DK1165565T3 - Optisk rene camptothecin-analoger - Google Patents

Optisk rene camptothecin-analoger

Info

Publication number
DK1165565T3
DK1165565T3 DK00907714T DK00907714T DK1165565T3 DK 1165565 T3 DK1165565 T3 DK 1165565T3 DK 00907714 T DK00907714 T DK 00907714T DK 00907714 T DK00907714 T DK 00907714T DK 1165565 T3 DK1165565 T3 DK 1165565T3
Authority
DK
Denmark
Prior art keywords
optically pure
camptothecin analogs
pure camptothecin
analogs
optically
Prior art date
Application number
DK00907714T
Other languages
Danish (da)
English (en)
Inventor
Olivier Lavergne
Dennis Bigg
Christophe Lanco
Alain Rolland
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of DK1165565T3 publication Critical patent/DK1165565T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK00907714T 1999-02-26 2000-02-24 Optisk rene camptothecin-analoger DK1165565T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9902398A FR2790261B1 (fr) 1999-02-26 1999-02-26 Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
PCT/FR2000/000461 WO2000050427A1 (fr) 1999-02-26 2000-02-24 Analogues optiquement purs de la camptothecine

Publications (1)

Publication Number Publication Date
DK1165565T3 true DK1165565T3 (da) 2003-10-06

Family

ID=9542564

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00907714T DK1165565T3 (da) 1999-02-26 2000-02-24 Optisk rene camptothecin-analoger

Country Status (29)

Country Link
US (1) US7012079B1 (de)
EP (2) EP1338599B1 (de)
JP (1) JP2002537399A (de)
KR (1) KR20010108270A (de)
CN (1) CN1195757C (de)
AR (1) AR022740A1 (de)
AT (2) ATE242248T1 (de)
AU (1) AU772632B2 (de)
BR (1) BR0008526A (de)
CA (1) CA2364705C (de)
CZ (1) CZ20013091A3 (de)
DE (2) DE60003170T2 (de)
DK (1) DK1165565T3 (de)
ES (2) ES2282564T3 (de)
FR (1) FR2790261B1 (de)
HK (1) HK1045514B (de)
HR (1) HRP20010622A2 (de)
HU (1) HUP0200529A3 (de)
IL (2) IL144987A0 (de)
MX (1) MXPA01008658A (de)
MY (1) MY127819A (de)
NO (1) NO327260B1 (de)
NZ (1) NZ514153A (de)
PL (1) PL202393B1 (de)
PT (1) PT1165565E (de)
RU (1) RU2230745C2 (de)
TW (1) TWI268931B (de)
WO (1) WO2000050427A1 (de)
ZA (1) ZA200107738B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
AR046579A1 (es) * 2003-11-12 2005-12-14 Smithkline Beecham Corp Compuesto cristalino de topotecan, composicion farmaceutica que lo comprende, procedimiento para prepararlo y su uso para preparar dicha composicion farmaceutica
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
JP2008513437A (ja) * 2004-09-21 2008-05-01 ソシエテ ド コンセイユ ド ルシェルシェ エ ダアップリカーション シャンティフィック（エス．セー．エール．アー．エス．） 有用な中間体の新規製造方法
US8575484B1 (en) 2010-09-14 2013-11-05 Cooper Technologies Company Adjustable-depth ring assembly and method of installation
WO2025255212A1 (en) * 2024-06-07 2025-12-11 Codeable Therapeutics, Incorporated Topoisomerase inhibitors, antibody-drug conjugates comprising them, and methods of their use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
FR2768431B1 (fr) 1997-08-29 2000-03-24 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
BR9608639A (pt) * 1995-06-21 1999-06-29 Sod Conseils Rech Applic Análogo de camptotecina composto processo de preparação dos compostos produtoos industriaia medicamentos composições farmacêuticas e utilização de produtos
GB9512670D0 (en) * 1995-06-21 1995-08-23 Sod Conseils Rech Applic Camptothecin analogues
FR2757515B1 (fr) * 1996-12-20 2000-05-05 Sod Conseils Rech Applic Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
IL127800A (en) * 1996-08-19 2005-11-20 Bionumerik Pharmaceuticals Inc Highly lipophilic 7-substituted camptothecin derivatives and pharmaceutical compositions containing them
UA57757C2 (uk) * 1996-12-20 2003-07-15 Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) Аналоги камптотецину, спосіб їх отримання (варіанти) і фармацевтична композиція
ATE329903T1 (de) * 1997-02-14 2006-07-15 Bionumerik Pharmaceuticals Inc Hochgradig lipophile camptothecin-derivate
US6207673B1 (en) * 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof

Also Published As

Publication number Publication date
HUP0200529A2 (en) 2002-06-29
HK1045514B (zh) 2005-11-18
DE60033447T2 (de) 2007-10-31
CN1345321A (zh) 2002-04-17
IL144987A (en) 2006-12-31
PT1165565E (pt) 2003-10-31
EP1165565B1 (de) 2003-06-04
WO2000050427A1 (fr) 2000-08-31
ES2282564T3 (es) 2007-10-16
RU2230745C2 (ru) 2004-06-20
AU2921000A (en) 2000-09-14
NO20014117D0 (no) 2001-08-24
ZA200107738B (en) 2003-02-26
CN1195757C (zh) 2005-04-06
DE60003170T2 (de) 2004-04-01
CA2364705C (fr) 2010-03-30
CA2364705A1 (fr) 2000-08-31
MXPA01008658A (es) 2002-03-14
PL361334A1 (en) 2004-10-04
ES2200829T3 (es) 2004-03-16
DE60033447D1 (de) 2007-03-29
EP1165565A1 (de) 2002-01-02
IL144987A0 (en) 2002-06-30
NO20014117L (no) 2001-10-11
NO327260B1 (no) 2009-05-25
EP1338599A1 (de) 2003-08-27
CZ20013091A3 (cs) 2002-05-15
FR2790261B1 (fr) 2004-09-10
HUP0200529A3 (en) 2004-03-29
HRP20010622A2 (en) 2002-08-31
EP1338599B1 (de) 2007-02-14
JP2002537399A (ja) 2002-11-05
PL202393B1 (pl) 2009-06-30
ATE353902T1 (de) 2007-03-15
FR2790261A1 (fr) 2000-09-01
US7012079B1 (en) 2006-03-14
AU772632B2 (en) 2004-05-06
BR0008526A (pt) 2002-01-08
HK1045514A1 (en) 2002-11-29
ATE242248T1 (de) 2003-06-15
MY127819A (en) 2006-12-29
DE60003170D1 (en) 2003-07-10
AR022740A1 (es) 2002-09-04
KR20010108270A (ko) 2001-12-07
TWI268931B (en) 2006-12-21
NZ514153A (en) 2001-09-28

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