ATE242237T1 - Benzimidazolverbindungen zur anwendung als therapeutisch wirksame substanzen, verfahren zur herstellung dieser verbindungen und pharmazeutische zusammensetzungen die diese enthalten - Google Patents

Benzimidazolverbindungen zur anwendung als therapeutisch wirksame substanzen, verfahren zur herstellung dieser verbindungen und pharmazeutische zusammensetzungen die diese enthalten

Info

Publication number: ATE242237T1
Authority: AT; Austria
Prior art keywords: alkyl; substituted; aryl; compounds; producing
Prior art date: 1999-01-25

Application number

AT00902282T

Other languages

English (en)

Inventor

Charles Hedgecock

Eric Desarbre

Guido Kurz

Martin Norin

Marguerite Luthman

Hl Cathrin Widerst

Original Assignee

Pharmacia Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-25

Filing date

2000-01-24

Publication date

2003-06-15

2000-01-24 Application filed by Pharmacia Ab filed Critical Pharmacia Ab

2003-06-15 Application granted granted Critical

2003-06-15 Publication of ATE242237T1 publication Critical patent/ATE242237T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 2
150000001556 benzimidazoles Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
239000000126 substance Substances 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 5
125000003107 substituted aryl group Chemical group 0.000 abstract 5
102000002265 Human Growth Hormone Human genes 0.000 abstract 4
108010000521 Human Growth Hormone Proteins 0.000 abstract 4
239000000854 Human Growth Hormone Substances 0.000 abstract 4
125000003118 aryl group Chemical group 0.000 abstract 4
125000000547 substituted alkyl group Chemical group 0.000 abstract 3
101100079984 Caenorhabditis elegans nhr-9 gene Proteins 0.000 abstract 2
125000002877 alkyl aryl group Chemical group 0.000 abstract 2
VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 abstract 2
101100134927 Gallus gallus COR8 gene Proteins 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
101001043818 Mus musculus Interleukin-31 receptor subunit alpha Proteins 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Dermatology (AREA)
Neurology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT00902282T 1999-01-25 2000-01-24 Benzimidazolverbindungen zur anwendung als therapeutisch wirksame substanzen, verfahren zur herstellung dieser verbindungen und pharmazeutische zusammensetzungen die diese enthalten ATE242237T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9900211A SE9900211D0 (sv)	1999-01-25	1999-01-25	New compounds
PCT/SE2000/000144 WO2000043387A1 (en)	1999-01-25	2000-01-24	New benzimidazole compounds for use as active therapeutic substances, process for the preparation of these compoudns and pharmaceutical compositions comprising them

Publications (1)

Publication Number	Publication Date
ATE242237T1 true ATE242237T1 (de)	2003-06-15

Family

ID=20414207

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00902282T ATE242237T1 (de)	1999-01-25	2000-01-24	Benzimidazolverbindungen zur anwendung als therapeutisch wirksame substanzen, verfahren zur herstellung dieser verbindungen und pharmazeutische zusammensetzungen die diese enthalten

Country Status (12)

Country	Link
EP (1)	EP1155014B1 (de)
JP (1)	JP2002535325A (de)
AT (1)	ATE242237T1 (de)
AU (1)	AU760346B2 (de)
CA (1)	CA2359107A1 (de)
DE (1)	DE60003158T2 (de)
DK (1)	DK1155014T3 (de)
ES (1)	ES2202045T3 (de)
NZ (1)	NZ512597A (de)
PT (1)	PT1155014E (de)
SE (1)	SE9900211D0 (de)
WO (1)	WO2000043387A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102361857B (zh) *	2008-09-26	2015-09-16	默沙东公司	可用作抗糖尿病剂的环状苯并咪唑衍生物
GB0908394D0 (en)	2009-05-15	2009-06-24	Univ Leuven Kath	Novel viral replication inhibitors
GB0913636D0 (en) *	2009-08-05	2009-09-16	Univ Leuven Kath	Novel viral replication inhibitors
MX2013005478A (es)	2010-11-15	2013-08-29	Univ Leuven Kath	Compuestos heterociclicos condensados antivirales.

1999
- 1999-01-25 SE SE9900211A patent/SE9900211D0/xx unknown
2000
- 2000-01-24 WO PCT/SE2000/000144 patent/WO2000043387A1/en not_active Ceased
- 2000-01-24 NZ NZ512597A patent/NZ512597A/en unknown
- 2000-01-24 ES ES00902282T patent/ES2202045T3/es not_active Expired - Lifetime
- 2000-01-24 AU AU23406/00A patent/AU760346B2/en not_active Ceased
- 2000-01-24 CA CA002359107A patent/CA2359107A1/en not_active Abandoned
- 2000-01-24 EP EP00902282A patent/EP1155014B1/de not_active Expired - Lifetime
- 2000-01-24 PT PT00902282T patent/PT1155014E/pt unknown
- 2000-01-24 AT AT00902282T patent/ATE242237T1/de not_active IP Right Cessation
- 2000-01-24 JP JP2000594803A patent/JP2002535325A/ja not_active Withdrawn
- 2000-01-24 DE DE60003158T patent/DE60003158T2/de not_active Expired - Fee Related
- 2000-01-24 DK DK00902282T patent/DK1155014T3/da active

Also Published As

Publication number	Publication date
AU2340600A (en)	2000-08-07
JP2002535325A (ja)	2002-10-22
ES2202045T3 (es)	2004-04-01
DK1155014T3 (da)	2003-09-29
EP1155014A1 (de)	2001-11-21
SE9900211D0 (sv)	1999-01-25
DE60003158T2 (de)	2003-12-04
CA2359107A1 (en)	2000-07-27
NZ512597A (en)	2003-12-19
PT1155014E (pt)	2003-10-31
AU760346B2 (en)	2003-05-15
EP1155014B1 (de)	2003-06-04
WO2000043387A1 (en)	2000-07-27
DE60003158D1 (de)	2003-07-10

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2003-12-15

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