ATE241013T1 - Hepatitis b virale polypeptide - Google Patents

Hepatitis b virale polypeptide

Info

Publication number
ATE241013T1
ATE241013T1 AT98944071T AT98944071T ATE241013T1 AT E241013 T1 ATE241013 T1 AT E241013T1 AT 98944071 T AT98944071 T AT 98944071T AT 98944071 T AT98944071 T AT 98944071T AT E241013 T1 ATE241013 T1 AT E241013T1
Authority
AT
Austria
Prior art keywords
hepatitis
fragment
viral polypeptides
hbv
polypeptide
Prior art date
Application number
AT98944071T
Other languages
English (en)
Inventor
Steven Neville Chatfield
Original Assignee
Celltech Pharma Europ Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech Pharma Europ Ltd filed Critical Celltech Pharma Europ Ltd
Application granted granted Critical
Publication of ATE241013T1 publication Critical patent/ATE241013T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98944071T 1997-09-19 1998-09-21 Hepatitis b virale polypeptide ATE241013T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9720033.1A GB9720033D0 (en) 1997-09-19 1997-09-19 Hepatitis B virus polypeptides
PCT/GB1998/002852 WO1999015671A1 (en) 1997-09-19 1998-09-21 Hepatitis b virus polypeptides

Publications (1)

Publication Number Publication Date
ATE241013T1 true ATE241013T1 (de) 2003-06-15

Family

ID=10819394

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98944071T ATE241013T1 (de) 1997-09-19 1998-09-21 Hepatitis b virale polypeptide

Country Status (15)

Country Link
US (1) US20040258709A1 (de)
EP (1) EP1015593B1 (de)
JP (1) JP2001517447A (de)
KR (1) KR100637282B1 (de)
AT (1) ATE241013T1 (de)
AU (1) AU751646B2 (de)
CA (1) CA2304255C (de)
CZ (1) CZ297131B6 (de)
DE (1) DE69814884T2 (de)
ES (1) ES2199460T3 (de)
GB (1) GB9720033D0 (de)
HU (1) HUP0003511A3 (de)
NO (1) NO20001397L (de)
PL (1) PL195242B1 (de)
WO (1) WO1999015671A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009470D0 (en) 2000-04-17 2000-06-07 Univ Southampton Materials and methods relating to immune responses to fusion proteins
EP1281761A1 (de) * 2001-07-27 2003-02-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Synthetische Polypeptide die vom pre-S1 Protein des Hepatitis B Virus ableitbar sind und deren Verwendung
EP1638601B1 (de) * 2003-06-23 2008-11-19 Baxter International Inc. Trägerproteine für impfstoffe
CN100537762C (zh) * 2004-06-24 2009-09-09 中国人民解放军军事医学科学院野战输血研究所 一种嵌合型病毒样颗粒疫苗载体蛋白及其制备方法与应用
ES2728243T3 (es) 2012-11-12 2019-10-23 Univ Heidelberg Ruprecht Karls Lipopéptidos para su uso en el tratamiento de enfermedades hepáticas y enfermedades cardiovasculares
AU2024313135A1 (en) * 2023-06-23 2026-01-22 Brii Biosciences, Inc. Assessment and treatment of chronic hepatitis b

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300213A1 (de) * 1987-06-22 1989-01-25 Hexal-Pharma Gentechnik GmbH & Co. KG Virale, immunogen wirksame Peptidpartikel von Hepatitis A
EP0389983A3 (de) * 1989-03-31 1991-01-16 Abbott Laboratories Monoklonale Antikörper gegen PreS2- und PreS1-Polypeptide des Umhüllungsproteins des Hepatite B-Virus
AU4659993A (en) * 1992-07-07 1994-01-31 Merck & Co., Inc. Vaccine comprising mixed pres1+pres2+s and core particle
ATE174628T1 (de) * 1992-07-31 1999-01-15 Medeva Holdings Bv Expression rekombinanter fusionsproteine in attenuierten bakterien
CA2168459C (en) * 1993-07-30 2002-10-01 Mohammed Anjam Khan Fusion proteins containing the c-terminal of tetanus toxin linked to a heterologous protein
GB9401795D0 (en) * 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccines

Also Published As

Publication number Publication date
US20040258709A1 (en) 2004-12-23
EP1015593A1 (de) 2000-07-05
EP1015593B1 (de) 2003-05-21
HUP0003511A2 (hu) 2001-02-28
NO20001397L (no) 2000-05-05
HUP0003511A3 (en) 2003-08-28
NO20001397D0 (no) 2000-03-17
ES2199460T3 (es) 2004-02-16
CZ297131B6 (cs) 2006-09-13
DE69814884T2 (de) 2004-03-11
WO1999015671A1 (en) 1999-04-01
CZ2000978A3 (cs) 2001-01-17
PL339366A1 (en) 2000-12-18
KR20010024176A (ko) 2001-03-26
DE69814884D1 (de) 2003-06-26
AU751646B2 (en) 2002-08-22
JP2001517447A (ja) 2001-10-09
CA2304255A1 (en) 1999-04-01
PL195242B1 (pl) 2007-08-31
CA2304255C (en) 2009-07-07
KR100637282B1 (ko) 2006-10-24
GB9720033D0 (en) 1997-11-19
AU9174498A (en) 1999-04-12

Similar Documents

Publication Publication Date Title
ATE236262T1 (de) Rekombinanter schweinepocken-virus
EP0608261A4 (de) Zusammensetzung aus einem immunreaktiven hepatitis-c-virus-polypeptid.
DE68903165D1 (de) Rns des genoms des non-a, non-b-hepatitisvirus und antigenisches virales protein.
DE69433971D1 (de) Von menschlichen T-Zellen immunodominante Epitopen des Virus der C-Hepatitis
ATE229543T1 (de) Polypeptide des hepatitis c-virus (hiv)
ATE340859T1 (de) Rekombinantes papillomavirus l1 protein
DK11789D0 (da) Rekombinante vaccinia-vira
YU312779A (en) Process for producing polypeptides, processing antigenicity of viral antigens of hepatitis b.
DK1294893T3 (da) Modifikation af hepatitis B-kerneantigen
NZ518999A (en) Vaccine compositions
DK0698216T4 (da) Fremgangsmåder til typebestemmelse af hepatitis-C-virus og anvendte reagenser heri
FI910127A7 (fi) Ei-A-, ei-B-hepatiittiviruksen perimän cDNA ja antigeenipolypeptidi
MXPA03006971A (es) Tratamiento del virus de hepatitis b.
ATE241013T1 (de) Hepatitis b virale polypeptide
ATE473997T1 (de) Zur bildung von partikeln fähiges hbv-precore- protein
FR2815634B1 (fr) Anticorps monoclonaux diriges contre des virus de l'hepatite b
TR199501557A2 (tr) PreS2 peptid iceren hepatiti b viral yüzey antijenini aritma prosesi.
WO1993017110A3 (en) A recombinant hepatitis c virus polypeptide
TR200201954T2 (tr) Viral hastalıklar için tıbbi maddeler.
DE122007000003I1 (de) Gegen mumps Impfstoff, der ein Virus des Jeryl-Lynn Stammes enthält
ATE409705T1 (de) Pre-s-protein von hepatitis-b-virus (hbv) als adjuvans und komponente eines hbv-impfstoffs
WO2001093804A3 (en) Hepatitis c virus conjugates
GR3036125T3 (en) Recombinant proteins having the immunoreactivity of Hepatitis B virus e antigens (HBeAg), method for their production and their application in immunoassays and as vaccines.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties