra-Cellular Therapies, Inc. | ORGANIC COMPOUNDS |
| JP7224333B2 (ja) | 2017-07-26 | 2023-02-17 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 有機化合物 |
| AU2019240226B2 (en) | 2018-03-23 | 2024-11-28 | Intra-Cellular Therapies, Inc. | Organic compounds |
| SMT202600133T1 (it) | 2018-03-23 | 2026-05-12 | Intra Cellular Therapies Inc | Composti organici |
| BR112020024885A2 (pt) | 2018-06-06 | 2021-03-09 | Intra-Cellular Therapies, Inc. | Novos sais e cristais |
| EP3801527B1 (de) | 2018-06-08 | 2025-02-19 | Intra-Cellular Therapies, Inc. | Anellierte gamma-carboline zur akutbehandlung von angst oder depression |
| RS67906B1 (sr) | 2018-06-11 | 2026-04-30 | Intra Cellular Therapies Inc | Sinteza supstituisanih heterociklično fuzionisanih gama-karbolina |
| US11560347B2 (en) | 2018-06-26 | 2023-01-24 | Daikin Industries, Ltd. | Method for producing fluorovinyl ether compound |
| US12144808B2 (en) | 2018-08-29 | 2024-11-19 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| AU2019328528B2 (en) | 2018-08-31 | 2025-01-23 | Intra-Cellular Therapies, Inc. | Novel methods |
| WO2020047408A1 (en) | 2018-08-31 | 2020-03-05 | Intra-Cellular Therapies, Inc. | Novel methods |
| ES3047409T3 (en) | 2018-12-17 | 2025-12-03 | Intra Cellular Therapies Inc | Substituted heterocycle fused gamma-carbolines synthesis |
| IL315005B2 (en) | 2018-12-17 | 2026-04-01 | Intra Cellular Therapies Inc | Substituted heterocycle fused gamma-carbolines synthesis |
| CA3118223A1 (en) | 2018-12-18 | 2020-06-25 | Provincial Health Services Authority | Dual mode 18f-labelled theranostic compounds and uses thereof |
| WO2022082312A1 (en) | 2020-10-21 | 2022-04-28 | Provincial Health Services Authority | Novel cxcr4-targeting compounds |
| US12414948B2 (en) | 2022-05-18 | 2025-09-16 | Intra-Cellular Therapies, Inc. | Methods |
| WO2026063557A1 (ko) * | 2024-09-20 | 2026-03-26 | 한국과학기술연구원 | 신규 단량체 및 이를 포함하는 화학적 재활용이 가능한 고분자 소재 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE734904A (de) * | 1969-04-10 | 1969-12-22 | ||
| US5847166A (en) * | 1996-10-10 | 1998-12-08 | Massachusetts Institute Of Technology | Synthesis of aryl ethers |
-
1996
- 1996-10-10 US US08/728,449 patent/US5847166A/en not_active Expired - Lifetime
-
1997
- 1997-10-10 ES ES97910139T patent/ES2200162T3/es not_active Expired - Lifetime
- 1997-10-10 AT AT97910139T patent/ATE240923T1/de active
- 1997-10-10 DE DE69722271T patent/DE69722271T2/de not_active Expired - Lifetime
- 1997-10-10 PT PT97910139T patent/PT1027316E/pt unknown
- 1997-10-10 DK DK97910139T patent/DK1027316T3/da active
- 1997-10-10 AU AU47592/97A patent/AU4759297A/en not_active Abandoned
- 1997-10-10 JP JP10517804A patent/JP2001501954A/ja not_active Ceased
- 1997-10-10 EP EP02012284A patent/EP1254884A3/de not_active Withdrawn
- 1997-10-10 EP EP97910139A patent/EP1027316B1/de not_active Expired - Lifetime
- 1997-10-10 WO PCT/US1997/018719 patent/WO1998015515A1/en not_active Ceased
- 1997-10-10 EP EP02012164A patent/EP1245553A3/de not_active Withdrawn
- 1997-10-10 CA CA002267153A patent/CA2267153C/en not_active Expired - Fee Related
-
1998
- 1998-12-08 US US09/206,820 patent/US6166226A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6166226A (en) | 2000-12-26 |
| WO1998015515A1 (en) | 1998-04-16 |
| EP1245553A3 (de) | 2003-12-10 |
| CA2267153A1 (en) | 1998-04-16 |
| EP1254884A3 (de) | 2003-12-10 |
| EP1254884A2 (de) | 2002-11-06 |
| ES2200162T3 (es) | 2004-03-01 |
| EP1027316B1 (de) | 2003-05-21 |
| DE69722271T2 (de) | 2004-04-01 |
| DE69722271D1 (de) | 2003-06-26 |
| PT1027316E (pt) | 2003-10-31 |
| DK1027316T3 (da) | 2003-09-15 |
| EP1027316A1 (de) | 2000-08-16 |
| US5847166A (en) | 1998-12-08 |
| EP1245553A2 (de) | 2002-10-02 |
| CA2267153C (en) | 2004-07-20 |
| AU4759297A (en) | 1998-05-05 |
| JP2001501954A (ja) | 2001-02-13 |
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