ATE242331T1 - Porphyromonas gingivalis arginin-spezifische proteinase kodierende sequenzen - Google Patents

Porphyromonas gingivalis arginin-spezifische proteinase kodierende sequenzen

Info

Publication number: ATE242331T1
Authority: AT; Austria
Prior art keywords: gingipain; coding sequences; porphyromonas gingivalis; specific; amidolytic
Prior art date: 1993-09-10

Application number

AT94929183T

Other languages

English (en)

Inventor

James Travis

Jan Stanislaw Potempa

Philip J Barr

Nadine Pavloff

Original Assignee

Univ Georgia Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-10

Filing date

1994-09-09

Publication date

2003-06-15

1993-09-10 Priority claimed from US08/119,361 external-priority patent/US5523390A/en

1993-10-21 Priority claimed from US08/141,324 external-priority patent/US5475097A/en

1994-09-09 Application filed by Univ Georgia Res Found filed Critical Univ Georgia Res Found

2003-06-15 Application granted granted Critical

2003-06-15 Publication of ATE242331T1 publication Critical patent/ATE242331T1/de

Links

102000035195 Peptidases Human genes 0.000 title 1
108091005804 Peptidases Proteins 0.000 title 1
241000605862 Porphyromonas gingivalis Species 0.000 title 1
235000019833 protease Nutrition 0.000 title 1
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
101000727041 Porphyromonas gingivalis Gingipain R1 Proteins 0.000 abstract 2
230000003024 amidolytic effect Effects 0.000 abstract 2
238000003776 cleavage reaction Methods 0.000 abstract 2
230000002797 proteolythic effect Effects 0.000 abstract 2
230000007017 scission Effects 0.000 abstract 2
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
108010005843 Cysteine Proteases Proteins 0.000 abstract 1
102000005927 Cysteine Proteases Human genes 0.000 abstract 1
108091020100 Gingipain Cysteine Endopeptidases Proteins 0.000 abstract 1
239000004471 Glycine Substances 0.000 abstract 1
241000605894 Porphyromonas Species 0.000 abstract 1
125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 abstract 1
229910052791 calcium Inorganic materials 0.000 abstract 1
239000011575 calcium Substances 0.000 abstract 1
239000002738 chelating agent Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
238000001502 gel electrophoresis Methods 0.000 abstract 1
238000001641 gel filtration chromatography Methods 0.000 abstract 1
150000002333 glycines Chemical class 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Enzymes And Modification Thereof (AREA)
Cosmetics (AREA)

AT94929183T 1993-09-10 1994-09-09 Porphyromonas gingivalis arginin-spezifische proteinase kodierende sequenzen ATE242331T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US08/119,361 US5523390A (en)	1993-09-10	1993-09-10	Porphyromonas gingivalis arginine-specific proteinase
US08/141,324 US5475097A (en)	1993-10-21	1993-10-21	Lysine-specific Porphyromonas gingivalis proteinase
US26544194A	1994-06-24	1994-06-24
PCT/US1994/010283 WO1995007286A1 (en)	1993-09-10	1994-09-09	Porphyromonas gingivalis arginine-specific proteinase coding sequences

Publications (1)

Publication Number	Publication Date
ATE242331T1 true ATE242331T1 (de)	2003-06-15

Family

ID=27382295

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94929183T ATE242331T1 (de)	1993-09-10	1994-09-09	Porphyromonas gingivalis arginin-spezifische proteinase kodierende sequenzen

Country Status (4)

Country	Link
EP (1)	EP0717747B1 (de)
AT (1)	ATE242331T1 (de)
DE (1)	DE69432795T2 (de)
WO (1)	WO1995007286A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5824791A (en) *	1988-09-08	1998-10-20	University Of Florida	Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease
US5830710A (en) *	1988-09-08	1998-11-03	University Of Florida	Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease
AUPN627595A0 (en) *	1995-10-30	1995-11-23	University Of Melbourne, The	Diagnostics and treatments of periodontal disease
JP2000507245A (ja) *	1996-03-22	2000-06-13	ユニバーシティーオブジョージアリサーチファウンデーション，インコーポレイテッド	Ｐｏｒｐｈｙｒｏｍｏｎａｓｇｉｎｇｉｖａｌｉｓペプチドを含む免疫原性組成物および方法
AUPO652897A0 (en) *	1997-04-30	1997-05-29	University Of Melbourne, The	Synthetic peptide constructs for the diagnosis and treatment of periodontitis
US8129500B2 (en)	1997-12-10	2012-03-06	Csl Limited	Porphyromonas gingivalis polypeptides and nucleotides
WO2000071682A2 (en) *	1999-05-20	2000-11-30	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Crystal structure data of cysteinprotease gingipain r
DE19926728B4 (de)	1999-06-11	2011-08-18	3M Espe Ag, 82229	Verwendung von Trägermaterialien und diagnostisch nutzbaren Zusatzstoffen in Abbildungsverfahren für intraorale Diagnosezwecke
AUPQ485999A0 (en)	1999-12-24	2000-02-03	Csl Limited	P. gingivalis antigenic composition
DE10061195B4 (de)	2000-12-08	2004-12-02	3M Espe Ag	Verwendung von Abformmassen zur Herstellung von Behandlungsvorrichtungen
EP1799705A4 (de)	2004-09-23	2008-11-05	Univ Melbourne	Antigenkomplex zur diagnose und behandlung von porphyromonas-gingivalis-infektion
CA2652957A1 (en)	2006-06-27	2008-01-03	Oral Health Australia Pty Ltd.	Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease
KR101614938B1 (ko)	2007-07-12	2016-04-22	오럴 헬스 오스트레일리아 피티와이 엘티디	균막 치료
NZ582438A (en)	2007-07-12	2012-03-30	Oral Health Australia Pty Ltd	A composition for use in raising an immune response to p. gingivalis
EP3255057B1 (de)	2008-08-29	2020-03-18	Oral Health Australia Pty Ltd	Prävention, behandlung und diagnose einer p.-gingivalis-infektion

1994
- 1994-09-09 AT AT94929183T patent/ATE242331T1/de not_active IP Right Cessation
- 1994-09-09 EP EP94929183A patent/EP0717747B1/de not_active Expired - Lifetime
- 1994-09-09 DE DE69432795T patent/DE69432795T2/de not_active Expired - Lifetime
- 1994-09-09 WO PCT/US1994/010283 patent/WO1995007286A1/en not_active Ceased

Also Published As

Publication number	Publication date
WO1995007286A1 (en)	1995-03-16
EP0717747B1 (de)	2003-06-04
EP0717747A4 (de)	1999-01-13
DE69432795D1 (de)	2003-07-10
EP0717747A1 (de)	1996-06-26
DE69432795T2 (de)	2004-04-29

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Legal Events

Date	Code	Title	Description
2003-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties