ATE242248T1 - Optisch reine analoge der camptothecine - Google Patents

Optisch reine analoge der camptothecine

Info

Publication number
ATE242248T1
ATE242248T1 AT00907714T AT00907714T ATE242248T1 AT E242248 T1 ATE242248 T1 AT E242248T1 AT 00907714 T AT00907714 T AT 00907714T AT 00907714 T AT00907714 T AT 00907714T AT E242248 T1 ATE242248 T1 AT E242248T1
Authority
AT
Austria
Prior art keywords
camptothecines
optically pure
analogues
pure analogues
optically
Prior art date
Application number
AT00907714T
Other languages
English (en)
Inventor
Olivier Lavergne
Dennis Bigg
Christophe Lanco
Alain Rolland
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of ATE242248T1 publication Critical patent/ATE242248T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT00907714T 1999-02-26 2000-02-24 Optisch reine analoge der camptothecine ATE242248T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9902398A FR2790261B1 (fr) 1999-02-26 1999-02-26 Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
PCT/FR2000/000461 WO2000050427A1 (fr) 1999-02-26 2000-02-24 Analogues optiquement purs de la camptothecine

Publications (1)

Publication Number Publication Date
ATE242248T1 true ATE242248T1 (de) 2003-06-15

Family

ID=9542564

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03075924T ATE353902T1 (de) 1999-02-26 2000-02-24 Optisch reine camptothecin-analoge
AT00907714T ATE242248T1 (de) 1999-02-26 2000-02-24 Optisch reine analoge der camptothecine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03075924T ATE353902T1 (de) 1999-02-26 2000-02-24 Optisch reine camptothecin-analoge

Country Status (29)

Country Link
US (1) US7012079B1 (de)
EP (2) EP1165565B1 (de)
JP (1) JP2002537399A (de)
KR (1) KR20010108270A (de)
CN (1) CN1195757C (de)
AR (1) AR022740A1 (de)
AT (2) ATE353902T1 (de)
AU (1) AU772632B2 (de)
BR (1) BR0008526A (de)
CA (1) CA2364705C (de)
CZ (1) CZ20013091A3 (de)
DE (2) DE60003170T2 (de)
DK (1) DK1165565T3 (de)
ES (2) ES2200829T3 (de)
FR (1) FR2790261B1 (de)
HK (1) HK1045514B (de)
HR (1) HRP20010622A2 (de)
HU (1) HUP0200529A3 (de)
IL (2) IL144987A0 (de)
MX (1) MXPA01008658A (de)
MY (1) MY127819A (de)
NO (1) NO327260B1 (de)
NZ (1) NZ514153A (de)
PL (1) PL202393B1 (de)
PT (1) PT1165565E (de)
RU (1) RU2230745C2 (de)
TW (1) TWI268931B (de)
WO (1) WO2000050427A1 (de)
ZA (1) ZA200107738B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
TWI333492B (en) * 2003-11-12 2010-11-21 Smithkline Beecham Cork Ltd Crystalline topotecan hydrochloride product and preparation thereof
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
JP2008513437A (ja) 2004-09-21 2008-05-01 ソシエテ ド コンセイユ ド ルシェルシェ エ ダアップリカーション シャンティフィック（エス．セー．エール．アー．エス．） 有用な中間体の新規製造方法
US8575484B1 (en) 2010-09-14 2013-11-05 Cooper Technologies Company Adjustable-depth ring assembly and method of installation
WO2025255212A1 (en) * 2024-06-07 2025-12-11 Codeable Therapeutics, Incorporated Topoisomerase inhibitors, antibody-drug conjugates comprising them, and methods of their use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
FR2757515B1 (fr) * 1996-12-20 2000-05-05 Sod Conseils Rech Applic Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2768431B1 (fr) * 1997-08-29 2000-03-24 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
DE69623961T2 (de) * 1995-06-21 2003-05-08 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.), Paris Camptothecinanaloge, verfahren zur ihrer herstellung, ihre verwendungals arzneimittel und diese enthaltende pharmazeutische zusammenfassungen
GB9512670D0 (en) * 1995-06-21 1995-08-23 Sod Conseils Rech Applic Camptothecin analogues
KR100516593B1 (ko) * 1996-08-19 2005-09-22 바이오누머릭 파마슈티칼스, 인코포레이티드 고 친유성 캠프토테신 유도체
UA57757C2 (uk) * 1996-12-20 2003-07-15 Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) Аналоги камптотецину, спосіб їх отримання (варіанти) і фармацевтична композиція
ES2262223T3 (es) * 1997-02-14 2006-11-16 Bionumerik Pharmaceuticals, Inc. Derivados de camptotecina altamente lipofilos.
US6207673B1 (en) * 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof

Also Published As

Publication number Publication date
DE60033447T2 (de) 2007-10-31
ZA200107738B (en) 2003-02-26
PL361334A1 (en) 2004-10-04
AR022740A1 (es) 2002-09-04
PT1165565E (pt) 2003-10-31
NO20014117L (no) 2001-10-11
EP1165565B1 (de) 2003-06-04
ES2282564T3 (es) 2007-10-16
WO2000050427A1 (fr) 2000-08-31
ATE353902T1 (de) 2007-03-15
CZ20013091A3 (cs) 2002-05-15
TWI268931B (en) 2006-12-21
RU2230745C2 (ru) 2004-06-20
MXPA01008658A (es) 2002-03-14
NZ514153A (en) 2001-09-28
FR2790261A1 (fr) 2000-09-01
KR20010108270A (ko) 2001-12-07
DE60033447D1 (de) 2007-03-29
HRP20010622A2 (en) 2002-08-31
ES2200829T3 (es) 2004-03-16
CN1345321A (zh) 2002-04-17
CA2364705C (fr) 2010-03-30
DE60003170T2 (de) 2004-04-01
HK1045514A1 (en) 2002-11-29
HUP0200529A3 (en) 2004-03-29
HUP0200529A2 (en) 2002-06-29
DK1165565T3 (da) 2003-10-06
JP2002537399A (ja) 2002-11-05
US7012079B1 (en) 2006-03-14
NO327260B1 (no) 2009-05-25
IL144987A (en) 2006-12-31
EP1338599B1 (de) 2007-02-14
PL202393B1 (pl) 2009-06-30
NO20014117D0 (no) 2001-08-24
AU772632B2 (en) 2004-05-06
BR0008526A (pt) 2002-01-08
CA2364705A1 (fr) 2000-08-31
AU2921000A (en) 2000-09-14
EP1338599A1 (de) 2003-08-27
HK1045514B (zh) 2005-11-18
MY127819A (en) 2006-12-29
IL144987A0 (en) 2002-06-30
FR2790261B1 (fr) 2004-09-10
CN1195757C (zh) 2005-04-06
EP1165565A1 (de) 2002-01-02
DE60003170D1 (en) 2003-07-10

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