ATE384066T1 - Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren - Google Patents

Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren

Info

Publication number
ATE384066T1
ATE384066T1 AT03748242T AT03748242T ATE384066T1 AT E384066 T1 ATE384066 T1 AT E384066T1 AT 03748242 T AT03748242 T AT 03748242T AT 03748242 T AT03748242 T AT 03748242T AT E384066 T1 ATE384066 T1 AT E384066T1
Authority
AT
Austria
Prior art keywords
sup
thieno
releasing hormone
antagonists
gonadotropin
Prior art date
Application number
AT03748242T
Other languages
English (en)
Inventor
Jean Claude Arnould
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE384066T1 publication Critical patent/ATE384066T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT03748242T 2002-08-21 2003-08-18 Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren ATE384066T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02292076 2002-08-21

Publications (1)

Publication Number Publication Date
ATE384066T1 true ATE384066T1 (de) 2008-02-15

Family

ID=31896981

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03748242T ATE384066T1 (de) 2002-08-21 2003-08-18 Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren

Country Status (8)

Country Link
US (1) US7317010B2 (de)
EP (1) EP1532154B1 (de)
JP (1) JP2006508050A (de)
AT (1) ATE384066T1 (de)
AU (1) AU2003267551A1 (de)
DE (1) DE60318716T2 (de)
ES (1) ES2298545T3 (de)
WO (1) WO2004018479A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA200500114A1 (ru) * 2002-06-28 2005-06-30 Еуро-Селтик, С. А. Терапевтические агенты, используемые для лечения боли
TW200407127A (en) * 2002-08-21 2004-05-16 Astrazeneca Ab Chemical compounds
MXPA06000957A (es) 2003-07-31 2006-03-30 Wyeth Corp Compuestos de n-sulfonil heterociclopirrolilalquilamina como ligandos de 5-hidroxitriptamina-6.
WO2005079805A1 (en) * 2004-02-20 2005-09-01 Astrazeneca Ab Pyrrole derivatives as gonadotropin releasing hormone (gnrh) antagonists
EP1730155A1 (de) * 2004-02-20 2006-12-13 AstraZeneca AB Thienopyrrole als antagonisten von gnrh
GB0403781D0 (en) * 2004-02-20 2004-03-24 Astrazeneca Ab Chemical compounds
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
US8071624B2 (en) 2004-06-24 2011-12-06 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals
US10047066B2 (en) 2007-11-30 2018-08-14 Newlink Genetics Corporation IDO inhibitors
EP2739144A4 (de) * 2011-06-20 2015-04-01 Alzheimer S Inst Of America Inc Verbindungen und ihre therapeutische verwendung

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JPH04356029A (ja) 1990-07-02 1992-12-09 Japan Synthetic Rubber Co Ltd 非線形光学素子
JPH04179949A (ja) 1990-11-15 1992-06-26 Fuji Photo Film Co Ltd 新規な色素形成カプラーおよび該カプラーを用いたハロゲン化銀カラー写真感光材料
US6200957B1 (en) 1995-12-14 2001-03-13 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
SK77598A3 (en) 1995-12-14 1999-01-11 Merck & Co Inc Nonpeptide derivatives, pharmaceutical composition containing them and their use
CN1208412A (zh) 1995-12-14 1999-02-17 麦克公司 促性腺激素释放激素拮抗剂
WO1997021435A1 (en) 1995-12-14 1997-06-19 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
JP3092946B2 (ja) 1995-12-14 2000-09-25 メルク エンド カンパニー インコーポレーテッド ゴナドトロピン放出ホルモン拮抗剤
EP0986385A4 (de) 1997-06-05 2001-05-16 Merck & Co Inc Antagonisten des gonadorelins
WO1998055479A1 (en) 1997-06-05 1998-12-10 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
WO1998055123A1 (en) 1997-06-05 1998-12-10 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
AU7806998A (en) 1997-06-05 1998-12-21 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6156772A (en) 1997-06-05 2000-12-05 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
AU729752B2 (en) 1997-06-05 2001-02-08 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
JP2001520997A (ja) 1997-10-28 2001-11-06 メルク エンド カムパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモン拮抗薬
CA2308454A1 (en) 1997-10-28 1999-05-06 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
CA2317451A1 (en) 1998-02-11 1999-08-19 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
JP2002503661A (ja) 1998-02-11 2002-02-05 メルク エンド カムパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモン拮抗薬
JP2002510631A (ja) 1998-04-02 2002-04-09 メルク エンド カムパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモン拮抗薬
WO1999051233A1 (en) 1998-04-02 1999-10-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
CA2326143A1 (en) 1998-04-02 1999-10-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
AU3117899A (en) 1998-04-02 1999-10-25 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
AU3367999A (en) 1998-04-02 1999-10-25 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
US6025366A (en) 1998-04-02 2000-02-15 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
WO1999051595A1 (en) 1998-04-02 1999-10-14 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
JP2002538204A (ja) 1999-03-10 2002-11-12 メルク エンド カムパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモン拮抗薬としての６−アザインドール化合物
EP1171125A1 (de) 1999-03-10 2002-01-16 Merck & Co., Inc. 6-azaindolverbindungen als antagonisten des gonadotropin freisetzendes hormons
AU3514200A (en) 1999-03-10 2000-09-28 Merck & Co., Inc. 6-azaindole compounds as antagonists of gonadotropin releasing hormone
JP2002538206A (ja) 1999-03-10 2002-11-12 メルク エンド カムパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモン拮抗薬としての６−アザインドール化合物
EP1161431A4 (de) 1999-03-10 2002-04-24 Merck & Co Inc 6-azaindol-verbindungen als antagonisten des gonadotropin-freisetzungs hormones
CA2367121A1 (en) 1999-03-10 2000-09-14 Merck & Co., Inc. 6-azaindole compounds as antagonists of gonadotropin releasing hormone
TWI225863B (en) * 1999-03-24 2005-01-01 Takeda Chemical Industries Ltd Thienopyrimidine compounds, their production and use
WO2001070227A1 (en) 2000-03-17 2001-09-27 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
SE0100566D0 (sv) 2001-02-20 2001-02-20 Astrazeneca Ab Compounds
SE0101692D0 (sv) 2001-05-14 2001-05-14 Astrazeneca Ab Compounds

Also Published As

Publication number Publication date
US7317010B2 (en) 2008-01-08
JP2006508050A (ja) 2006-03-09
ES2298545T3 (es) 2008-05-16
US20060004053A1 (en) 2006-01-05
DE60318716T2 (de) 2009-01-08
AU2003267551A1 (en) 2004-03-11
EP1532154B1 (de) 2008-01-16
WO2004018479A1 (en) 2004-03-04
DE60318716D1 (de) 2008-03-06
EP1532154A1 (de) 2005-05-25

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